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Clinical trials for Ocular hypertension

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44344   clinical trials with a EudraCT protocol, of which   7373   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    166 result(s) found for: Ocular hypertension. Displaying page 5 of 9.
    « Previous 1  2  3  4  5  6  7  8  9  Next»
    EudraCT Number: 2019-000921-39 Sponsor Protocol Number: PH-BRINLOL-01 Start Date*: 2019-04-24
    Sponsor Name:PHARMATHEN SA
    Full Title: A prospective, phase III, multicenter, randomized, investigator-masked, parallel groups, non-inferiority clinical trial for the comparison of efficacy and safety and of a generic fixed combination ...
    Medical condition: open-angle glaucoma or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed) CY (Completed)
    Trial results: View results
    EudraCT Number: 2013-001250-10 Sponsor Protocol Number: LT2345-PIV-02/13 Start Date*: 2013-11-06
    Sponsor Name:Laboratoires Thea
    Full Title: Safety and Efficacy assessment of Monoprost® (unpreserved latanoprost) in comparison with Lumigan® 0.01 % and Lumigan® 0.03% UD, in patients with open angle glaucoma or ocular hypertension, stabili...
    Medical condition: glaucoma, ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    17.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) ES (Completed) GR (Completed) FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-000168-10 Sponsor Protocol Number: BVT.28949-002 Start Date*: 2006-08-09
    Sponsor Name:Biovitrum AB
    Full Title: A 4-week, double-masked, parallel-group, randomized , multicenter, proof of concept study comparing the efficacy and safety of two dose levels of BVT.28949 with placebo in patients with ocular hype...
    Medical condition: Ocular hypertension or open angle glaucoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-005379-10 Sponsor Protocol Number: HUS_MON_2014-01 Start Date*: 2015-05-18
    Sponsor Name:Emiliano Hernández Galilea
    Full Title: Study of tear osmolarity and Quality of Life on patients treated with unpreserved latanoprost 0.005%
    Medical condition: Chronic open angle glaucoma and ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    17.1 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-024513-31 Sponsor Protocol Number: C-10-041 Start Date*: 2011-06-15
    Sponsor Name:Alcon Research, Ltd.
    Full Title: Efficacy and Safety of Brinzolamide 10 mg/ml / Brimonidine 2 mg/ml Eye Drops, Suspension Compared to Brinzolamide 10 mg/ml Eye Drops, Suspension plus Brimonidine 2 mg/ml Eye Drops, Solution in Pati...
    Medical condition: Patients with open-angle glaucoma or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) SE (Completed) PT (Completed) HU (Completed) LT (Completed) DE (Completed) BE (Prematurely Ended) NL (Completed) AT (Completed) ES (Completed) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-022178-14 Sponsor Protocol Number: 659 Start Date*: 2011-02-14
    Sponsor Name:Dr. Gerhard Mann Chem.-Pharm. Fabrik GmbH/Bausch & Lomb
    Full Title: A Randomized, Multicenter, Single-Masked, Parallel-Group Dose Finding Study Comparing the Safety and Efficacy of BOL-303259-X (0.006%, 0.012%, 0.024% and 0.040%) to Latanoprost 0.005% in Subjects w...
    Medical condition: Open Angle Glaucoma or Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed) CZ (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2013-004302-26 Sponsor Protocol Number: 201350 Start Date*: 2014-09-05
    Sponsor Name:Santen Oy
    Full Title: A phase I study to evaluate the pharmacokinetics, safety and tolerability of preservative free tafluprost ophthalmic solution (0.0015%) in pediatric patients diagnosed with glaucoma or ocular hyper...
    Medical condition: Glaucoma or Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    18.1 10010331 - Congenital, familial and genetic disorders 10011762 Cystic fibrosis PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed) HU (Completed) SK (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2022-002524-12 Sponsor Protocol Number: BNZ-20-01-2022 Start Date*: 2023-04-13
    Sponsor Name:AZAD Pharma AG
    Full Title: A prospective, phase III, multicenter, randomized, investigator-blinded, two-arm, parallel groups, non-inferiority clinical trial for the comparison of efficacy and safety of a preservative-free Br...
    Medical condition: GLAUCOMA , OCCULAR HYPERTENSION
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-021507-24 Sponsor Protocol Number: 192024-050 Start Date*: 2011-02-23
    Sponsor Name:Allergan Limited
    Full Title: A Multicenter, Double-masked, Randomized, Parallel Study of the Safety and Efficacy of Bimatoprost 0.03%/Timolol 0.5% Preservative freeOphthalmic Solution Compared with GANFORT® (bimatoprost 0.03%/...
    Medical condition: Glaucoma or Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.0 10015919 - Eye disorders 10008833 Chronic angle-closure glaucoma LLT
    14.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    14.0 10015919 - Eye disorders 10009034 Chronic open angle glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) HU (Completed) CZ (Completed) GB (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2017-000846-23 Sponsor Protocol Number: LT4032-301 Start Date*: 2018-09-16
    Sponsor Name:Laboratoires THEA
    Full Title: Efficacy and safety assessment of T4032 (unpreserved bimatoprost 0.01%) versus Lumigan® 0.01% in ocular hypertensive or glaucomatous patients.
