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Clinical trials for Middle cerebral artery

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
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    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    69 result(s) found for: Middle cerebral artery. Displaying page 1 of 4.
    1  2  3  4  Next»
    EudraCT Number: 2008-007031-41 Sponsor Protocol Number: BIAS1.0 Start Date*: 2009-09-17
    Sponsor Name:Center for Stroke Research Berlin - Charité Universitätsmedizin Berlin
    Full Title: Beta-Blocker in Acute Ischemic Stroke – a prospective, randomized, double-blinded, placebo-controlled safety and efficacy trial of early treatment
    Medical condition: Acute ischemic stroke in the A. cerebri media territory
    Disease: Version SOC Term Classification Code Term Level
    9.1 10055221 Ischemic stroke LLT
    9.1 10061256 Ischaemic stroke LLT
    9.1 10027580 Middle cerebral artery stroke LLT
    9.1 10061256 Ischaemic stroke PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-006731-31 Sponsor Protocol Number: tandem-1 Start Date*: 2008-05-19
    Sponsor Name:Fundació Institut d’Investigació en Ciències de la Salut Germans Trias i Pujol
    Full Title: Estudio doble ciego, aleatorizado, controlado con placebo de dosis escaladas de deferoxamina intravenosa en pacientes con ictus isquémico agudo tratado con activador tisular del plasminógeno. Doubl...
    Medical condition: La deferoxamina es un neuroprotector en modelos animales de isquemia/reperfusión cerebral. Si la deferoxamina es segura y bien tolerada en pacientes con ictus agudo puede significar una nueva estra...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10027580 Middle cerebral artery stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016057-17 Sponsor Protocol Number: 23349 Start Date*: 2011-07-14
    Sponsor Name:Gentofte Hospital
    Full Title: Behandling med nerveaktiverende medicin efter apopleksi - måling af genoptræningseffekt, patologisk træthed, muskelstyrke og knogleafkalkning
    Medical condition: Apopleksi.
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029205 - Nervous system disorders 10042244 Stroke LLT
    14.0 10029205 - Nervous system disorders 10048863 Hemorrhagic stroke LLT
    14.0 10029205 - Nervous system disorders 10014498 Embolic stroke PT
    14.0 10029205 - Nervous system disorders 10019016 Haemorrhagic stroke PT
    14.0 10029205 - Nervous system disorders 10027580 Middle cerebral artery stroke LLT
    14.0 10029205 - Nervous system disorders 10043647 Thrombotic stroke PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-005266-37 Sponsor Protocol Number: 1306 Start Date*: 2006-04-07
    Sponsor Name:Central Institute for Mental Health, Mannheim, Div. of Gerontopsychiatry
    Full Title: Influence of Escitalopram on the incidence of depression and dementia following acute middle cerebral artery territory infarction. A randomized, placebo-controlled, double blind study.
    Medical condition: Acute territorial infarction in the territory of the middle cerebral artery (MCA).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-005749-18 Sponsor Protocol Number: B01-02 Start Date*: 2013-08-29
    Sponsor Name:Athersys, Inc
    Full Title: Double-Blind, Randomized, Placebo-Controlled, Phase 2 Safety and Efficacy Trial of MultiStem® in Adults With Ischemic Stroke
    Medical condition: acute ischemic stroke
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004852 10055221 Ischemic stroke LLT
    14.1 100000004852 10027580 Middle cerebral artery stroke LLT
    14.1 100000004852 10042244 Stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-002079-28 Sponsor Protocol Number: 0724-018 Start Date*: 2008-10-30
    Sponsor Name:Merck & Co., Inc.
    Full Title: A Phase IIa Randomized, Double-Blind, Parallel-Groups, Placebo-Controlled Clinical Trial to Study the Efficacy and Safety of MK-0724 Intravenous Infusion on the Amelioration of Neurological Damage ...
    Medical condition: Middle cerebral artery ischemic stroke
    Disease: Version SOC Term Classification Code Term Level
    9.1 10055221 Ischemic stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-009357-22 Sponsor Protocol Number: 08/0257 Start Date*: 2009-03-09
    Sponsor Name:University College London
    Full Title: A phase IV randomised, placebo controlled, double-blind, single centre, out-patient trial to investigate the functional benefit of botulinum toxin injections combined with physiotherapy treatment f...
    Medical condition: upper limb spasticity after stroke
    Disease: Version SOC Term Classification Code Term Level
    9.1 10014498 Embolic stroke LLT
    9.1 10019016 Haemorrhagic stroke LLT
    9.1 10023027 Ischaemic stroke NOS LLT
    9.1 10027580 Middle cerebral artery stroke LLT
    9.1 10042244 Stroke LLT
    9.1 10043647 Thrombotic stroke LLT
    9.1 10048863 Hemorrhagic stroke LLT
    9.1 10055221 Ischemic stroke LLT
    9.1 10057613 Thromboembolic stroke LLT
    9.1 10061256 Ischaemic stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: Removed from public view
    EudraCT Number: 2009-012086-66 Sponsor Protocol Number: T05018-1001 Start Date*: 2009-12-01
    Sponsor Name:Grifols Inc
    Full Title: A Phase 1/2a, Open Label, Dose Escalation, Safety Study of Intra-thrombus Plasmin (Human) Administration in Acute, Middle Cerebral Artery, Ischemic Stroke
    Medical condition: Thrombus in acute ischemic stroke of the middle cerebral artery
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10008190 Cerebrovascular accident PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed) FR (Completed) SK (Completed) AT (Completed)
    Trial results: Removed from public view
    EudraCT Number: 2008-004669-24 Sponsor Protocol Number: 8103 Start Date*: 2009-01-02
    Sponsor Name:Research Innovation Services, University of Nottingham
    Full Title: Nitrous Oxide and Cerebral Autoregulation
    Medical condition: This study is being conducted to evaluate the effects of inhaled concentrations of 20%, 30% and 40% Nitrous Oxide on cerebral autoregulation in healthy volunteers using transcranial doppler ultraso...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-003870-27 Sponsor Protocol Number: RA2363 Start Date*: 2008-10-08
    Sponsor Name:University of Nottingham
    Full Title: ENOS: Efficacy of Nitric Oxide in Stroke. Estudio ENOS: Eficacia del óxido nítrico en el ictus
    Medical condition: Hipertensión en el ictus agudo
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) DK (Completed) SE (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2007-002681-34 Sponsor Protocol Number: 1 Start Date*: 2007-09-28
    Sponsor Name:St Georges Healthcare NHS Trust
    Full Title: Dual antiplatelet therapy in the acute phase following stroke and TIA; which is the best regimen?
