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Clinical trials for Varices

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
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    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    88 result(s) found for: Varices. Displaying page 1 of 5.
    1  2  3  4  5  Next»
    EudraCT Number: 2009-016500-24 Sponsor Protocol Number: BLEPS Start Date*: 2010-05-11
    Sponsor Name:Fundació Clinic per a la Recerca Biomèdica
    Full Title: Estudio multicéntrico, aleatorizado, doble-ciego, controlado con placebo, sobre la eficacia de la asociación de simvastatina al tratamiento estándar en la prevención de la recidiva hemorrágica en p...
    Medical condition: Prevención de la recidiva hemorrágica en pacientes con cirrosis y hemorragia por varices esofágicas.
    Disease: Version SOC Term Classification Code Term Level
    9 10005112 Bleeding esophageal varices LLT
    9 10036200 Portal hypertension LLT
    9 10019669 Hepatic fibrosis and cirrhosis HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2010-021615-17 Sponsor Protocol Number: 26141788A Start Date*: 2010-08-31
    Sponsor Name:Lars H. Rasmussen
    Full Title: Randomized trial comparing endovascular laser, foam sclerotherapy and stripping in patients with varicose veins due to incompetent small saphenous vein
    Medical condition: Varicose veins
    Disease: Version SOC Term Classification Code Term Level
    12.1 10047001 Varicose veins LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-002237-37 Sponsor Protocol Number: CONHEMO-2006 Start Date*: 2008-11-02
    Sponsor Name:Institut de Recerca del Hopsital de la Santa Creu i Sant Pau
    Full Title: TRATAMIENTO GUIADO SEGÚN RESPUESTA HEMODINÁMICA, PARA LA PREVENCIÓN DE RECIDIVA HEMORRÁGICA POR VARICES ESOFÁGICAS. ESTUDIO CONTROLADO Y ALEATORIZADO, FASE IV.
    Medical condition: Pacientes de ambos sexos, con cirrosis hepática, con edad superior a 18 años, que hayan presentado un episodio de hemorragia por varices esofágicas.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10009211 Cirrhosis liver LLT
    9.1 10055489 Esophageal varices in cirrhosis of liver LLT
    Population Age: Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-001983-31 Sponsor Protocol Number: GT-031 Start Date*: 2021-05-04
    Sponsor Name:Galectin Therapeutics Inc.
    Full Title: A Seamless, Adaptive, Phase 2b/3, Double-Blind, Randomized, Placebo-controlled, Multicenter, International Study Evaluating the Efficacy and Safety of Belapectin (GR MD-02) for the Prevention of Es...
    Medical condition: Esophageal Varices in NASH Cirrhosis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004871 10009214 Cirrhosis of liver without mention of alcohol LLT
    21.1 100000004856 10055489 Esophageal varices in cirrhosis of liver LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned) GB (GB - no longer in EU/EEA) DE (Trial now transitioned) BE (Trial now transitioned) PL (Trial now transitioned) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-004565-33 Sponsor Protocol Number: EASI Start Date*: 2006-11-16
    Sponsor Name:Chemische Fabrik Kreussler & Co.GmbH
    Full Title: Efficacy and safety of Aethoxysklerol compared to Sodium Tetradecyl Sulfate and Isotonic Saline (placebo) for the treatment of reticular veins and spider veins including subgroup to investigate the...
    Medical condition: Patients suffering from varicose veins (spider veins or reticular veins in the legs) should be treated with a sclerosing agent.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10047001 Varicose veins LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-005147-10 Sponsor Protocol Number: KORPO - 0104 Start Date*: 2005-01-31
    Sponsor Name:KORPO S.R.L.
    Full Title: Randomised controlled clinical trial to evaluate the efficacy of a sodium salicylate hydroglyceric solution used at different concentrations in the aesthetic and functional sclerotherapy of veins, ...
    Medical condition: Patients with ecstatic vessels in inferior limbs
    Disease: Version SOC Term Classification Code Term Level
    6.1 10057165 HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2018-002509-78 Sponsor Protocol Number: BOPPP Start Date*: 2019-04-24
    Sponsor Name:Kings College Hospital NHS Foundation Trust
    Full Title: Beta-blockers Or Placebo for Primary Prophylaxis of oesophageal varices (BOPPP Trial). A blinded, UK multi-centre, clinical effectiveness and cost-effectiveness randomised controlled trial.
    Medical condition: Liver cirrhosis with small oesophageal varices
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004871 10024667 Liver cirrhosis LLT
    21.1 100000004856 10055489 Esophageal varices in cirrhosis of liver LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2014-000102-35 Sponsor Protocol Number: 35128 Start Date*: 2014-12-19
    Sponsor Name:Clinica Medica 5
    Full Title: Effect of administration "add on" of Rifaximin on portal hypertension of patients with liver cirrhosis and esophageal varices in standard therapy with propranolol
    Medical condition: Portal hypertension, liver cirrhosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-022516-39 Sponsor Protocol Number: SIMBETA Start Date*: 2011-10-27
    Sponsor Name:Institut de Recerca HSCSP
    Full Title: Estudio aleatorizado sobre el efecto hemodinámico de la asociación de simvastatina con betabloqueantes no cardioselectivos en pacientes con cirrosis hepática e hipertensión portal clínicamente ...
