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Clinical trials for Lumbar spine

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    281 result(s) found for: Lumbar spine. Displaying page 3 of 15.
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    EudraCT Number: 2005-005081-37 Sponsor Protocol Number: 20050141 Start Date*: 2006-06-12
    Sponsor Name:Amgen Inc
    Full Title: A Randomized, Double-Blind Study to Compare the Efficacy of Treatment with Denosumab versus Alendronate Sodium in Postmenopausal Women with Low Bone Mineral Density
    Medical condition: Postmenopausal osteoporosis /osteopenia
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed) BE (Completed) ES (Completed) DE (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2007-001417-41 Sponsor Protocol Number: Breivik vs. Narop Start Date*: 2007-08-10
    Sponsor Name:Stockholm Spine Center
    Full Title: Postoperative epidural analgesia with Breivik's mixture (bupivacain, fentanyl, epinephrine) compared to Narop (rupivacain) combined with oral oxycodon after posterior lumbar fusion.
    Medical condition: Postoperative analgesia in patients undergoing spine surgery, mainly spinal fusions in the lumbar spine.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050505 Spinal fusion surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002693-35 Sponsor Protocol Number: B3D-EW-GHDK Start Date*: 2008-11-21
    Sponsor Name:Eli Lilly and Company Ltd
    Full Title: Comparison of the Effects of Teriparatide with those of Risedronate on Lumbar Spine Bone Mineral Density in Men and Postmenopausal Women with Low Bone Mass and a Recent Pertrochanteric Hip Fracture
    Medical condition: Postmenopausal Women and Men with Low Bone Mass and a Recent Pertrochanteric Fracture
    Disease: Version SOC Term Classification Code Term Level
    17.1 10028395 - Musculoskeletal and connective tissue disorders 10031282 Osteoporosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) DE (Completed) GB (Completed) ES (Completed) IT (Completed) GR (Completed) SE (Completed) AT (Completed) FR (Completed) CZ (Completed) IE (Completed) FI (Completed) NO (Completed)
    Trial results: View results
    EudraCT Number: 2010-019263-11 Sponsor Protocol Number: LTS11298 Start Date*: 2010-07-08
    Sponsor Name:sanofi-aventis Recherche & Développement
    Full Title: A multicenter uncontrolled extension study evaluating the long term safety and efficacy of SAR153191 in patients with Ankylosing Spondylitis (AS)
    Medical condition: Ankylosing Spondylitis
    Disease: Version SOC Term Classification Code Term Level
    12.1 10002556 Ankylosing spondylitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Prematurely Ended) AT (Prematurely Ended) CZ (Prematurely Ended) ES (Completed) HU (Prematurely Ended) LT (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2008-005696-10 Sponsor Protocol Number: CHUBX 2008/21 Start Date*: 2008-10-22
    Sponsor Name:CHU de Bordeaux
    Full Title: Evaluation de l’efficacité de l’infiltration continue d’anesthésiques locaux par un cathéter pariétal paravertébral pour l’analgésie postopératoire après arthrodèse lombaire
    Medical condition: Rachis lombaire dégénératif avec indication d'arthrodèse lombaire par voie postérieure de un à trois niveaux.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10025006 Lumbar spine degeneration LLT
    Population Age: Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-005551-32 Sponsor Protocol Number: 20110174 Start Date*: 2014-06-16
    Sponsor Name:Amgen, Inc.
    Full Title: A Multicenter, Randomized, Double blind, Placebo controlled Study to Compare the Efficacy and Safety of Romosozumab With Placebo in Men With Osteoporosis
    Medical condition: male osteoporosis
    Disease: Version SOC Term Classification Code Term Level
    17.0 10028395 - Musculoskeletal and connective tissue disorders 10031282 Osteoporosis PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: CZ (Completed) BE (Completed) DK (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2009-010205-37 Sponsor Protocol Number: 20080098 Start Date*: 2009-10-28
    Sponsor Name:Amgen Inc
    Full Title: A Multicenter, Randomized, Double-Blind, Placebo Controlled Study to Compare the Efficacy and Safety of Denosumab versus Placebo in Males with Low Bone Mineral Density
    Medical condition: Male Osteoporosis
    Disease: Version SOC Term Classification Code Term Level
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10031282 Osteoporosis PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: SE (Completed) BE (Completed) FR (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2017-000860-14 Sponsor Protocol Number: GR-OG-279239-03 Start Date*: 2018-02-27
    Sponsor Name:Genera Research Ltd
    Full Title: Patient and evaluator blinded non-inferiority study on safety, tolerability and lumbar fusion efficacy of a single administration of Osteogrow (rhBMP6 in autologous blood coagulum (ABC) carrier) in...
