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Clinical trials for Cmin

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44364   clinical trials with a EudraCT protocol, of which   7388   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    470 result(s) found for: Cmin. Displaying page 1 of 24.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2012-001142-18 Sponsor Protocol Number: GS-EMC-001 Start Date*: 2012-08-27
    Sponsor Name:Erasmus MC
    Full Title: Efficacy and pharmacokinetics of a switch from a regimen consisting of emtricitabine, nevirapine and tenofovir to rilpivirine, emtricitabine and tenofovir in virologically suppressed HIV-1 infected...
    Medical condition: HIV AIDS
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-005640-34 Sponsor Protocol Number: DFIDM-1501 Start Date*: 2016-12-29
    Sponsor Name:CHIESI FARMACEUTICI S.P.A.
    Full Title: Envarsus® tablets administered once daily in combination with everolimus in elderly de-novo kidney transplant recipients: open-label, multicentre, single-arm, pharmacokinetic and clinical study
    Medical condition: Prophylaxis of organ transplant rejection
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10050436 Prophylaxis against renal transplant rejection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2020-001655-41 Sponsor Protocol Number: 35RC19_8877_DIPLOID Start Date*: 2020-09-15
    Sponsor Name:CHU de Rennes
    Full Title: P-glypoprotein inhibition effect on the pharmacokinetics of two tacrolimus formulations: prolonged and extended-release
    Medical condition: healthy volunteers
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-004132-29 Sponsor Protocol Number: Sobi.NTBC-003 Start Date*: 2014-10-15
    Sponsor Name:Swedish Orphan Biovitrum AB (Publ)
    Full Title: An open-label, non-randomized, sequential, multicenter study to evaluate the pharmacokinetics, efficacy and safety of once daily dosing compared to twice daily dosing of Orfadin in patients diagnos...
    Medical condition: hereditary tyrosinemia type 1
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004850 10069462 Tyrosinemia type I LLT
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: SE (Completed) DK (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-000506-78 Sponsor Protocol Number: TIGE Pk 4-07 Start Date*: 2007-05-16
    Sponsor Name:Hannover Clinical Trial Center GmbH
    Full Title: Monozentrische, prospektive, offene Studie zur Untersuchung der „steady state“-Pharmakokinetik von Tigecyclin im Plasma, im ELF und in Alveolarmakrophagen bei Intensivpatienten mit tiefer Atemwegsi...
    Medical condition: Intensivpatienten mit tiefer Atemwegsinfektion
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-002695-94 Sponsor Protocol Number: RALqd-ATV Start Date*: 2008-07-21
    Sponsor Name:Fundació Lluita contra la SIDA
    Full Title: CLINICAL TRIAL ASSESSING ONCE DAILY RALTEGRAVIR ADMINISTRATION (800 mg QD) IN HIV-1-INFECTED PATIENTS RECEIVING UNBOOSTED ATAZANAVIR (400 mg QD)-BASED ANTIRETROVIRAL THERAPY (ENSAYO CLÍNICO PARA EV...
    Medical condition: Infección por VIH-1 (HIV-1 infection)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008919 Chronic HIV infection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-004854-12 Sponsor Protocol Number: N19RER Start Date*: 2019-04-12
    Sponsor Name:Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis
    Full Title: An Open-label Single-arm Pharmacokinetic Trial, Investigating the Effect of CYP3A4 inhibitor Ritonavir on the Pharmacokinetics of Erlotinib
    Medical condition: Advanced EGFR mutation positive non small cell lung cancer, pancreatic carcinoma, colorectal cancer and biliary cancer
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029522 Non-small cell lung cancer stage IV PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-022293-14 Sponsor Protocol Number: ANRS146OPTIMAL Start Date*: 2012-08-22
    Sponsor Name:Inserm-ANRS
    Full Title: Optimized Phase III Trial of Immuno-stimulation with Maraviroc, a CCR5 antagonist, combined with Anti Retroviral Therapy (cART) in advanced, Late diagnosed HIV-1 infected patients with an AIDS-defi...
    Medical condition: HIV infection
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2017-000307-24 Sponsor Protocol Number: A0031005 Start Date*: 2022-05-03
    Sponsor Name:Pfizer Inc.
    Full Title: AN OPEN LABEL NON-RANDOMIZED STUDY TO CHARACTERIZE THE STEADY STATE PHARMACOKINETICS OF SULFASALAZINE DELAYED RELEASE TABLETS IN CHILDREN WITH JUVENILE IDIOPATHIC ARTHRITIS
    Medical condition: Juvenile Idiopathic Arthritis
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2006-004982-32 Sponsor Protocol Number: LIPDEP-001 Start Date*: 2007-06-27
    Sponsor Name:Medical University of Vienna, Department of Pedatrics
    Full Title: Cerebrospinal fluid (CSF) and plasma pharmocokinetics of liposomal cytarabine (DepoCyte®) after intrathecal administration in children with malignant brain tumors and leptomeningeal dissemination
    Medical condition: To measure concentrations of liposomal cytarabine in CSF and plasma over time after intrathecal administration of liposomal cytarabine in children of different age groups with a malignant brain tum...
