Clinical trials for parkinson

The European Union Clinical Trials Register allows you to search for protocol and results information on:

interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC

clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
Clinical Trials Information System (CTIS).

The EU Clinical Trials Register currently displays 44393 clinical trials with a EudraCT protocol, of which 7405 are clinical trials conducted with subjects less than 18 years old. The register also displays information on 18700 older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).

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Trials with a EudraCT protocol (443)
Paediatric studies in scope of Art45 of the Paediatric Regulation (6)

443 result(s) found for: parkinson. Displaying page 6 of 23.

EudraCT Number: 2015-001786-10

Sponsor Protocol Number: EPI589-15-002

Start Date*: 2016-01-18

Sponsor Name:BioElectron Technology Corporation (formerly Edison Pharmaceuticals Inc.)

Full Title: A Phase 2A Safety and Biomarker Study of EPI-589 in Mitochondrial Subtype and Idiopathic Parkinson’s Disease Subjects

Medical condition: Parkinson’s disease

Disease:	Version	SOC Term	Classification Code	Term	Level
	20.0	10029205 - Nervous system disorders	10061536	Parkinson's disease	PT
	20.0	10029205 - Nervous system disorders	10061536	Parkinson's disease	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (Completed) DE (Completed)

Trial results: View results

EudraCT Number: 2010-020112-11

Sponsor Protocol Number: P07037

Start Date*: 2011-06-29

Sponsor Name:Schering-Plough Research Institute, a division of Schering Corporation

Full Title: A Phase 3, 12-Week, Double-Blind, Placebo-Controlled Efficacy and Safety Study of Preladenant in Subjects with Moderate to Severe Parkinson’s Disease. (Phase 3; Protocol No. P07037)

Medical condition: Parkinson's disease

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	14.1	10029205 - Nervous system disorders	10061536	Parkinson's disease	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: LT (Completed) LV (Completed)

Trial results: View results

EudraCT Number: 2006-002937-20

Sponsor Protocol Number: E2007-G000-309

Start Date*: 2006-12-11

Sponsor Name:Eisai Limited

Full Title: A Multi-centre, Randomised, Double-blind, Placebo- and Entacapone-controlled, Parallel Group Study of the Efficacy, Safety and Tolerability of E2007 in Levodopa Treated Parkinson's Disease Patients...

Medical condition: Parkinson's Disease

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	8.1		10013113	Disease Parkinson's	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: EE (Prematurely Ended) CZ (Prematurely Ended) LV (Prematurely Ended) LT (Prematurely Ended) IT (Completed) FR (Completed) ES (Completed) HU (Prematurely Ended)

Trial results: View results

EudraCT Number: 2009-017174-20

Sponsor Protocol Number: EMR701165_023

Start Date*: 2010-03-15

Sponsor Name:Merck Serono S.A. - Geneva

Full Title: A double-blind, randomized, placebo-controlled, parallel-group, dose escalation trial to explore the potential antidyskinetic properties of safinamide in patients with Parkinson's disease suffering...

Medical condition: Idiopathic Parkinson's disease

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	14.0	10029205 - Nervous system disorders	10061536	Parkinson's disease	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Completed) FR (Completed) AT (Completed)

Trial results: View results

EudraCT Number: 2010-020109-34

Sponsor Protocol Number: EMR701165-024

Start Date*: 2010-11-29

Sponsor Name:Merck Serono S.A. - Geneva

Full Title: Estudio Fase II, doble ciego, aleatorizado, controlado con placebo, de grupos paralelos, para explorar los posibles efectos beneficiosos de safinamida en la cognición, en pacientes no dementes co...

Medical condition: Cognition in non-demented patients with idiopathic Parkinson's disease Cognición en sujetos no dementes con Enfermedad de Parkinson idiopática

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	12.1		10061536	Parkinson's disease	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: ES (Completed) IT (Completed)

Trial results: View results

EudraCT Number: 2009-014341-84

Sponsor Protocol Number: SP0970

Start Date*: Information not available in EudraCT

Sponsor Name:Schwarz Pharma Deutschland GmbH, UCB Group

Full Title: Non-GI: A multi site, open-label, interventional Pilot study assessing the switch from oral treatment to rotigotine transdermal patch (Neupro) in Parkinson's disease patients with identified gastro...

