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Clinical trials for Glaucoma

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44356   clinical trials with a EudraCT protocol, of which   7382   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    221 result(s) found for: Glaucoma. Displaying page 7 of 12.
    «« First « Previous 3  4  5  6  7  8  9  10  11  Next» Last»»
    EudraCT Number: 2022-001662-35 Sponsor Protocol Number: BTIIMD-02-EC/22/GLAUCOMA Start Date*: 2022-08-18
    Sponsor Name:BTI I MAS D S.L.
    Full Title: Randomized, double-blind, parallel group clinical trial to evaluate the efficacy and safety of PRGF eye drops as a treatment for dry eye disease in patients with glaucoma
    Medical condition: Dry eye disease in patients with glaucoma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-002078-30 Sponsor Protocol Number: RDG-11-244 Start Date*: 2012-09-10
    Sponsor Name:Alcon Research, Ltd.
    Full Title: Assessing the Efficacy and Tolerability of TRAVATAN® Solution without BAK, containing Polyquad® Preservative (travoprost 0.004%) versus LUMIGAN® 0.01% Solution with BAK (bimatoprost 0.01%) in Trea...
    Medical condition: Ocular hypertension or Open angle glaucoma
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: View results
    EudraCT Number: 2012-001324-34 Sponsor Protocol Number: C-12-008 Start Date*: 2013-03-07
    Sponsor Name:Alcon Research Ltd
    Full Title: A 3 Month, Multicenter, Double-Masked Safety and Efficacy Study of Travoprost Ophthalmic Solution, 0.004% Compared to Timolol (0.5% or 0.25%) in Pediatric Glaucoma Patients
    Medical condition: Pediatric glaucoma;elevated intraocular pressure
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed) GB (Completed) PL (Completed) DE (Completed) PT (Completed) NL (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2005-002574-29 Sponsor Protocol Number: 77550 Start Date*: 2005-08-02
    Sponsor Name:Santen Oy
    Full Title: Pharmacodynamics of tafluprost 0.0015% eye drops: a comparison between the preserved and unpreserved formulation in patients with open-angle glaucoma or ocular hypertension.
    Medical condition: Open angle glaucoma or ocular hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-001680-30 Sponsor Protocol Number: 529 Start Date*: 2007-11-02
    Sponsor Name:Bausch&Lomb Dr Gerhard Mann chem.-Fabrik GmbH
    Full Title: Randomized parallel-group, multicentre study to evaluate the after-use sensation and safety of carteolol LA 2% versus timolol LA 0.5% in simple intra-ocular hypertension and glaucoma.
    Medical condition: Adult patients suffering from unilateral or bilateral ocular hypertension or POAG, IOP controlled with beta-blocker monotherapy (IOP < 21 mmHg and visual field stable)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) PT (Completed) BE (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2009-015916-16 Sponsor Protocol Number: 2.707/03/2010 Start Date*: 2009-11-06
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust
    Full Title: A Comparison of Postural and Ibopamine Challenges between Progressive and Non-Progressive Glaucoma Patients
    Medical condition: Glaucoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-006718-10 Sponsor Protocol Number: Alcon SMA-08-16 Start Date*: 2009-08-17
    Sponsor Name:Alcon Laboratories, Inc.
    Full Title: The Efficacy and Safety of Travoprost 0.004% versus Tafluprost 0.005% in Primary Open-Angle Glaucoma or Ocular Hypertensive Patients.
    Medical condition: primary open-angle glaucoma ocular hypertension pigment dispersion glaucoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-004946-13 Sponsor Protocol Number: IIS40942 Start Date*: 2013-09-30
    Sponsor Name:University Hospitals Leuven
    Full Title: Impact of timolol/dorzolamide therapy on autoregulation in glaucoma patients
    Medical condition: Primary open-angle glaucoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-024513-31 Sponsor Protocol Number: C-10-041 Start Date*: 2011-06-15
    Sponsor Name:Alcon Research, Ltd.
    Full Title: Efficacy and Safety of Brinzolamide 10 mg/ml / Brimonidine 2 mg/ml Eye Drops, Suspension Compared to Brinzolamide 10 mg/ml Eye Drops, Suspension plus Brimonidine 2 mg/ml Eye Drops, Solution in Pati...
    Medical condition: Patients with open-angle glaucoma or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) SE (Completed) PT (Completed) HU (Completed) LT (Completed) DE (Completed) BE (Prematurely Ended) NL (Completed) AT (Completed) ES (Completed) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2013-005222-29 Sponsor Protocol Number: LT2347-PIII-12/13 Start Date*: 2014-12-19
    Sponsor Name:Laboratoires THÉA
    Full Title: Efficacy and Safety assessment of fixed combination unpreserved Latanoprost eye drops and Timolol 0.5% (T2347) versus Xalacom® in ocular hypertensive or glaucomatous patients. Phase III, internati...
