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Clinical trials for Oral Cavity

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    315 result(s) found for: Oral Cavity. Displaying page 1 of 16.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2007-007034-18 Sponsor Protocol Number: DCC Start Date*: 2009-01-26
    Sponsor Name:Charité Universitätsmedizin Berlin - CVK
    Full Title: Phase II-Studie zur Erfassung der Effektivität einer wöchentlich verabreichten Docetaxel-Carboplatin/Cisplatin-Cetuximab-Kombination (DCC) bei fortgeschrittenen Plattenepithelkarzinomen des Orophar...
    Medical condition: patients with advanced squamaous cell carcinom on oropharynx or oral cavity
    Disease: Version SOC Term Classification Code Term Level
    12.1 10041857 Squamous cell carcinoma of the oral cavity LLT
    12.1 10031112 Oropharyngeal squamous cell carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-000833-39 Sponsor Protocol Number: 35/04 Start Date*: 2004-10-22
    Sponsor Name:ISTITUTO NAZIONALE PER LA CURA TUMORI
    Full Title: RANDOMIZED STUDY WITH POSTOPERATIVE RADIOTHERAPY AND CONCURRENT LOW DOSE CISPLATIN VS RADIOTHERAPY AND CONCURRENT CISPLATIN + FLUOROURACIL IN OPERATED HIGH RISK SQUAMOUS CELL CARCINOMA OF T...
    Medical condition: Head and neck cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061325 Oral neoplasm LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-022425-15 Sponsor Protocol Number: MK07 Start Date*: 2011-02-28
    Sponsor Name:Universitätsklinikum Heidelberg
    Full Title: ACCEPT - (ACC, Erbitux® and particle therapy) - Combined treatment of adenoid cystic carcinoma with cetuximab and IMRT plus C12 heavy ion boost (Phase I/II feasibility study)
    Medical condition: Adenoid-cystic carcinoma
    Disease: Version SOC Term Classification Code Term Level
    12.1 10001220 Adenoid cystic carcinoma of the oral cavity LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-005015-13 Sponsor Protocol Number: C0947 Start Date*: 2018-05-18
    Sponsor Name:The Clatterbridge Cancer Centre NHS Foundation Trust
    Full Title: NICO - CA209-891: Neoadjuvant and adjuvant nivolumab as Immune Checkpoint inhibition in Oral cavity cancer
    Medical condition: Locally advanced squamous cell carcinoma of the oral cavity
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10041857 Squamous cell carcinoma of the oral cavity PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2010-018363-42 Sponsor Protocol Number: DOXERT1 Start Date*: 2010-09-15
    Sponsor Name:ISTITUTO NAZIONALE PER LO STUDIO E LA CURA DEI TUMORI - FONDAZIONE "G. PASCALE"
    Full Title: A phase II dose finding study of induction cisplatin, docetaxel and escalating doses of capecitabine followed by concurrent cetuximab and radiotherapy in locally advanced inoperable head and neck s...
    Medical condition: locally advanced inoperable head and neck squamous cell carcinoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10026660 HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-000373-21 Sponsor Protocol Number: IRX-22015A Start Date*: 2016-10-27
    Sponsor Name:IRX Therapeutics, Inc.
    Full Title: A Randomized Phase 2 Trial of Neoadjuvant and Adjuvant Therapy with the IRX-2 Regimen in Patients with Newly Diagnosed Stage II, III or IVA Squamous Cell Carcinoma of the Oral Cavity
    Medical condition: Newly Diagnosed Stage II, III or IVA Squamous Cell Carcinoma of the Oral Cavity.