Medical condition: idiopathic Parkinson's disease

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	12.0		10061536	Parkinson's disease	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Ongoing)

Trial results: (No results available)

EudraCT Number: 2012-000181-37

Sponsor Protocol Number: CVT-301-002

Start Date*: 2012-04-25

Sponsor Name:Civitas Therapeutics, Inc.

Full Title: A Randomized, Placebo-Controlled Phase 2 Study of the Safety, Pharmacokinetics, and Pharmacodynamics of CVT-301 (Levodopa Inhalation Powder) in Patients with Parkinson’s Disease and Motor Response ...

Medical condition: Parkinson's Disease

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	14.1	10029205 - Nervous system disorders	10034007	Parkinson's disease NOS	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (Completed)

Trial results: View results

EudraCT Number: 2009-018137-37

Sponsor Protocol Number: 09/0391

Start Date*: 2010-04-14

Sponsor Name:University College London

Full Title: An open label, single site, 12 month, Phase II, randomised controlled trial evaluating the safety and efficacy of Exendin-4 (Exenatide) in the treatment of patients with moderate severity Parkinson...

Medical condition: Parkinson's disease

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	14.1	10029205 - Nervous system disorders	10061536	Parkinson's disease	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (Completed)

Trial results: View results

EudraCT Number: 2013-001881-40

Sponsor Protocol Number: 2797

Start Date*: 2013-09-16

Sponsor Name:North Bristol NHS Trust (NBT)

Full Title: An Extension Study to Assess the Safety and Efficacy of Intermittent Bilateral Intraputamenal Glial Cell Line-Derived Neurotrophic Factor (GDNF) Infusions Administered via onvection Enhanced Delive...

Medical condition: Parkinson's disease

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	18.1	100000004852	10034008	Parkinson's syndrome	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (Completed)

Trial results: View results

EudraCT Number: 2021-004565-13

Sponsor Protocol Number: GR-2018-12366771

Start Date*: 2022-09-08

Sponsor Name:FONDAZIONE IRCCS ISTITUTO NEUROLOGICO CARLO BESTA

Full Title: Ambroxol as a disease-modifying treatment to reduce the risk of cognitive impairment in GBA-associated Parkinson's disease. A multicenter, randomized, double-blind, placebo-controlled, phase 2 trial.

Medical condition: Parkinson's disease associated to mutation on the GBA1 gene

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	100000004852	10042832	Syndrome Parkinson's	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: IT (Completed)

Trial results: (No results available)

EudraCT Number: 2016-002391-27

Sponsor Protocol Number: BIA-OPC-401

Start Date*: 2016-10-07

Sponsor Name:BIAL - Portela & Ca, S.A.

Full Title: This action will amend the information submitted in this data field for all relevant applications. Please refer to the guidance under the Amendment tab and consider whether further notification to...

Medical condition: Parkinson's disease (PD) patients with wearing-off motor fluctuations

Disease:	Version	SOC Term	Classification Code	Term	Level
	20.0	10029205 - Nervous system disorders	10061536	Parkinson's disease	PT
	20.0	10029205 - Nervous system disorders	10061536	Parkinson's disease	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (Completed) DE (Completed)

Trial results: View results

EudraCT Number: 2010-018534-44

Sponsor Protocol Number: P58/07CL/ST/09/02

Start Date*: 2010-10-22

Sponsor Name:Phytopharm plc

Full Title: A Phase II, multi-centre, randomised, double-blind, placebo-controlled, parallel group study to investigate the efficacy, safety and tolerability of Cogane™ (PYM50028), a novel, orally active neuro...

Medical condition: Early-Stage Parkinson’s Disease

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	14.1	10029205 - Nervous system disorders	10061536	Parkinson's disease	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: GB (Completed) DE (Completed) CZ (Completed) HU (Completed)

Trial results: (No results available)

EudraCT Number: 2009-014688-37

Sponsor Protocol Number: IPX066-B09-02

Start Date*: 2009-12-15

Sponsor Name:Impax Laboratories, Inc.

