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Clinical trials for Cardiovascular Diseases AND Acute Myocardial Infarction AND Heart Diseases

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44398   clinical trials with a EudraCT protocol, of which   7410   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    224 result(s) found for: Cardiovascular Diseases AND Acute Myocardial Infarction AND Heart Diseases. Displaying page 5 of 12.
    « Previous 1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2018-000916-75 Sponsor Protocol Number: REC-DUT-002 Start Date*: 2018-06-07
    Sponsor Name:RECARDIO Inc.
    Full Title: A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Safety and Efficacy Study of Dutogliptin in Combination with Filgrastim in Early Recovery Post-Myocardial Infarction
    Medical condition: Acute myocardial infarction, acute myocardial ischemia, STEMI ST elevation myocardial infarction
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) AT (Prematurely Ended) BE (Completed) NL (Prematurely Ended) PL (Prematurely Ended) BG (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-000664-31 Sponsor Protocol Number: D169DC00001 Start Date*: 2020-08-12
    Sponsor Name:AstraZeneca AB
    Full Title: A Registry-based, Randomised, Double-blind, Placebo-Controlled Cardiovascular Outcomes Trial to Evaluate the Effect of Dapagliflozin on Cardiometabolic Outcomes in Patients without Diabetes with Ac...
    Medical condition: Acute Myocardial Infarction, Heart failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2011-005095-41 Sponsor Protocol Number: ARMYDAPRO240 Start Date*: 2011-09-27
    Sponsor Name:UNIVERSITA' CAMPUS BIOMEDICO
    Full Title: prospective randomized study Armyda Pro 240
    Medical condition: patients treated with clopidogrel candidates for coronary angioplasty for ST-segment elevation acute coronary syndrome or stable angina
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10007541 Cardiac disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-024616-33 Sponsor Protocol Number: TRO40303CLEQ1491-1 Start Date*: 2011-08-04
    Sponsor Name:TROPHOS SA
    Full Title: Phase II, multicenter, randomized, double-blind, placebo controlled study to assess safety and efficacy of TRO40303 for reduction of reperfusion injury in patients undergoing Percutaneous Coronary ...
    Medical condition: Treatment for cardiac reperfusion injury in patients undergoing PCI( Percutaneous coronary intervention) to treat an AMI (Acute Myocardial Infarction) and to assess safety as well as the ability of...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10000930 Acute myocardial infarction, unspecified site, initial episode of care LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-001959-11 Sponsor Protocol Number: CL3-16257-056 Start Date*: 2005-04-20
    Sponsor Name:Institut de Recherches Internationales
    Full Title: Effects of ivabradine on cardiovascular events in patients with stable coronary artery disease and left ventricular systolic dysfunction. A three-year randomised double-blind placebo-controlled int...
    Medical condition: Coronary artery disease
    Disease: Version SOC Term Classification Code Term Level
    7.0 10011078 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) LT (Completed) FI (Completed) LV (Completed) IT (Completed) CZ (Completed) SK (Completed) GB (Completed) DK (Completed) AT (Completed) SE (Completed) EE (Completed) DE (Completed) IE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2011-002824-42 Sponsor Protocol Number: SPIRI-201 Start Date*: 2012-04-17
    Sponsor Name:Stealth Peptides Inc.
    Full Title: A Phase 2a, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Safety, Tolerability and Efficacy of Intravenous Bendavia™ (MTP-131) on Reperfusion Injury in Patients Treated with St...
