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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,380 result(s) found. Displaying page 1,961 of 2,219.
    EudraCT Number: 2007-002664-10 Sponsor Protocol Number: 75/2007/U/Sper Start Date*: 2007-05-22
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: A Randomised Comparison Between 150 mg/die Clopidogrel Maintenance Dose Versus 75 mg/die in Patients with ST Segment Elevation Acute Myocardial Infarction: Effects on Platelet Aggregation and Infla...
    Medical condition: ST Segment Elevation Acute Myocardial Infarction
    Disease: Version SOC Term Classification Code Term Level
    6.1 10000891 PT
    Population Age: Newborns, Infants and toddlers, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-002688-28 Sponsor Protocol Number: 66/2007/U/Sper Start Date*: 2007-05-22
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: Pilot study on the short-term effects of Sildenafil on hemodynamic response to exercise and exercise capacity in Fontan patients
    Medical condition: congenital heart disease
    Disease: Version SOC Term Classification Code Term Level
    6.1 10045545 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-002934-12 Sponsor Protocol Number: 77/2007/U/Sper Start Date*: 2007-06-12
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: MANTEINANCE TREATMENT IN NERD PATIENT. A COMPARATIVE RANDOMIZED OPEN STUDY BETWEEN ALGINATE AND MAGALDRATE.
    Medical condition: Gastroesophageal reflux
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038263 Reflux oesophagitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-003275-40 Sponsor Protocol Number: 63/2007/O/Sper Start Date*: 2008-07-29
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: New immunosuppressive treatments to reduce the rate of recurrence of hepatocellular carcinoma after liver transplantation
    Medical condition: Liver transplantation in patients with hepatocellular carcinoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019695 Hepatic neoplasm LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-002300-27 Sponsor Protocol Number: SPON1529-16 Start Date*: 2019-09-13
    Sponsor Name:Cardiff University
    Full Title: Phase 1b/II Trial of Checkpoint Inhibitor (Pembrolizumab an Anti PD-1 Antibody) Plus Standard IMRT in HPV Induced Stage III Squamous Cell Carcinoma of Anus
    Medical condition: Locally advanced (stage IIIA/B, T3/T4, any N,M0) anal cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061424 Anal cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Trial now transitioned) GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2007-003066-18 Sponsor Protocol Number: GESIDA-5406 Start Date*: 2007-12-15
    Sponsor Name:Dr. Miguel Cervero
    Full Title: Estudio piloto, aleatorizado, nacional, multicéntrico, de eficacia inmunológica, comparando un régimen TARGA de tres fármacos (Tenofovir + Emtricitabina + Lopinavir/r) y cuatro fármacos (Tenofovir ...
    Medical condition: Pacientes diagnosticados de infección por VIH con CD4 < 100 células/microlitro, que comienzan por primera vez tratamiento antirretrovial.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-001463-51 Sponsor Protocol Number: NESS-STUDY Start Date*: 2011-07-14
    Sponsor Name:Servicio de Enfermedades Infecciosas. Unidad VIH. Hospital Universitari de Bellvitge
    Full Title: EVALUACIÓN DE LOS NIVELES DE ETRAVIRINA EN PLASMA SEMINAL EN SUJETOS INFECTADOS POR EL VIH
    Medical condition: HIV
    Disease: Version SOC Term Classification Code Term Level
    14.0 10021881 - Infections and infestations 10008922 Chronic infection with HIV LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-001638-12 Sponsor Protocol Number: mRNA-1010-P302 Start Date*: 2022-09-29
    Sponsor Name:ModernaTX, Inc.
    Full Title: A Phase 3, Randomized, Observer-blind, Active-controlled Study to Evaluate the Safety and Efficacy of mRNA-1010 Candidate Seasonal Influenza Vaccine in Adults 50 Years and Older.
    Medical condition: Influenza
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10022000 Influenza PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) DE (Completed) EE (Completed) BG (Completed) DK (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2016-004978-17 Sponsor Protocol Number: FAR-NP-2017-01 Start Date*: 2017-07-27
    Sponsor Name:Hospital Universitari Bellvitge
    Full Title: CLINICAL, RANDOMIZED, DOUBLE LIND CLINICAL TRIAL TO STUDY THE EFFECT OF PARENTERAL SUPPLEMENTATION WITH FISH OIL EMULSION IN THE NUTRITIONAL SUPPORT IN ESOPHAGECTOMIZED PATIENTS
    Medical condition: Esophagectomy due to esophageal neoplasia
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10067473 Immunomodulatory therapy PT
    20.0 10042613 - Surgical and medical procedures 10044107 Total parenteral nutrition LLT
    20.0 10042613 - Surgical and medical procedures 10015460 Esophagectomy LLT
    20.0 10022891 - Investigations 10024587 Lipids PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-003884-30 Sponsor Protocol Number: 117/2007/U/Sper Start Date*: 2008-03-17
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: Open label, non-randomized, phase II study on fractioned cyclophosphamide, vincristine, liposomal doxorubicin or doxorubicin, and dexamethasone (MY HYPER-CVAD) in the treatment of relapsed refracto...
