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Clinical trials for Shock

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    318 result(s) found for: Shock. Displaying page 6 of 16.
    EudraCT Number: 2018-000404-42 Sponsor Protocol Number: RH-ITA-007 Start Date*: 2018-03-20
    Sponsor Name:Dept. of Intensive Care, Copenhagen University Hospital, Rigshospitalet
    Full Title: The Conservative vs. Liberal Approach to fluid therapy of Septic Shock in Intensive Care Trial
    Medical condition: Septic shock
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10040050 Sepsis NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) SE (Completed) CZ (Completed) ES (Prematurely Ended) BE (Completed) FI (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-002732-25 Sponsor Protocol Number: 0105 Start Date*: 2006-02-01
    Sponsor Name:Geir Øystein Andersen, Department of Cardiology, Ulleval University Hospital
    Full Title: Safety and efficacy of levosimendan in patients with acute myocardial infarction complicated by symptomatic left ventricular failure
    Medical condition: Patients with acute myocardial infarction developing acute heart failure after primary PCI (percutaneus coronary intervention). Some patients in a predefined subgroup are categorized as patients in...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-001475-11 Sponsor Protocol Number: 2007-11 Start Date*: 2007-10-09
    Sponsor Name:Assistance Publique Hopitaux de marseille
    Full Title: Influence de la vitesse de perfusion du sérum salé hypertonique/hydroxyethylamidon sur l’hémodynamique systémique au cours du choc septique et hémorragique.
    Medical condition: SHOCK HYPOVOLEMIQUE OF SEPTIC OR HAEMORRHAGIC ORIGIN
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-001874-89 Sponsor Protocol Number: ZKSJ0112_ARISS Start Date*: 2019-02-25
    Sponsor Name:Friedrich-Schiller-Universität Jena
    Full Title: Randomised controlled multicentre study of albumin replacement therapy in septic shock
    Medical condition: Septic Shock
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004848 10001559 Albumin abnormal LLT
    21.0 100000004848 10035167 Plasma albumin abnormal LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-004886-33 Sponsor Protocol Number: A06-269 Start Date*: 2007-06-05
    Sponsor Name:University of Athens, Medical school
    Full Title: A DOUBLE-BLIND RANDOMIZED PLACEBO-CONTROLLED CLINICAL TRIAL OF THE SAFETY AND IMMUNOMODULATORY THERAPY FOR THE MANAGEMENT OF SEPSIS
    Medical condition: septic syndrome
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-003484-39 Sponsor Protocol Number: AGO/2008/006 Start Date*: 2008-08-20
    Sponsor Name:University Hospital Ghent
    Full Title: Farmacokinetische evaluatie van de eerste intraveneuze dosering van quinolones bij Intensieve Zorgen (IZ) patiënten met septische shock.
    Medical condition: IZ-patiënten met ernstige infecties leidend tot septische shock
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-002672-86 Sponsor Protocol Number: Altshock Start Date*: 2015-04-20
    Sponsor Name:AO OSPEDALE NIGUARDA CA' GRANDA
    Full Title: PHASE II CLINICAL TRIAL FOR A STEPWISE PROGRESSION IN THE TREATMENT OF CARDIOGENIC SHOCK
    Medical condition: Patients affected by cardiogenic shock
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-001078-27 Sponsor Protocol Number: 19999 Start Date*: 2020-06-16
    Sponsor Name:Bayer AG
    Full Title: Safety and efficacy of inhaled pegylated adrenomedullin (PEG-ADM) in patients suffering from Acute Respiratory Distress Syndrome (ARDS): a double-blind, randomized, placebo-controlled, multicenter ...
    Medical condition: Acute respiratory distress syndrome (ARDS)
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10001052 Acute respiratory distress syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) CZ (Completed) AT (Prematurely Ended) IT (Prematurely Ended) GR (Prematurely Ended) NL (Prematurely Ended) BE (Completed) DK (Prematurely Ended) IE (Prematurely Ended) FI (Prematurely Ended) HU (Prematurely Ended) SK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-001244-26 Sponsor Protocol Number: COV-2-SOLNATIDE-20 Start Date*: 2020-04-11
    Sponsor Name:Department of Clinical Pharmacology, Medical University of Vienna, Vienna Austria
    Full Title: COVID-19: Efficacy of solnatide to treat pulmonary permeability oedema in SARS-Cov-2 positive patients with moderate-to-severe ARDS - a pilot-trial.
    Medical condition: Pulmonary permeability oedema in SARS-Cov-2 positive patients with moderate-to-severe ARDS
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10003083 ARDS LLT
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10037423 Pulmonary oedema PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-024273-38 Sponsor Protocol Number: UZ1 Start Date*: 2013-11-27
    Sponsor Name:University Hospitals Leuven
    Full Title: Supplemental corticosteroids in cirrhotic hypotensive patients with suspicion of sepsis
    Medical condition: Cirrhotic patients under vasopressors admitted to the ICU because of persisting hypotension and with suspected infection.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Prematurely Ended) CZ (Completed) GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2009-014420-37 Sponsor Protocol Number: PICCHE Start Date*: 2009-09-15
    Sponsor Name:AZIENDA OSPEDALIERA ISTITUTI CLINICI DI PERFEZIONAMENTO DI MILANO
    Full Title: PEDIATRIC INTENSIVE CARE C PROTEIN HEMOSTASIS STUDY
    Medical condition: SEVERE SEPSIS/ SEPTIC SHOCK
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-004769-41 Sponsor Protocol Number: 7572 Start Date*: 2020-02-18
    Sponsor Name:Hôpitaux Universitaires de Strasbourg
    Full Title: Prospective randomized versus placebo study evaluating the feasibility of plasma therapy in septic shock induced coagulopathy
    Medical condition: Septic shock
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006984-21 Sponsor Protocol Number: MAXSEP Start Date*: 2007-05-29
    Sponsor Name:Friedrich-Schiller-University of Jena
    Full Title: prospective, randomized, open, multicentre trial to assess the influence of empiric antibiotic monotherapy with meropenem (Meronem) versus combination with moxifloxacin (Avalox) on the organ functi...
