- Trials with a EudraCT protocol (3,353)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (7)
3,353 result(s) found for: Neutrophil.
Displaying page 1 of 168.
EudraCT Number: 2011-002082-38 | Sponsor Protocol Number: RG_11-123 | Start Date*: 2012-04-16 |
Sponsor Name:University of Birmingham | ||
Full Title: A study of the effects of Simvastatin on neutrophil function in elderly subjects | ||
Medical condition: We are investigating the effects of Simvastatin 80mg on neutrophil function (using in vitro studies of neutrophil function), in healthy elderly subjects as there is evidence to suggest that Simvast... | ||
Disease: | ||
Population Age: Elderly | Gender: Male, Female | |
Trial protocol: GB (Completed) | ||
Trial results: View results |
EudraCT Number: 2011-005815-10 | Sponsor Protocol Number: AJSEB001 | Start Date*: 2012-05-31 | |||||||||||||||||||||
Sponsor Name:Newcastle Upon Tyne Hospitals NHS Foundation Trust | |||||||||||||||||||||||
Full Title: Developmental Clinical Sciences: Does GM-CSF restore effective neutrophil function in critically ill patients? | |||||||||||||||||||||||
Medical condition: Complement mediated dysfunctional neutrophil phagocytosis in critical illness. | |||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||
Trial protocol: GB (Completed) | |||||||||||||||||||||||
Trial results: View results |
EudraCT Number: 2013-002341-11 | Sponsor Protocol Number: WA29049 | Start Date*: 2013-10-25 | |||||||||||
Sponsor Name:F. Hoffmann-La Roche Ltd | |||||||||||||
Full Title: A SINGLE BLIND PHASE IV PHARMACODYNAMIC STUDY TO EVALUATE NEUTROPHIL DISTRIBUTION KINETICS AND FUNCTION FOLLOWING SINGLE-DOSE TOCILIZUMAB TREATMENT IN HEALTHY SUBJECTS | |||||||||||||
Medical condition: healthy volunteers (intended indication: Rheumatoid Arthritis) | |||||||||||||
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Population Age: Elderly | Gender: Male | ||||||||||||
Trial protocol: GB (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2008-002854-39 | Sponsor Protocol Number: CAIN457A2104 | Start Date*: 2009-01-15 |
Sponsor Name:Novartis Pharma Services AG | ||
Full Title: A double blind, placebo controlled, parallel group study with an open label reference arm to assess the effects of intravenously administered AIN457 on ozone induced neutrophilia compared to placeb... | ||
Medical condition: Healthy volunteers | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: DE (Completed) | ||
Trial results: View results |
EudraCT Number: 2007-004616-31 | Sponsor Protocol Number: FR1 | Start Date*: 2008-04-11 | |||||||||||
Sponsor Name:Universitair Medisch Cemtrum Utrecht | |||||||||||||
Full Title: Prevention of neutrophil induced extracellular matrix damage following skin exposure to solar simulating radiation (SSR) | |||||||||||||
Medical condition: sunburn (erythema solaris), photoaging (elastosis solaris) | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: NL (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2015-004502-42 | Sponsor Protocol Number: UoL001145 | Start Date*: 2016-03-03 | |||||||||||
Sponsor Name:University of Liverpool | |||||||||||||
Full Title: SATURN: An exploration of the dynamic interaction between IL-17, IL-17 inhibition with (secukinumab) and neutrophils in psoriatic arthritis in vitro and ex vivo with exploratory study on the potent... | |||||||||||||
Medical condition: Psoriatic Arthritis | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2007-006276-11 | Sponsor Protocol Number: VR496/005 | Start Date*: 2008-09-01 | |||||||||||
Sponsor Name:Vectura Limited | |||||||||||||
Full Title: A Phase I/II randomised, placebo-controlled, double blind trial to assess the safety, tolerability, pharmacodynamics and exploratory efficacy of heparin 25 mg inhalation powder in patients with Cys... | |||||||||||||
Medical condition: Cystic Fibrosis | |||||||||||||
