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Clinical trials for Acute kidney failure

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    261 result(s) found for: Acute kidney failure. Displaying page 9 of 14.
    EudraCT Number: 2006-005687-44 Sponsor Protocol Number: 0468H1-316 Start Date*: 2015-04-10
    Sponsor Name:Wyeth Research
    Full Title: A Randomized, Open-Label, Comparative Evaluation of Conversion From Calcineurin Inhibitors to Sirolimus Versus Continued Use of Calcineurin Inhibitors in Renal Allograft Recipients
    Medical condition: Renal Transplantation
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2013-000819-25 Sponsor Protocol Number: 43712 Start Date*: 2013-10-22
    Sponsor Name:Leiden University Medical Center
    Full Title: Autologous BM derived MSCs in combination with everolimus to preserve renal structure and function in renal recipients
    Medical condition: renal recipients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-013220-24 Sponsor Protocol Number: Start Date*: 2009-11-02
    Sponsor Name:Addenbrooke's Hospital
    Full Title: Plasma Exchange and Glucocorticoid Dosing in the Treatment of Anti-neutrophil Cytoplasm Antibody Associated Vasculitis: an International Randomised Controlled Trial
    Medical condition: ANCA associated vasculitis
    Disease: Version SOC Term Classification Code Term Level
    12 10050894 Anti-neutrophil cytoplasmic antibody positive vasculitis LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) IT (Completed) SE (Completed) DK (Completed) CZ (Completed) ES (Completed) PL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-024381-21 Sponsor Protocol Number: CRAD001A2314 Start Date*: 2011-07-29
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A 12-month, multicenter, open label, randomized, controlled study to evaluate the efficacy, tolerability and safety of early introduction of everolimus, reduced CNI, and early steroid elimination c...
    Medical condition: Prevention of acute rejection in paediatric recipients of a renal transplant
    Disease: Version SOC Term Classification Code Term Level
    19.0 10038359 - Renal and urinary disorders 10038359 Renal and urinary disorders SOC
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: HU (Completed) BE (Completed) FR (Completed) DE (Completed) NO (Completed) IT (Completed) Outside EU/EEA SE (Completed) GB (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2005-005635-10 Sponsor Protocol Number: ATEGE_LIVER Start Date*: 2006-05-22
    Sponsor Name:Liver Unit, ICMD, Hospital Clinic Barcelona
    Full Title: INDUCTION TREATMENT FOLLOWED BY IMMUNOSUPPRESSION WITHDRAWAL IN LIVER TRANSPLANTATION: A COMPARATIVE TRIAL. Tratamiento de inducción y retirada de la inmunosupresión en el trasplante hepático. Estu...
    Medical condition: Liver transplantation
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001320-34 Sponsor Protocol Number: 2020-6384 Start Date*: 2020-04-10
    Sponsor Name:Radboudumc
    Full Title: A double-blind, placebo-controlled randomized clinical trial with valsartan for PRevention of Acute rEspiraTORy dIstress syndrome in hospitAlized patieNts with SARS-COV-2 Infection Disease
    Medical condition: SARS-CoV-2 infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended) BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-000997-39 Sponsor Protocol Number: 7837 Start Date*: 2018-03-09
    Sponsor Name:Newcastle Upon Tyne Hospitals NHS Foundation Trust
    Full Title: Eculizumab in Shiga-Toxin producing E. Coli Haemolytic Uraemic Syndrome (ECUSTEC): A Randomised, Double-Blind, Placebo-Controlled Trial
    Medical condition: Shiga-toxin producing E. Coli Haemolytic Uraemic Syndrome (STEC HUS)
    Disease: Version SOC Term Classification Code Term Level
    21.1 10005329 - Blood and lymphatic system disorders 10018932 Haemolytic uraemic syndrome PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2013-001178-20 Sponsor Protocol Number: IM103-307,SMR-2729 Start Date*: 2013-10-29
    Sponsor Name:Uppsala University Hospital, MHT, Department of Nephrology
    Full Title: Cardiovascular (CV) risk prediction and CV biomarkers in renal transplant recipients treated with belatacept compared to calcineurin inhibitors (CNI). Open randomized 12 month study.
    Medical condition: Prophylaxis of graft rejection in adults who have received a renal transplant
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004865 10050436 Prophylaxis against renal transplant rejection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DK (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2020-003603-33 Sponsor Protocol Number: SIGMA4COVID Start Date*: 2021-01-14
    Sponsor Name:Consorci Mar Parc de Salut de Barcelona
    Full Title: Efficacy of E-52862 in the early treatment of confirmed mild symptomatic COVID-19 patients
    Medical condition: Patients with mild COVID-19 disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2008-003240-11 Sponsor Protocol Number: LCP-Tacro 3001 Start Date*: 2009-02-25
    Sponsor Name:LifeCycle Pharma A/S
    Full Title: A Phase 3, Open-label, Multicenter, Prospective, Randomized Study of the Efficacy and Safety of Conversion from Prograf® Capsules Twice Daily to LCP-Tacro™ Tablets Once Daily for the Prevention of ...
