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Clinical trials for Glaucoma, Open-Angle

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44351   clinical trials with a EudraCT protocol, of which   7378   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    147 result(s) found for: Glaucoma, Open-Angle. Displaying page 3 of 8.
    « Previous 1  2  3  4  5  6  7  8  Next»
    EudraCT Number: 2014-003037-26 Sponsor Protocol Number: 192024-091 Start Date*: 2015-03-16
    Sponsor Name:Allergan Limited
    Full Title: The Efficacy and Safety of Bimatoprost SR in Patients With Open-angle Glaucoma or Ocular Hypertension
    Medical condition: Open-angle Glaucoma and Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    20.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    20.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) AT (Completed) BE (Completed) ES (Completed) DK (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2018-003597-26 Sponsor Protocol Number: 1698-302-007 Start Date*: 2019-11-07
    Sponsor Name:Allergan Ltd.
    Full Title: An Extension Trial to Evaluate the Long-term Safety and Efficacy of Bimatoprost SR in Patients with Open Angle Glaucoma or Ocular Hypertension
    Medical condition: Open-angle Glaucoma and Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    20.0 10015919 - Eye disorders 10030856 Open-angle glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) DK (Completed) AT (Prematurely Ended) DE (Ongoing) BE (Completed) ES (Ongoing) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-003631-34 Sponsor Protocol Number: 192024-095 Start Date*: 2017-01-12
    Sponsor Name:Allergan Limited
    Full Title: A Comparison of Bimatoprost SR to Selective Laser Trabeculoplasty in Patients with Open-Angle Glaucoma or Ocular Hypertension
    Medical condition: Open-angle glaucoma (OAG) or Ocular hypertension (OHT)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    20.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    20.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) ES (Temporarily Halted) CZ (Completed) FR (Completed) DK (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2020-004307-14 Sponsor Protocol Number: BECRO/ACT/LATANOS Start Date*: 2021-02-12
    Sponsor Name:actrevo GmbH
    Full Title: Non-inferiority, Randomized, Observer-blind, two Parallel Group, Clinical Trial for Comparing the Efficacy and Tolerability of a new Generic BAC-free Formulation of Latanoprost 0.05 mg/mL eye drops...
    Medical condition: Open angle glaucoma or ocular hypertension Elevated IOP and paediatric glaucoma.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    20.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: View results
    EudraCT Number: 2007-004023-38 Sponsor Protocol Number: GLC0107 Start Date*: 2007-07-30
    Sponsor Name:IRCCS- FONDAZIONE G.B. BIETTI PER LO STUDIO E LA RICERCA IN OFTALMOLOGIA-ONLUS
    Full Title: Prospective, multicentric, double-masked clinical study to compare the efficacy and safety of Ganfort and Duotrav in primary open angle and pseudoexfoliative glaucoma patients previously treated wi...
    Medical condition: Glaucoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10018304 Glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) AT (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-003816-21 Sponsor Protocol Number: RDG-10298 Start Date*: 2012-01-11
    Sponsor Name:S.A. Alcon-Couvreur N.V
    Full Title: Multi-Center Study Assessing Efficacy and Tolerability of TRAVATAN® Solution without BAK, containing Polyquad® Preservative (0.004% travoprost) in Patients Previously on latanoprost 0.005% or bimat...
    Medical condition: Open angle Glaucoma Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    14.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) SE (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2009-015798-11 Sponsor Protocol Number: 2452-001 Start Date*: 2010-03-25
    Sponsor Name:Merck & Co., Inc.
    Full Title: “Ensayo de fase III, aleatorizado, controlado con un fármaco de comparación activo, con doble enmascaramiento, de doce semanas de duración, para comparar la eficacia y la seguridad de MK-2452 (0,00...
    Medical condition: Glaucoma de ángulo abierto e hipertensión ocular /Open-Angle Glaucoma and Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    9 10018307 Glaucoma and ocular hypertension HLGT
    9 10030348 Open angle glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2018-001727-39 Sponsor Protocol Number: POP03 Start Date*: 2018-10-16
    Sponsor Name:Polpharma S.A.
    Full Title: A PHASE III, MULTICENTRE, RANDOMISED, INVESTIGATOR-MASKED, CROSSOVER, COMPARATIVE, NON-INFERIORITY TRIAL EVALUATING THE EFFICACY AND TOLERABILITY OF GENERIC LATANOPROST 0.05 MG/ML EYE DROPS SOLUTIO...
    Medical condition: Ocular hypertension and open angle glaucoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    20.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2021-003387-27 Sponsor Protocol Number: 848300145/0129/1POP04 Start Date*: 2021-11-02
    Sponsor Name:Pharmaceutical Works Polpharma S.A. (Polpharma S. A.)
    Full Title: A PHASE III, MULTICENTRE, RANDOMISED, INVESTIGATOR-MASKED, CROSS-OVER, COMPARATIVE, NON-INFERIORITY TRIAL OF GENERIC LATANOPROST + TIMOLOL (50μG + 5MG)/ML EYE DROPS, SOLUTION (POLPHARMA S.A.) COMPA...
    Medical condition: Ocular hypertension and open angle glaucoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    20.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002750-38 Sponsor Protocol Number: C-08-09 Start Date*: 2008-10-22
    Sponsor Name:Alcon Research Ltd
    Full Title: 24-hour IOP control with Travoprost / Brinzolamide fixed combination once-daily (QD)in the evening vs TRAVATAN
    Medical condition: Open-angle glaucoma or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015919 Eye disorders SOC
    9.1 10030348 Open angle glaucoma LLT
    9.1 10030043 Ocular hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-000515-29 Sponsor Protocol Number: EMD-06-03 Start Date*: 2007-07-04
    Sponsor Name:Alcon Laboratories Inc.