    Medical condition: refractory adult acute lymphoid leukemia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000846 Acute lymphocytic leukaemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-003210-24 Sponsor Protocol Number: DAHHS2V1.0 Start Date*: 2016-01-07
    Sponsor Name:Erasmus MC
    Full Title: Grazoprevir (MK-5172) + Elbasvir (MK-8742) for the treatment of acute hepatitis C genotype 1/4. The Dutch Acute HCV in HIV Study (DAHHS-2)
    Medical condition: Acute Hepatitis C in HIV infected patients
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-001252-41 Sponsor Protocol Number: NA Start Date*: 2022-07-08
    Sponsor Name:CHU de Liège
    Full Title: Preventing postoperative anaemia in total knee arthroplasty and impact of intravenous iron supplementation on postoperative functional recovery : a randomized clinical trial
    Medical condition: Total Knee Arthroplasty
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-005894-77 Sponsor Protocol Number: 107/2007/O/Sper Start Date*: 2007-12-18
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: Phase I/II study with cisplatin and pemetrexed +/- sorafenib in malignant pleural mesothelioma (SoMe study)
    Medical condition: malignant pleural mesothelioma (MPM)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10059518 Pleural mesothelioma malignant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-006220-35 Sponsor Protocol Number: 118/2007/O/Sper Start Date*: 2008-06-03
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: Efficacy of Oral Leukotriene in long term therapy of mild and moderate obstructive sleep apnea syndrome (OSAS) in children.
    Medical condition: obstructive sleep apnea syndrome
    Disease: Version SOC Term Classification Code Term Level
    9.1 10040979 Sleep apnoea syndrome LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-005373-58 Sponsor Protocol Number: 82/2007/O/Sper Start Date*: 2007-09-18
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: EVALUATION OF DIAGNOSTIC ACCURACY OF 68GA-CITRATE PET/CT IN PATIENTS WITH INFLAMMATORY-INFECTIOUS DISEASES.
    Medical condition: Inflammatory disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10005941 Bone and joint infections (excl arthritis) HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-000625-19 Sponsor Protocol Number: 3/2008/U/Sper Start Date*: 2008-04-21
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: The use of human albumin for the treatment of ascites in patients with hepatic cirrhosis: A multicenter, open-label randomized clinical trial.
    Medical condition: ascites in patients with hepatic cirrhosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003445 Ascites LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-002142-50 Sponsor Protocol Number: POPCABG03 Start Date*: 2019-04-09
    Sponsor Name:St. Antonius Hospital
    Full Title: A Randomized, Double-Blind, Placebo-Controlled Trial Investigating The Effect Of Ticagrelor On Saphenous Vein Graft Patency In Patients Undergoing Coronary Artery Bypass Grafting Surgery.
    Medical condition: Coronary artery bypass grafting surgery with the use of one or more saphenous vein grafts.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-001323-64 Sponsor Protocol Number: 7/2008/O/Sper Start Date*: 2008-03-12
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: PHASE III DOUBLE BLIND PLACEBO CONTROLLED RANDOMIZED STUDY ON THE EFFICACY OF URSODEOXYCHOLIC ACID FOR THE TREATMENT OF INTRAHEPATIC CHOLESTASIS OF PREGNANCY
    Medical condition: INTRAHEPATIC CHOLESTASIS OF PREGNANCY
    Disease: Version SOC Term Classification Code Term Level
    9.1 10049055 Cholestasis of pregnancy LLT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-001342-13 Sponsor Protocol Number: 136/2007/O/Sper Start Date*: 2008-02-19
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: Effectiveness on the clinical outcome of an oral enterovaccine (Colifagina) and evaluation of the role of the Astrovirus in the aetiology of the pathology of acute gastroenteritis in children.”
    Medical condition: acute gastroenteritis in children.”
    Disease: Version SOC Term Classification Code Term Level
    9.1 10017893 Gastroenteritis astroviral LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002295-10 Sponsor Protocol Number: 58/2008/U/Sper Start Date*: 2008-10-14
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: Role of immunosuppression with steroids in the outcome of fibrosis due to recurrent hepatitis C virus (HCV) infection after liver transplantation
    Medical condition: fibrosis due to recurrent hepatitis C virus (HCV) infection after liver transplantation
    Disease: Version SOC Term Classification Code Term Level
    9.1 10016648 Fibrosis liver LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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