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Clinical trials for neuropathy

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44398   clinical trials with a EudraCT protocol, of which   7410   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    741 result(s) found for: neuropathy. Displaying page 7 of 38.
    EudraCT Number: 2009-011535-12 Sponsor Protocol Number: Fx1A-303 Start Date*: 2009-08-26
    Sponsor Name:Pfizer Inc.
    Full Title: Open-Label Safety and Efficacy Evaluation of Fx-1006A in Patients with Transthyretin Amyloidosis
    Medical condition: Transthyretin Amyloidosis (ATTR)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10010331 - Congenital, familial and genetic disorders 10057949 Familial amyloid polyneuropathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) SE (Completed) FR (Completed) PT (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2013-001435-48 Sponsor Protocol Number: 464/11 Start Date*: 2013-06-05
    Sponsor Name:Keele University
    Full Title: The clinical and cost effectiveness of a steroid injection versus a night splint for Carpal Tunnel Syndrome: a pragmatic randomised trial in primary care
    Medical condition: Carpal Tunnel Syndrome (CTS)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10007697 Carpal tunnel syndrome PT
    20.0 10029205 - Nervous system disorders 10007697 Carpal tunnel syndrome PT
    20.0 10029205 - Nervous system disorders 10052414 Unilateral carpal tunnel syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-003519-24 Sponsor Protocol Number: ALN-TTR02-008 Start Date*: 2019-03-12
    Sponsor Name:Alnylam Pharmaceuticals, Inc.
    Full Title: An Open-label Study to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of Patisiran-LNP in Patients with Hereditary Transthyretin-mediated Amyloidosis (hATTR amyloidosis) with Disease Progressi...
    Medical condition: Hereditary Transthyretin-mediated Amyloidosis (hATTR amyloidosis)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10007509 Cardiac amyloidosis PT
    20.0 10010331 - Congenital, familial and genetic disorders 10019889 Hereditary neuropathic amyloidosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) FR (Completed) PT (Completed) DE (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-003197-57 Sponsor Protocol Number: A0081181 Start Date*: 2012-11-09
    Sponsor Name:Pfizer Worldwide Research and Development
    Full Title: A MULTIPLE DOSE PHARMACOKINETIC OPEN-LABEL STUDY OF PREGABALIN (LYRICA) IN HEALTHY LACTATING WOMEN
    Medical condition: neuropathic pain associated with diabetic peripheral neuropathy postherpetic neuralgia neuropathic pain related to spinal cord injury (US), fibromyalgia (US, JP) treatment of central and periphe...
    Disease: Version SOC Term Classification Code Term Level
    15.1 10029205 - Nervous system disorders 10028005 Motor peripheral neuropathy LLT
    15.1 10029205 - Nervous system disorders 10054095 Neuropathic pain LLT
    15.1 10029205 - Nervous system disorders 10036376 Post herpetic neuralgia PT
    15.1 10029205 - Nervous system disorders 10067547 Diabetic peripheral neuropathic pain LLT
    15.1 10022117 - Injury, poisoning and procedural complications 10041552 Spinal cord injury PT
    15.1 10037175 - Psychiatric disorders 10018075 Generalised anxiety disorder PT
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-002987-17 Sponsor Protocol Number: ALN-TTR02-004 Start Date*: 2013-11-25
    Sponsor Name:Alnylam Pharmaceuticals, Inc
    Full Title: APOLLO: A Phase 3 Multicenter, Multinational, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Patisiran (ALN-TTR02) in Transthyretin (TTR)-Mediated Polyneu...
    Medical condition: Transthyretin mediated amyloidosis (ATTR)
    Disease: Version SOC Term Classification Code Term Level
    19.0 10007541 - Cardiac disorders 10007509 Cardiac amyloidosis PT
    19.0 10010331 - Congenital, familial and genetic disorders 10019889 Hereditary neuropathic amyloidosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) ES (Completed) PT (Completed) IT (Completed) DE (Completed) NL (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-000991-27 Sponsor Protocol Number: 802NP206 Start Date*: 2018-02-27
    Sponsor Name:Biogen Idec Research Limited
    Full Title: A Phase 2 Placebo-Controlled, Double-Blind, Enriched Enrollment Randomized Withdrawal Study to Evaluate the Efficacy and Safety of BIIB074 (Vixotrigine) in Treating Pain Experienced by Subjects Wit...