    Medical condition: Se trata de un estudio hemodinámico, para el estudio del efecto en la progresión de hipertensión portal, de la asociación de simvastatina al tratamiento convencional de la profilaxis primaria en pa...
    Disease: Version SOC Term Classification Code Term Level
    13 10019654 Trastornos hepáticos y hepatobiliares HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2012-003132-23 Sponsor Protocol Number: 41354 Start Date*: 2012-11-27
    Sponsor Name:
    Full Title: Local tumescent anaesthesia with ambulatory phlebectomy according to Muller
    Medical condition: Varices according to the CEAP classification
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-006208-11 Sponsor Protocol Number: 1544?H?254 Start Date*: 2012-04-18
    Sponsor Name:CAIBER
    Full Title: A randomized, controlled multicenter clinical trial comparing endoscopic band ligation versus oral carvedilol in the primary prophylaxis of esophageal variceal bleeding in patients with cirrosis
    Medical condition: Esophageal variceal bleeding in patients with cirrhosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-014721-16 Sponsor Protocol Number: IRRB/19/09 Start Date*: 2009-11-18
    Sponsor Name:ISTITUTO MEDITERRANEO PER I TRAPIANTI E TERAPIE AD ALTA SPECIALIZZAZIONE
    Full Title: Controlled randomized pilot study for characterization and identification of CD34+ stem cells in the splancnic distrect after GCSF stimolation in cirrhotic patients
    Medical condition: Liver cirrhosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-005482-10 Sponsor Protocol Number: RN1001-0042 Start Date*: 2006-03-13
    Sponsor Name:Renovo
    Full Title: A double blind, placebo controlled, randomised dose response trial to investigate the efficacy of Juvista in the improvement of scar appearance when applied to approximated wound margins following ...
    Medical condition: Patients undergoing varicose vein removal with ligation and stripping.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) LT (Completed) LV (Completed) BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-002567-42 Sponsor Protocol Number: 5A Start Date*: 2015-07-15
    Sponsor Name:Stockholm County Council, Karolinska University Hospital Huddinge, Dept of Anesthesiology and Intensive Care
    Full Title: Predictors of albumin synthesis rate in severe liver failure. An open exploratory study in patients with chronic liver failure assessed for liver transplantation
    Medical condition: Severe chronic liver failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-001472-18 Sponsor Protocol Number: UDT-2/PHT Start Date*: 2011-05-10
    Sponsor Name:STZ 1172 Gesundheitsförderung und Stoffwechselforschung
    Full Title: Double-Blind, Randomised, Cross-Over, Placebo-Controlled, Single-Centre Phase IIa Clinical Study on the Influence of Udenafil on the Portal Flow in Cirrhotic Patients with Portal Hypertension
    Medical condition: Portal hypertension, liver cirrhosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-001069-26 Sponsor Protocol Number: 06/45/02 Start Date*: 2009-04-06
    Sponsor Name:University of Aberdeen
    Full Title: Randomised controlled trial comparing foam sclerotherapy, alone or in combination with endovenous laser therapy, with conventional surgery as a treatment for varicose veins
    Medical condition: Varicose Veins
    Disease: Version SOC Term Classification Code Term Level
    9.1 10047013 Varicose veins of lower extremities LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2021-005171-40 Sponsor Protocol Number: 1366-0029 Start Date*: 2022-06-20
    Sponsor Name:Boehringer Ingelheim SComm
    Full Title: Randomised, open-label and parallel group trial to investigate the effects of oral BI 685509 alone or in combination with empagliflozin on portal hypertension after 8 weeks treatment in patients wi...
    Medical condition: portal hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.1 10019805 - Hepatobiliary disorders 10036200 Portal hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Trial now transitioned) DK (Trial now transitioned) NL (Ongoing) IT (Trial now transitioned) FR (Trial now transitioned) DE (Ongoing) AT (Trial now transitioned) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-000984-29 Sponsor Protocol Number: AGO/2011/003 Start Date*: 2011-04-07
    Sponsor Name:Ghent University Hospital
    Full Title: Prospectieve vergelijkende studie tussen verschillende tumescentie technieken bij endoveneuze ablatie behandeling voor varices
    Medical condition: Patiënten die behandeld worden voor endoveneuze ablatio van een oppervlakkig veneuze insufficiëntie
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2004-000443-17 Sponsor Protocol Number: NV-02B-011 Start Date*: 2004-09-26
    Sponsor Name:Idenix Pharmaceuticals, Inc.
    Full Title: A Randomized, Double-Blind Trial of Telbivudine (LdT) versus Lamivudine in Adults with Decompensated Chronic Hepatitis B and Evidence of Cirrhosis
    Medical condition: Decompensated Chronic Hepatitis B and Evidence of Cirrhosis
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) LV (Completed)
    Trial results: View results
    EudraCT Number: 2005-003557-27 Sponsor Protocol Number: SA-388-4-1 Start Date*: Information not available in EudraCT
    Sponsor Name:Dean of the Medical Faculty (University of Bonn)
    Full Title: Covered Transjugular Intrahepatic Portosystemic Stent Shunt versus Optimized medical Treatment for the Secondary Prevention of Variceal Bleeding in Cirrhosis
    Medical condition: liver cirrhosis; esophageal (variceal) bleeding
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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