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Clinical trials for Ear

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    371 result(s) found for: Ear. Displaying page 5 of 19.
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    EudraCT Number: 2020-006011-23 Sponsor Protocol Number: 130669 Start Date*: 2021-03-02
    Sponsor Name:Petra Pietarinen
    Full Title: Laryngeaalisen leukoplakian mikrobilääkehoito -tutkimusprojekti
    Medical condition: Krooninen laryngiitti
    Disease:
    Population Age: Adults, Elderly Gender:
    Trial protocol: FI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2017-000658-20 Sponsor Protocol Number: 7621 Start Date*: 2017-04-24
    Sponsor Name:
    Full Title: Combinated systemic and intratympanic steroid therapy in idiopathic sudden sensorineural hearing loss
    Medical condition: Idiopathic Sudden Sensorineural Hearing Loss
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-005484-32 Sponsor Protocol Number: VN-FT-01 Start Date*: 2015-05-28
    Sponsor Name:Lund University
    Full Title: Double-blind, randomized placebo controlled study on the effect from cortisone treatment of vestibular neuritis - function, subjective well-being and stress
    Medical condition: Acute vestibular syndrome better known as Vestibular neuritis
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004863 10047392 Vestibular nerve damage LLT
    17.1 100000004854 10047388 Vestibular function disorder LLT
    17.1 100000004862 10051781 Vestibular paralysis LLT
    17.1 100000004854 10013285 Disorder vestibular LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-013702-14 Sponsor Protocol Number: BETNV009 Start Date*: 2010-08-13
    Sponsor Name:Hospital of the University of Munich
    Full Title: Effects of betahistine on central vestibular compensation in acute unilateral vestibular failure: a double-blind, placebo-controlled trial
    Medical condition: vestibular failure (vestibular neuritis)
    Disease: Version SOC Term Classification Code Term Level
    18.0 10013993 - Ear and labyrinth disorders 10047386 Vestibular disorder PT
    18.0 10029205 - Nervous system disorders 10029240 Neuritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2016-003927-45 Sponsor Protocol Number: SENS-111-201 Start Date*: 2017-05-04
    Sponsor Name:Sensorion SA
    Full Title: A multicentre, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of 2 dose regimens of orally administered SENS-111 (100mg and 200mg) given during 4 days in patie...
    Medical condition: Acute Unilateral Vestibulopathy
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021881 - Infections and infestations 10047393 Vestibular neuronitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) CZ (Completed) HU (Completed) ES (Prematurely Ended) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2020-000585-41 Sponsor Protocol Number: OG-061-01 Start Date*: 2020-11-06
    Sponsor Name:T-Balance Therapeutics GmbH
    Full Title: Effects of tregalizumab on allergen-induced airway responses and airway inflammation in asthmatic patients
    Medical condition: mild controlled allergic asthma and house-dust mite (HDM) allergy
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004855 10001705 Allergic asthma LLT
    20.0 100000004870 10020419 House dust mite allergy LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-000066-37 Sponsor Protocol Number: NM-V-101 Start Date*: 2013-01-16
    Sponsor Name:Nordmark Arzneimittel GmbH & Co. KG
    Full Title: Double-blind, randomized, placebo-controlled study on efficacy, safety and tolerability of ancrod in patients with sudden sensorineural hearing loss
    Medical condition: sudden sensorineural hearing loss (SSHL)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004854 10040016 Sensorineural hearing loss LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-005246-42 Sponsor Protocol Number: 0796-19 Start Date*: 2021-12-28
    Sponsor Name:INTAS PHARMACEUTICALS LIMITED
    Full Title: A Multicenter, Three- arm, Double- blind, Double dummy, Parallel-group, placebo controlled Study for efficacy and safety evaluation of prolonged release formulation of Betahistine PR 48 mg once dai...
    Medical condition: Menière´s disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 10013993 - Ear and labyrinth disorders 10047340 Vertigo PT
    20.0 10013993 - Ear and labyrinth disorders 10022398 Inner ear signs and symptoms HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing) FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-002580-13 Sponsor Protocol Number: LPA111834 Start Date*: 2009-05-05
    Sponsor Name:GlaxoSmithKline Research & Development Limited
    Full Title: A randomised, double-blind, placebo-controlled, 2-period cross-over study to evaluate the effect of treatment with GSK2190915 on the allergen-induced asthmatic response in subjects with mild asthma
    Medical condition: Mild asthma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001705 Allergic asthma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2019-003463-22 Sponsor Protocol Number: CLOTOT3-16IA03 Start Date*: 2020-04-29
    Sponsor Name:Laboratorios Salvat, S.A.
    Full Title: A Phase III, Multicenter, Randomized, Double-Blind Clinical Trial to Assess the Efficacy and Safety of Clotrimazole 1% Otic Solution Compared to Placebo for the Treatment of Fungal Otitis Externa (...