    Medical condition: Treating Pain Experienced by Subjects With Confirmed Small Fibre Neuropathy That is Idiopathic or Associated With Diabetes Mellitus
    Disease: Version SOC Term Classification Code Term Level
    20.1 10029205 - Nervous system disorders 10073928 Small fibre neuropathy PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) CZ (Prematurely Ended) GR (Completed) HU (Prematurely Ended) ES (Prematurely Ended) DK (Prematurely Ended) BG (Prematurely Ended) NL (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-002098-23 Sponsor Protocol Number: ALN-TTRSC02-002 Start Date*: 2019-05-09
    Sponsor Name:Alnylam Pharmaceuticals, Inc.
    Full Title: HELIOS-A: A Phase 3 Global, Randomized, Open-label Study to Evaluate the Efficacy and Safety of ALN-TTRSC02 in Patients with Hereditary Transthyretin Amyloidosis (hATTR Amyloidosis)
    Medical condition: Hereditary transthyretin-mediated amyloidosis (hATTR amyloidosis)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10007509 Cardiac amyloidosis PT
    20.0 10010331 - Congenital, familial and genetic disorders 10019889 Hereditary neuropathic amyloidosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) PT (Trial now transitioned) GB (GB - no longer in EU/EEA) BG (Trial now transitioned) ES (Ongoing) BE (Trial now transitioned) GR (Completed) NL (Trial now transitioned) CY (Trial now transitioned) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2007-006515-23 Sponsor Protocol Number: STC- Progesterone -2007 Start Date*: 2008-01-02
    Sponsor Name:AZIENDA OSPEDALIERA SENESE
    Full Title: Randomized clinical trial for the local therapy of carpal tunnel syndrome: cortisone vs progesterone
    Medical condition: - mild-to-moderate idiopathic carpal tunnel syndrome
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007697 Carpal tunnel syndrome LLT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-002603-29 Sponsor Protocol Number: ALN-TTRSC-005 Start Date*: 2015-12-01
    Sponsor Name:Alnylam Pharmaceuticals, Inc
    Full Title: An Open-Label Study To Evaluate The Efficacy And Safety Of Revusiran In Patients With Transthyretin-Mediated Familial Amyloidotic Polyneuropathy With Disease Progression Post Orthotopic Liver Trans...
    Medical condition: Transthyretin (TTR)-mediated Familial Amyloidotic Polyneuropathy (FAP)
    Disease: Version SOC Term Classification Code Term Level
    18.0 10010331 - Congenital, familial and genetic disorders 10019889 Hereditary neuropathic amyloidosis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed) PT (Completed) ES (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-002843-18 Sponsor Protocol Number: AS3201-G000-291 Start Date*: 2009-09-21
    Sponsor Name:Eisai Limited
    Full Title: A 2-year, Randomized, Double-blind, Placebo-controlled, Multi-center, Phase II-III Study to Evaluate the Efficacy and Safety of Oral Ranirestat (40 and 80 mg) in Mild to Moderate Diabetic Sensorimo...
    Medical condition: Diabetic Sensorimotor Polyneuropathy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012685 Diabetic polyneuropathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) HU (Completed) EE (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-000873-56 Sponsor Protocol Number: CARPA2013 Start Date*: 2013-07-04
    Sponsor Name:Federico Diaz González
    Full Title: Randomized, two paralel groups, open clinical trial stratified by severity to stimate the cost-effectivity of surgical vs corticosteroid injection treatment on carpal tunnel syndrome
    Medical condition: Carpal tunnel syndrome
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10007697 Carpal tunnel syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-002289-62 Sponsor Protocol Number: ST200-SSMA-14-001 Start Date*: 2014-09-11
    Sponsor Name:SIGMA-TAU, Industrie Farmaceutiche Riunite S.p.A.
    Full Title: Electroneurographic and clinical evaluation in patients with mild / moderate Carpal Tunnel Syndrome , following conservative pharmacological treatment with Nicetile®.