    Full Title: Adherencia de los pacientes en el uso de Travalert® para la instilación de una combinación fija de travoprost 0.004% / timolol 0.5% comparado con un régimen concomitante de travoprost 0.004% y timo...
    Medical condition: Reducción de la presión intraocular en pacientes con glaucoma de angulo abierto o con hipertensión ocular, que no respondan a monoterapia de betabloqueantes o análogos de las prostaglandinas Intr...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030348 Open angle glaucoma LLT
    9.1 10030043 Ocular hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2014-003186-24 Sponsor Protocol Number: 192024-092 Start Date*: 2015-04-23
    Sponsor Name:Allergan Limited
    Full Title: The Efficacy and Safety of Bimatoprost SR in Patients With Open-angle Glaucoma or Ocular Hypertension
    Medical condition: Open-angle Glaucoma and Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    20.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    20.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) CZ (Completed) DE (Trial now transitioned) IT (Completed) NL (Completed) PT (Completed)
    Trial results: View results
    EudraCT Number: 2019-003089-42 Sponsor Protocol Number: OPHT-250719 Start Date*: 2019-12-23
    Sponsor Name:Medical University of Vienna, Department of Clinical Pharmacology
    Full Title: The effect of Tetrahydrocannabinol on ocular hemodynamics in patients with primary open angle glaucoma- A Phase II Study
    Medical condition: The study will be carried out in patients with primary open angle glaucoma and healthy subjects
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004853 10036719 Primary open angle glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002780-13 Sponsor Protocol Number: C-07-63 Start Date*: 2008-09-04
    Sponsor Name:Alcon Research, Ltd.
    Full Title: A Three-Month, Multicenter, Double-Masked Study Comparing the Safety and Efficacy of the Fixed Combination Travoprost + Brinzolamide Eye Drops, Suspension vs Travatan vs Azopt in Patients with Open...
    Medical condition: open-angle glaucoma or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030348 Open angle glaucoma LLT
    9.1 10030348 Open angle glaucoma PT
    9.1 10015919 Eye disorders SOC
    9.1 10030043 Ocular hypertension LLT
    9.1 10030043 Ocular hypertension PT
    9.1 10015919 Eye disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) DE (Prematurely Ended) ES (Completed) BE (Completed) HU (Prematurely Ended) GB (Prematurely Ended) IT (Prematurely Ended) PT (Prematurely Ended) AT (Prematurely Ended) LV (Completed) SE (Prematurely Ended) EE (Prematurely Ended) LT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-005091-42 Sponsor Protocol Number: 192024-041D Start Date*: 2012-05-08
    Sponsor Name:Allergan Limited
    Full Title: An Open Label (Stage 1) and Randomized (Stage 2), 24-Month Study of Safety and Efficacy of Bimatoprost Drug Delivery System in Patients With Open-Angle Glaucoma or Ocular Hypertension
    Medical condition: open-angle glaucoma (OAG) and ocular hypertension (OHT)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    14.1 10015919 - Eye disorders 10030043 Ocular hypertension PT
    14.1 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-000026-22 Sponsor Protocol Number: QTM/OMN0112 Start Date*: 2012-07-23
    Sponsor Name:Omnivision GmbH
    Full Title: Open, Observer-blind, two Parallel Group, Randomized, Multicentric Clinical Phase III Trial on the Comparison of Efficacy and Tolerability of a New Preservative-free Formulation of Travoprost 40 µg...
    Medical condition: Primary open angle glaucoma or intraocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10030043 Ocular hypertension PT
    14.1 10015919 - Eye disorders 10036719 Primary open angle glaucoma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-005339-15 Sponsor Protocol Number: QTM/OMN0211 Start Date*: 2012-02-03
    Sponsor Name:Omnivision GmbH
    Full Title: Open, Observer-blind, two Parallel Group, Randomized, Multicentric Clinical Phase III Trial on the Comparison of Efficacy and Tolerability of a New Preservative-free Formulation of the Fixed Combin...
    Medical condition: Primary open angle glaucoma or intraocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    14.0 10015919 - Eye disorders 10036719 Primary open angle glaucoma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2010-024512-34 Sponsor Protocol Number: C-10-040 Start Date*: 2011-05-17
    Sponsor Name:Alcon Research, Ltd.
    Full Title: Safety and IOP-Lowering Efficacy of Brinzolamide 10 mg/ml / Brimonidine 2 mg/ml Fixed Combination Eye Drops, Suspension compared to Brinzolamide 10 mg/ml Eye Drops, Suspension and Brimonidine 2 mg/...
    Medical condition: Open-angle glaucoma and ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004853 10030856 Open-angle glaucoma LLT
    14.1 100000004853 10020784 Hypertension ocular LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) PT (Completed) LV (Completed) DE (Completed) HU (Completed) LT (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-004872-37 Sponsor Protocol Number: 77552 Start Date*: 2007-11-21
    Sponsor Name:Santen Oy
    Full Title: A phase IIIb study on the changes in ocular signs, symptoms and conjunctival inflammatory markers in patients with ocular hypertension or primary open-angle glaucoma switched from preserved latanop...
    Medical condition: Ocular hypertension or open angle glaucoma patients are enrolled into this trial.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) SE (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-005607-18 Sponsor Protocol Number: OPHT-011007 Start Date*: 2009-04-02
    Sponsor Name:Ursapharm Arzneimittel GmbH & Co KG
    Full Title: An open study comparing the effects of moxaverine on ocular blood flow in patients with age- related macular degeneration, primary open angle glaucoma and healthy control subjects
    Medical condition: glaucoma age-related macular degeneration
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036719 Primary open angle glaucoma LLT
    9.1 10064930 Age-related macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
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