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The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44393   clinical trials with a EudraCT protocol, of which   7405   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    39,320 result(s) found for: 1. Displaying page 1,680 of 1,966.
    «« First « Previous 1676  1677  1678  1679  1680  1681  1682  1683  1684  Next» Last»»
    EudraCT Number: 2011-003087-70 Sponsor Protocol Number: PM1125 Start Date*: 2011-12-02
    Sponsor Name:Polichem SA
    Full Title: Randomized, open-label, controlled study on the efficacy of Ciclopoli® (ciclopirox 8% nail lacquer) versus Loceryl® (amorolfine 5% nail lacquer) on the culture conversion to negative in patients w...
    Medical condition: distal subungual onychomycosis without lunula involvement due to fungal nail pathogens (dermatophytes, white yeasts and/or Scopulariopsis spp. and/or Fusarium spp.) affecting at least one big toenail
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LV (Completed)
    Trial results: View results
    EudraCT Number: 2013-000389-12 Sponsor Protocol Number: 3.0 Start Date*: 2013-09-11
    Sponsor Name:Cardiff University
    Full Title: ANti-psychotic Drug REduction in primary care for Adults with Learning Disabilities (ANDREA-LD): A Randomised Double-blind Placebo Controlled Trial
    Medical condition: Aggression and challenging behaviour in adults with learning disabilities
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-000364-16 Sponsor Protocol Number: CELYVIR Start Date*: 2011-02-07
    Sponsor Name:FUNDACION PARA LA INVESTIGACION BIOMEDICA HOSPITAL UNIVERSITARIO NIÑO JESUS
    Full Title: Ensayo clínico abierto de fase I para evaluar la eficacia y seguridad del tratamiento con células mesenquimales autólogas infectadas con un nuevo adenovirus oncolítico en el tratamiento de paciente...
    Medical condition: Niños con tumor sólido refractario o recidivante a dos o más líneas de tratamiento estándar de los siguientes diagnósticos histológicos: neuroblastoma estadio IV, sarcoma de Ewing con metástasis ós...
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-005208-14 Sponsor Protocol Number: R17548 Start Date*: 2012-06-18
    Sponsor Name:Norfolk and Norwich University Hospitals NHS Foundation Trust
    Full Title: Innovative Gel Aid for Administering Tablets to Stroke and Other Dysphagic Patients
    Medical condition: Healthy volunteers will be used in the study however the gel device being investigated has been developed with the aim of aiding swallowing in stroke and other dysphagic patients.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10017947 - Gastrointestinal disorders 10013950 Dysphagia PT
    Population Age: Adults Gender: Male
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-015730-30 Sponsor Protocol Number: 2009-23 Start Date*: 2009-10-13
    Sponsor Name:ASSISTANCE PUBLIQUE HOPITAUX DE MARSEILLE
    Full Title: OPTIMISATION DE L’EVALUATION DE LA FONCTION SURRENALIENNE APRES ARRET D’UNE CORTICOTHERAPIE PROLONGEE
    Medical condition: L’ insuffisance surrénale post-corticothérapie
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-004269-15 Sponsor Protocol Number: D-13-01 Start Date*: 2014-03-17
    Sponsor Name:Insituto Aragonés de Ciencias de la Salud
    Full Title: Aspirin and colorectal cancer prevention. Exploring the platelet hypothesis of its mechanism of action
    Medical condition: We will perform this clinical study to address the hypothesis that low-dose aspirin given once daily is acting primarily by selectively acetylating platelet COX-1 and suppressing its activity throu...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-001834-16 Sponsor Protocol Number: AD101_01 Start Date*: 2014-01-10
    Sponsor Name:ISTITUTI FISIOTERAPICI OSPITALIERI
    Full Title: EVALUATION OF SEIZURE CONTROL AND QUALITY OF LIFE IN PATIENTS WITH BRAIN TUMOR RELATED EPILEPSY TREATED WITH LACOSAMIDE AS ADD-ON THERAPY: A PROSPECTIVE EXPLORATIVE STUDY
    Medical condition: PATIENTS WITH BRAIN TUMOR RELATED EPILEPSY
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004852 10068330 Symptomatic epilepsy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-003547-39 Sponsor Protocol Number: 46077 Start Date*: 2013-10-15
    Sponsor Name:Isala Klinieken
    Full Title: Dexmedetomidine vs. clonidine in delirious intensive care patients: a randomised open-label trial
    Medical condition: (ICU- associated) Delirium
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004873 10012226 Delirium, cause unknown LLT
    16.0 100000004873 10071315 Mixed delirium LLT
    16.0 100000004873 10071313 Hypoactive delirium LLT
    16.0 100000004873 10071314 Hyperactive delirium LLT
    16.0 100000004873 10012220 Delirium due to a general medical condition LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-001743-31 Sponsor Protocol Number: NL43882.029.13 Start Date*: 2013-08-06
    Sponsor Name:VU University Medical Center
    Full Title: The cardiovascular effects of hyperoxia during and shortly after CABG surgery
    Medical condition: During and after coronary artery bypass graft operation we will investigate the cardiovascular effects of hyperoxia on blood pressure, cardiac function, microcirculation and ischemia/reperfusion.