    Medical condition: Symptomatic carotid artery stenosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007687 Carotid artery stenosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-001279-19 Sponsor Protocol Number: SONAS2018 Start Date*: 2019-08-19
    Sponsor Name:BURL Concepts, Inc.
    Full Title: Evaluation of the SONAS® ultrasound device for the assessment of bilateral cerebral perfusion in subjects with acute stroke
    Medical condition: Acute large vessel occlusion (LVO) stroke (NIHSS score: ≥ 10)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10042244 Stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2011-003470-88 Sponsor Protocol Number: 11-195 Start Date*: 2012-07-30
    Sponsor Name:University Medical Center Utrecht, The Netherlands
    Full Title: Phenylephrine versus EPhedrine on cerebral Perfusion during carotid EndarteRectomy: PEPPER study
    Medical condition: Hypotension during carotid endarterectomy
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022117 - Injury, poisoning and procedural complications 10062300 Procedural hypotension PT
    14.1 10042613 - Surgical and medical procedures 10007692 Carotid endarterectomy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-007094-23 Sponsor Protocol Number: Nitrous oxide protocol V5 Start Date*: 2008-10-09
    Sponsor Name:University of Nottingham
    Full Title: Nitrous oxide and cerebral vasodilatation: a dose-response study in healthy volunteers
    Medical condition: The study will be conducted in healthy volunteers. I will evaluate the effects of inhaled concentrations of nitrous oxide, ranging from 0% to 50%, on cerebral blood flow and cerebral vascular tone ...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2021-000939-31 Sponsor Protocol Number: JDS_2021_5 Start Date*: 2021-11-02
    Sponsor Name:Hôpital Fondation A. de Rothschild / Service de recherche clinique
    Full Title: Efficacy of dornase alfa (Pulmozyme®) on arterial recanalization in post-thrombectomy angiography in patients managed for ischemic stroke by thrombolysis and eligible for thrombectomy: a monocentri...
    Medical condition: cerebral thrombectomy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2017-002760-41 Sponsor Protocol Number: CL2-RTCCAR-001 Start Date*: 2017-09-18
    Sponsor Name:institute de Recherches Internacionales Servier (promotor internacional)
    Full Title: Assessment of Active Thrombin-Activatable Fibrinolysis Inhibitor (TAFIa) plasma kinetics in Patients at acute stage of Ischemic Stroke: Prospective, Multicentre, Open, Non-randomised, Biomarker Study
    Medical condition: Acute Ischemic Stroke
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000013700 10055221 Ischemic stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2005-001669-33 Sponsor Protocol Number: tsa1 Start Date*: 2005-12-09
    Sponsor Name:Greater Glasgow NHS Health Board / University of Glasgow co-sponsorship
    Full Title: New therapeutic targets in stroke prevention: the effect of allopurinol on the cerebral vasculature of patients with subcortical stroke
    Medical condition: Subcortical Ischaemic Stroke
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-002078-71 Sponsor Protocol Number: 16758 Start Date*: 2010-06-02
    Sponsor Name:Wilhelmina Children's Hospital/UMC Utrecht
    Full Title: Reductie van Hersenschade na “Perinatal Arterial Stroke”of PAS met recombinant humaan Erythropoietine (rhEPO): Een “Proof of Concept” en “Safety” studie
    Medical condition: treatment of perinatal stroke.
    Disease:
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2010-022874-15 Sponsor Protocol Number: 10084 Start Date*: 2010-11-08
    Sponsor Name:University of Nottingham
    Full Title: Comparison of 30% nitrous oxide with therapeutic dose nimodipine on cerebral and systemic vascular physiology
    Medical condition: This is part of a series of studies investigating the potential therapeutic use of low dose nitrous oxide in the treatment of cerebral vasospasm, a condition which occurs following brain injury and...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-005539-14 Sponsor Protocol Number: 12649A Start Date*: 2008-11-25
    Sponsor Name:H. Lundbeck A/S
    Full Title: A randomised, double-blind, parallel-group, placebo-controlled phase III study to evaluate the efficacy and safety of desmoteplase in subjects with acute ischemic stroke.
    Medical condition: Acute ischemic stroke within 3 - 9 hours after the onset of symptoms.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10055221 Ischemic stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) SE (Prematurely Ended) FI (Prematurely Ended) IE (Prematurely Ended) DK (Prematurely Ended) GB (Prematurely Ended) IT (Prematurely Ended) EE (Prematurely Ended) ES (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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