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Clinical trials for Neovascularization

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
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    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    171 result(s) found for: Neovascularization. Displaying page 8 of 9.
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    EudraCT Number: 2019-003851-12 Sponsor Protocol Number: 20968 Start Date*: 2020-06-25
    Sponsor Name:Bayer AG
    Full Title: Randomized, Double-Masked, Active-Controlled, Phase 3 Study of the Efficacy and Safety of High Dose Aflibercept in Patients With Neovascular Age-Related Macular Degeneration
    Medical condition: Neovascular Age-Related Macular Degeneration
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10071129 Neovascular age-related macular degeneration PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) LT (Completed) LV (Completed) PT (Completed) EE (Completed) AT (Completed) FR (Completed) SK (Completed) BG (Completed) CZ (Completed) GB (GB - no longer in EU/EEA) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-001961-20 Sponsor Protocol Number: FYB201-C2015-01-P3 Start Date*: 2015-11-24
    Sponsor Name:Bioeq GmbH
    Full Title: Efficacy and safety of the biosimilar ranibizumab FYB201 in comparison to Lucentis in patients with neovascular age-related macular degeneration (COLUMBUS-AMD)
    Medical condition: Subfoveal neovascular age-related macular degeneration
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10071129 Neovascular age-related macular degeneration PT
    20.0 100000116602 10067791 Wet macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) AT (Completed) DE (Completed) HU (Completed) ES (Completed) FR (Completed) GB (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2020-000681-42 Sponsor Protocol Number: CoRaLa_II Start Date*: 2020-08-24
    Sponsor Name:Justus-Liebig University Gießen
    Full Title: Long-term need of ranibizumab injections with or without early targeted peripheral laser photocoagulation for treatment of macular edema due to central retinal vein occlusion
    Medical condition: Macular edema due to central retinal vein occlusion
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004853 10054467 Macular edema LLT
    20.0 100000004853 10007972 Central retinal vein occlusion LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned) AT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-005364-57 Sponsor Protocol Number: HLX04-O-wAMD Start Date*: 2021-04-06
    Sponsor Name:Shanghai Henlius Biotech. Inc.
    Full Title: A Phase 3, Two-part (Open-label Followed by Randomized Double-masked Active Controlled) Study to Compare the Efficacy and Safety of HLX04-O Administered by Intravitreal Injection with ranibizumab i...
    Medical condition: Wet Age-related Macular Degeneration (wAMD)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004853 10075568 Wet age-related macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LV (Completed) HU (Completed) CZ (Prohibited by CA) PL (Completed) ES (Ongoing) SK (Completed) BG (Completed) DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006358-86 Sponsor Protocol Number: ATG003-201 Start Date*: 2007-04-27
    Sponsor Name:CoMentis, Inc., USA
    Full Title: A PHASE II RANDOMIZED, DOUBLE-MASKED, STUDY COMPARING THE SAFETY AND EFFICACY OF ATG003 (MECAMYLAMINE HCL) 1.0% and 0.3% OPHTHALMIC SOLUTIONS TO PLACEBO IN PATIENTS WITH NEOVASCULAR ("WET") AGE-REL...
    Medical condition: Neovascular ("wet") Age-related Macular Degeneration (NV- AMD)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064930 Age-related macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-004721-23 Sponsor Protocol Number: VIBERA Start Date*: 2007-11-14
    Sponsor Name:Klinikum Bremen-Mitte gGmbH
    Full Title: Prevention of vision loss in patients with age-related neovascular macular degeneration by intravitreal injection of bevacizumab and ranibizumab in a typical outpatient setting
    Medical condition: age-related neovascular macular degeneration
    Disease: Version SOC Term Classification Code Term Level
    14.0 10015919 - Eye disorders 10064930 Age-related macular degeneration PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-006014-18 Sponsor Protocol Number: 1419 Start Date*: 2005-12-15
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Macular structure and function after intravitreal injection of bevacizumab for wet macular degeneration a interventional study.
    Medical condition: Macular degeneration
    Disease: Version SOC Term Classification Code Term Level
    6.1 10025409 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-004292-35 Sponsor Protocol Number: 06NB37 Start Date*: 2007-03-08
    Sponsor Name:Kings College Hospital NHS Foundation Trust
    Full Title: A pillot study to examine the safety and efficacy of intravitreal ranubizimab/dexamethasone administration and oral minocycline in addition to Visudyne (verteporfin) photdynamic therapy for subfove...