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2016-005252-21 Sponsor Protocol Number: N17PSI Start Date*: 2017-04-13
    Sponsor Name:Netherlands Cancer Institute
    Full Title: Increasing pazopanib exposure by splitting intake moments
    Medical condition: Patients for whom pazopanib is considered standard care (advanced renal cell carcinoma and advanced soft-tissue sarcoma).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2011-002331-25 Sponsor Protocol Number: BP27836 Start Date*: 2011-12-07
    Sponsor Name:F. Hoffmann-La Roche Ltd.
    Full Title: An Open-Label, Randomized, Multicenter Phase IIa Study Evaluating Pertuzumab in Combination with Trastuzumab and Chemotherapy in Patients with HER2-Positive Advanced Gastric Cancer
    Medical condition: HER2-positive adenocarcinoma of the stomach or gastroesophageal junction
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10066896 HER-2 positive gastric cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Completed) BE (Completed) CZ (Completed) NL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2018-004032-29 Sponsor Protocol Number: M18CYP Start Date*: 2019-01-23
    Sponsor Name:Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital
    Full Title: Effect of the moderate CYP3A4-inhibitor erythromycin on the pharmacokinetics of palbociclib
    Medical condition: Patients for whom palbociclib is standard of care (breast cancer)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2019-004417-13 Sponsor Protocol Number: CHUBX2018/65 Start Date*: 2020-06-02
    Sponsor Name:CHU de Bordeaux
    Full Title: PROSPECTIVE RANDOMIZED CLINICAL TRIAL OF EARLY OXYBUTININ TREATMENT FOR BOYS WITH POSTERIOR URETHRAL VALVES
    Medical condition: POSTERIOR URETHRAL VALVES
    Disease:
    Population Age: Infants and toddlers, Under 18 Gender: Male
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-003174-50 Sponsor Protocol Number: ALBUCEF Start Date*: 2021-01-28
    Sponsor Name:Medical University of Vienna Department of Cardiac Thoracic Vascular Anesthesia and Intensive Care Medicine
    Full Title: The Effect of Albumin Levels on Pharmacokinetics of Cefazolin in Adult Cardiac Surgery: A Prospective, Randomized, Open-label, Parallel-group Pharmacokinetic Study
    Medical condition: effect of hypoalbuminemia on pharmacokinetics of cefazolin
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2008-001605-42 Sponsor Protocol Number: 20060317 Start Date*: 2008-07-14
    Sponsor Name:Amgen Inc
    Full Title: A Multicenter, Double-Blind, 3-Arm, Phase 1b/2 Study in Subjects with Unresectable Locally Advanced or Metastatic Gastric or Esophagogastric Junction Adenocarcinoma to Evaluate the Safety and Effi...
    Medical condition: Unrespectable locally advanced or metastatic gastric or esophagogastric unction adenocarcinoma
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004864 10017759 Gastric cancer in situ LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed) IT (Prematurely Ended) GR (Completed) BE (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2010-023217-61 Sponsor Protocol Number: 10/0174 Start Date*: 2012-01-27
    Sponsor Name:University College London
    Full Title: A phase IV, open-label, partial cross-over partial parallel, randomized, multi-centre study to compare the gastrointestinal tolerability of once daily oral deferasirox, when administered before or ...
    Medical condition: transfusional haemosiderosis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10027433 - Metabolism and nutrition disorders 10019024 Haemosiderosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-001526-19 Sponsor Protocol Number: BO27798 Start Date*: 2011-12-28
    Sponsor Name:F.Hoffmann-La Roche Ltd
    Full Title: A randomized, open-label, multicenter Phase IIIb study comparing two trastuzumab dosing regimens, each in combination with cisplatin/ capecitabine chemotherapy, as first-line therapy in patients wi...
    Medical condition: Metastatic HER2-positive adenocarcinoma of the stomach or gastro-esophageal junction.
    Disease: Version SOC Term Classification Code Term Level
    16.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10071114 Metastatic gastric adenocarcinoma LLT
    16.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10063916 Metastatic gastric cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) ES (Prematurely Ended) GB (Prematurely Ended) IT (Prematurely Ended) CZ (Prematurely Ended) HU (Prematurely Ended) PT (Prematurely Ended) PL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2022-000829-24 Sponsor Protocol Number: 16 Start Date*: 2023-08-09
    Sponsor Name:ViiV Healthcare UK Limited
    Full Title: Phase 1/2 Study of Switching to Fixed Dose Combination Dolutegravir/Rilpivirine among Virologically Suppressed Children, 6 to less than 12 years of age, Living with HIV-1
    Medical condition: Virologically Suppressed Children, 6 to less than 12 years of age, Living with HIV-1
    Disease:
    Population Age: Children, Under 18 Gender:
    Trial protocol: Outside EU/EEA
    Trial results: (No results available)
    EudraCT Number: 2015-002228-25 Sponsor Protocol Number: D2615C00001 Start Date*: 2015-11-10
    Sponsor Name:AstraZeneca AB
    Full Title: An Open-Label, Randomised, Multi-Drug, Biomarker-Directed, Multi-Centre, Multi-arm Phase 1b Study in patients with Muscle Invasive Bladder Cancer (MIBC) who have progressed on prior treatment (BISCAY)
    Medical condition: Muscle-invasive bladder cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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