    Disease: Version SOC Term Classification Code Term Level
    19.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10041857 Squamous cell carcinoma of the oral cavity PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended) HU (Prematurely Ended) IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2022-001361-12 Sponsor Protocol Number: FG001-CT-003 Start Date*: 2022-08-25
    Sponsor Name:FluoGuide A/S
    Full Title: An open-label, non-randomized, single center, single dose, exploratory phase II trial of FG001 (an imaging agent) for localization of oral and oropharyngeal squamous cell carcinoma
    Medical condition: Oral and oropharyngeal squamous cell carcinoma
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10041857 Squamous cell carcinoma of the oral cavity PT
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10031112 Oropharyngeal squamous cell carcinoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2013-003622-86 Sponsor Protocol Number: CA209-141 Start Date*: 2014-06-05
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: An Open Label, Randomized Phase 3 Clinical Trial of Nivolumab vs Therapy of Investigator's Choice in Recurrent or Metastatic Platinum-refractory Squamous Cell Carcinoma of the Head and Neck (SCCHN)
    Medical condition: Squamous cell carcinoma of the head and neck
    Disease: Version SOC Term Classification Code Term Level
    16.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10066471 Squamous cell carcinoma of pharynx PT
    16.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10041857 Squamous cell carcinoma of the oral cavity PT
    16.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10023856 Laryngeal squamous cell carcinoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) GB (Completed) ES (Completed) DE (Completed) NL (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2005-003484-23 Sponsor Protocol Number: Paccis-RCT_2005 Start Date*: 2010-04-14
    Sponsor Name:Universitätsklinikum Erlangen, Strahlenklinik insoweit handelnd für den Freistaat Bayern
    Full Title: Randomised phase-III-trial of simultaneous radiochemotherapy (RCT) of locally advanced head and neck cancer in the stages III and IV A-B: Comparing dose reduced RCT (63.6 Gy) with Paclitaxel/Cispla...
    Medical condition: Head and Neck cancer, Stage III-IV A-B
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004864 10026518 Malignant neoplasm of supraglottis stage III LLT
    18.0 100000004864 10026185 Malignant neoplasm of oropharynx, unspecified LLT
    18.0 100000004864 10041862 Squamous cell carcinoma of the oral cavity stage III LLT
    18.0 100000004864 10041863 Squamous cell carcinoma of the oral cavity stage IV LLT
    18.0 100000004864 10041855 Squamous cell carcinoma of the hypopharynx stage IV LLT
    18.0 100000004864 10041854 Squamous cell carcinoma of the hypopharynx stage III LLT
    18.0 100000004864 10026519 Malignant neoplasm of supraglottis stage IV LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2013-002190-22 Sponsor Protocol Number: Phlogosol_2013/01 Start Date*: 2014-03-26
    Sponsor Name:PannonPharma Ltd.
    Full Title: Therapeutic clinical trial of three types of “Phlogosol concentrate for gargle” products, comparing their efficacy in reducing different inflammations of the oral cavity. (Changing the active ing...
    Medical condition: Cold with sore throat, acute stomatitis, chronic pharyngitis acute tonsillitis, acute laryngitis, herpes stomatitis, superficial glossitis, acute and chronic gingivitis, ulcerative gingivitis, paro...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2016-001256-22 Sponsor Protocol Number: GL0817-01 Start Date*: 2017-01-31
    Sponsor Name:Gliknik Inc
    Full Title: A Phase 2 Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Determine the Safety and Efficacy of GL-0817 (with Cyclophosphamide) for the Prevention of Recurrence in HLA-A2+ Patients wi...
