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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43850   clinical trials with a EudraCT protocol, of which   7282   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    43,850 result(s) found. Displaying page 1,786 of 2,193.
    «« First « Previous 1782  1783  1784  1785  1786  1787  1788  1789  1790  Next» Last»»
    EudraCT Number: 2021-003716-12 Sponsor Protocol Number: RHNIA-001-2021 Start Date*: 2022-08-24
    Sponsor Name:Rigshospitalet
    Full Title: S-ketamine for cortical spreading depolarisation in patients with severe acute brain injury
    Medical condition: Severe acute brain injury caused by aneurysmal subarachnoid hemorrhage, spontaneous intracerebral hemorrhage or traumatic brain injury.
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10018061 General anesthesia LLT
    21.1 100000004865 10070731 Electrocorticography LLT
    20.0 100000004852 10056389 Brain damage LLT
    21.0 100000004852 10019529 Hemorrhage brain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-002028-19 Sponsor Protocol Number: RH-CARD-Pharma001 Start Date*: 2022-02-01
    Sponsor Name:Department of Cardiology, Copenhagen University Hospital Rigshospitalet
    Full Title: Low-dose dobutamine infusion and single-dose tocilizumab in acute myocardial infarction patients with high risk of cardiogenic shock development – a 2x2 multifactorial, double-blinded, randomized, ...
    Medical condition: Acute Myocardial Infarction with increased risk of Cardiogenic Shock.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10000891 Acute myocardial infarction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-004996-14 Sponsor Protocol Number: AK_2021_HP Start Date*: 2022-04-18
    Sponsor Name:Department of Clinical Physiology and Nuclear Medicine, Rigshospitalet
    Full Title: Phase IIa Clinical Trial: Feasibility Study on Non-Invasive Simultaneous Hyperpolarized [1-13C]Pyruvate Magnetic Resonance Spectroscopy and 18F-FDG PET (hyperPET) for Metabolic Imaging in Patients ...
    Medical condition: Breast cancer, neuroendocrine neoplasms
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006192 Breast cancer NOS LLT
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10067518 Pancreatic neuroendocrine tumor LLT
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10062476 Neuroendocrine tumor LLT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10077560 Gastroenteropancreatic neuroendocrine tumor disease LLT
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10068916 Pancreatic neuroendocrine tumor metastatic LLT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10057270 Neuroendocrine carcinoma PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10071542 Neuroendocrine carcinoma metastatic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-003265-26 Sponsor Protocol Number: 345 Start Date*: 2017-01-03
    Sponsor Name:Medical University of Vienna
    Full Title: Pharmacokinetic/Pharmacodynamic effects of add-on antiplatelet therapy with parenteral cangrelor as compared to standard dual antiplatelet treatment in patients with ST-elevation myocardial infarct...
    Medical condition: ST-elevation myocardial infarction, cardiac arrest
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: View results
    EudraCT Number: 2016-001313-24 Sponsor Protocol Number: SUPERADD Start Date*: 2017-02-13
    Sponsor Name:Technische Universität München, Fakultät für Medizin
    Full Title: SUbstition of PERioperative Albumin Deficiency Disorders
    Medical condition: High risk surgical patients or procedures showing a hypoalbuminemia intraoperatively.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022891 - Investigations 10005286 Blood albumin abnormal PT
    20.0 10022891 - Investigations 10005287 Blood albumin decreased PT
    20.1 10027433 - Metabolism and nutrition disorders 10020943 Hypoalbuminemia LLT
    20.0 10027433 - Metabolism and nutrition disorders 10020942 Hypoalbuminaemia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-005014-30 Sponsor Protocol Number: AlproECMO_1.0 Start Date*: 2016-06-02
    Sponsor Name:Medical University of Vienna, Department of Internal medicine I
    Full Title: A prospective randomized, double blind study on safety and efficacy of Alprostadil as additional Anticoagulant in Patients with veno- venous ECMO
    Medical condition: pulmonary insufficiency, which cannot be treated with measures of mechanical ventilation alone, Conditions in which veno-venous extracorporeal membrane oxygenation therapy is indicated
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004855 10069144 Acute respiratory insufficiency LLT
    19.0 100000004855 10038701 Respiratory insufficiency LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2016-004537-25 Sponsor Protocol Number: ET16-116 Start Date*: 2017-11-06
    Sponsor Name:Centre Léon Bérard
    Full Title: An Phase II trial aiming to evaluate the clinical interest of ABEMACICLIB monotherapy in patients with locally advanced/metastatic head and neck cancer after failure of platinum and cetuximab or an...
    Medical condition: Patients with locally advanced/metastatic head and neck cancer after failure of platinum and cetuximab or anti-EGFR-based
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10067821 Head and neck cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-003415-19 Sponsor Protocol Number: JM-010CS03 Start Date*: 2018-10-31
    Sponsor Name:Contera Pharma
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study in Parkinson’s Disease Patients With Moderate to Severe Dyskinesia to Assess the Efficacy and Safety/Tolerability of Two Dose Co...
