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Clinical trials for Pentoxifylline

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    22 result(s) found for: Pentoxifylline. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2018-001153-27 Sponsor Protocol Number: PenVe Start Date*: 2019-02-22
    Sponsor Name:Guy's and St Thomas' NHS Foundation Trust
    Full Title: A feasibility study of a prospective randomised controlled trial comparing the use of open label pentoxifylline and tocopherol versus current standard of care for the prevention of fibrosis related...
    Medical condition: Osteoradionecrosis, trismus and dysphagia
    Disease: Version SOC Term Classification Code Term Level
    20.1 10022117 - Injury, poisoning and procedural complications 10067352 Osteoradionecrosis PT
    21.1 10028395 - Musculoskeletal and connective tissue disorders 10044684 Trismus PT
    20.0 10017947 - Gastrointestinal disorders 10013950 Dysphagia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2009-016855-23 Sponsor Protocol Number: CD09/9088 Start Date*: 2010-08-20
    Sponsor Name:University of Leeds
    Full Title: Targeting systemic inflammation to improve endothelial function in obesity
    Medical condition: Healthy volunteer trial in obese subjects (body mass index 30 or greater) in which the IMP will be used to reduce inflammation by inhibiting tumour necrosis factor(TNF)-α in order to assess the eff...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-013897-42 Sponsor Protocol Number: RHMMED0883 Start Date*: 2010-04-27
    Sponsor Name:Southampton University Hospitals NHS Trust R&D department
    Full Title: STOPAH: STeroids Or Pentoxifylline for Alcoholic Hepatitis
    Medical condition: Severe alcoholic hepatitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-002020-33 Sponsor Protocol Number: OZBS32.18194 Start Date*: 2019-12-10
    Sponsor Name:Erasmus University Medical Center
    Full Title: Pentoxifylline dose optimization in neonatal sepsis.
    Medical condition: Neonatal late onset sepsis
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004862 10053598 Late onset neonatal sepsis LLT
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing) PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-004211-31 Sponsor Protocol Number: CCR3894 Start Date*: 2014-08-20
    Sponsor Name:The Royal Marsden NHS Foundation Trust
    Full Title: Randomised double-blind controlled phase II trial of Tocovid SupraBio in combination with pentoxifylline (PTX) in patients suffering long-term adverse effects of radiotherapy for pelvic cancer
    Medical condition: Adverse effects of radiotherapy for pelvic cancer.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-024028-24 Sponsor Protocol Number: IBS-PTX Start Date*: 2012-05-30
    Sponsor Name:Hospital Universitario de Canarias
    Full Title: EFFECT OF PENTOXIFYLLINE ON THE TIGHT JUNCTIONS (TJs) OF THE INTESTINAL MUCOSA IN PATIENTS WITH IRRITABLE BOWEL SYNDROME (IBS).
    Medical condition: IRRITABLE BOWEL SYNDROME (IBS) generates tomach pain and changes in depositions number and consistency. IBS has a high prevalence in Digestive consultations. In spite of this, we haven´t good treat...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-004697-28 Sponsor Protocol Number: 523001.01.099 Start Date*: 2012-06-01
    Sponsor Name:Dr. W. Schwabe GmbH & Co. KG
    Full Title: Randomised, double-blind trial to compare the treatment effects of Ginkgo biloba extract EGb 761® and pentoxifylline in patients with sub-chronic and chronic tinnitus focussing on psycho-social pro...
    Medical condition: chronic or sub-chronic tinnitus
    Disease: Version SOC Term Classification Code Term Level
    14.1 10013993 - Ear and labyrinth disorders 10043882 Tinnitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2008-002985-70 Sponsor Protocol Number: MD-R20080507 Start Date*: 2009-04-23
    Sponsor Name:University of Magdeburg
    Full Title: Evaluation of the preventive effect of pentoxifylline and ursodeoxycholic acid to radiation induced liver toxicity after brachytherapy of liver metastases, assessed in a prospective randomised trial.
    Medical condition: Irradiation damage to the liver after HDR-brachytherapy of liver metastases.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-006168-30 Sponsor Protocol Number: RLH_Pentoxifylline_Dec2011 Start Date*: 2013-01-08
    Sponsor Name:R&D, Barts and The London NHS Trust
    Full Title: PEntoxifylline in Anaemia Resistant to erythropoietin (PEAR)
    Medical condition: We shall study patients with renal failure on dialysis. We shall particularly focus on patients with evidence of erythopoeitin stimulating agent (ESA) resistance.
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004857 10014647 End stage renal failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-006944-78 Sponsor Protocol Number: 2006/0636 Start Date*: 2007-05-11
    Sponsor Name:Centre Hospitalier Régional et Universitaire de Lille
    Full Title: Evaluation du bénéfice de survie lors de l'adjonction de pentoxifylline à la corticothérapie dans l'hépatite alcoolique sévère
    Medical condition: Etudier l'effet de l'adjonction de TORENTAL LP 400mg à la corticothérapie sur la survie à 6 mois des patients atteints d'Hépatite Alcoolique Sévère
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2022-002669-13 Sponsor Protocol Number: 87RI21_0052 Start Date*: 2022-11-25
    Sponsor Name:Limoges University Hospital
    Full Title: The PENTO protocol in Medication-related osteonecrosis of the jaw (MRONJ): a single-center phase IIa trial
    Medical condition: Medication-related osteonecrosis of the jaw (MRONJ)
    Disease: Version SOC Term Classification Code Term Level
    23.1 100000004859 10084881 Medication-related osteonecrosis of jaw LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2014-004975-22 Sponsor Protocol Number: ORN-2014-16 Start Date*: 2015-09-03
    Sponsor Name:Oral and Maxillofacial Surgery Department of Vall d'Hebron Hospital
    Full Title: Advances in the management of mandibular osteoradionecrosis: Pentoxyfilline and Tocopherol as medical treatment.