    Medical condition: Fungal Otitis Externa (Otomycosis)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10052557 Otitis externa fungal PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing) PT (Completed) BG (Completed) RO (Completed)
    Trial results: View results
    EudraCT Number: 2015-001496-48 Sponsor Protocol Number: OTI179 Start Date*: Information not available in EudraCT
    Sponsor Name:BIOCODEX
    Full Title: Evaluation de l'efficacité d’une solution de chlorhydrate de lidocaïne 1% et de phénazone 4% en gouttes auriculaires (Otipax®) dans l’otite moyenne aiguë congestive de l’enfant Etude clinique ouv...
    Medical condition: Congestive acute otitis media of children
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-003012-23 Sponsor Protocol Number: AQX-1125-200 Start Date*: 2011-10-10
    Sponsor Name:AQUINOX PHARMACEUTICALS INC
    Full Title: A phase IIa single-centre, randomised, double-blind, placebo-controlled, two-way cross-over allergen challenge study to evaluate the effect of treatment with once daily AQX-1125 on the late asthmat...
    Medical condition: Mild to moderate asthma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-000388-15 Sponsor Protocol Number: VesPa Start Date*: 2016-08-31
    Sponsor Name:University of the University of Munich
    Full Title: Prophylactic treatment of vestibular paroxysmia with carbamazepine: a prospective, randomized, placebo-controlled, cross-over, multi-center trial
    Medical condition: The main symptoms of vestibular paroxysmia are brief attacks of rotatory or postural vertigo lasting seconds to a few minutes with or without ear symptoms (tinnitus and hypoacusis). As in trigemina...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-000857-29 Sponsor Protocol Number: ENDOHOT Start Date*: 2019-09-04
    Sponsor Name:Rigshospitalet - University Hospital of Copenhagen
    Full Title: Hyperbaric oxygen treatment in humans with Gram Positive Cocci endocarditis
    Medical condition: Bacterial Endocarditis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10057480 Hyperbaric oxygen therapy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2018-001958-10 Sponsor Protocol Number: MD2018 Start Date*: 2018-10-25
    Sponsor Name:Abteilung für Hals-, Nasen- und Ohrenkrankheiten MUW, AKH Wien
    Full Title: Dexamethasone 21-dihydrogenphosphat and Triamcinolone acetonide in the treatment of Menière´s disease: a randomized, multicentric efficacy trial
    Medical condition: In our study we try to evaluate the effect of intratympanic Triamcinolon acetonide and Dexamethason 21-dihydrohenphosphat on vertigo control calculation, Hydrops MRI, vHIT (video head impuls test),...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: View results
    EudraCT Number: 2015-001788-37 Sponsor Protocol Number: HCA-2015-2 Start Date*: 2015-06-29
    Sponsor Name:Heart Center Co. Tampere University Hospital
    Full Title: Effects of volume changes to the plethysmography signal on major surgery patients
    Medical condition: Patients scheduled for elective CABG (Coronary artery bypass surgery). Patients scheduled for elective open major abdominal surgery (gastrointestinal surgery).
    Disease: Version SOC Term Classification Code Term Level
    18.0 10042613 - Surgical and medical procedures 10011090 Coronary artery surgery LLT
    18.0 10042613 - Surgical and medical procedures 10068093 Gastrointestinal surgery PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-002370-21 Sponsor Protocol Number: 06/Q2002/25 Start Date*: 2006-09-20
    Sponsor Name:North Bristol NHS Trust
    Full Title: Comparison of oral and intravenous paracetamol plasma levels when given as premedication for perioperative analgesia
    Medical condition: Peri-operative analgesia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-005842-39 Sponsor Protocol Number: 226361 Start Date*: 2013-12-20
    Sponsor Name:NU-sjukvården, Norra Älvsborgs Länssjukhus
    Full Title: Treatment of eosinophilic esophagitis with mometason furoat aerosol: a randomised, placebo-controled phase II study for evaluation of treatment effect on group level including symtom questionnaires
    Medical condition: Eosinphilic Esophagitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-004620-10 Sponsor Protocol Number: 719-13 Start Date*: 2014-12-22
    Sponsor Name:Johan Hellgren
    Full Title: A double blind, placebo controlled randomized study of nasal steroid spray treatment on the quality of life and objective sleep parameters in children with sleep disorder breathing.
    Medical condition: Sleep disordered breathing due to enlarged tonsils and/or adenoid
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2016-004544-10 Sponsor Protocol Number: AUT-001 Start Date*: 2017-09-18
    Sponsor Name:Audion Therapeutics BV
    Full Title: A phase I/II multiple ascending dose open-label safety and efficacy study of the Notch Inhibitor LY3056480 in patients with mild to moderate sensorineural hearing loss.
    Medical condition: Sensorineural hearing loss (SNHL)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004854 10040016 Sensorineural hearing loss LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) GR (Completed) DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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