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Clinical trials for Perampanel

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    22 result(s) found for: Perampanel. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2017-001180-20 Sponsor Protocol Number: E2007-G000-410 Start Date*: 2021-10-28
    Sponsor Name:Eisai Inc.
    Full Title: Multicenter, Open-Label Study to Evaluate the Efficacy and Safety of Perampanel as Monotherapy or First Adjunctive Therapy in Subjects With Partial Onset Seizures With or Without Secondarily Genera...
    Medical condition: Epilepsy: Partial Onset Seizures with or without 1) Secondarily Generalized Seizures 2) Primary Generalized Tonic-Clonic Seizures
    Disease: Version SOC Term Classification Code Term Level
    24.0 10029205 - Nervous system disorders 10085326 Parietal lobe epilepsy PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2016-004945-10 Sponsor Protocol Number: E2007-J000-341 Start Date*: 2017-08-30
    Sponsor Name:Eisai Co., ltd
    Full Title: An Open-label Extension Study to Evaluate the Safety and Tolerability of Perampanel (E2007) Administered as an Adjunctive Therapy in Epilepsy Subjects
    Medical condition: Epilepsy
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2014-002321-35 Sponsor Protocol Number: E2007-G000-338 Start Date*: 2017-05-08
    Sponsor Name:Eisai Limited
    Full Title: A Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial With an Open-Label Extension Phase of Perampanel as Adjunctive Treatment in Subjects at Least 2 years of Age With Inadequately Cont...
    Medical condition: Seizures associated with Lennox-Gastaut Syndrome (LGS)
    Disease: Version SOC Term Classification Code Term Level
    19.1 10029205 - Nervous system disorders 10048816 Lennox-Gastaut syndrome PT
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) BE (Prematurely Ended) LV (Prematurely Ended) PL (Prematurely Ended) CZ (Completed) FR (Prematurely Ended) IT (Completed)
    Trial results: View results
    EudraCT Number: 2018-004456-38 Sponsor Protocol Number: E2007-G000-236 Start Date*: 2019-10-31
    Sponsor Name:Eisai Limited
    Full Title: An Open-Label Study with Extension Phase to Evaluate the Efficacy and Safety of Perampanel Administered as an Adjunctive Therapy in Pediatric Subjects (Age 1 Month to Less Than 18 Years) With Child...
    Medical condition: Seizures associated with paediatric epilepsy syndromes and partial-onset seizures
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029205 - Nervous system disorders 10015037 Epilepsy PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: CZ (Prematurely Ended) FR (Trial now transitioned) DE (Trial now transitioned) DK (Completed) BE (Trial now transitioned) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-018518-56 Sponsor Protocol Number: E2007-G000-235 Start Date*: 2010-10-11
    Sponsor Name:Eisai Limited
    Full Title: A Randomized, Double-blind, Placebo-controlled, Parallel-group Study With an Open-label Extension Phase to Evaluate the Effect of Perampanel (E2007) on Cognition, Growth, Safety, Tolerability, and ...
    Medical condition: Inadequately controlled partial onset seizures
    Disease:
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: LV (Completed) ES (Completed) BE (Completed) HU (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2020-002109-24 Sponsor Protocol Number: E2007-J000-335 Start Date*: 2020-06-17
    Sponsor Name:Eisai Co., Ltd.
    Full Title: A Double-blind, Placebo-controlled, Parallel-group Study With an Openlabel Extension Phase to Evaluate the Efficacy and Safety of Perampanel (E2007) Administered as an Adjunctive Therapy in Subject...
    Medical condition: Refractory Partial-onset Seizures
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029205 - Nervous system disorders 10015037 Epilepsy PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2007-006170-28 Sponsor Protocol Number: E2007-G000-307 Start Date*: 2008-09-15
    Sponsor Name:Eisai Ltd
    Full Title: An Open-Label Extension Phase of the Double-Blind, Placebo-Controlled, Dose-scalation, Parallel-Group Studies to Evaluate the Efficacy and Safety of E2007 (perampanel) Given as Adjunctive Therapy i...
    Medical condition: Epilepsy: refractory partial seizures with or without secondary generalisation
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) ES (Completed) AT (Completed) BE (Completed) PT (Completed) LT (Completed) NL (Completed) HU (Completed) FR (Completed) GB (Completed) SE (Completed) EE (Completed) LV (Completed) DK (Completed) IT (Completed) DE (Completed) FI (Completed) BG (Prematurely Ended) GR (Completed)
    Trial results: View results
    EudraCT Number: 2013-005391-17 Sponsor Protocol Number: E2007-G000-238 Start Date*: 2016-09-22
    Sponsor Name:Eisai Limited
    Full Title: An Open-Label Study With an Extension Phase to Evaluate the Pharmacokinetics of Perampanel (E2007) Oral Suspension When Given as an Adjunctive Therapy in Subjects From 1 Month to Less Than 4 years ...
    Medical condition: This study is to investigate the pharmacokinetics (PK) of perampanel in pediatric subjects from age ≥1 month to <4 years.
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: LV (Completed)
    Trial results: View results
    EudraCT Number: 2019-003734-17 Sponsor Protocol Number: E2007-J000-342 Start Date*: 2019-11-22
    Sponsor Name:Eisai Co., Ltd. (Japan)
    Full Title: A Multicenter, Uncontrolled, Open-label Study and Extension Study for Verification of Efficacy and Safety for Perampanel Monotherapy in Untreated Patients with Partial Onset Seizures (Including Sec...
    Medical condition: Epilepsy : 1) Partial-Onset Seizures (POS)
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029205 - Nervous system disorders 10015037 Epilepsy PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2014-002167-16 Sponsor Protocol Number: E2007-G000-311 Start Date*: 2017-01-30
    Sponsor Name:Eisai Limited
    Full Title: An Open-Label, Multicenter Study with an Extension Phase to Evaluate the Safety, Tolerability, and Exposure-Efficacy Relationship of Perampanel Oral Suspension when Administered as an Adjunctive Th...
    Medical condition: Epilepsy : 1) Partial-Onset Seizures (POS) 2) Primary Generalized Tonic-Clonic Seizures (PGTC)
    Disease: Version SOC Term Classification Code Term Level
    19.0 10029205 - Nervous system disorders 10018101 Generalised tonic-clonic seizures HLT
    19.0 10029205 - Nervous system disorders 10061334 Partial seizures PT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: HU (Completed) LV (Completed) ES (Completed) PL (Completed) BE (Completed) IT (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2011-001105-28 Sponsor Protocol Number: E2007-G000-232 Start Date*: 2016-06-27
    Sponsor Name:Eisai Inc.
    Full Title: An Open-label Pilot Study With an Extension Phase to Evaluate the Pharmacokinetics, and to Generate Preliminary Safety, Tolerability, and Efficacy of Perampanel (E2007) Oral Suspension When Given a...
    Medical condition: Epilepsy
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2021-001839-77 Sponsor Protocol Number: 5mille_CT1 Start Date*: 2022-04-26
    Sponsor Name:IRCCS MATERNO INFANTILE BURLO GAROFOLO
    Full Title: A Multicentric, Drug-Repositioning, Self Controlled Case Series (SCCS) Clinical Trial to Evaluate the Efficacy and Safety of Perampanel in Improving Behavioral Symptoms and Increasing the Quality o...
    Medical condition: Patients with POGZ related disorder
    Disease: Version SOC Term Classification Code Term Level
    20.0 10037175 - Psychiatric disorders 10037173 Psychiatric and behavioural symptoms NEC HLGT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-000265-12 Sponsor Protocol Number: E2007-G000-332 Start Date*: 2011-08-31
    Sponsor Name:Eisai Limited
    Full Title: A Double-blind, Randomized, Placebo-controlled, Multicenter, Parallel-group Study with an Open-label Extension Phase to Evaluate the Efficacy and Safety of Adjunctive Perampanel in Primary Generali...
    Medical condition: Primary Generalized Tonic-Clonic Seizures
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10018101 Generalised tonic-clonic seizures HLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) DE (Completed) LV (Completed) GR (Completed) AT (Completed) CZ (Completed) NL (Completed) PL (Completed) LT (Completed)
    Trial results: View results
    EudraCT Number: 2019-000882-19 Sponsor Protocol Number: P160949J Start Date*: 2020-07-15
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Efficacy of add-on PEramPanel in focal motor Status epilepticus
    Medical condition: Patients with a focal motor status epilepticus
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-005495-13 Sponsor Protocol Number: E2007-G000-228 Start Date*: 2008-03-26
    Sponsor Name:Eisai Limited
    Full Title: A Multi-Center, Open-Label Extension Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of E2007 (Perampanel) in Patients with Painful Diabetic Neuropathy (PDN) or Post-Herpetic Neu...
    Medical condition: Painful Diabetic Neuropathy (Painful Herpetic Neuralgia will not be studied in the EU as the preceding double-blind study was not conducted here)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012680 Diabetic neuropathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) DE (Completed) LT (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-006191-11 Sponsor Protocol Number: E2007-G000-304 Start Date*: 2017-02-13
    Sponsor Name:Eisai Inc.
    Full Title: A Double-Blind, Placebo-Controlled, Dose-Escalation, Parallel-Group Study to Evaluate the Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refractory Partial S...
    Medical condition: Refractory Partial Seizures
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2007-006169-33 Sponsor Protocol Number: E2007-G000-306 Start Date*: 2008-07-17
    Sponsor Name:Eisai Ltd
    Full Title: Estudio doble ciego, controlado con placebo, con aumento gradual de dosis, en grupos paralelos para evaluar la eficacia y la seguridad de E2007 (perampanel) administrado como terapia adyuvante en p...
    Medical condition: Epilepsia: crisis parciales refractarias con o sin crisis secundarias generalizadas Epilepsy - refractory partial seizures with or without secondary generalisation
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) CZ (Completed) PT (Completed) HU (Completed) EE (Completed) LT (Completed) PL (Completed) LV (Completed) IT (Completed) BG (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-006168-31 Sponsor Protocol Number: E2007-G000-305 Start Date*: 2008-08-28
    Sponsor Name:Eisai Ltd
    Full Title: A Double-Blind, Placebo-Controlled, Dose-Escalation, Parallel-Group Study to Evaluate the Efficacy and Safety of E2007 (perampanel) Given as Adjunctive Therapy in Subjects with Refractory Partial S...
    Medical condition: Epilepsy: refractory partial seizures with or without secondary generalisation
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) BE (Completed) NL (Completed) DE (Completed) FR (Completed) SE (Completed) GB (Completed) DK (Completed) FI (Completed) IT (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2005-004293-24 Sponsor Protocol Number: E2007-A001-207 Start Date*: 2006-09-26
    Sponsor Name:Eisai Limited
    Full Title: An Open-label Extension Phase of the Double-blind, Placebo-controlled, Dose-escalation, Parallel-group Study of E2007 (perampanel) as an Adjunctive Therapy in Patients With Refractory Partial Seizu...
    Medical condition: E2007 is given as adjunctive, long-term treatment in patients with refractory partial onset seizures with or without secondary generalization
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) LT (Completed) DE (Completed) CZ (Completed) GB (Completed) ES (Completed) LV (Completed) BE (Completed) FI (Completed) EE (Completed) FR (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2006-006488-22 Sponsor Protocol Number: E2007-G000-227 Start Date*: 2007-10-03
    Sponsor Name:Eisai Limited
    Full Title: A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel- Group Trial to Evaluate the Efficacy and Safety of E2007 in Patients with Painful Diabetic Neuropathy
    Medical condition: Painful Diabetic Neuropathy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012680 Diabetic neuropathy LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed) LT (Completed) DE (Completed) GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
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