    Medical condition: Parkinson’s Disease Patients With Moderate to Severe Dyskinesia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Restarted) IT (Ongoing) SK (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-006991-18 Sponsor Protocol Number: 2020/0423/HP Start Date*: 2023-04-21
    Sponsor Name:CHU de Rouen
    Full Title: Postoperative anti-infective strategy following pancreaticoduodenectomy in patients with preoperative biliary stent
    Medical condition: Patients with preoperative biliary stent treated by pancreaticoduodenectomy
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10073866 Tumor of hepatopancreatic ampulla LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-002285-23 Sponsor Protocol Number: POETIG Start Date*: 2017-01-18
    Sponsor Name:Universitaetsklinikum Essen
    Full Title: Phase 2 trial of ponatinib in patients with metastatic and/or unresectable gastrointestinal stromal tumor (GIST) following failure or intolerance of prior therapy with imatinib (POETIG trial – POna...
    Medical condition: gastrointestinal stromal tumor (GIST)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10051066 Gastrointestinal stromal tumour PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-024202-34 Sponsor Protocol Number: 24122010 Start Date*: 2014-04-24
    Sponsor Name:UNIVERSITÄTSMEDIZIN GÖTTINGEN, GEORG-AUGUST-UNIVERSITÄT,Klinik für Kinder- und Jugendpsychiatrie/Psychotherapie
    Full Title: Effect of oxytocin on therapy results of a group based social skill training in adolescents with Autism Spectrum Disorder
    Medical condition: high-functioning autismus spectrum disorders: autistic disorder (F84.0), Asperger syndrome (F84.5), atypical autism (F84.1)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004873 10021737 Infantile autism LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-003558-17 Sponsor Protocol Number: TRx-237-039 Start Date*: 2018-02-25
    Sponsor Name:TauRx Therapeutics Ltd
    Full Title: Randomized, Double-Blind, Placebo-Controlled, Three-Arm, 12-Month, Safety and Efficacy Study of Hydromethylthionine Mesylate (LMTM) Monotherapy in Subjects with Alzheimer's Disease Followed by a 12...
    Medical condition: Alzheimer’s Disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10001896 Alzheimer's disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) BE (Completed) PL (Completed) ES (Ongoing) FR (Completed) IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2023-000035-74 Sponsor Protocol Number: 1.1_27.02.2023 Start Date*: 2023-03-05
    Sponsor Name:Medical University Vienna
    Full Title: Pharmacodynamics of Liposomal Bupivacaine for Peripheral Nerve Blockade: A Randomized, Triple-blinded, Cross Over Study in Volunteers
    Medical condition: To evaluate the pharmacodynamic effects of perineural administered liposomal bupivacaine on nerve block characteristics
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-002481-32 Sponsor Protocol Number: InflamAD Start Date*: 2023-04-11
    Sponsor Name:Amsterdam UMC VUmc
    Full Title: Imaging inflammation in Alzheimer's Disease
    Medical condition: Amyloid-beta positive individuals across the Alzheimer's disease continuum and amyloid-beta negative individuals without cognitive complaints
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001022-57 Sponsor Protocol Number: Qutenza-FM-20 Start Date*: 2020-12-18
    Sponsor Name:Wojciech Zbigniew Pawlak
    Full Title: The effect of Qutenza application in patients with post-operative neuropathic pain: A double-blind, randomized, controlled pilot study
    Medical condition: Post-operative neuropathic pain
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004852 10054095 Neuropathic pain LLT
    20.0 100000004852 10077974 Peripheral neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-006239-44 Sponsor Protocol Number: NL37603.042.11 Start Date*: 2012-10-02
    Sponsor Name:Dutch Childhood Oncology Group
    Full Title: An international collaborative study to discontinue Imatinib/Glivec® in pediatric CML patients with sustained complete molecular response (STOPIMAPED)
    Medical condition: Chronic Myeloid Leukemia pediatric patients treated with Imatinib having achieved and maintained complete molecular remission for at least 2 years.
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-001612-11 Sponsor Protocol Number: 3005032 Start Date*: 2018-01-11
    Sponsor Name:Region Hovedstaden
    Full Title: A COMPARISON OF DEXMEDETOMIDINE VS PLACEBO AFFECT ON SLEEP-QUALLITY IN MECHANICAL VENTILATED CRITICAL ILL PATIENTS
    Medical condition: Sleeping problems in mechanical ventilated critical ill patients in ICU
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022891 - Investigations 10053319 Sleep study PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2014-004278-40 Sponsor Protocol Number: CA180-597 Start Date*: 2015-11-09
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: Continuing Treatment for Subjects Who Have Participated on a Prior Protocol Investigating Dasatinib
    Medical condition: Newly Diagnosed Chronic Phase Philadelphia Chromosome Positive Chronic Myeloid Leukemia / Castration-Resistant Prostate Cancer
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: View results
    EudraCT Number: 2020-000148-76 Sponsor Protocol Number: 3.0 Start Date*: 2021-08-04
    Sponsor Name:Stockholm Health Care Services
    Full Title: Effects of Montelukast on neuroinflammation in Parkinson's Disease. An open-label single-center trial.
    Medical condition: Parkinson's disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2022-003866-19 Sponsor Protocol Number: 83336 Start Date*: 2023-05-01
    Sponsor Name:Amsterdam UMC location AMC
    Full Title: The effect of low-dose rhythmic 17-β-estradiol administration on bone turnover in postmenopausal women
    Medical condition: Osteoporosis prevention
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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