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Clinical trials for Left ventricle

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    148 result(s) found for: Left ventricle. Displaying page 4 of 8.
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    EudraCT Number: 2017-000222-35 Sponsor Protocol Number: 2017-000222-35 Start Date*: 2017-07-21
    Sponsor Name:Medical University of Vienna
    Full Title: Effect of etelcalcetide on cardiac hypertrophy in hemodialysis patients – a randomized controlled trial
    Medical condition: Secondary hyperparathyroidism in adult patients with chronic kidney disease on hemodialysis therapy.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-003146-17 Sponsor Protocol Number: QGC001-2QG4 Start Date*: 2019-07-12
    Sponsor Name:Quantum Genomics
    Full Title: A Phase 2, Double-blind, Active-controlled, Dose-titrating Efficacy and Safety Study of Firibastat (QGC001) Compared to Ramipril Administered Orally, Twice Daily, Over 12 Weeks to Prevent Left Vent...
    Medical condition: Prevention of left ventricular dysfunction after acute anterior myocardial infarction
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) SK (Completed) HU (Completed) ES (Ongoing) GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2014-001205-41 Sponsor Protocol Number: VIPER–AMI Start Date*: 2015-01-09
    Sponsor Name:Sociedade Portuguesa de Cardiologia
    Full Title: VIldagliptin as an ischemic PERconditioning mimetic agent in Acute Myocardial Infarction – A single centre, randomized, parallel-group, double-blind clinical trial, for assessing the effectiveness...
    Medical condition: ST Elevation Myocardial Infarction
    Disease: Version SOC Term Classification Code Term Level
    17.1 10007541 - Cardiac disorders 10000891 Acute myocardial infarction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-002742-42 Sponsor Protocol Number: 2013DM19 Start Date*: 2014-12-23
    Sponsor Name:University of Dundee/ NHS Tayside
    Full Title: Research into the Effect Of SGLT2 inhibition on left ventricular Remodelling in patients with heart failure and diabetes Mellitus
    Medical condition: Type 2 diabetes and Heart Failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-002847-28 Sponsor Protocol Number: CRLX030A2208 Start Date*: 2014-06-26
    Sponsor Name:Novartis Pharma Services AG
    Full Title: Multicenter, open-label, dose escalation study to evaluate safety, tolerability and pharmacokinetics of RLX030 in addition to standard of care in pediatric patients from birth to <18 years of age, ...
    Medical condition: acute heart failure
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004849 10000803 Acute heart failure LLT
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-003902-29 Sponsor Protocol Number: EASI-Child Start Date*: 2020-04-30
    Sponsor Name:IRCCS, OSPEDALE PEDIATRICO BAMBINO GESÙ DI ROMA
    Full Title: Early Administration of Ivabradine in Children with Heart Failure.
    Medical condition: Acute hearth failure in dilated cardiomyopathy.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10007541 Cardiac disorders SOC
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2014-003273-42 Sponsor Protocol Number: 14AOI11 Start Date*: 2014-12-23
    Sponsor Name:CHU de Nice
    Full Title: Comparing a diuretic vascular filling in the initial management of acute pulmonary embolism with right ventricular dysfunction normotensive
    Medical condition: acute pulmonary embolism with right ventricular dysfunction normotensive
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004855 10050071 Embolism lung LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-002520-33 Sponsor Protocol Number: SNT-II-1 Start Date*: 2005-09-06
    Sponsor Name:Santhera Pharmaceuticals LLC
    Full Title: A Phase IIa double blind, randomised, placebo controlled, single centre study at the university of Leuven to assess the efficacy and tolerability of idebenone in 10 - 16 year old males with cardiac...
    Medical condition: Duchenne Muscular Dystrophy
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2017-001037-72 Sponsor Protocol Number: ABR60023 Start Date*: 2017-12-01
    Sponsor Name:Leiden University Medical Center
    Full Title: The efficacy of flEcainide Compared To metOprolol in reducing Premature ventrIcular Complexes. An open label cross-over study in pediatric patients.
    Medical condition: frequent premature ventricular contractions
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-011485-28 Sponsor Protocol Number: MANAMI101-09 Start Date*: 2009-08-12
    Sponsor Name:PledPharma AB
    Full Title: A local feasibility study of mangafodipir as an adjunct to percutaneous coronary intervention in patients with acute myocardial infarction
    Medical condition: Patients with acute myocardial infarction decided for treatment by percutaneous coronary intervention (PCI) are included. The test drug mangafodipir is administered intravenously just prior to PCI....