    Medical condition: Assess whether there is a clinically significant reduction in intraoral bone exposure (measured in mm) in the experimental group after the start of treatment with pentoxifylline and tocopherol (PEN...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2012-000868-15 Sponsor Protocol Number: PENT_PTA Start Date*: 2012-03-06
    Sponsor Name:UNIVERSITA' CAMPUS BIOMEDICO
    Full Title: EFFECT OF TREATMENT WITH PENTOXIFYLLINE ABOUT THE RISK RATER OF POST-angioplasty restenosis IN PATIENTS WITH LOWER LIMB arterial disease
    Medical condition: PERIPHERAL ARTERIOPATHY
    Disease: Version SOC Term Classification Code Term Level
    14.1 10047065 - Vascular disorders 10047065 Vascular disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-002548-26 Sponsor Protocol Number: 0139 Start Date*: 2020-12-16
    Sponsor Name:Royal College of Surgeons in Irlenad
    Full Title: Can Pentoxifylline improve long-term outcomes in preterm infants with late-onset sepsis or necrotizing enterocolitis? A pragmatic, randomised, placebo controlled trial
    Medical condition: Late onset sepsis & necrotising enterocolitis
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004862 10053598 Late onset neonatal sepsis LLT
    20.1 100000004856 10028884 Necrotising enterocolitis LLT
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: IE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-000618-23 Sponsor Protocol Number: ORN-01 Start Date*: 2015-05-05
    Sponsor Name:Västra Götalandsregionen/NÄL
    Full Title: Treatment of osteoradionecrosis (ORN) with pentoxifylline and α-tocopherol (PENTO)
    Medical condition: Osteoradionecrosis
    Disease: Version SOC Term Classification Code Term Level
    18.0 10028395 - Musculoskeletal and connective tissue disorders 10031264 Osteonecrosis PT
    18.0 10022117 - Injury, poisoning and procedural complications 10067352 Osteoradionecrosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-003993-42 Sponsor Protocol Number: PKB171-02 Start Date*: 2017-03-17
    Sponsor Name:Prokrea BCN S.L.
    Full Title: A multi-centre, randomised, double-blind, placebo-controlled trial to investigate the efficacy and safety of two concentrations of PKB171 against placebo in couples with asthenozoospermia who wish ...
    Medical condition: Asthenozoospermia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-000887-32 Sponsor Protocol Number: ORN-02 Start Date*: 2015-07-20
    Sponsor Name:Västra Götalandsregionen/NÄL
    Full Title: Prophylactic treatment of osteoradionecrosis (ORN) with pentoxifylline and α-tocopherol (PENTO)
    Medical condition: Osteoradionecrosis
    Disease: Version SOC Term Classification Code Term Level
    18.0 10028395 - Musculoskeletal and connective tissue disorders 10031264 Osteonecrosis PT
    18.0 10022117 - Injury, poisoning and procedural complications 10067352 Osteoradionecrosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-002042-36 Sponsor Protocol Number: CNTO148UCO2001 Start Date*: 2014-07-10
    Sponsor Name:Janssen Biologics B.V.
    Full Title: A Phase 2a Open-label Study to Evaluate Prediction of Response to Golimumab Using a Transcriptomic Profile in Subjects with Moderately to Severely Active Ulcerative Colitis
    Medical condition: Moderately to Severely Active Ulcerative Colitis
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004856 10045365 Ulcerative colitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) HU (Completed) CZ (Completed) BG (Completed) PL (Completed) DE (Completed) NL (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2011-004091-12 Sponsor Protocol Number: 1204-01 Start Date*: 2013-01-07
    Sponsor Name:Pluristem Ltd.
    Full Title: A Phase II, Randomized, Double-Blind, Multicenter, Multinational, Placebo-Controlled, Parallel-Groups Study to Evaluate the Safety and Efficacy of Intramuscular Injections of Allogeneic PLX-PAD Cel...
    Medical condition: Intermittent Claudication (IC); Fontaine class IIb; Rutherford category 2-3
    Disease: Version SOC Term Classification Code Term Level
    17.1 10047065 - Vascular disorders 10022562 Intermittent claudication PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-005985-10 Sponsor Protocol Number: PTF-REN-001 Start Date*: 2008-03-03
    Sponsor Name:Juan Francisco Navarro González
    Full Title: Análisis del Efecto Renoprotector de la Pentoxifilina en Pacientes con Enfermedad Renal Crónica Secundaria a Nefropatía Diabética
    Medical condition: Enfermedad renal crónica secundaria a nefropatía diabética.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061835 Diabetic nephropathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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