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Population Age: Adolescents, Under 18, Adults | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Completed) IE (Completed) PL (Completed) IT (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2018-001309-95 | Sponsor Protocol Number: MPH966-2-01 | Start Date*: 2018-11-30 | |||||||||||
Sponsor Name:Mereo BioPharma 4 Ltd | |||||||||||||
Full Title: A Phase 2, proof-of-concept, multicentre, double-blind, randomised, dose-ascending, sequential group, placebo-controlled study to evaluate the mechanistic effect, safety, and tolerability of 12 wee... | |||||||||||||
Medical condition: Alpha-1 antitrypsin deficiency | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) SE (Completed) DK (Completed) ES (Ongoing) PL (Completed) BE (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2012-003343-29 | Sponsor Protocol Number: RG_12-179 | Start Date*: 2013-01-18 | |||||||||||
Sponsor Name:University of Birmingham | |||||||||||||
Full Title: Simvastatin as adjuvant therapy to correct neutrophil dysfunction in older pneumonia patients - a randomised double blind placebo controlled trial | |||||||||||||
Medical condition: Acute episodes of Pneumonia and sepsis in older adults | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2020-002310-41 | Sponsor Protocol Number: “MADRID-COVID” | Start Date*: 2020-06-15 |
Sponsor Name:IIS FUNDACION JIMENEZ DIAZ | ||
Full Title: Intravenous Metoprolol in Respiratory Distress Due to COVID-19: Pilot Study "MADRID-COVID" | ||
Medical condition: The main objective of this pilot trial is to evaluate the effect of metoprolol on biological correlates of benefit of this therapy (inflammatory markers in blood and bronchoalveolar mini-lavage, mi... | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: ES (Ongoing) | ||
Trial results: (No results available) |
EudraCT Number: 2006-001859-35 | Sponsor Protocol Number: cro632 | Start Date*: 2007-04-13 | |||||||||||
Sponsor Name:Imperial College London | |||||||||||||
Full Title: Abatacept in ANCA associated vasculitis: ABAVAS | |||||||||||||
Medical condition: Anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Prematurely Ended) DE (Prematurely Ended) NL (Prematurely Ended) | |||||||||||||
Trial results: View results |
EudraCT Number: 2007-003769-41 | Sponsor Protocol Number: ALB1 | Start Date*: 2008-01-31 | |||||||||||
Sponsor Name:Medical University Graz | |||||||||||||
Full Title: Albumin in acute-on-chronic liver failure: More than just volume? A randomized, controlled study | |||||||||||||
Medical condition: Spntaneous bacterial peritonitis | |||||||||||||
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Population Age: | Gender: Male, Female | ||||||||||||
Trial protocol: AT (Completed) | |||||||||||||
Trial results: Removed from public view |
EudraCT Number: 2018-001145-14 | Sponsor Protocol Number: ALD-104 | Start Date*: 2019-04-17 | |||||||||||
Sponsor Name:bluebird bio, Inc. | |||||||||||||
Full Title: A Phase 3 Study of Lenti-D Drug Product After Myeloablative Conditioning Using Busulfan and Fludarabine in Subjects ≤17 Years of Age With Cerebral Adrenoleukodystrophy (CALD) | |||||||||||||
Medical condition: Cerebral Adrenoleukodystrophy (CALD) | |||||||||||||
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Population Age: Children, Adolescents, Under 18 | Gender: Male | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) FR (Ongoing) DE (Completed) NL (Completed) IT (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2017-001788-19 | Sponsor Protocol Number: ECS1479/2017 | Start Date*: 2018-08-24 |
Sponsor Name:Medical University Vienna | ||
Full Title: Metformin therapy to prohibit progression in patients with abdominal aortic aneurysm | ||
Medical condition: Abdominal aortic aneurysm | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: AT (Completed) | ||
Trial results: (No results available) |
EudraCT Number: 2008-000753-35 | Sponsor Protocol Number: D0520C00010 | Start Date*: 2009-02-20 | |||||||||||
Sponsor Name:AstraZeneca AB | |||||||||||||