    Medical condition: LCP-Tacro tablets will be investigated for immunosuppression for the prevention of acute allograft rejection in adult renal transplant patients.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10048870 Prophylaxis against transplant rejection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Completed) GB (Completed) FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-001245-13 Sponsor Protocol Number: 4LB-LEO-P Start Date*: 2022-03-03
    Sponsor Name:4Living Biotech SAS
    Full Title: A randomized, double-blind, placebo-controlled, two parallel groups, international multicenter trial to evaluate the effect of Plerixafor in acute respiratory failure related to COVID-19 (LEONARDO)
    Medical condition: Severe COVID-19
    Disease: Version SOC Term Classification Code Term Level
    23.0 10021881 - Infections and infestations 10084268 COVID-19 PT
    23.1 10021881 - Infections and infestations 10084380 COVID-19 pneumonia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) NL (Prematurely Ended) BG (Prematurely Ended) ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2020-001620-33 Sponsor Protocol Number: APHP200033 Start Date*: 2021-01-13
    Sponsor Name:ASSISTANCE-PUBLIQUE HOPITAUX DE PARIS (AP-HP)
    Full Title: HYdrocortisone and VAsopressin in Post-RESuscitation Syndrome
    Medical condition: Adult cardiac arrest patients with sustained ROSC and hemodynamic failure due to post-resuscitation syndrome
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2021-000224-35 Sponsor Protocol Number: RECEM00001 Start Date*: 2021-07-28
    Sponsor Name:Marie Kristine Jessen
    Full Title: Restrictive Fluid Administration vs. Standard of Care in Emergency Department Sepsis Patients - a Multicenter, Randomized Clinical Feasibility Trial
    Medical condition: Sepsis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10040050 Sepsis NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2017-005144-14 Sponsor Protocol Number: 01-CARDIONIDO Start Date*: 2018-04-12
    Sponsor Name:Dr. Forteza Gil
    Full Title: Comparative study of two types of cardioplegia during cardiac surgery in the adult patient
    Medical condition: Cardiac surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-023920-26 Sponsor Protocol Number: PREV-ARA Start Date*: 2011-02-09
    Sponsor Name:Fundación para la Investigación Biomédica Hospital Universitario Ramón y Cajal
    Full Title: Eficacia y seguridad del bicarbonato en el tratamiento de la alteración renal aguda asociada a la cirugía cardiaca
    Medical condition: Alteración renal aguda, término recomendado para traducir acute kidney injury que en los últimos años ha sustituido en la literatura internacional al término acute renal failure, habitualmente trad...
    Disease: Version SOC Term Classification Code Term Level
    13 10038430 Trastornos renales (excl nefropatías) HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-004549-35 Sponsor Protocol Number: CONCHAA Start Date*: 2021-05-13
    Sponsor Name:University Hospital Of Araba
    Full Title: Usefulness of the use of N-Acetylcysteine ​​associated with conventional treatment in patients with severe alcoholic hepatitis (Maddrey> = 32)
    Medical condition: Alcoholic hepatitis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-004207-32 Sponsor Protocol Number: TIKTAC-2-Trial Start Date*: 2023-04-20
    Sponsor Name:Medical University Innsbruck, Internal Medicine V
    Full Title: Daratumumab in combination with Carfilzomib, Pomalidomide and Dexamethasone (DCPD) in patients with multiple myeloma induced acute renal failure NOT requiring dialysis - “Time Is Kidney in the Trea...
    Medical condition: Multiple Myeloma: Patients with MM are frequently diagnosed primarily due to renal failure. Patients with renal failure have a poor prognosis.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-003563-38 Sponsor Protocol Number: 20140159 Start Date*: 2015-04-21
    Sponsor Name:Amgen, Inc.
    Full Title: A Multicenter Single-arm Extension Study to Characterize the Long-term Safety of Cinacalcet Hydrochloride in the Treatment of Secondary Hyperparathyroidism in Pediatric Subjects With Chronic Kidn...
    Medical condition: Secondary Hyperparathyroidism and Chronic Kidney Disease Receiving Dialysis
    Disease: Version SOC Term Classification Code Term Level
    17.1 10014698 - Endocrine disorders 10020708 Hyperparathyroidism secondary PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed) HU (Completed) CZ (Completed) ES (Completed) BE (Completed) SK (Completed) FR (Completed) Outside EU/EEA GR (Completed)
    Trial results: View results
    EudraCT Number: 2020-002871-36 Sponsor Protocol Number: VIR-7831-5001 Start Date*: 2020-11-27
    Sponsor Name:Vir Biotechnology, Inc.
    Full Title: A randomized, multi-center, double-blind, placebo-controlled study to assess the safety and efficacy of monoclonal antibody VIR-7831 for the early treatment of coronavirus disease 2019 (COVID-19) i...
    Medical condition: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection, the cause of coronavirus disease 2019 (COVID-19)
    Disease: Version SOC Term Classification Code Term Level
    23.1 10021881 - Infections and infestations 10084401 COVID-19 respiratory infection LLT
    23.0 10021881 - Infections and infestations 10084268 COVID-19 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001899-32 Sponsor Protocol Number: RESINFENOL Start Date*: 2017-08-17
    Sponsor Name:Dr. Abelardo Aguilera Peralta
    Full Title: Crossover and randomized clinical trial on the effect of Resincolestiramine in the intestinal absorption of new uremic toxins in patients in hemodialysis with chronic renal insufficiency
    Medical condition: Chronic renal insufficiency
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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