Clinical trials

The European Union Clinical Trials Register allows you to search for protocol and results information on:

interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC

clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
Clinical Trials Information System (CTIS).

The EU Clinical Trials Register currently displays 44334 clinical trials with a EudraCT protocol, of which 7366 are clinical trials conducted with subjects less than 18 years old. The register also displays information on 18700 older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).

Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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Trials with a EudraCT protocol (44,334)
Paediatric studies in scope of Art45 of the Paediatric Regulation (18,700)

44,334 result(s) found. Displaying page 1,961 of 2,217.

EudraCT Number: 2017-004083-35	Sponsor Protocol Number: 2017-53	Start Date*: 2018-03-28
Sponsor Name:Assistance Publique Hôpitaux de Marseille
Full Title: A double-blind, randomized, multicenter study evaluating 200 mg versus 600 mg of Mifepristone on pain in voluntary abortion by drug prior to 7 SA. DoMy Study
Medical condition: patient of 18 years or more, wishing an abortion with medication before 7 weeks of amenorrhea
Disease:
Population Age: Adults		Gender: Female
Trial protocol: FR (Completed)
Trial results: (No results available)

EudraCT Number: 2021-000170-29

Sponsor Protocol Number: I9X-MC-MTAE

Start Date*: 2021-11-05

Sponsor Name:Eli Lilly and Company

Full Title: Assessment of Safety, Tolerability, and Efficacy of LY3372689 in Early Symptomatic Alzheimer’s Disease

Medical condition: Alzheimer Disease

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	10029205 - Nervous system disorders	10012271	Dementia Alzheimer's type	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: PL (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2020-003497-48

Sponsor Protocol Number: EMPATHY

Start Date*: 2021-11-29

Sponsor Name:Medical University of Warsaw

Full Title: Empagliflozin and dapagliflozin in patients hospitalized for acute decompensated heart failure (EMPATHY) – a phase III trial

Medical condition: acute decompensated heart failure

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	100000004849	10010684	Congestive heart failure	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: PL (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2020-004194-51	Sponsor Protocol Number: 020520	Start Date*: Information not available in EudraCT
Sponsor Name:Medical University of Lodz
Full Title: A prospective, randomized, phase III open-label clinical trial with blinded end-point assessment to evaluate the efficacy and safety of cyclosporine and methotrexate in children and adolescent subj...
Medical condition: Atopic dermatitis
Disease:
Population Age: Children, Adolescents, Under 18		Gender: Male, Female
Trial protocol: PL (Trial now transitioned)
Trial results: (No results available)

EudraCT Number: 2022-003046-13

Sponsor Protocol Number: 2021/ABM/03/00008

Start Date*: 2023-11-27

Sponsor Name:Śląskie Centrum Chorób Serca

Full Title: Sacubitril/Valsartan in PriMAry preventIoN of the cardiotoxicity of systematic breaST canceR trEAtMent. Randomized, multicenter, double-blind, placebo-controlled study.

Medical condition: Heart failure – post-anthracycline cardiomyopathy

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	10007541 - Cardiac disorders	10019279	Heart failure	LLT

Population Age: Adults, Elderly

Gender: Female

Trial protocol: PL (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2005-004810-34	Sponsor Protocol Number: 080971	Start Date*: 2005-11-17
Sponsor Name:Ville Artto
Full Title: PITKITTYNEEN PÄÄNSÄRKYKOHTAUKSEN HOITO HYDROKORTISONILLA, RANDOMOITU JA KAKSOISSOKKOUTETTU TUTKIMUS
Medical condition: Tutkimukseen valitaan Meilahden sairaalan päivystyspoliklinikalle tulevia potilaita, joilla on vaikea, pitkittynyt kotihoidoille resistentti päänsärkyjakso menossa ja jotka tarvitsevat akuuttia kiv...
Disease:
Population Age: Adults		Gender: Male, Female
Trial protocol: FI (Prematurely Ended)
Trial results: (No results available)

EudraCT Number: 2019-004613-14

Sponsor Protocol Number: VERITA_PALG-CLL5

Start Date*: 2021-10-31

Sponsor Name:POLISH ADULT LEUKEMIA GROUP

Full Title: A prospective, multicenter, phase II trial to assess the efficacy and safety of MRD-driven treatment with VEnetoclax and RItuximab combination in previously unTreated pAtients with chronic lymphocy...

