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Clinical trials for Response variable

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44351   clinical trials with a EudraCT protocol, of which   7378   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    716 result(s) found for: Response variable. Displaying page 1 of 36.
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    EudraCT Number: 2020-001391-15 Sponsor Protocol Number: V323Oct2020 Start Date*: 2020-04-24
    Sponsor Name:Royal College of Surgeons Ireland
    Full Title: A randomized double-blind placebo-controlled, pilot trial of intravenous plasma-purified alpha-1 antitrypsin for severe COVID-19 illness.
    Medical condition: acute respiratory distress sydnrome (ARDS) secondary to Covid-19
    Disease: Version SOC Term Classification Code Term Level
    23.0 10021881 - Infections and infestations 10051905 Coronavirus infection PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: View results
    EudraCT Number: 2004-004066-32 Sponsor Protocol Number: OB/ERYTH 2004-004066-32 Start Date*: 2006-02-01
    Sponsor Name:Silvia Delgado Aros
    Full Title: Reducción de la Ingesta Calórica en la Obesidad Mediante Modulación Farmacológica del Vaciamiento Gástrico Reduction of Caloric Intake in Obesity through Pharmacological Modulation of Gastric Empt...
    Medical condition: Obesidad/Sobrepeso Obesity/Overweight
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2008-008475-34 Sponsor Protocol Number: Remi-Sunburn-1 Start Date*: 2009-02-25
    Sponsor Name:Abteilung für Anaesthesie und Intensivmedizin, Medizinische Universität Wien
    Full Title: The effect of remifentanil on the reversal of established sunburn-induced hyperalgesia in human volunteers.
    Medical condition: This is a volunteer study in healthy volunteers. Pain research, reversal of hyperalgesia by IMP is studied
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2009-011599-31 Sponsor Protocol Number: RemiAnes1 Start Date*: 2009-06-26
    Sponsor Name:Abteilung für Anaesthesie und Intensivmedizin, Medizinische Universität Wien
    Full Title: The effect of high-dose remifentanil on the reversal of established capsaicin-induced hyperalgesia in human volunteers
    Medical condition: This is a volunteer study in healthy volunteers. Pain research, reversal of hyperalgesia by IMP ist studied
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2019-002593-31 Sponsor Protocol Number: 69HCL19_0003 Start Date*: 2019-11-05
    Sponsor Name:Hospices Civils de Lyon
    Full Title: Efficacy of Nintedanib per os as a treatment for epistaxis in HHT disease A national, randomized, multicenter phase II study EPICURE
    Medical condition: Hereditary Hemorrhagic Telangiectasia
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004850 10019887 Hereditary hemorrhagic telangiectasia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2005-000211-99 Sponsor Protocol Number: D1449L00010 Start Date*: 2005-04-12
    Sponsor Name:AstraZeneca A/S
    Full Title: Acutely Manic Patients Insufficiently Responding After 2 Weeks Continued Quetiapine Monotherapy: Continued Quetiapine Versus Sodium Valproate Add-on.
    Medical condition: Bipolar affective disorder
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2005-004056-13 Sponsor Protocol Number: HN015/HBVEXT001 Start Date*: 2007-01-24
    Sponsor Name:Henogen
    Full Title: A phase III, multicentric, multinational, long-term follow-up study to evaluate the persistence of anti-HBs antibodies at Months 12, 24 and 36 in pre-dialysis / peritoneal dialysis or haemodialysis...
    Medical condition: hepatitis B pre-dialysis, peritoneal dialysis and haemodialysis patient from 15 year of age
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-001855-11 Sponsor Protocol Number: CAIN457AGB01 Start Date*: 2013-09-06
    Sponsor Name:Novartis Pharmaceuticals UK Limited
    Full Title: Secukinumab In patients with moderate to severe active, chronic plaque psoriasis who have failed on TNFα antaGoNists: A clinical Trial EvalUating Treatment REsults
    Medical condition: Moderate to severe active, chronic plaque psoriasis
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004858 10071117 Plaque psoriasis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) IE (Completed)
    Trial results: View results
    EudraCT Number: 2020-001707-16 Sponsor Protocol Number: TOCICOVID Start Date*: 2020-06-25
    Sponsor Name:IIS BIODONOSTIA
    Full Title: PHASE III RANDOMIZED, UNICENTRIC, OPEN, CONTROLLED CLINICAL TRIAL TO DEMONSTRATE THE EFFECTIVENESS OF TOCILIZUMAB AGAINST SYSTEMIC CORTICOTHERAPY IN PATIENTS ENTERED BY COVID-19 WITH BILATERAL PNEU...
    Medical condition: bilateral SARS-CoV-2 pneumonia with poor clinical course
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-000937-54 Sponsor Protocol Number: MC2-03-C1 Start Date*: 2015-08-03
    Sponsor Name:DRUG DELIVERY SOLUTIONS ApS (PART OF MC2 BIOTEK GROUP)
    Full Title: A phase II, multicenter, randomized, double-masked, 4 parallel arms, controlled 6-month trial designed to evaluate the safety and efficacy of PAD ciclosporin (CsA 0.06% and 0.03%) ophthalmic disper...
