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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44332   clinical trials with a EudraCT protocol, of which   7365   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,332 result(s) found. Displaying page 1,786 of 2,217.
    EudraCT Number: 2014-005553-39 Sponsor Protocol Number: 1501 Start Date*: 2015-12-29
    Sponsor Name:Karolinska University Hospital
    Full Title: Effects of Sativex on blood leukocytes in patients with lymphoma/chronic lymphocytic leukaemia
    Medical condition: Lymphoma and chronic lymphocytic leukaemia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-000175-37 Sponsor Protocol Number: 2021-000175-37 Start Date*: 2021-02-09
    Sponsor Name:Karolinska Universitetssjukhuset
    Full Title: Immunological Responses after Vaccination for COVID-19 with the mRNA Vaccine Comirnaty in Immunosuppressed and Immunocompetent Individuals. An open, non-randomized , phase IV multicenter study
    Medical condition: SARS-COV-2 Infection
    Disease: Version SOC Term Classification Code Term Level
    23.0 100000004862 10084272 SARS-CoV-2 infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-021756-26 Sponsor Protocol Number: SOMAQ Start Date*: 2010-11-08
    Sponsor Name:VG Region, Sahlgrenska sjukhuset, Hudkliniken, Göteborg
    Full Title: Behandlingseffekt av UV ljus jämfört med peroralt D vitamin på D-vitaminnivån hos somaliska kvinnor
    Medical condition: - Studera effekten på serum vitamin D-nivåerna före och efter vitamin D behandling av vuxna somaliska kvinnor boende i Sverige. - Jämföra serum vitamin D-nivåerna mellan behandling med peroralt vi...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-001186-12 Sponsor Protocol Number: GMMG-HD10/DSMM-XX/64007957MMY2003 Start Date*: 2022-11-07
    Sponsor Name:Ruprecht-Karls-University Heidelberg, Medical Faculity, represented by University Hospital Heidelberg
    Full Title: A Phase 2 Study to Evaluate Safety and Efficacy of Teclistamab- and Talquetamab-based Combination Regimens in Participants with Newly Diagnosed Transplant Eligible Multiple Myeloma
    Medical condition: Newly Diagnosed Multiple Myeloma in patients eligible for stem cell transplantation
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10028228 Multiple myeloma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2015-003512-20 Sponsor Protocol Number: IN11004 Start Date*: 2016-05-09
    Sponsor Name:Intec Pharma, Ltd.
    Full Title: A Phase III, Multicenter, Randomized, Double-Blind, Double-Dummy, Active-Controlled Study Comparing the Efficacy and Safety of Gastric Retentive, Controlled Release Accordion Pill™ Carbidopa/Levodo...
    Medical condition: Parkinson's Disease
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004852 10034005 Parkinson's disease and parkinsonism HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) GB (Completed) SK (Completed) ES (Completed) PL (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-001623-11 Sponsor Protocol Number: OOI/FNY/2005-1 Start Date*: 2006-09-07
    Sponsor Name:National Institute of Oncology
    Full Title: Docetaxellel bövített standard 5-fluorouracil plusz ciszplatin alapú neoadjuváns kemoterápia plusz ciszplatin alapú radiokemoterápia összehasonlítása a standard ciszplatin alapú radiokemoterápiáva...
    Medical condition: Beteganyag III-IV. stádiumú, laphámrák szövettanú szájüreg-, nyelv-, gingíva-, sublingua-, (ajak nem), szájgarat-, algarat- és gégetumoros betegek. (A betegek az Országos Onkológiai Intézet Fej-nya...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004003-38 Sponsor Protocol Number: VAC/04/0101 Start Date*: 2005-04-20
    Sponsor Name:Vakcina Kft
    Full Title: Kettos vak, randomizalt komparativ vizsgalat a Gynevac lactobacillus vakcinaval vegzett kezeles hatekonysaganak es biztonsaganak osszehasonlitasara a hagyomanyos antibiotikus (ofloxacin) kezelessel...
    Medical condition: Chronic prostatitis (with or without hyperplasia of the prostate)
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-024389-23 Sponsor Protocol Number: 114813 Start Date*: 2011-06-07
    Sponsor Name:Department of Hematology
    Full Title: A Phase 2 Trial of Alemtuzumab-Ofatumumab Combination in Previously Untreated Symptomatic Chronic Lymphocytic Leukemia
    Medical condition: Chronic Lymphocytic Leukemia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-004619-28 Sponsor Protocol Number: RITS-PO-2019 Start Date*: 2019-04-24
    Sponsor Name:Region Örebro län
    Full Title: Rituximab - Immunotherapy for Obsessive-Compulsive Disorder. An open pilot study.
    Medical condition: Treatment-resistant patients with Obsessive Compulsive Disorder (OCD)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-012985-29 Sponsor Protocol Number: NM1 Start Date*: 2010-01-11
    Sponsor Name:SU/Mölndal Sjukhus
    Full Title: Kortisondroppar, dexametason 0,1 %, jämfört med kortisondroppar i kombination med nepafenac 0.1% som behandling vid gråstarrskirurgi. En prospektiv, randomiserad, dubbel - maskerad studie
    Medical condition: Det vetenskapliga syftet med denna studie är att undersöka huruvida kombinationsbehandlingen med det nyintroducerade Nevanac® och standardterapi (dvs. enbart Isopto-Maxidex®) kan förebygga risken ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-004618-17 Sponsor Protocol Number: RITS-PS-2019 Start Date*: 2019-04-24
    Sponsor Name:Region Örebro län
    Full Title: Rituximab - Immunotherapy for Schizophrenia spectrum disorder in adults. An open pilot study.