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2011-005435-98 Sponsor Protocol Number: version_2.0_dated_19.04.2011 Start Date*: 2012-06-21
    Sponsor Name:Śląski Uniwersytet Medyczny w Katowicach
    Full Title: A randomized, prospective, double-blind study with placebo to evaluate the efficacy of treatment of patients with angina resistant to pharmacological treatment and induced myocardial ischemia with...
    Medical condition: Stable angina pectoris CCS II-IV
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10049194 Stable angina pectoris LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: View results
    EudraCT Number: 2013-003976-11 Sponsor Protocol Number: HSG-1-13 Start Date*: 2014-01-24
    Sponsor Name:Helsinki University Central Hospital
    Full Title: Effects of S-1 and capecitabine in combination with oxaliplatin on the coronary artery blood flow in patients metastatic gastrointestinal tract adenocarcinoma
    Medical condition: Metastatic gastrointestinal tract adenocarcinoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended) DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-007699-40 Sponsor Protocol Number: C3BS-C-07-1 Start Date*: 2009-02-25
    Sponsor Name:Cardio3 BioSciences
    Full Title: C-Cure - Safety, feasibility and efficacy of guided bone marrow-derived cardiopoietic mesenchymal stem cells for the treatment of heart failure secondary to ischemic cardiomyopathy
    Medical condition: C-Cure is indicated for the treatment of heart failure (NYHA class II and III with a Left Ventricular Ejection Fraction > 15 % and <= 40%) secondary to ischemic cardiomyopathy.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064081 Heart failure NYHA class III LLT
    9.1 10064080 Heart failure NYHA class II LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-006639-24 Sponsor Protocol Number: 2020/ABM/01/00080 Start Date*: 2022-10-19
    Sponsor Name:The Cardinal Stefan Wyszyński Institute of Cardiology
    Full Title: Multicenter Polish Study of the Use of Bromocriptine in Perinatal Cardiomyopathy. New BioMarkers in the Early Diagnosis of Peripartum CardioMyopathy. PolBrom-PPCM
    Medical condition: PeriPartum Cardiomiopathy
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: PL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-002587-24 Sponsor Protocol Number: CMD_ALISKIREN Start Date*: 2011-10-20
    Sponsor Name:FONDAZIONE CENTRO S. RAFFAELE DEL MONTE TABOR
    Full Title: Effects of Aliskiren on microcirculation dysfunction in patients affected by hypertension
    Medical condition: dysfunction of coronary microcirculation in arterial hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 10047065 - Vascular disorders 10010164 Hypertension complications HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2020-005302-26 Sponsor Protocol Number: DW.0701.005.2020P Start Date*: 2023-01-05
    Sponsor Name:John Paul II Hospital
    Full Title: The effect of sacubitril/valsartan versus ramipril on left ventricular function and remodeling in patients with ischemic heart failure with mid-range ejection fraction
    Medical condition: heart failure with moderately reduced ejection fraction (HFmrEF)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10010684 Congestive heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2007-002809-48 Sponsor Protocol Number: CRO782 Start Date*: 2013-04-17
    Sponsor Name:Imperial College London and Imperial College Healthcare NHS Trust
    Full Title: Investigation of the safety and feasibility of AAV1/SERCA2a gene transfer in patients with chronic heart failure and a left ventricular assist device
    Medical condition: Advanced heart failure
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004849 10010684 Congestive heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-000789-31 Sponsor Protocol Number: RGH201 Start Date*: 2018-02-09
    Sponsor Name:Kuopio University Hospital Heart Center
    Full Title: Clinical development and proof of principle testing of new regenerative VEGF-D therapy for cost-effective treatment of refractory angina. A phase II randomized, double-blinded, placebo-controlled s...
    Medical condition: Refractory angina
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10064262 Refractory angina pectoris LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned) FI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2023-001004-33 Sponsor Protocol Number: CLCZ696B2319E2 Start Date*: 2025-01-20
    Sponsor Name:Novartis Pharmaceuticals
    Full Title: A Safety Study of Sacubitril/​Valsartan in Japanese Pediatric Patients With Heart Failure Due to Systemic Left Ventricle Systolic Dysfunction Who Have Completed CLCZ696B2319E1 Study
    Medical condition: Heart Failure
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10019280 Heart failures HLGT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2018-000298-65 Sponsor Protocol Number: BAY1021189/19334 Start Date*: 2018-06-11
    Sponsor Name:Bayer AG
    Full Title: A randomized parallel-group, placebo-controlled, double-blind, multi-center trial to eValuate the effIcacy and safeTy of the orAL sGC stImulator vericiguaT to improve phYsical functioning in activi...
    Medical condition: Heart failure and preserved ejection fraction
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10008908 Chronic heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) PT (Completed) AT (Completed) ES (Completed) HU (Completed) BG (Completed) GR (Completed) PL (Completed) IT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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