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Clinical trials for Heart block

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    209 result(s) found for: Heart block. Displaying page 1 of 11.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2017-002475-26 Sponsor Protocol Number: GD2CAR01 Start Date*: 2017-12-22
    Sponsor Name:IRCCS Ospedale Pediatrico Bambino Gesù
    Full Title: Phase I/II study of anti-GD2 Chimeric Antigen Receptor-Expressing T cells in pediatric patients affected by High Risk and/or relapsed/refractory Neuroblastoma
    Medical condition: High Risk and/or relapsed/refractory Neuroblastoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10019260 Heart block AV third degree LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-004178-23 Sponsor Protocol Number: T39/2021 Start Date*: 2021-04-14
    Sponsor Name:Turku University Hospital
    Full Title: Ultrasound Guided Repeated Bilateral Transversus Thoracis Muscle Plane Block (TTP) via catheter and postoperative pain in Cardiac Surgery
    Medical condition: cardiac disease necessitating surgery with sternotomy
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10046972 Valvular heart disease NOS LLT
    20.0 100000004849 10055218 Ischemic heart disease LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2014-000299-25 Sponsor Protocol Number: 1.4 Start Date*: 2014-12-05
    Sponsor Name:Unfallkrankenhaus Salzburg
    Full Title: Dexmedetomidine for saphenous nerve blockade in patients undergoing anterior cruciate ligament replacement: a randomized, placebo-controlled, triple blinded study
    Medical condition: Dexmedetomidine -a selective alpha-2-receptor agonist- added to a local anaesthetic (ropivacaine) should prolong a saphenous block and the patients demand for the first analgesic. We designed a pro...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-002519-40 Sponsor Protocol Number: CHL.2/01-2014/M Start Date*: 2015-08-17
    Sponsor Name:Sintetica S.A.
    Full Title: A prospective, randomised, non-inferiority study of Chloroprocaine 2% and the active control Ropivacaine 0.75% (AstraZeneca) in ultrasound-guided axillary nerve block for short-duration distal uppe...
    Medical condition: Local anaesthesia by axillary nerve block
    Disease: Version SOC Term Classification Code Term Level
    19.1 10042613 - Surgical and medical procedures 10024758 Local anaesthesia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2013-001287-34 Sponsor Protocol Number: BAY1067197/16718 Start Date*: 2013-11-04
    Sponsor Name:Bayer HealthCare AG
    Full Title: A single blind, placebo controlled pilot study to explore the safety and tolerability of a single oral dose of 30 mg BAY 1067197 in patients with chronic heart failure on the background of preexist...
    Medical condition: Heart failure
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004849 10019279 Heart failure LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2014-004295-28 Sponsor Protocol Number: STER-AMVR-01 Start Date*: 2014-11-14
    Sponsor Name:Oulu University Hospital, Department of Anaesthesia
    Full Title: Postoperative pain management after heart valve surgery using parasternal block and PCA Oxycodone
    Medical condition: Mitral or aortic valve disease
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004865 10049495 Heart valve operation NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-000376-28 Sponsor Protocol Number: 1245.148 Start Date*: 2018-01-30
    Sponsor Name:Boehringer Ingelheim Limited
    Full Title: A randomised, double-blind, placebo-controlled, mechanistic cardiac magnetic resonance study to investigate the effects of empagliflozin treatment on cardiac physiology and metabolism in patients w...
    Medical condition: Chronic heart failure with reduced (HFrEF) and preserved ejection fraction (HFpEF) diagnosed at least 3 months prior to informed consent.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10008908 Chronic heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-004504-29 Sponsor Protocol Number: 49024 Start Date*: 2015-02-25
    Sponsor Name:Helse Fonna, Haugesund Sykehus
    Full Title: "Haemodynamic stability of bupivacaine with and without adrenaline for paracervical block during general anesthesia. A randomized controlled double blinded study."
    Medical condition: Cervical conisation is done for pre-cancer disease. The procedure is done with local anesthesia and general anesthesia. Local anesthesia is given by paracervical block, and several different local ...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-002354-72 Sponsor Protocol Number: 1.0 Start Date*: 2013-09-05
    Sponsor Name:Medizinische Universität Wien, Universitätsklinik für Anästhesie, Allgemeine Intensivmedizin und Schmerztherapie
    Full Title: A QUALITATIVE ANALYSIS OF SEDATION IN INFANTS WITH CAUDAL BLOCKADE
    Medical condition: 34 patients aged between 0 and 3 months parted into 2 groups have to undergo caudal block. Group 1 receive a block with 1ml/kg Naropin 3.75% Group 2 receive a block with 1ml/kg Naropin 3.75% and...
    Disease:
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2010-020352-59 Sponsor Protocol Number: GHF112670 Start Date*: 2010-07-29
    Sponsor Name:GlaxoSmithKline Research & Development Limited
    Full Title: A multi-center, placebo-controlled study to evaluate the safety of GSK716155 and its effects on myocardial metabolism, myocardial function, and exercise capacity in patients with NYHA Class II/III ...
