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Clinical trials for Chronic rhinosinusitis

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    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    59 result(s) found for: Chronic rhinosinusitis. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2007-005152-16 Sponsor Protocol Number: BV-2007/04 Start Date*: 2008-10-07
    Sponsor Name:OM Pharma SA
    Full Title: Multicentre, randomised, double-blind, placebo-controlled study of the efficacy and safety of Broncho-Vaxom in adults suffering from chronic rhinosinusitis
    Medical condition: Chronic rhinosinusitis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10052106 Rhinosinusitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2011-001459-35 Sponsor Protocol Number: MC/PR/1400/007/11 Start Date*: 2012-12-20
    Sponsor Name:CHIESI
    Full Title: MULTICENTRE, RANDOMISED, DOUBLE-BLIND, PARALLEL GROUP, PLACEBO-CONTROLLED STUDY ON THE THERAPEUTIC EFFICACY AND SAFETY OF BECLOMETHASONE DIPROPIONATE SUSPENSION FOR INHALATION 800 micrograms TWICE...
    Medical condition: Acute rhinosinusitis
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004862 10052106 Rhinosinusitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-024438-52 Sponsor Protocol Number: 1-2011 Start Date*: 2011-09-05
    Sponsor Name:Fakultní nemocnice v Motole
    Full Title: Impaired sense of smell and its conservative tratment in patients with chronic rhinosinusitis
    Medical condition: The proposed clinical study on impaired sense of smell in patients with chronic rhinosinusitis.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-003896-37 Sponsor Protocol Number: BronSin2013 Start Date*: 2014-01-28
    Sponsor Name:URSAPHARM Arzneimittel GmbH
    Full Title: Efficacy and tolerability of Bromelain tablets hysan® in patients with chronic rhinosinusitis. A prospective, double-blind, randomized, placebo-controlled multi-centre trial. A proof of concept stu...
    Medical condition: Patients suffering from chronic rhinosinusitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-004226-16 Sponsor Protocol Number: ACOT 2.0 Start Date*: 2008-10-07
    Sponsor Name:Carbylan BioSurgery, Inc.
    Full Title: A prospective, multi-center, randomized, controlled, single-blinded study to evaluate the safety and efficacy of AdvaCoat Mx sinus gel for treatment of chronic rhinosinusitis without nasal polyps.
    Medical condition: Subjects with chronic rhinosinusitis without nasal polyps, who have not had previous sinus surgery might be eligible for participation in this trial.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052106 Rhinosinusitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-002738-19 Sponsor Protocol Number: ESR-17-13092 Start Date*: Information not available in EudraCT
    Sponsor Name:IRCCS ISTITUTO CLINICO HUMANITAS
    Full Title: NAsal Polyps: inflammatory & molecular Phenotyping of REsponders to Benralizumab
    Medical condition: Patients with chronic rhinosinusinusitis with nasal polyps
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10052106 Rhinosinusitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-003623-35 Sponsor Protocol Number: CRS-02 Start Date*: 2012-09-14
    Sponsor Name:Bionorica SE
    Full Title: A multicentre, randomized, double-blind, placebo-controlled, parallel group study to assess efficacy and safety of two dosages of a herbal medicinal product (dry extract BNO 1016) in patients with ...
    Medical condition: Chronic Rhinosinusitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed) DE (Completed) CZ (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2008-005828-84 Sponsor Protocol Number: ECP Start Date*: 2009-04-02
    Sponsor Name:ENT Hospital, Johannes-Gutenberg University, Mainz
    Full Title: Inflammatory mediators in nasal discharge of chronic rhinosinusitis patients treated with erythromycin.
    Medical condition: Effect of erythromycin therapy on the inflammatory mediators in nasal discharge of chronic rhinosinusitis patients.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10009137 Chronic sinusitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2013-002414-12 Sponsor Protocol Number: 12082.101 Start Date*: Information not available in EudraCT
    Sponsor Name:PARI Pharma GmbH
    Full Title: A randomised, open, controlled pilot study to investigate the efficacy and safety of Buparid/PARI SINUS versus Budes® Nasal Spray in the therapy of Chronic Rhinosinusitis (CRS) with polyposis nasi ...
    Medical condition: Chronic Rhinosinusitis (CRS) with polyposis nasi
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-017997-19 Sponsor Protocol Number: AGO/2009/014 Start Date*: 2010-08-25
    Sponsor Name:Ghent University Hospital
    Full Title: Influence of oral doxycycline on wound healing after endonasal endoscopic sinus surgery for chronic rhinosinusitis with and without nasal polyposis: a double-blind randomized placebo-controlled trial.
    Medical condition: Chronic rhinosinusitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-001682-33 Sponsor Protocol Number: GB001-2101 Start Date*: 2019-09-09
    Sponsor Name:GB001, Inc.