Medical condition: Chronic lymphocytic leukemia

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	21.0	100000004864	10008976	Chronic lymphocytic leukemia	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: PL (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2021-000580-78	Sponsor Protocol Number: EMPAtia	Start Date*: 2022-02-02
Sponsor Name:The Children’s Memorial Health Institute
Full Title: "The assessment of effectiveness and safeness of utilizing empagliflozin in the treatment of neutropenia of patients suffering from glycogenolysis type Ib"
Medical condition: neutropenia and / or abnormal neutrophil function in glycogenosis I b
Disease:
Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly		Gender: Male, Female
Trial protocol: PL (Trial now transitioned)
Trial results: (No results available)

EudraCT Number: 2020-003881-38

Sponsor Protocol Number: ESONIA

Start Date*: Information not available in EudraCT

Sponsor Name:Warszawski Uniwersytet Medyczny

Full Title: ESONIA - The evaluation of Efficacy and Safety Of Nebivolol in the treatment of arterial hypertension In Adolescents

Medical condition: Arterial hypertension in adolescents

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	21.1	100000004866	10081425	Arterial hypertension	LLT

Population Age: Adolescents, Under 18

Gender: Male, Female

Trial protocol: PL (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2021-006647-99

Sponsor Protocol Number: 2021/ABM/01/00010

Start Date*: 2022-03-02

Sponsor Name:Medical University of Bialystok

Full Title: Safety Outcomes Post kidney Biopsy – randomized Clinical Evaluation of Efficacy of Desmopressin

Medical condition: Rare and ultra-rare glomerulonephritis

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.1	10038359 - Renal and urinary disorders	10018364	Glomerulonephritis	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: PL (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2017-003565-10

Sponsor Protocol Number: SAKK06/17

Start Date*: 2018-12-03

Sponsor Name:Swiss Group for Clinical Cancer Research

Full Title: Neoadjuvant and adjuvant durvalumab in combination with neoadjuvant chemotherapy in patients with operable urothelial cancer. A multicenter, single-arm phase II Trial.

Medical condition: muscle invasive urothelial cancer (MIUC)

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	100000004864	10064467	Urothelial carcinoma	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Completed)

Trial results: (No results available)

EudraCT Number: 2020-005641-17

Sponsor Protocol Number: 2019/ABM/01/00074

Start Date*: 2021-10-12

Sponsor Name:Medical University of Bialystok

Full Title: Non-commercial clinical trial of statins CAncer preventive and Pleiotropic TherApy IN smokers with chronic obstructive pulmonary disease (COPD) Clinical part: Atorvastatin effect on reduction of CO...

Medical condition: Chronic obstructive pulmonary disease (COPD)

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	27.1	10038738 - Respiratory, thoracic and mediastinal disorders	10009033	Chronic obstructive pulmonary disease	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: PL (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2020-004898-41

Sponsor Protocol Number: NBK241/1/2020

Start Date*: 2021-03-31

Sponsor Name:MEDICAL UNIVERSITY OF GDAŃSK

Full Title: A multicentre, parallel group, randomised, double blind, placebo-controlled, phase II study evaluating the efficacy and safety of reperfusion thrombolytic therapy with intravenous recombinant tissu...

Medical condition: Acute ischemic stroke

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	22.1	10029205 - Nervous system disorders	10061256	Ischaemic stroke	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: PL (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2021-005366-17

Sponsor Protocol Number: 2020/ABM/01/00100

Start Date*: 2022-09-14

Sponsor Name:Medical University of Bialystok

Full Title: Evaluation of METtformin effect on the fertility of patients treated with 131I for THYRoid cancer – METHYR Study.