    Medical condition: ocular dryness (Dry Eye Disease - DED)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000014904 10013778 Dry eyes LLT
    20.0 100000014904 10013777 Dry eye syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DK (Completed) NO (Completed) AT (Completed) ES (Completed) PT (Completed) FR (Completed) SK (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2005-001593-26 Sponsor Protocol Number: H 1005 6002 - 05/07 Start Date*: 2005-07-27
    Sponsor Name:HERMAL Kurt Herrmann GmbH & Co OHG
    Full Title: Topical treatment of verrucae vulgares with Verrumal® in organtransplant recipients (OTR) – prospective, double-blind, placebo-controlled randomised trial
    Medical condition: Verrucae vulgares or common warts are benign epithelial tumors of the skin caused by infection with human papilloma viruses (HPV). Due to immunosuppression organ transplant recipients are at high r...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-021188-34 Sponsor Protocol Number: LT2380-PIII-05/10 Start Date*: 2011-07-01
    Sponsor Name:Laboratoires Théa
    Full Title: Efficacy and safety assessment of intracameral T2380 (Fixed combination of lidocaine, phenylephrine and tropicamide) for mydriasis and anaesthesia in phacoemulsification cataract surgery
    Medical condition: The aim of this clinical study will be to develop a combination of active substances enabling to obtain at the same time a mydriasis and an anaesthesia during cataract surgery
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10011719 Cycloplegia PT
    14.1 10042613 - Surgical and medical procedures 10002325 Anesthesia local LLT
    14.1 10015919 - Eye disorders 10028521 Mydriasis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PT (Completed) DE (Completed) BE (Completed) AT (Completed) ES (Ongoing) SE (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-004340-11 Sponsor Protocol Number: 17403 Start Date*: 2018-06-13
    Sponsor Name:Bayer AG
    Full Title: A randomized, open label, multicenter Phase 2/3 study to evaluate the efficacy and safety of rogaratinib (BAY 1163877) compared to chemotherapy in patients with FGFR-positive locally advanced or me...
    Medical condition: mRNA FGF receptor 1 and 3 positive locally advanced or metastatic urothelial carcinoma progressed after prior platinum-containing chemotherapy
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10064467 Urothelial carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) IE (Completed) NL (Prematurely Ended) FR (Completed) AT (Completed) CZ (Completed) ES (Completed) PT (Completed) FI (Completed) SK (Completed) HU (Completed) DK (Completed) BE (Completed) SE (Completed) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-004053-10 Sponsor Protocol Number: HN014/HBV-001 Start Date*: 2006-02-02
    Sponsor Name:Henogen
    Full Title: A phase III, multicentric, multinational, controlled, randomised, open study comparing the immunogenicity, reactogenicity and safety of Henogen’s new adjuvanted hepatitis B vaccine, HB-AS02V, admin...
    Medical condition: hepatitis B naïve pre-dialysis, peritoneal dialysis and haemodialysis patients from 15 years of age
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) CZ (Completed) BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-001814-85 Sponsor Protocol Number: PNT2258-04-Richter's Start Date*: 2016-03-10
    Sponsor Name:ProNAi Therapeutics, Inc.
    Full Title: A Phase II Study of PNT2258 in Patients With Richter's Transformation (RT)
    Medical condition: Diffuse large B-cell non-Hodgkin's lymphoma with Richter's Transformation (RT) from chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)
    Disease: Version SOC Term Classification Code Term Level
    18.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10058728 Richter's syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) BE (Prematurely Ended) HU (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-003826-10 Sponsor Protocol Number: EAGLE Start Date*: 2014-01-24
    Sponsor Name:IRCCS- Mario Negri Institute
    Full Title: EVALUATING THE MORPHOFUNCTIONAL EFFECTS OF ECULIZUMAB THERAPY IN PRIMARY MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS: A PILOT, SINGLE ARM STUDY IN TEN PATIENTS WITH PERSISTENT HEAVY PROTEINURIA
    Medical condition: Membranoproliferative glomerulonephritis
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2022-003913-12 Sponsor Protocol Number: 22/589-EC_M. Start Date*: 2023-03-07
    Sponsor Name:COMPLUTENSE UNIVERSITY OF MADRID
    Full Title: Diode laser and photodynamic therapy Versus Ciclopirox Hydroxypropyl Chitosan. Randomised controlled clinical trial.
    Medical condition: Onychomycosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-005223-18 Sponsor Protocol Number: NRA6280030 Start Date*: 2005-05-12
    Sponsor Name:Childrens´ Hospital Erlangen
    Full Title: Evaluation of growth response in short children suffering from a disease with growth retardation and treated with Somatropin: A prospective, longitudinal non-randomised, open, phase II study
    Medical condition: Genotropin®) is approved for treatment of short statured children in specific indications. A benefit can also be achieved in other pathological conditions that lead to growth retardation. Because ...
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-001886-26 Sponsor Protocol Number: TRI-002-INT Start Date*: 2010-06-29
    Sponsor Name:GALENICA S.A.
    Full Title: A multicenter, double-blind, randomized, placebo controlled phase III study of the efficacy and safety of Trimebutine 300 mg twice daily for the relief of functional dyspeptic patients
    Medical condition:
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-002991-15 Sponsor Protocol Number: SOLTI-1804 Start Date*: 2019-11-04
    Sponsor Name:SOLTI
    Full Title: HER2-PREDICT: Estudio Traslacional De Muestras De Tumor Procedentes De Los Ensayos Ds8201-A-U301 y Ds8201-A-U302
    Medical condition: Her2‑positive, unresectable and/or metastatic breast cancer.
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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