    Medical condition: Reperfusion injury in ST-segment Elevation Myocardial Infarction
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004849 10064345 ST segment elevation myocardial infarction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2012-003423-37 Sponsor Protocol Number: PRIME Start Date*: 2012-07-31
    Sponsor Name:UNIVERSITA' CAMPUS BIOMEDICO
    Full Title: Prospective randomized study ARMYDA PRIME
    Medical condition: patients with acute myocardial infarction with ST elevation (STEMI)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10007541 Cardiac disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-002799-42 Sponsor Protocol Number: CAPstatin2013 Start Date*: 2014-03-27
    Sponsor Name:Dipartimento di Medicina Interna e Specialità Mediche - Policlinico Umberto I - Sapienza Università di Roma
    Full Title: Statins in the prevention of myocardial damage in pneumonia
    Medical condition: Patients hospitalized with community-acquired pneumonia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-005744-34 Sponsor Protocol Number: iCHF-2 Start Date*: 2019-01-03
    Sponsor Name:University Medical Centre Hamburg-Eppendorf
    Full Title: Randomized, Double-Blinded, Controlled Trial of Intravenous Iron in Patients With Cardiovascular Disease and Concomitant Iron Deficiency
    Medical condition: Patients With Cardiovascular Disease and Concomitant Iron Deficiency Cohort A: Acute myocardial infarction (AMI) Cohort B: Paroxysmal atrial fibrillation or persitent atrial fibrillation (AF) Coho...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10071667 Persistent atrial fibrillation LLT
    20.0 10007541 - Cardiac disorders 10034039 Paroxysmal atrial fibrillation LLT
    20.0 10022891 - Investigations 10050527 Ejection fraction PT
    20.0 10007541 - Cardiac disorders 10000891 Acute myocardial infarction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-002708-38 Sponsor Protocol Number: 131313 Start Date*: 2020-10-26
    Sponsor Name:Department of Medical Science Gothenburg University
    Full Title: Optimized pharmacological treatment for broken heart (takotsubo) syndrome
    Medical condition: The medical condition is acute heart failure (Takotsubo syndrome)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2017-001499-43 Sponsor Protocol Number: TACSI-01 Start Date*: 2017-11-23
    Sponsor Name:Sahlgrenska University Hospital
    Full Title: Dual antiplatelet therapy with ticagrelor and acetylsalicylic acid (ASA) vs. ASA only after isolated coronary artery bypass grafting in patients with acute coronary syndrome (TACSI trial)
    Medical condition: Coronary artery multi-vessel disease and left main stenosis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10011098 Coronary bypass LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Trial now transitioned) NO (Trial now transitioned) FI (Trial now transitioned) DK (Trial now transitioned) IS (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-004565-14 Sponsor Protocol Number: 20170625 Start Date*: 2019-09-13
    Sponsor Name:Amgen Inc.
    Full Title: A Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Impact of Evolocumab on Major Cardiovascular Events in Patients at High Cardiovascular Risk Without Prior Myocardia...
    Medical condition: Dyslipidemia
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004861 10058110 Dyslipidemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned) NL (Trial now transitioned) GB (GB - no longer in EU/EEA) SE (Trial now transitioned) HU (Trial now transitioned) DK (Trial now transitioned) DE (Trial now transitioned) PL (Trial now transitioned) BG (Trial now transitioned) ES (Ongoing) PT (Trial now transitioned) FI (Trial now transitioned) AT (Trial now transitioned) LT (Trial now transitioned) LV (Trial now transitioned) EE (Trial now transitioned) SK (Trial now transitioned) GR (Trial now transitioned) IT (Trial now transitioned) RO (Trial now transitioned) IS (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2014-005569-58 Sponsor Protocol Number: BAY59-7939/17454 Start Date*: 2015-09-23
    Sponsor Name:Bayer AG
    Full Title: An international, multicenter, randomized, double-blind, placebo-controlled phase 3 trial investigating the efficacy and safety of Rivaroxaban to reduce the risk of major thrombotic vascular event...