    Medical condition: Carpal Tunnel Syndrome
    Disease: Version SOC Term Classification Code Term Level
    17.0 10029205 - Nervous system disorders 10007697 Carpal tunnel syndrome PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-002361-36 Sponsor Protocol Number: ONCOSUR-2012-01 Start Date*: 2012-10-17
    Sponsor Name:ONCOSUR
    Full Title: Neurotoxicity characterization phase II randomized study of nab-paclitaxel versus conventional paclitaxel as first-line therapy of metastatic HER2-negative breast cancer.
    Medical condition: Metastatic HER2-negative breast cancer
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10027475 Metastatic breast cancer LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2015-002624-31 Sponsor Protocol Number: NL53861.068.15 Start Date*: 2015-12-23
    Sponsor Name:Maastricht UMC
    Full Title: Intravenous immunoglobulin therapy for small fiber neuropathy: a randomised, double-blind, placebo-controlled study on efficacy and safety.
    Medical condition: Skin-biopsy proven small fiber neuropathy without an underlying cause
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-003694-34 Sponsor Protocol Number: 2-HIT Start Date*: 2017-10-25
    Sponsor Name:Ziekenhuis Oost-Limburg
    Full Title: Onset and duration of Forearm nerve blockade performed with a single distal injection versus sequential injections at distal and proximal locations alongside the nerves: a blinded randomized contro...
    Medical condition: Dupuytren contrature and Carpal Tunnel syndrome
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10013873 Dupuytren's contracture operation PT
    20.0 10029205 - Nervous system disorders 10007697 Carpal tunnel syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-022873-32 Sponsor Protocol Number: MRK008b-2010 Start Date*: 2010-12-14
    Sponsor Name:Analgesic Solutions
    Full Title: An Enriched Enrollment, Double Blind, Placebo-Controlled, Parallel Group, Randomized Withdrawal Trial to Evaluate the Efficacy, Tolerability and Safety of Etoricoxib (Arcoxia) in Patients with Mode...
    Medical condition: Patients with Neuropathic Pain. In the first instance, the investigator will aim to recruit patients with post herpetic neuralgia. If insufficient patients with post herpetic neuralgia are recruite...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-004746-17 Sponsor Protocol Number: 17HH4283 Start Date*: 2018-03-05
    Sponsor Name:Joint Research Compliance Office, Imperial College London and Imperial College Healthcare NHS Trust
    Full Title: Pain relief with disease modification by Capsaicin 8% patch: a clinical study in Diabetic Peripheral Neuropathy
    Medical condition: Diabetic painful neuropathy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2012-000128-16 Sponsor Protocol Number: 2011-003 Start Date*: 2012-07-30
    Sponsor Name:Onyx Therapeutics, Inc.
    Full Title: A Randomized, Open-label, Phase 3 Study of Carfilzomib Plus Dexamethasone vs Bortezomib Plus Dexamethasone in Patients With Relapsed Multiple Myeloma
    Medical condition: Multiple myeloma
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004864 10028228 Multiple myeloma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) GB (Completed) HU (Completed) DE (Completed) IT (Completed) ES (Completed) SK (Completed) GR (Completed) CZ (Completed) AT (Completed) BG (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2013-004600-19 Sponsor Protocol Number: PAINTER01 Start Date*: 2014-01-21
    Sponsor Name:Azienda Ospedaliera Fatebenefratelli e Oftalmico - Milano, Italy
    Full Title: Multicenter, interventional, single-arm, phase IV study evaluating tolerability of Eribulin and its relationship with a set of polymorphisms in an unselected population of female patients with meta...
    Medical condition: Patients with metastatic breast cancer
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-002968-49 Sponsor Protocol Number: BN43118 Start Date*: 2022-06-24
    Sponsor Name:Roche Farma S. A. U. que realiza el ensayo en España y que actúa como representante F. Hoffmann-La Roche Ltd
    Full Title: A PHASE III, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY TO EVALUATE THE EFFICACY, SAFETY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF CROVALIMAB IN PATIENTS WITH GUILLAIN-BARRÉ S...
    Medical condition: Guillain-Barré syndrome (GBS)
    Disease: Version SOC Term Classification Code Term Level
    22.1 10029205 - Nervous system disorders 10018767 Guillain-Barre syndrome PT
    21.1 10029205 - Nervous system disorders 10018766 Guillain Barre syndrome LLT
    21.1 10029205 - Nervous system disorders 10042812 Syndrome Guillain-Barre LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
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