Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Osteoarthritis, Knee AND Pain

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    228 result(s) found for: Osteoarthritis, Knee AND Pain. Displaying page 3 of 12.
    « Previous 1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2015-003230-26 Sponsor Protocol Number: MIV-711-201 Start Date*: 2016-03-23
    Sponsor Name:Medivir AB
    Full Title: A Randomised, Double-blind Placebo-controlled Phase IIa Study to Evaluate Efficacy, Safety and Tolerability of MIV-711 in Knee Joint Osteoarthritis
    Medical condition: Knee Joint Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2011-005254-53 Sponsor Protocol Number: BKOS-03 Start Date*: 2012-05-14
    Sponsor Name:Menarini Ricerche S.p.A
    Full Title: A double-blind, randomised, placebo controlled, sequential ascending dose study, to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of single intra-articular doses of fasi...
    Medical condition: Ostoarthritis of the knee
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-002607-18 Sponsor Protocol Number: 101.04 Start Date*: 2012-08-30
    Sponsor Name:Marius Henriksen
    Full Title: COMBINED INTRA ARTICULAR CORTICOSTEROID AND EXERCISE IN PATIENTS WITH OSTEOARTHRITIS OF THE KNEE: A RANDOMISED TRIAL
    Medical condition: Knee Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10031165 Osteoarthritis knee LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2014-004718-27 Sponsor Protocol Number: INRETRAM3/2014 Start Date*: 2017-01-11
    Sponsor Name:Medical Unviersity of Warsaw
    Full Title: A randomised, multicenter, single-blinded, parallel-group study to assess efficacy, safety and tolerability of the combination of Immediate Release (IR) tramadol with micronized magnesium lactate a...
    Medical condition: Chronic knee and/or hip pain due to Osteoarthritis.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10023476 Knee osteoarthritis LLT
    20.0 100000004859 10020108 Hips osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-000818-37 Sponsor Protocol Number: MTX-071-P03 Start Date*: 2018-06-28
    Sponsor Name:Grünenthal GmbH
    Full Title: A randomized, double-blind, placebo-controlled, single dose phase IIb exploratory study to document the clinical effects and safety of intra-articular injections of Lopain (MTX-071) in patients wit...
    Medical condition: chronic osteoarthritic knee joint pain
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004859 10023476 Knee osteoarthritis LLT
    20.0 100000004859 10003244 Arthritic pains LLT
    20.0 100000004859 10064238 Gonalgia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) SK (Completed) HR (Completed)
    Trial results: View results
    EudraCT Number: 2021-000859-39 Sponsor Protocol Number: EP-104IAR-201 Start Date*: 2021-09-01
    Sponsor Name:Eupraxia Pharmaceuticals Inc.
    Full Title: A Phase 2, Randomized, Double-Blind, Vehicle-Controlled Study Evaluating the Safety, Efficacy and Pharmacokinetics of Single Dose EP-104IAR for 24 Weeks in Patients with Osteoarthritis of the Knee
    Medical condition: Osteoarthritis of the knee
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2009-014516-35 Sponsor Protocol Number: L00023 GE 303 Start Date*: 2009-12-01
    Sponsor Name:PIERRE FABRE MEDICAMENT
    Full Title: EFFICACY AND TOLERABILITY OF CHONDROITIN SULPHATE 1000MG, TWICE DAILY IN PATIENTS WITH SYMPTOMATIC KNEE OSTEOARTHRITIS
    Medical condition: Symptomatic knee osteoarthtitis
    Disease: Version SOC Term Classification Code Term Level
    12.0 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) LT (Completed) BE (Completed) EE (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2006-003485-33 Sponsor Protocol Number: F1J-MC-HMFG Start Date*: 2007-03-21
    Sponsor Name:Eli Lilly and Company Limited
    Full Title: Duloxetine 60 to 120 mg versus Placebo in the Treatment of Patients with Osteoarthritis Knee Pain
    Medical condition: Osteoarthritis Knee Pain
    Disease: Version SOC Term Classification Code Term Level
    8.1 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2015-001981-24 Sponsor Protocol Number: MTX-071-P01 Start Date*: 2016-02-04
    Sponsor Name:Mestex
    Full Title: Lopain (MTX-071 / resiniferatoxin) An open label, dose-escalating phase I/IIa study to determine the safety and clinical effects of intra-articular injections of Lopain (MTX-071) in patients wi...
    Medical condition: Chronic osteoarthritic knee-joint pain
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10023476 Knee osteoarthritis LLT
    20.0 100000004859 10003244 Arthritic pains LLT
    20.0 100000004859 10064238 Gonalgia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2018-001411-71 Sponsor Protocol Number: R475-OA-1815 Start Date*: 2018-12-03
    Sponsor Name:Regeneron Pharmaceuticals, Inc.
