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Clinical trials for Joint stiffness

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    184 result(s) found for: Joint stiffness. Displaying page 1 of 10.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2009-015378-36 Sponsor Protocol Number: ART1 Start Date*: 2009-12-23
    Sponsor Name:Queen Mary University of London
    Full Title: Effect of anastrozole on arthralgia and the effect of glucosamine sulphate supplementation in postmenopausal women with arthralgia in the IBIS-II breast cancer prevention trial
    Medical condition: Relief of arthralgia, joint symptoms/stiffness with glucosamine sulphate
    Disease: Version SOC Term Classification Code Term Level
    12.0 10003239 Arthralgia PT
    12.0 10023230 Joint stiffness PT
    12.0 10023226 Joint related signs and symptoms HLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-004089-16 Sponsor Protocol Number: 1541-128 Start Date*: 2013-04-03
    Sponsor Name:Universitätsklinik für Innere Medizin III, Klinische Abteilung für Rheumatologie, Medizinische Universität Wien
    Full Title: The effect of the interleukin-1 receptor antagonist Anakinra in patients with osteoarthritis of the hand: The AHOA (Anakinra in hand osteoarthritis) pilot study
    Medical condition: osteoarthritis of the hand
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-003686-17 Sponsor Protocol Number: I4V-MC-JADY Start Date*: 2013-05-29
    Sponsor Name:Eli Lilly and Company
    Full Title: A Phase 3, Multicenter Study to Evaluate the Long-Term Safety and Efficacy of Baricitinib in Patients with Rheumatoid Arthritis
    Medical condition: Rheumatoid arthritis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10039073 Rheumatoid arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) SK (Completed) CZ (Prematurely Ended) BE (Completed) PL (Completed) SE (Completed) GB (Completed) HU (Completed) AT (Completed) DK (Completed) DE (Completed) PT (Completed) NL (Completed) ES (Completed) LV (Completed) LT (Completed) GR (Completed) SI (Completed) HR (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2021-001465-20 Sponsor Protocol Number: FMLD-ARSIDOS-48 Start Date*: 2022-02-11
    Sponsor Name:Laboratorios Farmalíder S.A.
    Full Title: A double-blind, multicenter, randomized clinical trial to assess the efficacy and safety of Montelukast in patients with erosive / inflammatory arthrosis of the hands
    Medical condition: Erosive / inflammatory arthrosis of the hands
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10003416 Arthrosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Temporarily Halted)
    Trial results: (No results available)
    EudraCT Number: 2019-004641-33 Sponsor Protocol Number: DIA2020-01 Start Date*: 2021-02-16
    Sponsor Name:Diakonhjemmet Hospital
    Full Title: The Methotrexate in ERosive INflammatory Osteoarthritis (MERINO) trial
    Medical condition: Norwegian adult males and females with symptomatic erosive inflammatory hand osteoarthritis.
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004859 10016686 Finger osteoarthritis LLT
    21.1 100000004859 10019115 Hand osteoarthritis LLT
    21.0 100000004859 10064565 Erosive osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2010-024010-61 Sponsor Protocol Number: DRO/IV-ART-01 Start Date*: 2011-11-09
    Sponsor Name:BIOIBERICA, S.A.
    Full Title: NON-INFERIORITY CLINICAL TRIAL ON THE EFFICACY AND SAFETY OF CHONDROITIN SULFATE AND GLUCOSAMINE HYDROCHLORIDE IN COMBINATION VERSUS CELECOXIB IN PATIENTS WITH KNEE OSTEOARTHRITIS
    Medical condition: KNEE OSTEOARTHRITIS
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10003416 Arthrosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-019656-41 Sponsor Protocol Number: ZA/CP/0210 Start Date*: 2011-08-24
    Sponsor Name:King’s College London [...]
    1. King’s College London
    2. Guy’s and St Thomas’ NHS Foundation Trust
    Full Title: Effects of Zoledronic Acid on arterial calcification and arterial stiffness in women – a co-twin randomised double blind, placebo-controlled parallel group, clinical trial
    Medical condition: Arterial stiffness and arterial calcification
    Disease: Version SOC Term Classification Code Term Level
    14.0 10047065 - Vascular disorders 10059123 Arterial calcification LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-003994-18 Sponsor Protocol Number: EHOA Start Date*: 2008-02-18
    Sponsor Name:Leiden University Medical Center
    Full Title: EHOA: Etanercept as treatment for Hand OsteoArthritis A randomized, double-blind, placebo-controlled trial to evaluate the clinical efficacy and the structure modifying properties of etanercept 50...
    Medical condition: Patients with erosive inflammatory osteoarthritis of the interphalangeal joints
    Disease: Version SOC Term Classification Code Term Level
    9.1 10016686 Finger osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing) BE (Completed) AT (Ongoing)
    Trial results: View results
    EudraCT Number: 2015-005285-38 Sponsor Protocol Number: IM101-591 Start Date*: 2020-01-14
    Sponsor Name:The University of Leeds
    Full Title: Phase II proof of concept study of Abatacept (Orencia) in individuals who aRe Considered At risk of Developing Inflammatory Arthritis
    Medical condition: Inflammatory arthritis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10003246 Arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2007-001114-17 Sponsor Protocol Number: WA19923 Start Date*: 2007-12-12
    Sponsor Name:F. Hoffmann-La Roche Limited
    Full Title: A Mechanism of Action study to evaluate the effects of IL-6 receptor blockade with tocilizumab (TCZ) on lipids, arterial stiffness, and markers of atherogenic risk in patients with moderate to seve...