    Medical condition: Peripheral artery disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10053375 Peripheral revascularization LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) AT (Completed) ES (Completed) HU (Completed) GB (Completed) FR (Completed) PT (Completed) SE (Completed) BE (Completed) BG (Completed) DK (Completed) DE (Completed) NL (Completed) PL (Completed) SK (Completed) LT (Completed) LV (Completed) RO (Completed) EE (Completed) FI (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2021-001534-19 Sponsor Protocol Number: APHP200015 Start Date*: 2021-05-21
    Sponsor Name:AP-HP/DRCI
    Full Title: Direct oral Anticoagulants for Prevention of lEft ventRIcular Thrombus after anterior acute myocardial InFarction
    Medical condition: Left ventricular (LV) thrombus after acute myocardial infarction (AMI)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-002020-25 Sponsor Protocol Number: 052017 Start Date*: 2018-08-31
    Sponsor Name:Odense University Hospital
    Full Title: ANGIOTENSIN–NEPRILYSIN INHIBITION IN DIASTOLIC DYSFUNCTION AFTER AMI
    Medical condition: Diastolic dysfunction after acute myocardial infarction
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004849 10076396 Heart failure with preserved ejection fraction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2021-002006-27 Sponsor Protocol Number: CKJX839B12302 Start Date*: 2021-11-15
    Sponsor Name:Novartis Pharma AG
    Full Title: A randomized, double-blind, placebo -controlled, multicenter trial, assessing the impact of inclisiran on major adverse cardiovascular events in participants with established cardiovascular disease...
    Medical condition: Atherosclerotic cardiovascular disease (ASCVD)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004866 10051615 Atherosclerotic cardiovascular disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned) SK (Trial now transitioned) PT (Trial now transitioned) LT (Trial now transitioned) NL (Trial now transitioned) IT (Trial now transitioned) AT (Trial now transitioned) LV (Trial now transitioned) HU (Trial now transitioned) SE (Trial now transitioned) DK (Trial now transitioned) BE (Trial now transitioned) SI (Trial now transitioned) BG (Trial now transitioned) HR (Trial now transitioned) NO (Trial now transitioned) PL (Trial now transitioned) FI (Trial now transitioned) GR (Trial now transitioned) IS (Trial now transitioned) RO (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2010-020497-41 Sponsor Protocol Number: ANG.AMI-IC001 Start Date*: 2013-02-13
    Sponsor Name:Mesoblast, Inc.
    Full Title: A prospective, double blind, randomized, placebo-controlled clinical trial of intracoronary infusion of immunoselected, bone marrow-derived Stro3 mesenchymal precursor cells (MPC) in the treatment ...
    Medical condition: ST-elevation myocardial infarction
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10064345 ST segment elevation myocardial infarction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) BE (Completed) NL (Completed) DK (Completed) SE (Completed) CZ (Completed) AT (Prematurely Ended) PL (Completed) IT (Prematurely Ended) ES (Completed) PT (Completed)
    Trial results: View results
    EudraCT Number: 2014-005407-24 Sponsor Protocol Number: KKIKEM Start Date*: 2015-02-27
    Sponsor Name:IKEM
    Full Title: Effect of early administration of eplerenone in patients after acute myocardial infarction
    Medical condition: Verify the efficacy of early administration of eplerenone in relation to the development of pathological remodeling of the myocardium in patients after myocardial infarction.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-002004-24 Sponsor Protocol Number: CV185-316 Start Date*: 2017-02-08
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: An Open-label, 2 x 2 Factorial, Randomized Controlled, Clinical Trial to Evaluate the Safety of Apixaban vs. Vitamin K Antagonist and Aspirin vs. Aspirin Placebo in Patients with Atrial Fibrillatio...
    Medical condition: Atrial Fibrillation and Acute Coronary Syndrome and/or Percutaneous Coronary Intervention
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    20.0 10007541 - Cardiac disorders 10051592 Acute coronary syndrome PT
    20.0 10042613 - Surgical and medical procedures 10065608 Percutaneous coronary intervention PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed) BG (Completed) AT (Completed) BE (Completed) DK (Completed) NL (Completed) PL (Completed) PT (Completed) ES (Completed) CZ (Completed) DE (Completed) SE (Completed) SK (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-001642-26 Sponsor Protocol Number: LRD.2016.STREAM2 Start Date*: 2017-10-02
    Sponsor Name:Leuven Research & Development (LRD) at University of Leuven, Belgium
    Full Title: STREAM-2 (STrategic Reperfusion in elderly patients Early After Myocardial Infarction)
    Medical condition: ST-elevation myocardial infarction within 3 hours of onset of symptoms
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000011652 10064345 ST segment elevation myocardial infarction LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: ES (Completed) RO (Completed)
    Trial results: View results
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    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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