    Medical condition: Treatment-resistant patients with schizophrenia spectrum disorder (SSD)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-002025-11 Sponsor Protocol Number: ALXN1210-PNH-301 Start Date*: 2016-12-02
    Sponsor Name:Alexion Pharmaceuticals Incorporated
    Full Title: A Phase 3, Randomized, Open-Label, Active-Controlled Study of ALXN1210 Versus Eculizumab in Complement Inhibitor-Naïve Adult Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH)
    Medical condition: Paroxysmal Nocturnal Hemoglobinuria (PNH)
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004857 10055629 Paroxysmal nocturnal hemoglobinuria LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) DE (Completed) SE (Completed) BE (Completed) CZ (Completed) DK (Prematurely Ended) PT (Prematurely Ended) FI (Prematurely Ended) ES (Ongoing) NL (Completed) AT (Completed) EE (Completed) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2021-003466-12 Sponsor Protocol Number: MCMK0220 Start Date*: 2022-03-25
    Sponsor Name:MCM Klosterfrau Vertriebsgesellschaft mbH
    Full Title: A double-blind, randomised, multi-centre, controlled clinical trial to compare D-mannose versus antibiotic in the treatment of acute uncomplicated lower urinary tract infections in female patients
    Medical condition: acute uncomplicated lower urinary tract infections
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10024981 Lower urinary tract infection LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-004461-40 Sponsor Protocol Number: IM011-077 Start Date*: 2021-08-04
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: An Open-label, Multi-center Extension Study to Evaluate the Long-term Safety and Efficacy of BMS-986165 in Participants with Moderate to Severe Crohn’s Disease or Moderate to Severe Ulcerative Colitis
    Medical condition: moderate to severe Crohn’s Disease (CD), moderate to severe Ulcerative Colitis (UC)
    Disease: Version SOC Term Classification Code Term Level
    20.1 10017947 - Gastrointestinal disorders 10045365 Ulcerative colitis LLT
    20.0 10017947 - Gastrointestinal disorders 10011401 Crohn's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) IT (Prematurely Ended) ES (Ongoing) PT (Prematurely Ended) NL (Completed)
    Trial results: View results
    EudraCT Number: 2015-004798-34 Sponsor Protocol Number: ATB200-02 Start Date*: 2016-08-01
    Sponsor Name:Amicus Therapeutics, Inc.
    Full Title: AN OPEN-LABEL, FIXED-SEQUENCE, ASCENDING-DOSE, FIRST-IN-HUMAN STUDY TO ASSESS THE SAFETY, TOLERABILITY, PHARMACOKINETICS, PHARMACODYNAMICS, AND EFFICACY OF INTRAVENOUS INFUSIONS OF ATB200 CO-ADMINI...
    Medical condition: Pompe Disease - acid maltase deficiency or glycogen storage disease type II.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004850 10036143 Pompe's disease LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) DE (Completed) NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-002525-19 Sponsor Protocol Number: D5660C00004 Start Date*: 2016-01-27
    Sponsor Name:AstraZeneca AB
    Full Title: A Phase 1b/2, Open-Label, Multicentre Study Assessing the Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-tumor Activity of MEDI4736 in Combination With AZD9150 or AZD5069 in Patients ...
    Medical condition: Part A (US ONLY): advanced solid malignancies Part B (NA, EU): Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck
    Disease: Version SOC Term Classification Code Term Level
    26.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10060121 Squamous cell carcinoma of head and neck PT
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10065147 Malignant solid tumor LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) ES (Restarted) BE (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-002780-30 Sponsor Protocol Number: 9515 Start Date*: 2022-12-01
    Sponsor Name:Aarhus University Hospital, The Research Clinic for Functional Disorders and Psychosomatics
    Full Title: Efficacy of patient education and duloxetine, alone and in combination, for patients with multiorgan bodily distress syndrome: a partial-factorial randomized controlled trial (the EDULOX-trial)
    Medical condition: Multiorgan Functional somatic disorders (FSD) / bodily disstress syndrome (BDS)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004873 10041319 Somatization disorder LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2017-004775-30 Sponsor Protocol Number: Na Start Date*: 2018-05-09
    Sponsor Name:Kirsi Mikkonen/Helsinki University Hospital
    Full Title: PREDICTION AND PREVENTION OF INFANTILE SPASMS IN HIGH RISK CHILDREN
    Medical condition:
    Disease:
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: FI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-001386-81 Sponsor Protocol Number: 2016-1-DSF-MBC Start Date*: 2019-01-11
    Sponsor Name:Univerzita Palackého v Olomouci
    Full Title: PHASE II OPEN LABELED TRIAL OF DISULFIRAM WITH COPPER IN METASTATIC BREAST CANCERS.
    Medical condition: Metastatic breast cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2010-021021-13 Sponsor Protocol Number: 10EU/HMG02 Start Date*: 2010-11-25
    Sponsor Name:IBSA, Institut Biochimique S.A.
    Full Title: Safety and efficacy study comparing a new hMG formulation (hMG-IBSA) to a reference product (Menopur®) in patients undergoing ovarian stimulation for in vitro fertilisation (IVF).
    Medical condition: Patients, with basal FSH <10 IU/L and E2 <80 pg/ml (~290 pmol/l), undergoing controlled ovarian stimulation for in vitro fertilisation.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10056204 In vitro fertilisation LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed) DK (Completed) HU (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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