Clinical Trials register - Search for Acute myeloid leukaemia

406 result(s) found for: Acute myeloid leukaemia. Displaying page 4 of 21.

EudraCT Number: 2019-003117-33

Sponsor Protocol Number: Pevonedistat-2002

Start Date*: Information not available in EudraCT

Sponsor Name:Millennium Pharmaceuticals, Inc.

Full Title: A Randomized, Open-label, Controlled, Phase 2 Study of Pevonedistat, Venetoclax, and Azacitidine Versus Venetoclax Plus Azacitidine in Adults With Newly Diagnosed Acute Myeloid Leukemia Who Are Unf...

Medical condition: Acute Myeloid Leukemia (AML)

Disease:	Version	SOC Term	Classification Code	Term	Level
	21.0	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10000886	Acute myeloid leukemia	LLT
	20.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10024330	Leukemia acute	LLT
	21.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10024348	Leukemia myelogenous	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: PL (Trial now transitioned) IT (Trial now transitioned) FR (Completed)

Trial results: (No results available)

EudraCT Number: 2008-002288-14

Sponsor Protocol Number: HM1006

Start Date*: 2009-02-10

Sponsor Name:University of Birmingham

Full Title: Phase I Dose Escalation Study of Clofarabine and Liposomal Daunorubicin in Childhood and Adolescent AML

Medical condition: Paediatric patients (6 months to 18 years) diagnosed with AML who are refractory to front line therapy, early first relapse (less than 1 year from diagnosis) and second and subsequent relapse patie...

Disease:	Version	SOC Term	Classification Code	Term	Level
	9.1		10000880	Acute myeloid leukaemia	LLT
	9.1		10066764	Acute myeloid leukaemia progression	LLT

Population Age: Infants and toddlers, Children, Adolescents, Under 18

Gender: Male, Female

Trial protocol: GB (Completed)

Trial results: View results

EudraCT Number: 2005-002847-14

Sponsor Protocol Number: CU 106

Start Date*: 2005-12-16

Sponsor Name:Cardiff University

Full Title: AML16; A National Cancer Research Institute Trial in Acute Myeloid Leukaemia and High Risk Myelodysplastic Syndromes

Medical condition: Acute Myeloid Leukaemia and High Risk Myelodysplastic Syndrome

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	7.1		10000880		LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (Completed) DK (Completed)

Trial results: (No results available)

EudraCT Number: 2009-014455-68

Sponsor Protocol Number: HOVON103AMLTosedostat

Start Date*: 2010-08-16

Sponsor Name:HOVON Foundation

Full Title: A randomized phase II multicenter study with a safety run-in to assess the tolerability and efficacy of the addition of oral tosedostat to standard induction therapy in AML and RAEB ≥ 66 years and ...

Medical condition: patients ≥ 66 years.with a confirmed diagnosis of o AML (not APL) (see appendix A) or o refractory anemia with excess of blasts (RAEB) with an IPSS score ≥ 1.5 OR Patients of any age ≥ 1...

Disease:	Version	SOC Term	Classification Code	Term	Level
	15.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10000886	Acute myeloid leukemia	LLT
	15.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10037803	RAEB	LLT
	15.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10000880	Acute myeloid leukaemia	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: NL (Ongoing) BE (Completed) NO (Completed)

Trial results: (No results available)

EudraCT Number: 2009-013094-17

Sponsor Protocol Number: HOVON103AMLLEN

Start Date*: 2010-04-13

Sponsor Name:HOVON Foundation

Full Title: A randomized phase II multicenter study with a safety run-in to assess the tolerability and efficacy of the addition of oral lenalidomide to standard induction therapy in AML and RAEB ≥ 66 years an...

Disease:	Version	SOC Term	Classification Code	Term	Level
	15.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10000886	Acute myeloid leukemia	LLT
	15.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10037803	RAEB	LLT
	15.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10000880	Acute myeloid leukaemia	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: NL (Ongoing) BE (Completed) NO (Completed)

Trial results: (No results available)

EudraCT Number: 2021-002361-17

Sponsor Protocol Number: AML2521

Start Date*: 2021-11-17

Sponsor Name:FONDAZIONE GIMEMA (GRUPPO ITALIANO MALATTIE EMATOLOGICHE DELL' ADULTO) FRANCO MANDELLI ONLUS

Full Title: A multicentric phase 2 study of venetoclax and azacitidine for the management of the molecular relapse/progression in adult NPM1- mutaded acute myeloid leukemia.

Medical condition: Acute Myeloid Leukemia with NPM1 mutation.

Disease:	Version	SOC Term	Classification Code	Term	Level
	21.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10000880	Acute myeloid leukaemia	PT
	21.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10000880	Acute myeloid leukaemia	PT
	21.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10081513	Acute myeloid leukaemia refractory	PT
	21.0	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10060558	Acute myeloid leukemia recurrent	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: IT (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2009-010114-30

Sponsor Protocol Number: D1531C00009

Start Date*: 2009-06-23

Sponsor Name:AstraZeneca AB

Full Title: A randomised, open-label, multi-centre, 2-stage, parallel group study to assess the efficacy, safety and tolerability of AZD1152 alone and in combination with low dose cytosine arabinoside (LDAC) i...