    Medical condition: glaucoma, ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    17.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) BE (Completed) GB (Completed) ES (Completed) EE (Completed) HU (Completed) LV (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-005379-10 Sponsor Protocol Number: HUS_MON_2014-01 Start Date*: 2015-05-18
    Sponsor Name:Emiliano Hernández Galilea
    Full Title: Study of tear osmolarity and Quality of Life on patients treated with unpreserved latanoprost 0.005%
    Medical condition: Chronic open angle glaucoma and ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    17.1 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-000913-35 Sponsor Protocol Number: BECRO/OV/DORZO Start Date*: 2019-05-21
    Sponsor Name:BECRO (Cyprus) Ltd
    Full Title: A Randomized, Observer-blind, two Parallel Group, Multi-center, Clinical Trial for Comparing the Efficacy and Tolerability of Dorzo-Vision® sine Preservative-Free Eye Drops vs. Trusopt® Preservativ...
    Medical condition: Open angle glaucoma or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10015919 Eye disorders SOC
    20.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    20.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-000404-10 Sponsor Protocol Number: HCSC-BIMATOPROSTUD-13 Start Date*: 2015-06-10
    Sponsor Name:Hospital Clinico San Carlos
    Full Title: Effectiveness, tolerability and impact in the ocular surface of Bimatoprost and Tafluprost pods in patients with glaucoma and ocular hypertension
    Medical condition: Glaucoma andr ocular hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-000921-39 Sponsor Protocol Number: PH-BRINLOL-01 Start Date*: 2019-04-24
    Sponsor Name:PHARMATHEN SA
    Full Title: A prospective, phase III, multicenter, randomized, investigator-masked, parallel groups, non-inferiority clinical trial for the comparison of efficacy and safety and of a generic fixed combination ...
    Medical condition: open-angle glaucoma or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed) CY (Completed)
    Trial results: View results
    EudraCT Number: 2019-001642-18 Sponsor Protocol Number: WP3 Start Date*: 2019-12-05
    Sponsor Name:Department of Ophthalmology, Rigshospitalet-Glostrup
    Full Title: Effect on the ocular surface when treating glaucoma with eye drops: an investigation of the conjunctival goblet cells
    Medical condition: Open angular glaucoma and ocular hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2010-022178-14 Sponsor Protocol Number: 659 Start Date*: 2011-02-14
    Sponsor Name:Dr. Gerhard Mann Chem.-Pharm. Fabrik GmbH/Bausch & Lomb
    Full Title: A Randomized, Multicenter, Single-Masked, Parallel-Group Dose Finding Study Comparing the Safety and Efficacy of BOL-303259-X (0.006%, 0.012%, 0.024% and 0.040%) to Latanoprost 0.005% in Subjects w...
    Medical condition: Open Angle Glaucoma or Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed) CZ (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2009-018066-36 Sponsor Protocol Number: SecondLineStudy Start Date*: 2010-05-11
    Sponsor Name:Glaukos Corporation
    Full Title: Evaluación aleatorizada prospectiva en abierto del iStent® (GTS400)frente a dos agentes hipotensores oculares en pacientes con glaucoma primario de ángulo abierto
    Medical condition: Glaucoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-003979-18 Sponsor Protocol Number: LT4030-301 Start Date*: 2021-04-15
    Sponsor Name:Laboratoires THEA
    Full Title: Efficacy and Safety Assessment of T4030 Eye Drops versus Ganfort® UD in Ocular Hypertensive or Glaucomatous Patients.
    Medical condition: Primary open-angle glaucoma or Ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) PL (Completed) HU (Completed) BG (Completed) BE (Completed) ES (Ongoing) IT (Completed)
    Trial results: View results
    EudraCT Number: 2018-001855-10 Sponsor Protocol Number: SNAP1 Start Date*: 2019-01-22
    Sponsor Name:Department of Ophtalmology, Rigshospitalet-Glostrup
    Full Title: Steroids and Non-steroidal Anti-inflammatory drugs in the Postoperative regime after trabeculectomy. An investigator-initiated randomized study (The SNAP study)
    Medical condition: Medically uncontrolled glaucoma that requires filtration surgery.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004853 10018326 Glaucoma NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-004302-26 Sponsor Protocol Number: 201350 Start Date*: 2014-09-05
    Sponsor Name:Santen Oy
    Full Title: A phase I study to evaluate the pharmacokinetics, safety and tolerability of preservative free tafluprost ophthalmic solution (0.0015%) in pediatric patients diagnosed with glaucoma or ocular hyper...
    Medical condition: Glaucoma or Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    18.1 10010331 - Congenital, familial and genetic disorders 10011762 Cystic fibrosis PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed) HU (Completed) SK (Completed) PL (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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