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Clinical trials for Buspirone

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    17 result(s) found for: Buspirone. Displaying page 1 of 1.
    EudraCT Number: 2011-005059-15 Sponsor Protocol Number: buspironeesostim2011 Start Date*: 2012-02-03
    Sponsor Name:uzleuven
    Full Title: The effect of Buspirone on esophageal sensitivity in healthy volunteers: a randomized, double-blind, placebo-controlled, single-dosing study.
    Medical condition: altered esophageal sensitivity, gastro-esophageal reflux disease
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2019-002182-35 Sponsor Protocol Number: buspirone2019 Start Date*: 2019-09-10
    Sponsor Name:KU Leuven - TARGID
    Full Title: The effect of oral buspirone hydrochloride on esophageal motility, bolus transit and symptoms of dysphagia, in patients with poor esophageal motility: A randomized, double-blind, placebo controlle...
    Medical condition: Patients with complaints of dysphagia and poor esophageal motility
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2014-005422-35 Sponsor Protocol Number: Start Date*: 2015-05-28
    Sponsor Name:Imperial College London-Imperial College Healthcare NHS Trust
    Full Title: THE ROLE OF BUSPIRONE IN ATTENUATING LEVODOPA-INDUCED DYSKINESIAS IN PATIENTS WITH PARKINSON'S DISEASE: A CLINICAL AND POSITRON EMISSION TOMOGRAPHY STUDY WITH 11C-PHNO.
    Medical condition: Levodopa induced dyskinesias within Parkinson's disease.
    Disease: Version SOC Term Classification Code Term Level
    17.1 10029205 - Nervous system disorders 10061536 Parkinson's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-021390-36 Sponsor Protocol Number: buspar2010 Start Date*: 2010-09-07
    Sponsor Name:uzleuven
    Full Title: The Effect of Acute Intake of Oral Buspirone Hydrochloride on Esophageal Motility, Bolus Transit and Symptoms of Dysphagia, in Patients with Ineffective Esophageal Motility: A Pilot, Open-label, Si...
    Medical condition: Ineffective Esophageal Motility
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-007580-24 Sponsor Protocol Number: EB70 Start Date*: 2008-02-08
    Sponsor Name:Emotional Brain
    Full Title: A double blind, randomized, 3-arm placebo controlled study to investigate the subjective and physiological efficacy and safety of Lybrido and Lybridos in the domestic setting in healthy female subj...
    Medical condition: Hypoactive sexual desire disorder and female sexual arousal disorder
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-016790-15 Sponsor Protocol Number: EB78 Start Date*: 2009-12-03
    Sponsor Name:Emotional Brain
    Full Title: A double blind, randomized, cross-over placebo controlled study to investigate the subjective and physiological efficacy and safety of Lybrido and Lybridos in the domestic setting in healthy female...
    Medical condition: Hypoactive Sexual Desire Disorder (comorbidity with other sexual dysfunctions e.g Female Sexual Arousal Disorder (FSAD) is allowed) and/or SSRI induced sexual dysfunctioning.
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-002735-32 Sponsor Protocol Number: EB72 Start Date*: 2008-06-24
    Sponsor Name:Emotional Brain
    Full Title: A double blind, randomized, placebo controlled cross-over study to investigate the subjective and physiological efficacy and safety of Lybrido and Lybridos in the domestic setting in healthy female...
    Medical condition: Hypoactive sexual desire disorder and female sexual arousal disorder in combination with SSRI use.
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-001966-40 Sponsor Protocol Number: CD001 Start Date*: 2014-01-27
    Sponsor Name:Companion Diagnostics BV
    Full Title: A double blind, randomized, placebo controlled, cross-over, Lybridos dose finding study to validate the predictive power of the diagnostic model for Lybrido and Lybridos efficacy and to identify an...
    Medical condition: Hypoactive Sexual Desire Disorder/SSRI-induced sexual dysfunction
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004873 10040470 Sexual desire disorders HLT
    14.1 100000004873 10020933 Hypoactive sexual desire disorder LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-007704-28 Sponsor Protocol Number: EB77 Start Date*: 2009-01-21
    Sponsor Name:Emotional Brain
    Full Title: Lybridos PoC: A double blind, randomized, cross-over placebo controlled pilot study to investigate the subjective and physiological efficacy and safety of Lybridos in healthy female subjects with F...
    Medical condition: Female Sexual Dysfunction, specifically Hypoactive Sexual Desire Disorder, with or without Female Sexual Arousal Disorder.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020933 Hypoactive sexual desire disorder LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-005383-42 Sponsor Protocol Number: BREATH Start Date*: 2016-05-19
    Sponsor Name:FONDAZIONE TOSCANA GABRIELE MONASTERIO
    Full Title: Use of buspiron in chemioreflex modulation and central apnea treatment in heart failure patients (BREATH: BuspiRon for chEmoreflex modulation and central Apnea treatment in Heart failure patients)....