Medical condition: Thyroid papilare cancer

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	21.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10066474	Thyroid cancer	PT

Population Age: Adults

Gender: Female

Trial protocol: PL (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2021-000442-18

Sponsor Protocol Number: ABM/2020/1/00002

Start Date*: 2021-09-24

Sponsor Name:National Institute of Cardiology

Full Title: Strategy To Optimize PeriproCeduraL AnticOagulation in Structural Transseptal Interventions (STOP CLOT Trial)

Medical condition: Mitral regurgitation Atrial fibrilation Periprocedural anticoagulation strategy in patients treated with MitraClip implantation or Left Atrial Appendage Closure. The patients scheduled for Mitr...

Disease:	Version	SOC Term	Classification Code	Term	Level
	20.0	10007541 - Cardiac disorders	10027718	Mitral regurgitation	LLT
	20.0	10007541 - Cardiac disorders	10003658	Atrial fibrillation	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: PL (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2021-006127-17

Sponsor Protocol Number: CKD/1458/21

Start Date*: 2022-04-09

Sponsor Name:Narodowy Instytut Kardiologii Stefana kardynała Wyszyńskiego- Państwowy Instytut Badawczy

Full Title: Optimal Antiplatelet Treatment to Achieve Stroke Avoidance and Fall in Bleeding Events following Left Atrial Appendage Closure – Chronic Kidney Disease (SAFE LAAC CKD). Comparative Health Effective...

Medical condition: Atrial fibrillation

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	10007541 - Cardiac disorders	10003658	Atrial fibrillation	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: PL (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2020-005302-26

Sponsor Protocol Number: DW.0701.005.2020P

Start Date*: 2023-01-05

Sponsor Name:John Paul II Hospital

Full Title: The effect of sacubitril/valsartan versus ramipril on left ventricular function and remodeling in patients with ischemic heart failure with mid-range ejection fraction

Medical condition: heart failure with moderately reduced ejection fraction (HFmrEF)

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	10007541 - Cardiac disorders	10010684	Congestive heart failure	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: PL (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2022-001287-10

Sponsor Protocol Number: NBK241/2/2022

Start Date*: 2023-09-22

Sponsor Name:Gdański Uniwersytet Medyczny

Full Title: Treatment of acute ischemic stroke due to occlusion of a large vessel by mechanical thrombectomy in patients with unknown onset or not meeting the criteria for CT eligibility (ASPECTS <6) based on ...

Medical condition: acute ischemic stroke caused by occlusion of a large vessel

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	23.1	10029205 - Nervous system disorders	10084836	Malignant ischemic stroke	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: PL (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2005-002484-87	Sponsor Protocol Number: GAST-TaxXel	Start Date*: 2005-07-11
Sponsor Name:Raija Ristamäki
Full Title: Biweekly Taxotere in combination with Xeloda as first-line treatment in patients with advanced gastric cancer
Medical condition: advanced gastric cancer
Disease:
Population Age: Adults, Elderly		Gender: Male, Female
Trial protocol: FI (Completed)
Trial results: (No results available)

EudraCT Number: 2020-004901-29

Sponsor Protocol Number: NBK154/1/2020

Start Date*: 2021-06-01

Sponsor Name:Medical University of Gdańsk

Full Title: The efficacy and safety of Metoprolol as add-on treatment to standard of care in preventing cardiomyopathy in patients with Duchenne Muscular Dystrophy aged 8-17 years. A randomized, double-blind, ...

Medical condition: Duchenne muscular dystrophy Cardiomyopathy Tachycardia

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	27.1	10010331 - Congenital, familial and genetic disorders	10013801	Duchenne muscular dystrophy	PT

Population Age: Children, Adolescents, Under 18

Gender: Male

Trial protocol: PL (Trial now transitioned)

Trial results: (No results available)

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The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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