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004866 10051615 Atherosclerotic cardiovascular disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-005745-20 Sponsor Protocol Number: IPR/26 Start Date*: 2013-03-24
    Sponsor Name:MolMed S.p.A.
    Full Title: NGR018: Randomized phase II study of NGR-hTNF plus an anthracycline versus an anthracycline alone in platinum-resistant ovarian cancer
    Medical condition: Advanced or metastatic platinum-resistant ovarian cancer patients
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2015-005700-28 Sponsor Protocol Number: AIDA_104599 Start Date*: 2016-04-20
    Sponsor Name:Erasmus MC
    Full Title: An evaluation of the effectivity of the current treatment of uncomplicated urinary tract infections with fosfomycin.
    Medical condition: Healthy volunteers
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004862 10024981 Lower urinary tract infection LLT
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-005536-17 Sponsor Protocol Number: IIBSP-CIP-2013-166 Start Date*: 2014-08-18
    Sponsor Name:Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau ? IIB Sant Pau
    Full Title: Multicenter, randomized and double-blinded clinical trial on the use of antibiotic prophylaxis for EUS guided FNA of pancreatic cystic lesions
    Medical condition: Pancreatic cystic lesions
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-001959-24 Sponsor Protocol Number: BoTN-Study Start Date*: 2014-08-26
    Sponsor Name:University Hospital Essen
    Full Title: BoTN: Onabotulinumtoxin A for the treatment of trigeminal neuralgia: Efficacy, safety and neurophysiological alterations under therapy – a prospective, controlled trial
    Medical condition: Trigeminal neuralgia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-004797-33 Sponsor Protocol Number: Obstetrics1.0 Start Date*: 2018-06-13
    Sponsor Name:CHU Tivoli
    Full Title: The efficacy of continuous ropivacaine wound infusion after cesarean delivery in pain management.
    Medical condition: Poor postoperative pain control leads to decreased satisfaction with care, prolonged recovery time and increased use of health care resources. Despite their efficacy, opioids are associated with na...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-005092-24 Sponsor Protocol Number: FSJD-PIOSPIMET-2015 Start Date*: 2016-01-22
    Sponsor Name:FUNDACIÓ SANT JOAN DE DÉU
    Full Title: A prospective, open-label, randomized, two-armed clinical trial to evaluate the efficacy and safety of a combination of ethinyl-estradiol and levonorgestrel versus a low-dose combination of pioglit...
    Medical condition: ovarian hyperandrogenism with hyperinsulinaemia
    Disease:
    Population Age: Adolescents, Under 18 Gender: Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-003541-17 Sponsor Protocol Number: FIMHCSBR-2017 Start Date*: 2018-10-24
    Sponsor Name:FIMABIS Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud [...]
    1. FIMABIS Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
    2. APES Costa del Sol (Agencia Pública Empresarial Sanitaria)
    Full Title: Neuropsiquiatric Evolution After Introduction of Raltegravir QD in substitution of dolutegravir: NEAR QD Study
    Medical condition: Human Inmunodeficiency Virus Infection (HIV)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-004184-36 Sponsor Protocol Number: UKER-AN-HS-01 Start Date*: 2016-01-05
    Sponsor Name:Universitätsklinikum Erlangen
    Full Title: Prospective, randomised, double-blind, placebo-controlled, single centre phase IIa clinical trial to investigate the safety and tolerability as well as the impact of a substitution of sexual hormon...
    Medical condition: Substitution of sexual hormones in adult females with anorexia nervosa
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004865 10063915 Substitution therapy LLT
    Population Age: Adults Gender: Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-003338-15 Sponsor Protocol Number: RBHP2014ELJEZI Start Date*: 2014-12-01
    Sponsor Name:CHU de Clermont-Ferrand
    Full Title: Role of Nitric Oxide (NO) in pre-oxygenation before anesthetic induction in patients with Pulmonary Hypertension (PH) in cardiac surgery. Feasibility study.
    Medical condition: - Cardiac surgery open heart - Pulmonary Hypertension with PAPs> 40 mmHg secondary to left heart disease or COPD (class 2 or 3), diagnosed by preoperative right heart catheterization or transthora...
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004863 10017501 Functional disturbances following cardiac surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001474-41 Sponsor Protocol Number: 17-014 Start Date*: 2017-07-26
    Sponsor Name:CHU CAEN
    Full Title: Bénéfices de la perfusion continue de lidocaïne intraveineuse en chirurgie bariatrique : une étude randomisée prospective contre placebo
    Medical condition: Patients obèses éligibles et programmés pour une chirurgie bariatrique
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10068900 Bariatric surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-003427-38 Sponsor Protocol Number: HGT-GCB-068 Start Date*: 2016-04-07
    Sponsor Name:Shire Human Genetic Therapies
    Full Title: A Multi-center, Open-label, Efficacy and Safety Study of Velaglucerase Alfa Enzyme Replacement Therapy in Children and Adolescents With Type 3 Gaucher Disease
    Medical condition: Type 3 Gaucher disease
    Disease: Version SOC Term Classification Code Term Level
    18.1 10010331 - Congenital, familial and genetic disorders 10075697 Gaucher's disease type I PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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