    Medical condition: patient with central apneas syndrome and heart failure
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10011949 Decompensation cardiac LLT
    20.0 100000004852 10040978 Sleep apnoeas HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-003543-30 Sponsor Protocol Number: EB93 Start Date*: 2012-08-24
    Sponsor Name:Emotional Brain BV
    Full Title: A double-blind, randomized, placebo-controlled, proof of concept study to investigate the differences between the combined administration of 0.5 mg sublingual testosterone and 10 mg buspirone and 1...
    Medical condition: Hypoactive Sexual Desire Disorder Sexual Interest/Arousal Disorder
    Disease: Version SOC Term Classification Code Term Level
    14.1 10037175 - Psychiatric disorders 10037228 Psychosexual dysfunction with inhibited sexual desire LLT
    14.1 10037175 - Psychiatric disorders 10059272 Sexual desire decreased LLT
    14.1 10037175 - Psychiatric disorders 10040465 Sexual arousal decreased LLT
    14.1 10037175 - Psychiatric disorders 10058929 Disturbance in sexual arousal PT
    14.1 10037175 - Psychiatric disorders 10040470 Sexual desire disorders HLT
    14.1 10037175 - Psychiatric disorders 10040466 Sexual arousal disorders HLT
    14.1 10037175 - Psychiatric disorders 10020933 Hypoactive sexual desire disorder LLT
    14.1 10038604 - Reproductive system and breast disorders 10062641 Female sexual arousal disorder PT
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-004501-14 Sponsor Protocol Number: EDC-3135 Start Date*: Information not available in EudraCT
    Sponsor Name:ZOLL, Inc.
    Full Title: COOL-AMI EU PIVOTAL TRIAL: A MULTICENTER, PROSPECTIVE, RANDOMIZED- CONTROLLED TRIAL TO ASSESS THE SAFETY AND EFFECTIVENESS OF COOLING AS AN ADJUNCTIVE THERAPY TO PERCUTANEOUS INTERVENTION INP A TIE...
    Medical condition: Acute Myocardial Infarction
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10000891 Acute myocardial infarction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-007770-37 Sponsor Protocol Number: DP10002 Start Date*: 2009-05-29
    Sponsor Name:Acacia Pharma Ltd.
    Full Title: Randomised, double-blind, placebo-controlled, Phase II study to assess the safety and efficacy of different doses of intravenous APD405 (buspirone for IV injection) for the prevention of post-opera...
    Medical condition: Post-operative nausea and vomiting
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036901 Prophylaxis against postoperative nausea and vomiting LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2012-002944-25 Sponsor Protocol Number: EuroHyp-1 Start Date*: 2014-08-20
    Sponsor Name:Universitätsklinikum Erlangen
    Full Title: EuroHYP-1: European multicentre, randomised, phase III clinical trial of therapeutic hypothermia plus best medical treatment versus best medical treatment alone for acute ischaemic stroke
    Medical condition: Acute ischaemic stroke
    Disease: Version SOC Term Classification Code Term Level
    17.0 10029205 - Nervous system disorders 10061256 Ischaemic stroke PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) FI (Completed) IT (Completed) IE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2022-002818-16 Sponsor Protocol Number: JM-010CS-OL Start Date*: 2022-12-30
    Sponsor Name:Contera Pharma A/S
    Full Title: Open-Label Extension Study of JM-010 in Parkinson’s Disease Patients With Dyskinesia
    Medical condition: Parkinson's Disease Patients with Dyskinesia
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004852 10013113 Disease Parkinson's LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) ES (Ongoing) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-003415-19 Sponsor Protocol Number: JM-010CS03 Start Date*: 2018-10-31
    Sponsor Name:Contera Pharma
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study in Parkinson’s Disease Patients With Moderate to Severe Dyskinesia to Assess the Efficacy and Safety/Tolerability of Two Dose Co...
    Medical condition: Parkinson’s Disease Patients With Moderate to Severe Dyskinesia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Restarted) IT (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2010-021044-17 Sponsor Protocol Number: CLOCK_depression Start Date*: 2010-08-11
    Sponsor Name:Medizinische Universität Wien
    Full Title: The effect of agomelatine on CLOCK gene expression in patients with major depressive disorder and healthy controls: an exploratory study.
    Medical condition: Major depressive disorder (MDD), Seasonal affective disorder (subtype of MDD)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10012378 Depression LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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