Medical condition: Acute Myeloid Leukemia

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10000880	Acute myeloid leukaemia	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Prematurely Ended) IT (Prematurely Ended) ES (Prematurely Ended) FR (Completed) GB (Prematurely Ended)

Trial results: View results

EudraCT Number: 2013-000872-14

Sponsor Protocol Number: UCL/11/0519

Start Date*: 2013-07-23

Sponsor Name:University College London

Full Title: Adoptive Immunotherapy with CD25/71 allodepleted donor T cells to improve immunity after unrelated donor stem cell transplant (ICAT)

Medical condition: acute myeloid or acute lymphoblastic leukaemia

Disease:	Version	SOC Term	Classification Code	Term	Level
	16.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10000880	Acute myeloid leukaemia	PT
	16.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10000844	Acute lymphoblastic leukaemia	LLT

Population Age: Adolescents, Under 18, Adults

Gender: Male, Female

Trial protocol: GB (Completed)

Trial results: View results

EudraCT Number: 2018-003025-28

Sponsor Protocol Number: TUD-RELAX1-070

Start Date*: Information not available in EudraCT

Sponsor Name:Technische Universität Dresden

Full Title: Phase-I/II trial for relapsed or refractory AML patients combining cytarabine and mitoxantrone with venetoclax

Medical condition: Patients 18-75 years with acute myeloid leukaemia (AML) at first or second relapse after intensive chemotherapy including allogeneic stem cell transplantation or primary refractory to standard indu...

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	21.0	100000004864	10000886	Acute myeloid leukemia	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Ongoing)

Trial results: (No results available)

EudraCT Number: 2007-005684-10

Sponsor Protocol Number: 1247.3

Start Date*: 2008-08-28

Sponsor Name:Boehringer Ingelheim España S.A.

Full Title: Ensayo clínico abierto de fase I/IIa para evaluar la dosis máxima tolerada, eficacia, seguridad y farmacocinética de BI 811283 en combinación con citarabina en pacientes con leucemia mieloide aguda...

Medical condition: Pacientes con leucemia mieloide aguda no tratados previamente y que no sean elegibles para tratamiento intensivo Previously untreated acute myeloid leukaemia in adult patients that are not eligibl...

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10000886	Acute myeloid leukemia	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: ES (Completed) AT (Prematurely Ended)

Trial results: View results

EudraCT Number: 2005-001721-29	Sponsor Protocol Number: SPD758-216	Start Date*: 2005-12-05
Sponsor Name:SGX Pharmaceuticals, Inc.
Full Title: An Open-Label, Single-Arm, Multi-Center, Phase II/III study of Troxatyl (Troxacitabine) Administered by Continuous Infusion in Patients with Acute Myeloid Leukemia (AML) in second salvage
Medical condition: Acute Myeloid Leukemia (AML)
Disease:
Population Age: Adults, Elderly		Gender: Male, Female
Trial protocol: DE (Prematurely Ended) IT (Completed)
Trial results: (No results available)

EudraCT Number: 2013-000018-39

Sponsor Protocol Number: AMLBFM2012

Start Date*: 2014-11-20

Sponsor Name:Gesellschaft für Pädiatrische Onkologie und Hämatologie (GPOH gGmbH)

Full Title: Clinical trial for the treatment of acute myeloid leukemia in children and adolescents

Medical condition: AML

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	18.0	100000004864	10000886	Acute myeloid leukemia	LLT

Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Children, Adolescents, Under 18

Gender: Male, Female

Trial protocol: DE (Prematurely Ended) AT (Prematurely Ended)

Trial results: (No results available)

EudraCT Number: 2012-005241-20

Sponsor Protocol Number: F14512IN102G1

Start Date*: 2013-02-18

Sponsor Name:Pierre Fabre Medicament

Full Title: Phase I-II study of F14512 in combination with cytarabine in patients 60 years old and older with acute myeloid leukemia.

Medical condition: The scope of this study is the treatment of patient acute myeloid leukaemia.

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	14.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10000880	Acute myeloid leukaemia	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: FR (Prematurely Ended) IT (Prematurely Ended) ES (Completed)

Trial results: View results

EudraCT Number: 2013-003191-12

Sponsor Protocol Number: TUD-2DAUNO-058

Start Date*: 2014-01-31

Sponsor Name:Technische Universität Dresden

Full Title: Randomized comparison between two dose levels of daunorubicin and between one versus two cycles of in-duction therapy for adult patients with acute myeloid leukemia ≤65 years

Medical condition: Newly diagnosed AML other than acute promyelocytic leukemia (APL) according to WHO criteria, i.e. bone marrow aspirate or biopsy must contain ≥20% blasts of all nucleated cells or differential bloo...