    Medical condition: Prevention of Recurrence in HLA-A2+ Patients with High-Risk Squamous Cell Carcinoma of the Oral Cavity
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004856 10026660 Malignant oral cavity neoplasms HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) ES (Prematurely Ended) PL (Prematurely Ended) HU (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-001354-41 Sponsor Protocol Number: UCLONCO08-001 Start Date*: 2008-04-11
    Sponsor Name:Cliniques Universitaires St Luc, Centre du Cancer
    Full Title: Neoadjuvant cetuximab monotherapy followed by surgery in squamous cell carcinoma of head and neck: phase I/II study
    Medical condition: patients with squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx, or larynx newly diagnosed and eligible for surgery.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10041857 Squamous cell carcinoma of the oral cavity LLT
    9.1 10031112 Oropharyngeal squamous cell carcinoma LLT
    9.1 10021042 Hypopharyngeal cancer LLT
    9.1 10023856 Laryngeal squamous cell carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2010-021658-21 Sponsor Protocol Number: HN10/01 Start Date*: 2010-09-27
    Sponsor Name:ISTITUTO NAZIONALE PER LA CURA TUMORI
    Full Title: Phase II study of preoperative TPF chemotherapy in locally advanced resectable oral cavity squamous cell cancer in order to improve the rate of pathological complete response
    Medical condition: oral cavity cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-003524-11 Sponsor Protocol Number: CIG025A2426 Start Date*: 2006-09-19
    Sponsor Name:University Hospital Gent
    Full Title: Clinical and biological effects of Anti-IgE (Omalizumab) in patients with bilateral nasal polyposis and asthma
    Medical condition: patients with nasal polyps and comorbid asthma
    Disease: Version SOC Term Classification Code Term Level
    8.1 10028756 Nasal polyps LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-005644-17 Sponsor Protocol Number: Nosponsor1 Start Date*: 2008-11-18
    Sponsor Name:Hytönen Maija
    Full Title: Nenäpolyyppien hoito montelukastilla Montelukast treatment in nasal polyps
    Medical condition: Aineistoon otetaan HYKS Korvaklinikalla hoidossa olevia aikuisia (> 18 v) ja hankalaa nenän polyyp-pitautia sairastavia potilaita (inkluusiokriteerit, Liite 3): 1) joilla on vähintään gradus 2/2 po...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028756 Nasal polyps LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-003101-42 Sponsor Protocol Number: EFC14146 Start Date*: 2016-11-18
    Sponsor Name:SANOFI-AVENTIS RECHERCHE ET DEVELOPPEMENT
    Full Title: A Randomized, 24-Week Treatment, Double-blind, Placebo-controlled Efficacy and Safety Study of Dupilumab Every Other Week, in Patients with Bilateral Nasal Polyposis on a Background Therapy with In...
    Medical condition: nasal polyps
    Disease: Version SOC Term Classification Code Term Level
    19.0 10038738 - Respiratory, thoracic and mediastinal disorders 10028756 Nasal polyps PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) HU (Completed) DE (Completed) NL (Completed) CZ (Completed) FR (Completed) PL (Completed) BG (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-000838-21 Sponsor Protocol Number: 34/04 Start Date*: 2004-10-22
    Sponsor Name:ISTITUTO NAZIONALE PER LA CURA TUMORI
    Full Title: RANDOMIZED STUDY OF RADIOTHERAPY WITH CONCOMITANT BOOST (RTcb) AND CONCURRENT LOW DOSE CISPLATIN VS RTcb AND CISPLATIN + FLUOROURACIL IN ADVANCED HNSCC
    Medical condition: Head and neck cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030969 Oral cavity neoplasms NEC HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-002082-65 Sponsor Protocol Number: 2016-002082-65 Start Date*: 2016-10-26
    Sponsor Name:Andreas Kjaer
    Full Title: Phase II trial: uPAR-PET/CT for prognostication in head- and neck cancer
    Medical condition: Head and neck cancer
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004856 10026660 Malignant oral cavity neoplasms HLT
    19.0 100000004864 10028801 Oropharyngeal, nasopharyngeal and tonsillar neoplasms malignant and unspecified HLT
    19.0 100000004864 10023826 Laryngeal neoplasms malignant HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-003589-15 Sponsor Protocol Number: ECT-HN Start Date*: 2019-01-24
    Sponsor Name:ISTITUTO NAZIONALE TUMORI - IRCCS FONDAZIONE PASCALE
    Full Title: Electrochemotherapy as a first line treatment in recurrent squamous cell carcinoma of the oral cavity and oropharynx: a randomized controlled trial
    Medical condition: carcinoma of the oral cavity and oropharynx
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2015-001314-10 Sponsor Protocol Number: EFC14280 Start Date*: 2016-11-29
    Sponsor Name:SANOFI-AVENTIS RECHERCHE ET DEVELOPPEMENT
    Full Title: A Randomized, Double-blind, 52-week, Placebo Controlled Efficacy and Safety Study of Dupilumab, in Patients with Bilateral Nasal Polyposis on a Background Therapy with Intranasal Corticosteroids
    Medical condition: Bilateral nasal polyposis
    Disease: Version SOC Term Classification Code Term Level
    19.0 10038738 - Respiratory, thoracic and mediastinal disorders 10028756 Nasal polyps PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) PT (Completed) ES (Completed) BE (Completed)
    Trial results: View results
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