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Clinical trials for Prophylaxis

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    1,262 result(s) found for: Prophylaxis. Displaying page 1 of 64.
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    EudraCT Number: 2013-004653-25 Sponsor Protocol Number: Repha_1362 Start Date*: 2014-05-02
    Sponsor Name:Repha GmbH
    Full Title: Clinical trial for examination of efficacy and safety of ANGOCIN® Anti-Infekt N versus placebo in the continous prophylaxis of chronically recurring uncomplicated cystitis
    Medical condition: Continuous prophylaxis of chronically recurring uncomplicated cystitis
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004862 10011786 Cystitis chronic LLT
    21.1 10038359 - Renal and urinary disorders 10063057 Cystitis noninfective PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-005614-30 Sponsor Protocol Number: SOAP2016 Start Date*: 2016-07-07
    Sponsor Name:Uzsoki Utcai Kórház
    Full Title: SOAP Antibiotic prophylaxis trial Systemic versus combined systemic and Oral Antibiotic Prophylaxis in elective colorectal surgery
    Medical condition: In colorectal surgery wildely used bowel prep and systemic antibiotic prophylaxis. New data suggest that infective complications can be lowered if beside this regimen oral antibiotic profilaxis is ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2011-004070-29 Sponsor Protocol Number: E2011OBPROCHIR Start Date*: 2011-10-04
    Sponsor Name:Hopital Erasme
    Full Title: What are the optimal doses of cephalosporins of first and second generation to manage obese patients?
    Medical condition: Antibiotic prophylaxis in digestive surgery or any other surgery with antibiotic prophylaxis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10036898 Prophylaxis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2020-001048-24 Sponsor Protocol Number: NN7769-4514 Start Date*: 2021-05-18
    Sponsor Name:Novo Nordisk A/S
    Full Title: A multinational, open-label, randomised, controlled trial to investigate efficacy and safety of NNC0365-3769 (Mim8) in adults and adolescents with haemophilia A with or without inhibitors.
    Medical condition: Haemophilia A Haemophilia A with inhibitors
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10018938 Haemophilia A (Factor VIII) LLT
    20.0 10010331 - Congenital, familial and genetic disorders 10053751 Hemophilia A with anti factor VIII LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed) SK (Completed) DK (Completed) DE (Completed) BE (Completed) AT (Completed) LV (Completed) LT (Completed) FR (Completed) NL (Completed) PL (Completed) PT (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-005090-20 Sponsor Protocol Number: FADOI.01.2016 Start Date*: 2018-05-17
    Sponsor Name:FONDAZIONE FADOI
    Full Title: Rivaroxaban or placebo for extended antithrombotic prophylaxis after laparoscopic surgery for colorectal cancer: a randomized, double blind, placebo-controlled study. THE PRO-LAPS STUDY II
    Medical condition: Prevention of venous thromboembolism after laparoscopic surgery for colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10067650 Pulmonary embolism prophylaxis LLT
    21.1 100000004865 10012108 Deep venous thrombosis prophylaxis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2004-000365-35 Sponsor Protocol Number: A1501038 Start Date*: 2004-10-26
    Sponsor Name:Pfizer S.A
    Full Title: Prospective, Open-label, Non-comparative, Multicenter Study for the Secondary Prophylaxis of Invasive Fungal Infections (IFI) with Voriconazole in Patients with Allogeneic Stem Cell Transplants
    Medical condition: Secondary Prophylaxis of Invasive Fungal Infections
    Disease: Version SOC Term Classification Code Term Level
    7.0 10049085 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-004495-21 Sponsor Protocol Number: GS-MC-131-0165 Start Date*: 2006-09-07
    Sponsor Name:Gilead Sciences GmbH
    Full Title: Pilot study on safety of four weekly administrations of 7 mg/kg of liposomal amphotericin B (AmBisome®) in antifungal primary prophylaxis treatment of elderly patients with acute lymphoblastic leuk...
    Medical condition: Antifungal prophylaxis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10049085 Antifungal prophylaxis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-004891-36 Sponsor Protocol Number: NN7415-4307 Start Date*: 2019-11-20
    Sponsor Name:Novo Nordisk A/S
    Full Title: Efficacy and Safety of Concizumab prophylaxis in patients with haemophilia A or B without inhibitors
    Medical condition: Haemophilia A Haemophilia B
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10018938 Haemophilia A (Factor VIII) LLT
    20.0 10010331 - Congenital, familial and genetic disorders 10018939 Haemophilia B (Factor IX) LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male
    Trial protocol: DK (Trial now transitioned) SE (Trial now transitioned) ES (Ongoing) PL (Trial now transitioned) SK (Prematurely Ended) DE (Trial now transitioned) BG (Completed) GB (GB - no longer in EU/EEA) FR (Trial now transitioned) PT (Trial now transitioned) HR (Completed) HU (Trial now transitioned) LT (Trial now transitioned) EE (Trial now transitioned) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2007-004943-31 Sponsor Protocol Number: 21 March, 2007 Start Date*: 2007-10-03
    Sponsor Name:Centre of Thrombosis and Haemostasis
    Full Title: The VWD International Prophylaxis (VIP) Study
    Medical condition: Severe form of von Willebrand disease
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-000103-16 Sponsor Protocol Number: RC13_0008 Start Date*: 2013-06-21
    Sponsor Name:CHU de Nantes
    Full Title: Antifungal prophylaxis with Micafungin after cord blood allogeneic stem cell transplantation.