    Medical condition: NYHA Class II/III congestive heart failure.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10010684 Congestive heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-004744-38 Sponsor Protocol Number: HCA-2017-1 Start Date*: 2018-09-11
    Sponsor Name:Tays Sydänkeskus Oy
    Full Title: New truncal nerve blocks for upper torso. Part 1. Serratus anterior plane block (SAPB): Effect on pain and recovery after thoracoskopic lung surgery. Part 2. Subpectoral interfacial plane block (S...
    Medical condition: Osa 1 (SAPB): Suurin osa keuhkoleikkauksista tehdään keuhkon, keuhkopussin tai välikarsinan muutosten takia. Osa 2 (SIP): Avosydänkirurgiset läppäleikkaukset tehdään sydänläppien vuotojen, ahtaumi...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-002842-35 Sponsor Protocol Number: 2018/07 Start Date*: 2018-11-07
    Sponsor Name:CMC Ambroise Paré
    Full Title: Interest of parasternal block to prevent hypertensive and tachycardia episodes during sternotomy in patients undergoing coronary artery bypass graft
    Medical condition: coronary artery bypass graft
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10038286 Regional nerve block LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2007-000202-75 Sponsor Protocol Number: P.Sitsen.03 Start Date*: 2007-06-15
    Sponsor Name:Leids Universitair Medisch Centrum
    Full Title: A comparison of the efficacy of levobupivacaine 0,125%, ropivacaine 0,125% and ropivacaine 0,2%, all combined with sufentanil 0.5 micrograms/mL, in patient-controlled epidural analgesia after hyste...
    Medical condition: Primary Objective •to compare the analgesic efficacy of levobupivacaine and ropivacaine in patient-controlled epidural analgesia, as assessed by the number of requests for epidural bolus injections...
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-000656-18 Sponsor Protocol Number: 2042015 Start Date*: 2018-11-09
    Sponsor Name:SINTETICA SA
    Full Title: Randomized, multi-center, double-blind, two-armed, parallel active groups, prospective trial, to evaluate, in pediatric population undergoing 'Calcaneo stop' surgery or Inguinal hernia repair, the ...
    Medical condition: Pediatric patients undergoing surgery of flatfoot or inguinal hernia
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10002325 Anesthesia local LLT
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Trial now transitioned) ES (Restarted)
    Trial results: (No results available)
    EudraCT Number: 2015-001468-21 Sponsor Protocol Number: V1.0 Start Date*: 2015-09-24
    Sponsor Name:University of Oxford
    Full Title: Inhaled furosemide for dyspnoea relief in advanced heart failure
    Medical condition: Advance heart failure - New York Class Association III-IV with ejection fraction <35%.
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004849 10008908 Chronic heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-004672-35 Sponsor Protocol Number: PACS2019 Start Date*: 2020-01-10
    Sponsor Name:Institution for Clinical Science, Karolinska Institutet
    Full Title: Open heart surgery – does it have to hurt that much? PACS – Parasternal After Cardiac Surgery. A prospective randomised study to assess the analgesic effect of a continuous bilateral parasternal bl...
    Medical condition: The analgesic effect of continuous bilateral parasternal infusion of local anaesthetic after open cardiac surgery.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-001321-17 Sponsor Protocol Number: 11275 Start Date*: 2016-12-02
    Sponsor Name:University of Oxford
    Full Title: A randomised control trial of 5-Aminolevulinic Acid in combination with Sodium Ferrous Citrate to Enhance Cardioprotection in Adults undergoing Cardiac Surgery
    Medical condition: Low cardiac output states following cardioplegic arrest for cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004863 10007602 Cardiac and vascular procedural complications HLT
    19.0 10007541 - Cardiac disorders 10051624 Myocardial reperfusion injury PT
    19.0 10042613 - Surgical and medical procedures 10066123 Cardiopulmonary bypass PT
    19.0 10007541 - Cardiac disorders 10024920 Low output state LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2020-002708-38 Sponsor Protocol Number: 131313 Start Date*: 2020-10-26
    Sponsor Name:Department of Medical Science Gothenburg University
    Full Title: Optimized pharmacological treatment for broken heart (takotsubo) syndrome
    Medical condition: The medical condition is acute heart failure (Takotsubo syndrome)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-001657-27 Sponsor Protocol Number: -- Start Date*: 2018-10-03
    Sponsor Name:
    Full Title: Comparison of ultrasound guided Serratus Anterior Plane Block (SAPB) with continuous local anesthetic infusion and epidural analgesia in the treatment of multiple rib fracture analgesia: a prospect...
    Medical condition: Multiple traumatic rib fractures
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-002699-42 Sponsor Protocol Number: DANBLOCK Start Date*: 2018-09-28
    Sponsor Name:Bispebjerg Frederiksberg Hospital
    Full Title: Danish trial of beta blocker treatment after myocardial infarction without reduced ejection fraction (DANBLOCK)
    Medical condition: Myocardial infarction. We wish to test whether long-term treatment with betablocker (bisoprolol, carvedilol, metoprolol or nebivolol) leads to better prognosis than no treatment in patients sufferi...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10028595 Myocardial infarct LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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