Full Title: A Phase II, Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study to Assess the Efficacy of 28 Day Oral Administration of AZD9668 in Patients with Bronchiectasis | |||||||||||||
Medical condition: Bronchiectasis | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Completed) DK (Prematurely Ended) | |||||||||||||
Trial results: View results |
EudraCT Number: 2010-021472-28 | Sponsor Protocol Number: D3550C00014 | Start Date*: 2011-01-10 | |||||||||||
Sponsor Name:AstraZeneca AB | |||||||||||||
Full Title: A Phase II Randomised, Double-blind, Placebo-controlled, Parallel Group Study to Assess the efficacy of 28-Day Oral Administration of AZD5069 Twice Daily in Patients with Bronchiectasis. | |||||||||||||
Medical condition: Bronchiectasis | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Prematurely Ended) CZ (Prematurely Ended) | |||||||||||||
Trial results: View results |
EudraCT Number: 2016-002828-85 | Sponsor Protocol Number: RG_15-114 | Start Date*: 2017-04-28 | |||||||||||||||||||||
Sponsor Name:University of Birmingham | |||||||||||||||||||||||
Full Title: Paediatric Hepatic International Tumour Trial | |||||||||||||||||||||||
Medical condition: Hepatoblastoma and Hepatocellular Carcinoma. | |||||||||||||||||||||||
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Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Children, Adolescents, Under 18, Adults | Gender: Male, Female | ||||||||||||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) IE (Ongoing) ES (Ongoing) NO (Completed) DE (Ongoing) CZ (Ongoing) BE (Ongoing) FR (Ongoing) NL (Ongoing) PL (Ongoing) AT (Ongoing) SE (Ongoing) FI (Ongoing) | |||||||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2013-003094-10 | Sponsor Protocol Number: SPI-GCF-12-201 | Start Date*: 2014-01-16 | |||||||||||
Sponsor Name:Spectrum Pharmaceuticals | |||||||||||||
Full Title: Phase 2, Open-Label, Dose-Ranging Study of HM10460A or Pegfilgrastim use for the Management of Neutropenia in Patients with Breast Cancer who are Candidates for Adjuvant and Neoadjuvant Chemotherap... | |||||||||||||
Medical condition: Management of Neutropenia in Patients with Breast Cancer who are Candidates for Adjuvant and Neoadjuvant Chemotherapy with the Docetaxel + Cyclophosphamide (TC) Regimen | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: CZ (Completed) PL (Completed) HU (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2016-001121-14 | Sponsor Protocol Number: CL010_168 | Start Date*: Information not available in EudraCT | |||||||||||||||||||||
Sponsor Name:ChemoCentryx, Inc. | |||||||||||||||||||||||
Full Title: A Randomized, Double-Blind, Active-Controlled, Phase 3 Study to Evaluate the Safety and Efficacy of CCX168 (Avacopan) in Patients with Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculi... | |||||||||||||||||||||||
Medical condition: Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis | |||||||||||||||||||||||
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Population Age: Adolescents, Under 18, Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||
Trial protocol: IE (Completed) SE (Completed) DE (Completed) GB (Completed) AT (Completed) CZ (Completed) NL (Completed) ES (Completed) HU (Completed) DK (Completed) BE (Completed) NO (Completed) FR (Completed) IT (Completed) | |||||||||||||||||||||||
Trial results: View results |
EudraCT Number: 2010-018331-18 | Sponsor Protocol Number: ML25243 | Start Date*: 2010-05-12 | |||||||||||
Sponsor Name:F. Hoffmann-La Roche Ltd. | |||||||||||||
Full Title: A 52 week, Single center, Open-label Study to Evaluate Neutrophil function and survival effects of Tocilizumab (TCZ) in Patients with Active Rheumatoid Arthritis (RA) on Background Non-biologic DMA... | |||||||||||||
Medical condition: Adult Rheumatoid Arthritis (RA) | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Completed) | |||||||||||||
Trial results: View results |
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