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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,380 result(s) found. Displaying page 451 of 2,219.
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    EudraCT Number: 2009-015993-37 Sponsor Protocol Number: SAN-FORST-001 Start Date*: 2009-11-06
    Sponsor Name:Institut für Klinische Forschung und Entwicklung (ikfe) GmbH
    Full Title: Beta Cell Relieving and Cardiovascular Protective Effects of LANTUS Treatment in Type 2 Diabetes Patients – Investigation on Postprandial Excursions of Proinsulin and PAI-1 Levels
    Medical condition: Type 2 Diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    12.0 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-003851-20 Sponsor Protocol Number: C-10-151 Start Date*: 2012-01-11
    Sponsor Name:Alcon Research, Ltd.
    Full Title: A Multicente, Observer-Masked Study of the Safety and Efficacy of MDPF Travoprost, 0.004% Compared to TRAVATAN in Patients with Open-Angle Glaucoma or Ocular Hypertension
    Medical condition: Open-Angle Glaucoma or Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-003866-34 Sponsor Protocol Number: 2553 Start Date*: 2012-09-24
    Sponsor Name:North Bristol NHS Trust (NBT)
    Full Title: A Placebo-Controlled, Randomised, Double-Blind Trial to Assess the Safety and Efficacy of Intermittent Bilateral Intraputamenal Glial Cell Line-Derived Neurotrophic Factor (GDNF) Infusions Administ...
    Medical condition: Parkinson's disease
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004852 10034008 Parkinson's syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-022240-21 Sponsor Protocol Number: ISIS183750-CS4 Start Date*: 2011-04-29
    Sponsor Name:Isis Pharmaceuticals Inc.
    Full Title: A Phase 1b/2 Study of Carboplatin-Paclitaxel, with or without ISIS 183750 (an eIF4E Inhibitor), in Patients with Stage IV Non-Small Cell Lung Cancer
    Medical condition: Stage IV Non-Small Cell Lung Cancer (NSCLC; including patients with pleural effusion who were previously classified as Stage IIIB)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029522 Non-small cell lung cancer stage IV PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-007974-45 Sponsor Protocol Number: EKZ-AMC001 Start Date*: 2009-07-16
    Sponsor Name:AMC
    Full Title: Phase II trial of the combination of gemcitabine and 131I-MIBG therapy in paediatric patients with relapsed or progressive neuroblastoma
    Medical condition: relapsed or progressive neuroblastoma in pediatric patients of 1 to 18 years
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing) DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-019837-85 Sponsor Protocol Number: CUTACETUX Start Date*: 2010-05-12
    Sponsor Name:CHU de Poitiers
    Full Title: Étude de la toxicité cutanée du cétuximab (anti-Epidermal Growth Factor Receptor): recherche d’un lien entre la réponse inflammatoire cutanée et la réponse radiologique.
    Medical condition: METASTATIC COLORECTAL CANCER
    Disease: Version SOC Term Classification Code Term Level
    12.1 10052362 Metastatic colorectal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-002986-39 Sponsor Protocol Number: DXM/AMT Start Date*: 2011-09-12
    Sponsor Name:Profil Institut für Stoffwechselforschung GmbH
    Full Title: A Phase IIa, Double-Blind, Placebo-Controlled, Randomised, Fourfold Cross-Over Study to Investigate the Glucose Lowering Effects of Dextromethorphan and Amantadine in Subjects with Type 2 Diabetes ...
    Medical condition: Type 2 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    14.0 10027433 - Metabolism and nutrition disorders 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-001121-24 Sponsor Protocol Number: P00804 Start Date*: 2011-04-21
    Sponsor Name:Papworth Hospital NHS Trust
    Full Title: Prospective randomised controlled trial of video assisted thorascopic (VATS) cytoreductive pleurectomy compared to talc pleurodesis in patients with suspected or proven malignant mesothelioma
    Medical condition: Mesothelioma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-005529-74 Sponsor Protocol Number: ML19982 Start Date*: 2006-03-16
    Sponsor Name:Roche (Hungary) Ltd.
    Full Title: A randomised, open-label, multi-national, multi-center study to investigate the impact of bone-marker feedback (at 3 months) on adherence to once monthly ibandronate treatment of patients with post...
    Medical condition: osteoporosis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10031282 PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: SI (Completed) SK (Completed) LV (Completed)
    Trial results: View results
    EudraCT Number: 2011-000388-28 Sponsor Protocol Number: 00658;MK-0683-201 Start Date*: 2011-06-30
    Sponsor Name:University Medical Center Freiburg
    Full Title: Safety of Vorinostat in combination with Bortezomib, Doxorubicin and Dexamethasone (VBDD) in patients with refractory or relapsed multiple myeloma
    Medical condition: Relapsed or refractory multiple myeloma
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004864 10028228 Multiple myeloma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-004050-29 Sponsor Protocol Number: PHI116581 Start Date*: 2013-01-07
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: A four-week Phase IIa, randomized, double-blind, placebocontrolled, parallel-group, multi-center study to evaluate the safety, efficacy and pharmacokinetics of GSK1278863 in subjects with anemia as...