    Medical condition: severe sepsis / septic shock
    Disease: Version SOC Term Classification Code Term Level
    9.1 10040047 Sepsis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001709-10 Sponsor Protocol Number: P170924J Start Date*: 2018-10-30
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: I-MICRO: Ilomedine in the treatment of septic shock with persistence of microperfusion disorders: Multicenter randomized and controlled double-blind study.
    Medical condition: Ilomedin: Cardiology - Angeiology - Vasodilators and anti-ischemic drugs: Severe ischemia: route of injection (Prostaglandin analogs: iloprost)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10040070 Septic shock PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-003726-93 Sponsor Protocol Number: HALO-HCA2017 Start Date*: 2019-07-31
    Sponsor Name:HELLENIC INSTITUTE FOR THE STUDY OF SEPSIS
    Full Title: Heparin Anticoagulation to improve Outcomes in septic shock : The HALO International phase II RCT.
    Medical condition: HEPARIN Anticoagulation to improve outcomes in septic shock : the HALO International Phase II RCT
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10040047 Sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-004726-42 Sponsor Protocol Number: 17/BW/MAT/PO14 Start Date*: 2017-02-15
    Sponsor Name:Birmingham Women's Hospital
    Full Title: Randomised controlled trial on the use of synthetic osmotic cervical dilator in induction of labour in comparison to dinoprostone vaginal insert
    Medical condition: Induction of Labour
    Disease: Version SOC Term Classification Code Term Level
    20.0 10036585 - Pregnancy, puerperium and perinatal conditions 10000154 Abnormal labour affecting foetus PT
    20.0 100000004849 10054386 Fetal heart rate disorder LLT
    20.0 10036585 - Pregnancy, puerperium and perinatal conditions 10046790 Uterine hypertonus PT
    20.0 10005329 - Blood and lymphatic system disorders 10013442 Disseminated intravascular coagulation PT
    20.0 10022117 - Injury, poisoning and procedural complications 10046820 Uterine rupture PT
    20.0 10021428 - Immune system disorders 10002198 Anaphylactic reaction PT
    20.0 100000004872 10018162 Genital oedema female LLT
    20.0 10036585 - Pregnancy, puerperium and perinatal conditions 10001971 Amniotic fluid embolism LLT
    20.0 10017947 - Gastrointestinal disorders 10028816 Nausea and vomiting LLT
    20.0 10017947 - Gastrointestinal disorders 10012735 Diarrhoea PT
    20.0 10036585 - Pregnancy, puerperium and perinatal conditions 10016492 Fetal distress syndrome LLT
    Population Age: Adolescents, Under 18, Adults Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2017-003855-47 Sponsor Protocol Number: AP301-II-002 Start Date*: 2018-02-27
    Sponsor Name:Apeptico Forschung und Entwicklung GmbH
    Full Title: Safety and preliminary efficacy of sequential multiple ascending doses of solnatide to treat pulmonary permeability oedema in patients with moderate-to-severe ARDS - a randomised, placebo-controlle...
    Medical condition: pulmonary permeability oedema in patients with moderate-to-severe ARDS
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10003083 ARDS LLT
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10037423 Pulmonary oedema PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-015168-32 Sponsor Protocol Number: D0620C00003 Start Date*: 2010-10-04
    Sponsor Name:AstraZeneca AB
    Full Title: A Multicentre, Randomised, Double Blind, Placebo controlled Phase IIb Study to compare the Efficacy and Safety of Two Dosing Regimens of Intravenous Infusions of CytoFab™ (AZD9773) in Adult Patient...
    Medical condition: Severe sepsis and/or septic shock
    Disease: Version SOC Term Classification Code Term Level
    12.1 10040047 Sepsis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) FR (Completed) ES (Completed) CZ (Completed) FI (Completed)
    Trial results: View results
    EudraCT Number: 2007-004333-42 Sponsor Protocol Number: SISPCT Start Date*: Information not available in EudraCT
    Sponsor Name:Friedrich-Schiller-University of Jena
    Full Title: Prospective randomized clinical multicenter trial about the effect of an adjunctive intravenous treatment with sodium selenite (selenase®T, double-blind) and a procalcitonin guided causal therapy (...
    Medical condition: severe sepsis / septic shock
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10040047 Sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001582-16 Sponsor Protocol Number: RF-2016-02361583 Start Date*: 2018-08-09
    Sponsor Name:FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO
    Full Title: Efficacy of Albumin Replacement and Balanced Crystalloid Solutions in Septic Shock (the ALBIOSS-BALANCED trial): a 2-by-2 factorial, investigator-initiated, open-label, multicenter, randomized, con...
    Medical condition: Septic shock
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10040070 Septic shock PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
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