    Medical condition: Adult patients receiving allo-Stem Cell Transplantation using Cord Blood as source of stem cells
    Disease: Version SOC Term Classification Code Term Level
    18.0 10042613 - Surgical and medical procedures 10010980 Cord blood transplant therapy PT
    18.0 10042613 - Surgical and medical procedures 10049085 Antifungal prophylaxis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-002912-15 Sponsor Protocol Number: CHUBX2016/40 Start Date*: 2017-10-03
    Sponsor Name:CHU de Bordeaux
    Full Title: Secondary Prophylaxis after CMV disease in Kidney transplant patients targeted by γδ T cells immunomonitoring.
    Medical condition: Kidney transplants patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-001514-18 Sponsor Protocol Number: Cypher-TX_Pilot Start Date*: 2022-09-12
    Sponsor Name:University Medical Center Ljubljana
    Full Title: Cytomegalovirus Prophylaxis with Letermovir in Heart Transplant Recipients: A Non-randomized Cohort Pilot Study
    Medical condition: The focus of investigation in the proposed study protocol is the rates of Cytomegalovirus viremia and/or disease in patients after heart transplantation undergoing novel CMV prophylaxis protocol us...
    Disease:
    Population Age: Gender: Male, Female
    Trial protocol: SI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2010-022034-88 Sponsor Protocol Number: 20101111 Start Date*: 2010-09-20
    Sponsor Name:Odense University Hospital
    Full Title: Evaluation of the optimal dose of prophylactic anticoagulation with low- molecular- weight heparin administered subcutaneously to critically ill patients – part 2
    Medical condition: venous thromboembolism
    Disease: Version SOC Term Classification Code Term Level
    12.1 10049909 Venous thromboembolism prophylaxis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2006-002864-24 Sponsor Protocol Number: UMCN-AKF 06.02 Start Date*: 2006-09-25
    Sponsor Name:Dept. of Clinical Pharmacy, Radboud UMC Nijmegen, The Netherlands
    Full Title: Drug interactions between ATOvaquone used in MAlaria prophylaxis and antiretroviral agents in HIV-1 infected patients (ATOMA)
    Medical condition: malaria prophylaxis in HIV patients
    Disease: Version SOC Term Classification Code Term Level
    8.1 10025494 Malaria prophylaxis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2006-000612-24 Sponsor Protocol Number: WN06AN002 Start Date*: 2006-03-28
    Sponsor Name:Greater Glasgow Health Board (North Glasgow University Hospitals Division)
    Full Title: Trial of Aciclovir Prophylaxis of Herpes Infections in Critical Care
    Medical condition: Herpes simplex virus infection - prophylaxis in critically ill patients on ventilators
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-003916-19 Sponsor Protocol Number: 001 Start Date*: 2015-12-30
    Sponsor Name:Karl Landsteiner Institut für klinische Neurologie und Neuropsycholigie
    Full Title: Perioperative Levetiracetam for seizure prophylaxis in brain tumor patients. Prospective evaluation of side effects and efficacy
    Medical condition: Data on perioperative seizure prophylaxis in brain tumor patients as weil as on specific side effects is limited in scientific literature. Epileptic seizures during and after brain tumor surgery ma...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-001288-18 Sponsor Protocol Number: 16-API-01 Start Date*: 2019-01-08
    Sponsor Name:CHU de Nice
    Full Title: ASIC channels and migraine disorders - Proof of concept study on the efficacy of Amiloride in prophylaxis of Migraine with Aura - APAM study
    Medical condition: Migraine with aura
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10027607 Migraine with aura PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2009-014527-23 Sponsor Protocol Number: MG-ECALTA1 Start Date*: 2009-10-13
    Sponsor Name:KH der Elisabethinen Linz GmbH, I. Interne Abteilung
    Full Title: Anidulafungin in patients with hematologic malignancies - An open-label, prospective study to evaluate the safety profile at prophylactic and therapeutic dosages
    Medical condition: hematologic malignancies with risk for or active invasive fungal infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-004375-40 Sponsor Protocol Number: NGAM-12 Start Date*: 2020-07-09
    Sponsor Name:Octapharma Pharmazeutika Produktionsges.m.b.H.
    Full Title: Double-blind, Randomized, Placebo-controlled, Prospective Phase III Study Evaluating Efficacy and Safety of Panzyga in Primary Infection Prophylaxis in Patients with Chronic Lymphocytic Leukemia (“...
    Medical condition: Primary infection prophylaxis in patients with chronic lymphocytic leukemia (CLL) and secondary hypogammaglobulinemia
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004864 10008976 Chronic lymphocytic leukemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) HU (Trial now transitioned) DK (Trial now transitioned) IT (Trial now transitioned) GR (Trial now transitioned) ES (Ongoing) CZ (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-001556-35 Sponsor Protocol Number: GENA-21 Start Date*: 2013-07-26
    Sponsor Name:Octapharma AG
    Full Title: Prospective, open-label, multicentre phase 3b study to assess the efficacy and safety of individually tailored prophylaxis with Human-cl rhFVIII in previously treated adult patients with severe hae...
    Medical condition: Severe haemophilia A
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004850 10018938 Haemophilia A (Factor VIII) LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (Completed) SK (Completed) CZ (Completed) HU (Completed) BG (Completed) AT (Completed) ES (Prematurely Ended) DE (Completed) PL (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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