    Medical condition: Anemia associated with chronic kidney disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004857 10064848 Chronic kidney disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-019767-11 Sponsor Protocol Number: Ö-PKU1 Start Date*: 2010-09-08
    Sponsor Name:Graz Medical University
    Full Title: Ö-PKU 1 – Evaluation of a Test for the identication of BH4 responsive PKU patients
    Medical condition: Hyperphenylalaninaemia (HPA) in adult and paediatric patients of 4 years of age and over with phenylketonuria (PKU).
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-019777-15 Sponsor Protocol Number: GLP114130 Start Date*: 2010-09-10
    Sponsor Name:GlaxoSmithKline LLC
    Full Title: A Randomized, Double-Blind, Active-Controlled, Parallel-Group, Multicenter Study to Determine the Efficacy and Safety of Albiglutide as Compared With Sitagliptin in Subjects With Type 2 Diabetes Me...
    Medical condition: Type 2 Diabetes Mellitus With Renal Impairment
    Disease: Version SOC Term Classification Code Term Level
    14.0 10027433 - Metabolism and nutrition disorders 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-019778-34 Sponsor Protocol Number: D1050292 Start Date*: 2011-03-14
    Sponsor Name:Sunovion, Inc.
    Full Title: A RANDOMIZED, 6-WEEK, DOUBLE-BLIND, PLACEBO-CONTROLLED, FLEXIBLE-DOSE, PARALLEL-GROUP STUDY OF LURASIDONE ADJUNCTIVE TO LITHIUM OR DIVALPROEX FOR THE TREATMENT OF BIPOLAR I DEPRESSION IN SUBJECTS ...
    Medical condition: Bipolar disorder
    Disease: Version SOC Term Classification Code Term Level
    12.1 10004936 Bipolar depression LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Completed) LT (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2011-005111-91 Sponsor Protocol Number: RBHP2011LUSSON Start Date*: 2012-01-19
    Sponsor Name:CHU de Clermont-Ferrand
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    14.1 10047065 - Vascular disorders 10034633 Peripheral vascular disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-023776-52 Sponsor Protocol Number: Lisette-1 Start Date*: 2011-01-19
    Sponsor Name:
    Full Title: Optimizing tamoxifen therapy through the induction of CYP3A4, CYP2C and CYP2D6 mediated metabolism
    Medical condition: Breast cancer
    Disease: Version SOC Term Classification Code Term Level
    12.1 10006187 Breast cancer LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-023789-33 Sponsor Protocol Number: 300904BS Start Date*: 2011-02-17
    Sponsor Name:Valderm ApS
    Full Title: A phase IIa, multicenter, randomized, two-arm, observer-blind, vehicle and reference controlled proof of concept trial to investigate intra-individually (left/ right) the antipsoriatic efficacy and...
    Medical condition: Male or female subjects with stable plaque psoriasis
    Disease: Version SOC Term Classification Code Term Level
    13.1 10040785 - Skin and subcutaneous tissue disorders 10050576 Psoriasis vulgaris LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-003206-25 Sponsor Protocol Number: NRL001-01/2011(SEFI) Start Date*: 2012-01-25
    Sponsor Name:Norgine Ltd
    Full Title: A multi-centre, phase II, double-blind, randomised, placebo-controlled, parallel group, dose-ranging study in patients with faecal incontinence; to evaluate the efficacy, safety and tolerability of...
    Medical condition: Faecal incontinence
    Disease: Version SOC Term Classification Code Term Level
    14.1 10017947 - Gastrointestinal disorders 10016092 Faecal incontinence PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) CZ (Completed) DE (Completed) ES (Completed) GB (Completed) IT (Completed) HU (Completed)
    Trial results: Removed from public view
    EudraCT Number: 2011-003208-19 Sponsor Protocol Number: GWID10160 Start Date*: 2011-11-16
    Sponsor Name:GW Pharma Ltd.
    Full Title: A randomised, double-blind, placebo-controlled parallel group, pilot study of GWP42003 in the symptomatic treatment of ulcerative colitis.
    Medical condition: Symptoms of diarrhoea, rectal bleeding, stool frequency and inflammation in subjects with ulcerative colitis
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004856 10045365 Ulcerative colitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2010-024657-36 Sponsor Protocol Number: DSR-01 Start Date*: 2011-05-17
    Sponsor Name:Statens Serum Institut
    Full Title: Metronidazol for the treatment of dientamoebiasis in children in Denmark – A randomized, placebo-controlled, double-blinded clinical trial.
    Medical condition: Presumed symptomatic gastrointestinal infection with the protozoan Dientamoeba fragilis.
    Disease: Version SOC Term Classification Code Term Level
    13.1 10017947 - Gastrointestinal disorders 10006051 Bowel dysfunction LLT
    13.1 10017947 - Gastrointestinal disorders 10016766 Flatulence PT
    13.1 10021881 - Infections and infestations 10021907 Infectious diarrhea LLT
    13.1 10017947 - Gastrointestinal disorders 10034453 Perianal itching LLT
    13.1 10017947 - Gastrointestinal disorders 10017999 Gastrointestinal pain PT
    13.1 10027433 - Metabolism and nutrition disorders 10016165 Failure to thrive PT
    13.1 10021881 - Infections and infestations 10067720 Parasitic gastroenteritis PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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