Disease:	Version	SOC Term	Classification Code	Term	Level
	21.0	100000004864	10000886	Acute myeloid leukemia	LLT
	21.1	100000004864	10066353	Treatment related acute myeloid leukemia	LLT
	21.0	100000004864	10000887	Acute myeloid leukemia in remission	LLT
	21.0	100000004864	10054294	Acute myeloid leukemia (in remission)	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Completed) CZ (Completed)

Trial results: View results

EudraCT Number: 2010-023499-25

Sponsor Protocol Number: 1230.25

Start Date*: 2011-06-16

Sponsor Name: [...]

Full Title: A phase II/III randomized, open-label study to compare the efficacy and safety of intravenous volasertib in combination with subcutaneous cytarabine versus investigator’s choice of anti-leukemic t...

Medical condition: Relapsed or refractory acute myeloid leukemia in adult patients who are considered not to benefit from / not to be eligible for intensive salvage therapy and/or stem cell transplantation and have n...

Disease:	Version	SOC Term	Classification Code	Term	Level
	13.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10066638	Acute myeloid leukemia progression	LLT
	13.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10000886	Acute myeloid leukemia	LLT
	13.1	10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)	10060558	Acute myeloid leukemia recurrent	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: SE (Prematurely Ended) BE (Prematurely Ended) DE (Prematurely Ended) CZ (Prematurely Ended) AT (Prematurely Ended) NL (Completed) FI (Prematurely Ended)

Trial results: View results

EudraCT Number: 2007-004427-38

Sponsor Protocol Number: 0001A3-300-GL

Start Date*: 2009-01-28

Sponsor Name:Antisoma Research Ltd.

Full Title: Phase 3 Open-Label Randomized Study of Amonafide L-Malate in Combination with Cytarabine Compared to Daunorubicin in Combination with Cytarabine in Patients with Secondary Acute Myeloid Leukemia (AML)

Medical condition: secondary acute myeloid leukemia

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10000886	Acute myeloid leukemia	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Prematurely Ended) FR (Ongoing) AT (Prematurely Ended) HU (Prematurely Ended) EE (Prematurely Ended) CZ (Completed) GB (Prematurely Ended) ES (Prematurely Ended) BE (Completed) IT (Prematurely Ended) GR (Prematurely Ended)

Trial results: (No results available)

EudraCT Number: 2016-004440-12

Sponsor Protocol Number: CPKC412A2408

Start Date*: 2017-11-12

Sponsor Name:Novartis Pharma AG

Full Title: An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of midostaurin (PKC412) in patients 18 years of age or older with newly-diagnosed FLT3-mutated Acute Myeloid Leukemia ...

Medical condition: newly diagnosed FLT3 mutated acute myeloid leukemia

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	21.0	100000004864	10000886	Acute myeloid leukemia	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: SE (Completed) FI (Completed) CZ (Completed) ES (Ongoing) HU (Completed) FR (Completed) BG (Completed) GR (Completed) SK (Completed) LT (Completed) IT (Completed) EE (Completed) HR (Completed) RO (Completed)

Trial results: View results

EudraCT Number: 2012-002026-78

Sponsor Protocol Number: GRASPA-AML-2012-01

Start Date*: 2014-02-26

Sponsor Name:ERYTECH Pharma

Full Title: A Multicentre, open, randomized, controlled phase IIb trial evaluating efficacy and tolerability of GRASPA (L-asparaginase encapsulated in red blood cells) plus low-dose cytarabine vs low-dose cyta...

Medical condition: Acute Myeloid Leukaemia

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	14.1	100000004864	10000886	Acute myeloid leukemia	LLT

Population Age: Elderly

Gender: Male, Female

Trial protocol: IT (Completed) FI (Completed) DE (Completed) ES (Completed)

Trial results: View results

EudraCT Number: 2010-021961-61

Sponsor Protocol Number: VOS-AML-301

Start Date*: 2011-05-19

Sponsor Name:Sunesis Pharmaceuticals, Inc.

Full Title: A Phase 3, Randomized, Controlled, Double Blind, Multinational Clinical Study of the Efficacy and Safety of Vosaroxin and Cytarabine Versus Placebo and Cytarabine in Patients With First Relapsed or...

Medical condition: Relapsed or refractory acute myeloid leukemia

Disease:	Version	SOC Term	Classification Code	Term	Level
	20.0	100000004864	10060558	Acute myeloid leukemia recurrent	LLT
	20.0	100000004864	10054296	Acute myeloid leukemia NOS	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Completed) AT (Completed) GB (Completed) BE (Completed) HU (Completed) ES (Completed) IT (Completed) CZ (Completed)

Trial results: (No results available)

EudraCT Number: 2015-002983-18

Sponsor Protocol Number: ICT-8

Start Date*: 2017-05-08

Sponsor Name:Hybrigenics S.A.

Full Title: Efficacy Study of Inecalcitol in Combination with Decitabine in Acute Myeloid Leukemia Patients Unfit for Standard Chemotherapy

Medical condition: Acute Myeloid Leukemia

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	100000012984	10000886	Acute myeloid leukemia	LLT

Population Age: Elderly

Gender: Male, Female

Trial protocol: BE (Prematurely Ended) ES (Prematurely Ended)

Trial results: (No results available)

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Clinical trials for Acute myeloid leukaemia