    Full Title: Study to Evaluate Synovial Fluid in the Phase 3 Fasinumab Program for Osteoarthritis of the Knee and Hip
    Medical condition: Pain due to osteoarthritis of the knee
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) PL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-002144-27 Sponsor Protocol Number: M12-146 Start Date*: 2012-07-02
    Sponsor Name:Abbott GmbH & Co. KG
    Full Title: A Multicenter, Randomized, Double-Blind, Placebo and Active-Controlled Study Comparing the Safety and Analgesic Efficacy of ABT-110 to Placebo in Subjects with Pain from Osteoarthritis of the Knee
    Medical condition: Pain from Osteoarthritis of the Knee
    Disease: Version SOC Term Classification Code Term Level
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10031165 Osteoarthritis knee LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended) PL (Prematurely Ended) IT (Prematurely Ended) FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-003875-35 Sponsor Protocol Number: GO-ON-01 Start Date*: 2009-03-24
    Sponsor Name:Rottapharm SpA
    Full Title: Comparative study of efficacy and safety of GO-ON and Hyalgan in patients with symptomatic osteoarthritis of the knee.
    Medical condition: Patients with symptomatic osteoarthritis of the knee.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-005398-22 Sponsor Protocol Number: ARACONDRO-001 Start Date*: 2012-10-11
    Sponsor Name:ARAFARMA GROUP, S.A.
    Full Title: A randomized, multicenter, double-blind, double dummy and parallel study to evaluate the efficacy of the combination of Chondroitin sulfate and Glucosamine hydrochloride in a single dose chewable t...
    Medical condition: Knee osteoarthritis with moderate to severe pain.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-000149-12 Sponsor Protocol Number: CXA30007 Start Date*: 2005-04-24
    Sponsor Name:GlaxoSmithKline Research & Development Limited
    Full Title: A Phase III, 12-week, Multicentre, Double-blind, Double-dummy, Randomised, Placebo- and Active Comparator-Controlled, Parallel Group study to investigate the Efficacy and Safety of GW406381 1mg, 5m...
    Medical condition: Osteoarthritis of the Knee
    Disease: Version SOC Term Classification Code Term Level
    7.1 10023476 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) HU (Completed) DK (Completed) DE (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2006-005914-10 Sponsor Protocol Number: CBA109389 Start Date*: 2007-03-22
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: A Multicentre, Randomised, Double-blind, Placebo and Naproxen (500mg) BID controlled, Phase II Proof of Concept, Parallel Group Study to Assess the Efficacy and Safety of Oral GW842166 at Two Dose ...
    Medical condition: Osteoarthritis of the knee
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031165 Osteoarthritis knee LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) ES (Completed) DK (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-003059-20 Sponsor Protocol Number: EMR700692_006 Start Date*: 2013-07-31
    Sponsor Name:Merck KGaA
    Full Title: A multicenter, randomized, double-blind, placebo-controlled, parallel-group trial to investigate the efficacy and safety of different intra-articular (i.a.) dosages of sprifermin in subjects with p...
    Medical condition: Primary osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) EE (Completed) DK (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2010-022625-15 Sponsor Protocol Number: 2010-01 Start Date*: 2010-11-22
    Sponsor Name:Laboratoires ELERTE
    Full Title: Evaluation de l’efficacité de l’association ibuprofène et codéine versus l’ibuprofène seul dans le traitement de la poussée douloureuse de la gonarthrose. Etude en double aveugle, randomisée contrô...
    Medical condition: Gonarthrose fémoro-tibiale uni ou bilatérale en poussée douloureuse
    Disease: Version SOC Term Classification Code Term Level
    12.1 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-002933-23 Sponsor Protocol Number: DAR-INT-14-01 Start Date*: 2016-05-24
    Sponsor Name:TRB CHEMEDICA INTERNATIONAL SA
    Full Title: AN INTERNATIONAL, MULTICENTRE, DOUBLE-BLIND, RANDOMISED STUDY OF THE EFFECT OF DIACEREIN VS CELECOXIB ON SYMPTOMS AND STRUCTURAL CHANGES IN SYMPTOMATIC KNEE OSTEOARTHRITIS PATIENTS AS ASSESSED BY M...
    Medical condition: Pain reduction in symptomatic knee osteoarthritis (OA)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000018839 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) ES (Completed) AT (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2010-020475-23 Sponsor Protocol Number: B0041007 Start Date*: 2010-10-05
    Sponsor Name:Pfizer Inc.235 East 42nd Street, New York, NY 10017
    Full Title: A PHASE 2 RANDOMIZED, DOUBLE-BLINDED, DOUBLE-DUMMY, PLACEBO AND ACTIVE CONTROLLED TWO COHORT TWO-WAY CROSS-OVER, MULTI-CENTRE CLINICAL TRIAL TO EXAMINE THE PAIN RELIEF PRODUCED BY 2 WEEKS OF DAILY...
    Medical condition: Chronic pain in patients with Osteo-arthritis.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-002117-30 Sponsor Protocol Number: 000010/BT Start Date*: 2016-02-16
    Sponsor Name:Bone Therapeutics S.A.
    Full Title: A Two-stage 6-month, Multicentre, Randomised, Double-blind, Controlled Study on the Safety and Efficacy of a Single Intra-articular Administration of JTA-004 in Patients with Symptomatic Knee Osteo...
    Medical condition: Symptomatic osteoarthritis of the knee with Kellgren-Lawrence grade II and III
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    « Previous 1  2  3  4  5  6  7  8  9  Next» Last»»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Wed Jun 04 14:27:52 CEST 2025 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA