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Clinical trials for Perioperative period

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    120 result(s) found for: Perioperative period. Displaying page 1 of 6.
    1  2  3  4  5  6  Next»
    EudraCT Number: 2017-000043-40 Sponsor Protocol Number: GLOBE2017 Start Date*: 2017-04-24
    Sponsor Name:Academic Medical Center
    Full Title: GLP-1 for bridging of hyperglycaemia during cardiac surgery: a randomized controlled trial
    Medical condition: Hyperglyceamia during Cardiac Surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004861 10060439 Stress induced hyperglycaemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2004-005136-76 Sponsor Protocol Number: ASINC101C Start Date*: 2005-05-02
    Sponsor Name:Professor Christina Eintrei,Institution of Medical & Health, Section of Anesthesiology
    Full Title: Aspirin in noncardiac surgery
    Medical condition: Patients with cardiovascular risk factors undergoing elective non-cardiac surgery of high or intermediate risk.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-001315-31 Sponsor Protocol Number: GD032011 Start Date*: 2011-09-21
    Sponsor Name:University Hospitals Leuven
    Full Title: analgesia with continuous IV-infusion of lidocain during the perioperative period in patients undergoin laparoscopic sterilization.
    Medical condition: postoperative pain
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2022-001184-28 Sponsor Protocol Number: PeP-RALP Start Date*: 2022-10-11
    Sponsor Name:Oslo University Hospital
    Full Title: Perioperative Propranolol in Robotic Assisted Laparoscopic Prostatectomy - A Pilot Study A parallel-group, phase 2, double-blind, 2-arm study to assess the feasibility of conducting a formal large...
    Medical condition: Prostate Cancer
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-002725-23 Sponsor Protocol Number: FPS-ROP-2021-03 Start Date*: 2021-11-18
    Sponsor Name:Fundación Pública Andaluza Progreso y Salud
    Full Title: ULTRASOUND-GUIDED ERECTOR SPINAE BLOCKADE AS PART OF MULTIMODAL ANALGESIA IN LUMBOSACRAL SURGERY: A PROSPECTIVE RANDOMISED STUDY.
    Medical condition: Pain in lumbosacral surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-004552-37 Sponsor Protocol Number: 18CH052 Start Date*: 2019-05-07
    Sponsor Name:CHU SAINT-ETIENNE
    Full Title: Dose Study of Tranexamic Acid in Total Hip Replacement to Reduce Postoperative Hemoglobin Loss. A Phase 2 Randomized Double-blind Monocentric Study
    Medical condition: Arthropathy of Hip
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10077058 Hip arthropathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-003808-39 Sponsor Protocol Number: MK-3475-866 Start Date*: 2019-07-01
    Sponsor Name:Merck Sharp & Dohme LLC
    Full Title: A Phase 3, Randomized Double Blind Study to Evaluate Peri-operative Pembrolizumab (MK-3475) + Neoadjuvant Chemotherapy versus Perioperative Placebo + Neoadjuvant Chemotherapy in Cisplatin-Eligible ...
    Medical condition: Muscle Invasive Bladder Cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10005003 Bladder cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Trial now transitioned) IE (Trial now transitioned) DE (Trial now transitioned) GB (GB - no longer in EU/EEA) DK (Trial now transitioned) BE (Trial now transitioned) HU (Trial now transitioned) ES (Ongoing) PL (Trial now transitioned) FR (Trial now transitioned) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-003809-26 Sponsor Protocol Number: MK-3475-905 Start Date*: 2019-07-01
    Sponsor Name:Merck Sharp & Dohme LLC
    Full Title: A Randomized Phase 3 Study Evaluating Cystectomy with Perioperative Pembrolizumab and Cystectomy with Perioperative Enfortumab Vedotin and Pembrolizumab versus Cystectomy Alone in Participants who ...
    Medical condition: Muscle-invasive Bladder Cancer (MIBC)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004864 10022877 Invasive bladder cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Trial now transitioned) GB (GB - no longer in EU/EEA) IE (Trial now transitioned) DK (Trial now transitioned) HU (Trial now transitioned) DE (Trial now transitioned) BE (Trial now transitioned) ES (Ongoing) PL (Trial now transitioned) FR (Trial now transitioned) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2010-022417-25 Sponsor Protocol Number: NL 33608 Start Date*: 2011-04-18
    Sponsor Name:University Medical Center Groningen
    Full Title: Pheochromocytoma RandomisEd Study Comparing adRenoreceptor Inhibiting agents for Preoperative Treatment
    Medical condition: Perioperative hemodynamic control in patients undergoing resection of a pheochromocytoma
    Disease: Version SOC Term Classification Code Term Level
    12.1 10034876 Pheochromocytoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-003595-11 Sponsor Protocol Number: 2004-06-DP-119-RKF-25 Start Date*: 2005-03-18
    Sponsor Name:Canadian Cardiovascular Collaboration, Population Health Research Institute, McMaster University
    Full Title: PeriOperative ISchemic Evaluation study
    Medical condition: Perioperative cardiac events frequently complicate non-cardiac surgery resulting in significant morbidity, mortality and cost. There is no clear evidence from RCTs on how to lower perioperative ca...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-003106-31 Sponsor Protocol Number: MK-3475-B15 Start Date*: 2021-04-27
    Sponsor Name:Merck Sharp & Dohme LLC
    Full Title: A Phase 3, Randomized, Open-label Study to Evaluate Perioperative Enfortumab Vedotin Plus Pembrolizumab (MK-3475) Versus Neoadjuvant Gemcitabine and Cisplatin in Cisplatin-eligible Participants wit...
    Medical condition: Urothelial Carcinoma and Muscle Invasive Bladder Cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10064467 Urothelial carcinoma LLT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10005003 Bladder cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned) FR (Trial now transitioned) PL (Trial now transitioned) CZ (Trial now transitioned) PT (Trial now transitioned) GR (Trial now transitioned) BG (Trial now transitioned) IT (Trial now transitioned) RO (Trial now transitioned) HU (Trial now transitioned) HR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2019-002023-15 Sponsor Protocol Number: EFC16293 Start Date*: 2020-02-25
    Sponsor Name:Bioverativ Therapeutics Inc. (a Sanofi company)
    Full Title: Phase 3 Open-Label, Multicenter Study of the Safety, Efficacy, and Pharmacokinetics of Intravenous Recombinant Coagulation Factor VIII Fc-von Willebrand Factor-XTEN Fusion Protein (rFVIIIFc-VWF-XTE...
    Medical condition: severe hemophilia A
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10016080 Factor VIII deficiency PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (GB - no longer in EU/EEA) FR (Completed) BG (Completed) BE (Completed) GR (Completed) HU (Completed) NL (Completed) ES (Completed) Outside EU/EEA IT (Completed)
    Trial results: View results
    EudraCT Number: 2011-004733-14 Sponsor Protocol Number: GSKET102011 Start Date*: 2012-03-22
    Sponsor Name:Medizinische Universität Wien
    Full Title: Intravenous S-Ketamine as an Analgesic Adjunct to General Anesthesia in chronic opioid-tolerant patient
    Medical condition: In the present investigation, we will compare the perioperative subanesthetic infusion of ketamine with placebo in opioid-resistant patients undergoing major orthopedic surgery. By powering the stu...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-005521-39 Sponsor Protocol Number: 241502 Start Date*: 2016-06-20
    Sponsor Name:Baxalta Innovations GmbH
    Full Title: A Phase 3, Multicenter, Single-arm, Open-label Study of the Efficacy and Safety of B-Domain Deleted Recombinant Porcine Factor VIII (BAX 802) in Subjects with Congenital Hemophilia A with Factor VI...
    Medical condition: Congenital Haemophilia A with Factor VIII Inhibitors
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004850 10053751 Hemophilia A with anti factor VIII LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male
    Trial protocol: GB (GB - no longer in EU/EEA) ES (Prematurely Ended) NL (Prematurely Ended) PL (Prematurely Ended) DE (Prematurely Ended) NO (Prematurely Ended) BG (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-020332-19 Sponsor Protocol Number: Prot-22121988-2010 Start Date*: 2010-08-23
    Sponsor Name:ERASMUS MC, Dept Anesthesiology
    Full Title: Putting Resistance under the Microscope. (Weerstand onder de Loep)
    Medical condition: Patients resistance concerning diagnostic or therapeutic procedure are well known. In this trial patients-resistance during the perioperative period will be investigated in day-case-surgery. Feat...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10002865 Anxiety reaction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-013228-21 Sponsor Protocol Number: Start Date*: 2010-07-06
    Sponsor Name:University of Oxford
    Full Title: Prevention of atrial oxidative stress and electrical remodelling in patients undergoing cardiac surgery: randomised placebo-controlled trial of perioperative high-dose atorvastatin
    Medical condition: POST-OPERATIVE ATRIAL FIBRILLATION
    Disease: Version SOC Term Classification Code Term Level
    13 10003658 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2019-003795-39 Sponsor Protocol Number: TKADEX Start Date*: 2020-12-15
    Sponsor Name:Turku University Hospital
    Full Title: Premedication with intranasal dexmedetomidine in sedation of patients undergoing total knee arthroplasty (TKADEX) - a prospective, double blinded randomized controlled trial
    Medical condition: Knee arthrosis
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004859 10031165 Osteoarthritis knee LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-000769-18 Sponsor Protocol Number: EFC16295 Start Date*: Information not available in EudraCT
    Sponsor Name:Bioverativ Therapeutics Inc.
    Full Title: A Phase 3 open-label, multicenter study of the safety, efficacy, and pharmacokinetics of intravenous recombinant coagulation Factor VIII Fc-von Willebrand Factor-XTEN fusion protein (rFVIIIFc-VWF-X...
    Medical condition: Hemophilia A
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004850 10060612 Hemophilia A LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male
    Trial protocol: DE (Completed) FR (Completed) IE (Completed) GB (GB - no longer in EU/EEA) BE (Completed) SE (Completed) HU (Completed) NL (Completed) IT (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2007-001979-10 Sponsor Protocol Number: ALMED-07-C3-007 Start Date*: 2008-05-05
    Sponsor Name:AIR LIQUIDE
    Full Title: AN INTERNATIONAL PHASE III RANDOMISED TRIAL COMPARING THE PROPOFOL CONSUMPTION DURING GENERAL ANAESTHESIA WITH XENON IN INSPIRATORY CONCENTRATIONS OF 50 % AND 70% AND TOTAL IV ANAESTHESIA ALONE I...
    Medical condition: general anaesthesia.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) DE (Completed) GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-000265-20 Sponsor Protocol Number: LM02 Start Date*: 2012-06-06
    Sponsor Name:ABCSG (Austrian Breast & Colorectal Cancer Study Group)
    Full Title: A perioperative, single-arm multicenter Phase II academic trial to investigate the efficacy and safety of panitumumab in combination with irinotecan/5-fluorouracil/leucovorin (FOLFIRI) in patients ...
    Medical condition: previously untreated, wild-type RAS, potentially resectable colorectal cancer liver metastases
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
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