    Full Title: A Phase 2a, randomized, double-blind, placebo-controlled, multi-center study to evaluate the effect of GB001 in patients with chronic rhinosinusitis with or without nasal polyps
    Medical condition: Chronic Rhinosinusitis with or without Nasal Polyps
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10071399 Chronic eosinophilic rhinosinusitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2013-002421-30 Sponsor Protocol Number: 12082.102 Start Date*: 2014-06-06
    Sponsor Name:PARI Pharma GmbH
    Full Title: A randomised, open, controlled pilot study to investigate the potential of Buparid/PARI SINUS versus Budes® Nasal Spray to avoid or postpone sinus surgery in adult patients with Chronic Rhinosinu...
    Medical condition: Chronic Rhinosinusitis (CRS)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-001952-31 Sponsor Protocol Number: CRS-03 Start Date*: 2016-04-14
    Sponsor Name:Bionorica SE
    Full Title: A multicenter, randomized, double-blind, placebo-controlled, parallel-group clinical trial to assess efficacy and safety of the herbal medicinal product Sinupret extract coated tablets in patients ...
    Medical condition: Chronic rhinosinusitis
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004862 10052106 Rhinosinusitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-004377-33 Sponsor Protocol Number: 011015-01 Start Date*: 2016-04-13
    Sponsor Name:Department of Neuroscience, NTNU
    Full Title: Botulinum toxin type A Block for the sphenopalatine ganglion in chronic rhinosinusitis With nasal polyposis
    Medical condition: Chronic rhinosinusitis with nasal polyposis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-001062-14 Sponsor Protocol Number: MEC 04/265 Start Date*: 2006-02-23
    Sponsor Name:prof W.J. Fokkens, academic medical center
    Full Title: MACS Macrolides in chronic rhinosinusitis Double-blind, randomized, placebo-controlled, multinational, multicenter-trial on prolonged macrolide treatment in patients with moderate/ severe chronic...
    Medical condition: Chronic rhinosinusitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-001611-50 Sponsor Protocol Number: S67072 Start Date*: 2022-11-15
    Sponsor Name:UZ Leuven
    Full Title: Patient reported efficacy of intranasal lysine-aspirin in controlling NSAID-exacerbated respiratory disease
    Medical condition: Aspirin-Exacerbated Respiratory Disease (AERD) in patients with Chronic Rhinosinusitis with Nasal Polyps (CRSwNP)
    Disease: Version SOC Term Classification Code Term Level
    25.1 100000004855 10075084 Aspirin-exacerbated respiratory disease LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2021-000585-15 Sponsor Protocol Number: CBP-201-WW003 Start Date*: 2021-11-11
    Sponsor Name:Suzhou Connect Biopharmaceuticals Ltd.
    Full Title: A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate CBP-201 in Adult Patients with Chronic Rhinosinusitis with Nasal Polyps
    Medical condition: Chronic Rhinosinusitis with Nasal Polyps
    Disease: Version SOC Term Classification Code Term Level
    20.1 10038738 - Respiratory, thoracic and mediastinal disorders 10080060 Chronic rhinosinusitis with nasal polyps PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended) PL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-001100-11 Sponsor Protocol Number: 14/0644 Start Date*: 2018-07-13
    Sponsor Name:University College London
    Full Title: Defining best Management in Adult Chronic RhinOsinusitis
    Medical condition: Chronic rhinosinusitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10052106 Rhinosinusitis LLT
    20.1 10021881 - Infections and infestations 10009137 Chronic sinusitis PT
    20.1 10021881 - Infections and infestations 10009137 Chronic sinusitis PT
    20.1 10021881 - Infections and infestations 10009141 Chronic sinusitis, unspecified LLT
    20.0 10021881 - Infections and infestations 10031748 Other chronic sinusitis LLT
    20.1 10021881 - Infections and infestations 10009138 Chronic sinusitis, ethmoidal LLT
    20.0 10021881 - Infections and infestations 10009139 Chronic sinusitis, other LLT
    20.1 10021881 - Infections and infestations 10009140 Chronic sinusitis, sphenoidal LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2007-001435-63 Sponsor Protocol Number: NACFL-ZI-L-01-06 Start Date*: 2008-01-28
    Sponsor Name:ZAMBON ITALIA
    Full Title: AEROSOLIC TREATMENT OF ACUTE AND RECURRENT RHINOSINUSITIS DURING INTERCRITICAL STAGES : SINGLE BLIND CLINICAL STUDY, N-ACETYLCISTEIN VS AMBROXOL, ASSOCIATED WITH CORTISONE THERAPY
    Medical condition: Patients with acute recurrent rhinosinusitis(intercritical stages)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001076 Acute sinusitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2021-000829-27 Sponsor Protocol Number: LPS16747 Start Date*: 2021-09-23
    Sponsor Name:Sanofi-aventis Recherche & Développement
    Full Title: A randomized, double-blind, head-to-head comparison of dupilumab versus omalizumab in severe Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) and comorbid asthma patients
    Medical condition: Chronic rhinosinusitis with nasal polyps
    Disease: Version SOC Term Classification Code Term Level
    20.1 10038738 - Respiratory, thoracic and mediastinal disorders 10080060 Chronic rhinosinusitis with nasal polyps PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) DE (Completed) BE (Completed) CZ (Completed) FI (Completed) HU (Completed) SE (Completed) ES (Ongoing) DK (Completed) PT (Completed) PL (Completed) IT (Completed) RO (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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