Full Title: A Study To Evaluate The Safety And Efficacy Of IPX066 In Advanced Parkinson’s Disease

Medical condition: Advanced Parkinson’s Disease subjects with motor fluctuations

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	12.0		10061536	Parkinson's disease	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Completed) FR (Completed) ES (Completed) PL (Completed)

Trial results: View results

EudraCT Number: 2010-018650-12

Sponsor Protocol Number: 0930303

Start Date*: 2010-07-13

Sponsor Name:CHU de Toulouse

Full Title: Evaluation du système noradrénergique dans l’altération de la perception douloureuse chez le patient Parkinsonien

Medical condition: maladie de Parkinson

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	12.1		10013113	Disease Parkinson's	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: FR (Completed)

Trial results: (No results available)

EudraCT Number: 2006-002408-32

Sponsor Protocol Number: hspbi051916

Start Date*: 2007-02-27

Sponsor Name:Institut de Recerca del Hospital de la Santa Creu i Sant Pau

Full Title: Modulación dopaminérgica de las funciones cognitivas y afectivas por el tratamiento con diferentes métodos de estimulación dopaminérgica en la enfermedad de Parkinson . Implicaciones para el tratam...

Medical condition: Fluctuaciones motoras, cognitivas y del humor en la enfermedad de Parkinson.

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	8.1		10061536	Parkinson's disease	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: ES (Ongoing)

Trial results: (No results available)

EudraCT Number: 2018-001209-95

Sponsor Protocol Number: IN18001

Start Date*: 2018-07-05

Sponsor Name:INTEC PHARMA LTD

Full Title: An open-label Phase 2 study to assess the pharmacokinetics of Accordion Pill¿ Carbidopa-Levodopa compared to immediate release carbidopa-levodopa in patients with Parkinson¿s disease

Medical condition: Parkinson's Disease (PD)

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	20.0	10029205 - Nervous system disorders	10061536	Parkinson's disease	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: IT (Completed)

Trial results: (No results available)

EudraCT Number: 2010-020299-42

Sponsor Protocol Number: KKS-135

Start Date*: 2011-08-30

Sponsor Name:Philipps-University Marburg

Full Title: A randomized, placebo-controlled, double-blind, multi-center trial to assess the disease-modifying potential of transdermal nicotine in early Parkinson's disease in Germany and the USA (NIC-PD)

Medical condition: Early PD subjects within 18 months of diagnosis and not expected to require dopamine agonist or levodopa therapy for 1 year, with Hoehn and Yahr stage <2, with stable (>2 months) MAO-B inhibitor th...

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	16.1	10029205 - Nervous system disorders	10061536	Parkinson's disease	PT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: DE (Completed)

Trial results: View results

EudraCT Number: 2021-001366-38

Sponsor Protocol Number: CCTU0263

Start Date*: 2022-10-13

Sponsor Name:Region Skåne – Skåne University Hospital

Full Title: STEM-PD trial: A multicentre, single arm, first in human, dose-escalation trial, investigating the safety and tolerability of intraputamenal transplantation of human embryonic stem cell derived dop...

Medical condition: Parkinson’s disease

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	21.1	100000004852	10013113	Disease Parkinson's	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: SE (Trial now transitioned)

Trial results: (No results available)

EudraCT Number: 2008-004943-12

Sponsor Protocol Number: S308.3.010

Start Date*: 2008-11-24

Sponsor Name:Solvay Pharmaceuticals B.V.

Full Title: The Rubens Study: A Multicenter, Randomized, Double-blind, Parallel Group, Placebo and Pramipexole Controlled Study to Explore the Efficacy, Tolerability and Safety of Different Doses and Titration...

Medical condition: Early Stage Parkinson’s Disease

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10013113	Disease Parkinson's	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: SK (Completed)

Trial results: (No results available)

EudraCT Number: 2009-011736-35

Sponsor Protocol Number: CHUBX 2009/02

Start Date*: 2009-07-27

Sponsor Name:CHU de Bordeaux

Full Title: Etude pilote de phase II, N=1 en crossover répétés, en double aveugle, randomisée versus placebo, multicentrique, évaluant l’efficacité de la SIMVAstatine sur les DYSkinésies induites par la L-Dopa...

Medical condition: Maladie de Parkinson

Disease:	Version	SOC Term	Classification Code	Term	Level
Disease:	9.1		10013113	Disease Parkinson's	LLT

Population Age: Adults, Elderly

Gender: Male, Female

Trial protocol: FR (Ongoing)

Trial results: View results

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The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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