    Medical condition: glaucoma, ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) GB (GB - no longer in EU/EEA) DE (Completed) LT (Completed) GR (Completed) BE (Completed) PL (Completed) ES (Completed) SK (Completed) CZ (Completed) LV (Completed) BG (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2014-005273-37 Sponsor Protocol Number: 201450 Start Date*: 2015-02-17
    Sponsor Name:Santen Oy
    Full Title: A phase IV study on the changes in ocular signs and symptoms in patients with ocular hypertension or open-angle glaucoma switched from Ganfort® eye drops (bimatoprost 0.03%/timolol 0.5%) to Taptiq...
    Medical condition: Glaucoma or Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    17.1 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    17.1 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    17.1 10015919 - Eye disorders 10074026 Exfoliation glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2019-001642-18 Sponsor Protocol Number: WP3 Start Date*: 2019-12-05
    Sponsor Name:Department of Ophthalmology, Rigshospitalet-Glostrup
    Full Title: Effect on the ocular surface when treating glaucoma with eye drops: an investigation of the conjunctival goblet cells
    Medical condition: Open angular glaucoma and ocular hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2005-002574-29 Sponsor Protocol Number: 77550 Start Date*: 2005-08-02
    Sponsor Name:Santen Oy
    Full Title: Pharmacodynamics of tafluprost 0.0015% eye drops: a comparison between the preserved and unpreserved formulation in patients with open-angle glaucoma or ocular hypertension.
    Medical condition: Open angle glaucoma or ocular hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-002777-27 Sponsor Protocol Number: CF101-231GL Start Date*: 2011-12-30
    Sponsor Name:Can-Fite BioPharma Ltd.
    Full Title: A Phase 2, Randomized, Double-Masked, Placebo-Controlled, Parallel-Group Study of the Safety and Efficacy of Daily CF101 Administered Orally in Subjects with Elevated Intraocular Pressure
    Medical condition: patients with elevate intraocular pressure
    Disease: Version SOC Term Classification Code Term Level
    18.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Completed)
    Trial results: View results
    EudraCT Number: 2010-021613-23 Sponsor Protocol Number: Start Date*: 2010-11-24
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and University of Cambridge
    Full Title: HYPAZ: An open-label investigation into hypertension induced by pazopanib therapy
    Medical condition: Hypertension induced by pazopanib treatment of various cancer types
    Disease: Version SOC Term Classification Code Term Level
    16.1 10038738 - Respiratory, thoracic and mediastinal disorders 10037400 Pulmonary hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-004974-94 Sponsor Protocol Number: 74460 Start Date*: 2005-02-09
    Sponsor Name:Santen Oy
    Full Title: Efficacy and safety of tafluprost 0.0015% eye drops as adjunctive therapy with timolol 0.5% eye drops. A randomised, placebo-controlled, phase III study in patients with open-angle glaucoma or ocul...
    Medical condition: Open angle glaucoma or ocular hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: EE (Completed) LV (Completed)
    Trial results: View results
    EudraCT Number: 2012-000044-10 Sponsor Protocol Number: QTM/OMN0114 Start Date*: 2015-03-30
    Sponsor Name:OMNIVISION
    Full Title: Open, Observer-blind, two Parallel Group, Randomized, Multicentric Clinical Phase III Trial on the Comparison of Efficacy and Tolerability of a New Preservative-free Formulation of the Fixed Combin...
    Medical condition: Open Angle Glaucoma or Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    18.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    18.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-024272-26 Sponsor Protocol Number: GLC-05-10 Start Date*: 2011-04-14
    Sponsor Name:IRCCS- FONDAZIONE G.B. BIETTI PER LO STUDIO E LA RICERCA IN OFTALMOLOGIA-ONLUS
    Full Title: Comparison of the effects of Bimatoprost 0.01% and Timolol 0.5% on circadian intraocular pressure
    Medical condition: glaucoma and ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2008-006718-10 Sponsor Protocol Number: Alcon SMA-08-16 Start Date*: 2009-08-17
    Sponsor Name:Alcon Laboratories, Inc.
    Full Title: The Efficacy and Safety of Travoprost 0.004% versus Tafluprost 0.005% in Primary Open-Angle Glaucoma or Ocular Hypertensive Patients.
    Medical condition: primary open-angle glaucoma ocular hypertension pigment dispersion glaucoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2016-002281-31 Sponsor Protocol Number: Piromelatine-IOP1 Start Date*: 2016-09-19
    Sponsor Name:Neurim Pharmaceuticals (1991) Ltd.
    Full Title: A randomized, double-blind, placebo-controlled, study of oral treatment of piromelatine in patients with ocular hypertension (OHT) or primary open angle glaucoma (POAG).
    Medical condition: ocular hypertension primary open angle glaucoma
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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