    Medical condition: Lumbar spine single segment destabilization caused by degenerative disc disease
    Disease: Version SOC Term Classification Code Term Level
    21.1 10042613 - Surgical and medical procedures 10050505 Spinal fusion surgery PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-001279-19 Sponsor Protocol Number: 20120187 Start Date*: 2014-03-26
    Sponsor Name:Amgen, Inc
    Full Title: A Multicenter, Double-blind, Randomized Study to Assess the Efficacy and Safety of Denosumab Produced by Two Different Processes in Postmenopausal Women With Osteoporosis
    Medical condition: Post Menospausal Osteoporosis
    Disease: Version SOC Term Classification Code Term Level
    16.1 10028395 - Musculoskeletal and connective tissue disorders 10031285 Osteoporosis postmenopausal PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: CZ (Completed) PL (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2013-003359-39 Sponsor Protocol Number: ZEST Start Date*: 2014-01-14
    Sponsor Name:Fundació Clínic per a la Recerca Biomèdica
    Full Title: Bisphosphonate Therapy with Zoledronic acid or Tenofovir Switching to Improve Low Bone Mineral Density in HIV-Infected Adults
    Medical condition: low bone mineral density - HIV
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004862 10068341 HIV-1 infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004796-11 Sponsor Protocol Number: CZOL446GDE24 Start Date*: 2007-08-14
    Sponsor Name:Klinikum Augsburg
    Full Title: An Open-Label, Non-Randomized, Single center Study to Evaluate the Use of Zoledronic Acid in the Prevention of Cancer Treatment-Related Bone Loss in Postmenopausal Women with ER+ and/or PgR+ Breast...
    Medical condition: Prevention of cancer treatment-related bone loss in postmenopausal women with resected stage I-IIIa hormone receptor positive breast cancer, who will receive letrozole as adjuvant therapy.
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-003888-71 Sponsor Protocol Number: CFEM345DDE09 Start Date*: 2005-07-20
    Sponsor Name:Novartis Pharma GmbH
    Full Title: An open phase III trial with Letrozole (Femara®) alone or in combination with Zoledronic acid (Zometa®) as extended adjuvant treatment of postmenopausal patients with primary breast cancer
    Medical condition: prevention of tumortherapy-induced bone loss
    Disease: Version SOC Term Classification Code Term Level
    8.0 10049470 LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-000635-94 Sponsor Protocol Number: DEM100175 Start Date*: 2006-05-11
    Sponsor Name:GlaxoSmithKline Research & Development
    Full Title: A Phase II, randomized, double-blind, parallel group study to examine bone quality and bone mineral density changes following treatment with SB-462795 (40mg, 80mg, 120mg or 160mg), alendronate or p...
    Medical condition: Osteoporosis
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-002476-24 Sponsor Protocol Number: EP-DICLO-TIO/F-01-2015 Start Date*: 2015-10-13
    Sponsor Name:Epifarma S.r.l.
    Full Title: Randomized, double-blind, parallel-groups, active-controlled trial to evaluate the efficacy of a fixed combination of diclofenac 75 mg + thiocolchicoside 4 mg as solution for injection, in improvin...
    Medical condition: low back pain
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004859 10024891 Low back pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-001548-60 Sponsor Protocol Number: MA17903 Start Date*: 2004-08-02
    Sponsor Name:F. Hoffmann-La Roche Ltd
    Full Title: Double-blind, partially randomized, parallel group, multicenter study to assess the efficacy and safety of 100 mg and 150 mg monthly oral ibandronate in women with postmenopausal osteoporosis havin...
    Medical condition: Long term study in women with postmenopausal osteoporosis.
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2006-000011-15 Sponsor Protocol Number: ML20088 Start Date*: 2006-04-05
    Sponsor Name:Roche Oy
    Full Title: A randomized, double-blind, placebo-controlled study to investigate the efficacy and safety of once monthly inbandronate in the prevention of glucocorticoid-induced osteoporosis in postmenopausal w...
    Medical condition: hPrevention of glucocorticoid-induced osteoporosis in postmenopausal women diagnosing any inflammatory rheumatoid disease polymyalgia rheumatica
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2004-000811-24 Sponsor Protocol Number: 308260 Start Date*: 2004-11-19
    Sponsor Name:Schering AG
    Full Title: Multicenter, double-blind, randomized, pleacebo-controlled study to evaluate the oral low-dose estradiol preparations SH T 04170 E (100 µg estradiol) and SH T 04170 F (190 µg estradiol) in postmeno...
    Medical condition: postmenopausal women with high risk for osteoporosis
    Disease: Version SOC Term Classification Code Term Level
    7.0 10050213 LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2008-005991-28 Sponsor Protocol Number: 20060326 Start Date*: 2009-06-26
    Sponsor Name:Amgen Inc
    Full Title: A Randomized, Placebo-controlled, Multi-dose Phase 2 Study to Determine the Efficacy, Safety and Tolerability of AMG 785 in the Treatment of Postmenopausal Women with Low Bone Mineral Density
    Medical condition: Postmenopausal osteoporosis
    Disease: Version SOC Term Classification Code Term Level
    16.1 10028395 - Musculoskeletal and connective tissue disorders 10031285 Osteoporosis postmenopausal PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: AT (Completed) ES (Completed) DK (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2015-001146-29 Sponsor Protocol Number: 1 Start Date*: 2016-01-12
    Sponsor Name:Hospital Central de la Defensa
    Full Title: Selective local anesthesia versus a combined medication injection with corticosteroids in degenerartive spine
    Medical condition: Degenerative spine pain when there are no indications for surgical treatment
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002418-12 Sponsor Protocol Number: CFEM345D2407 Start Date*: 2005-01-25
    Sponsor Name:Novartis Pharma Services AG
    Full Title: An open-label, randomized, multicenter safety study to evaluate the skeletal and lipid profile effects of letrozole and tamoxifen in postmenopausal women with resected, receptor positive early brea...
    Medical condition: Bone loss attributed to cessation of ovarian estrogen production is common in postmenopausal women. In postmenopausal women with breast cancer, treatment with an aromatase inhibitor may further red...
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Completed) GB (Completed)
    Trial results: View results
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