    Medical condition: Rheumatoid Arthritis (RA)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: Removed from public view
    EudraCT Number: 2014-000148-14 Sponsor Protocol Number: PLX108-10 Start Date*: 2015-06-03
    Sponsor Name:Daiichi Sankyo, Inc.
    Full Title: A Double-blind, Randomized, Placebo-controlled Phase 3 Study of Orally Administered PLX3397 in Subjects with Pigmented Villonodular Synovitis or Giant Cell Tumor of the Tendon Sheath ENLIVEN
    Medical condition: Pigmented villonodular synovitis (PVNS) / giant cell tumour of tendon sheath (GCT-TS)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10062856 Giant cell tumour of tendon sheath benign LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) DE (Completed) DK (Completed) GB (Completed) NL (Completed) ES (Temporarily Halted) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2019-004834-40 Sponsor Protocol Number: THA_glucocorticoids_Ro105 Start Date*: 2020-05-15
    Sponsor Name:University Hospitals Leuven
    Full Title: Do peri-operative high doses of intravenous glucocorticoids improve short-term functional outcome after direct anterior total hip arthroplasty? A randomized, single surgeon, placebo controlled, dou...
    Medical condition: Functional recovary after total hip arthroplasty
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-001545-25 Sponsor Protocol Number: CHDR1409 Start Date*: 2014-07-02
    Sponsor Name:Centre for Human Drug Research
    Full Title: Randomized, double-blind, placebo-controlled, three way crossover, double dummy, single centre study evaluating the effect of haloperidol 2 mg and lorazepam 1 mg on posturography and underlying sys...
    Medical condition: Healthy volunteers (balance disorders)
    Disease: Version SOC Term Classification Code Term Level
    17.0 10029205 - Nervous system disorders 10049848 Balance disorder PT
    17.0 10029205 - Nervous system disorders 10004070 Balance difficulty LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006911-60 Sponsor Protocol Number: 42801PAI3001 Start Date*: 2007-06-15
    Sponsor Name:Janssen-Cilag International N.V.
    Full Title: Randomised, double-blind, placebo-controlled, parallel-group trial to investigate the analgesic effect of OROS hydromorphone hydrochloride in comparison with placebo in subjects with moderate to se...
    Medical condition: moderate to severe pain induced by osteoarthritis of the hip or the knee
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003239 Arthralgia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) GB (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2013-005524-42 Sponsor Protocol Number: 13-1-501 Start Date*: 2015-03-10
    Sponsor Name:Reade
    Full Title: Prevention of rheumatoid arthritis by atorvastatin in seropositive arthralgia patients: a multi-center doubleblind randomized placebo-controlled trial
    Medical condition: Rheumatoid arthritis
    Disease: Version SOC Term Classification Code Term Level
    19.0 10022891 - Investigations 10039080 Rheumatoid factor positive PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-003508-36 Sponsor Protocol Number: NP01-007 Start Date*: 2008-06-17
    Sponsor Name:Nitec Pharma AG
    Full Title: A randomised multi-centre, double-blind, placebo-controlled study of a new modified-release tablet formulation of prednisolone (Lodotra®) in patients with rheumatoid arthritis
    Medical condition: Rheumatoid arthritis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039073 Rheumatoid arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) GB (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-003059-20 Sponsor Protocol Number: EMR700692_006 Start Date*: 2013-07-31
    Sponsor Name:Merck KGaA
    Full Title: A multicenter, randomized, double-blind, placebo-controlled, parallel-group trial to investigate the efficacy and safety of different intra-articular (i.a.) dosages of sprifermin in subjects with p...
    Medical condition: Primary osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) EE (Completed) DK (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2011-003232-31 Sponsor Protocol Number: TDU11685-ACT12505 Start Date*: 2011-11-03
    Sponsor Name:sanofi-aventis recherche et développement
    Full Title: A two part protocol to assess, using double blind placebo control, the safety, tolerability, and pharmacokinetics of ascending single doses of a new intra-articular administration formulation of SA...
    Medical condition: KNEE OSTEOARTHRITIS
    Disease: Version SOC Term Classification Code Term Level
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2021-000180-70 Sponsor Protocol Number: 2020-09(04) Start Date*: 2021-05-31
    Sponsor Name:Beacon Hospital
    Full Title: Knee osteoarthritis Injection Therapy (KNiT) trial
    Medical condition: Knee osteoarthritis (OA). Osteoarthritis (OA) is a debilitating disease which mostly affects people over 60 years of age. It is known to be within the top 10 contributors to years lived with disabi...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: IE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-000818-37 Sponsor Protocol Number: MTX-071-P03 Start Date*: 2018-06-28
    Sponsor Name:Grünenthal GmbH
    Full Title: A randomized, double-blind, placebo-controlled, single dose phase IIb exploratory study to document the clinical effects and safety of intra-articular injections of Lopain (MTX-071) in patients wit...
    Medical condition: chronic osteoarthritic knee joint pain
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004859 10023476 Knee osteoarthritis LLT
    20.0 100000004859 10003244 Arthritic pains LLT
    20.0 100000004859 10064238 Gonalgia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) SK (Completed) HR (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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