    Medical condition: Age related macular degeneration
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064930 Age-related macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-001262-28 Sponsor Protocol Number: MSC-TENDO-2015 Start Date*: 2017-08-21
    Sponsor Name:Institut de Terapia Regenerativa Tissular S.L. (ITRT)
    Full Title: Treatment of Refractory Patellar Tendinopathy with MSV *. Comparative study with P-PRP *MSV are bone marrow autologous mesenchymal stem cells, selected and cultured under Good manufacturing Practic...
    Medical condition: Patients diagnosed with patellar tendinopathy with a minimum of 4 months evolution and have presented two acute episodes, refractory to standard treatments present a gap equal or greater than 3 mm ...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10034123 Patellar tendinitis LLT
    Population Age: Adults Gender: Male
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-003853-97 Sponsor Protocol Number: PNB1 Start Date*: 2007-10-18
    Sponsor Name:Central Manchester University Hospitals NHS Foundation Trust
    Full Title: A 23-month randomised, masked, prospective phase IV study assessing the safety and efficacy of two alternative treatment regimes using Bevacizumab (AvastinTM) to treat patients with subfoveal and j...
    Medical condition: "wet" or "exudative" age-related macular degeneration (AMD)
    Disease: Version SOC Term Classification Code Term Level
    14.0 10015919 - Eye disorders 10015902 Exudative senile macular degeneration of retina LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-014280-38 Sponsor Protocol Number: 09OY006 Start Date*: 2009-11-13
    Sponsor Name:Nottingham University Hospitals NHS Trust
    Full Title: A randomised controlled trial of standard and low dose Avastin® for Neovascular Macular Degeneration in the East Midlands
    Medical condition: Neovascular ("wet") age-related macular degeneration
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004853 10015902 Exudative senile macular degeneration of retina LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-005684-26 Sponsor Protocol Number: Version_1_10072006 Start Date*: 2007-09-06
    Sponsor Name:Universitätsklinik für Augenheilkunde und Optometrie, AKH Wien
    Full Title: Identification and Quantification of Cytokines in Anti-VEGF Therapy and Genetic Risk Factors in Exsudative Age-related Macular Degeneration
    Medical condition: Exsudative age-related macular degeneration (AMD), cataract, macular pucker
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015902 Exudative senile macular degeneration of retina LLT
    9.1 10007739 Cataract LLT
    9.1 10025417 Macular puckering of retina LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2012-004952-12 Sponsor Protocol Number: 4429-202 Start Date*: 2013-04-05
    Sponsor Name:Acucela Inc.
    Full Title: A Phase 2b/3 Multicenter, Randomized, Double-Masked, Dose-Ranging Study Comparing the Efficacy and Safety of Emixustat Hydrochloride (ACU-4429) with Placebo for the Treatment of Geographic Atrophy ...
    Medical condition: Geographic atrophy associated with dry age-related macular degeneration
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004853 10063947 Geographic atrophy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-017429-21 Sponsor Protocol Number: ZAPA-01 Start Date*: 2010-03-22
    Sponsor Name:Miguel Ángel Zapata. Oftalmología. Hospital vall d'Hebron
    Full Title: ENSAYO CLÍNICO, ABIERTO, DE SEGURIDAD Y EFICACIA DE ADALIMUMAB INTRAVÍTREO EN PACIENTES CON NEOVASCULARIZACIÓN COROIDEA SECUNDARIA A DEGENERACIÓN MACULAR ASOCIADA A LA EDAD EN PACIENTES NO RESPONDE...
    Medical condition: Degeneración macular asociada a la edad en su forma exudativa
    Disease: Version SOC Term Classification Code Term Level
    12.1 10015902 Exudative senile macular degeneration of retina LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2019-000946-37 Sponsor Protocol Number: 2019-06 Start Date*: 2020-11-30
    Sponsor Name:Assistance Publique-Hôpitaux de Marseille
    Full Title: Molecular imaging exploration of ocular angiogenic activity and evaluation of its relevance in the therapeutic follow-up of AMD patients.
    Medical condition: Age-related macular degeneration
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10025409 Macular degeneration PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2012-000765-20 Sponsor Protocol Number: ANTIVEGFVEP Start Date*: 2015-11-27
    Sponsor Name:Kuopion yliopistollinen sairaala/silmätautien poliklinikka
    Full Title: The Effect of Intravitreal Bevacizumab Injections in Patients with Macular Oedema Caused by AMD, CRVO or DME on the Plasticity of Nerves Studied by Visual Evoked Potentials
    Medical condition: Wet age-related macular degeneration, diabetic macular edema, central retinal vein occlusion
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004853 10012675 Diabetic macular retinopathy LLT
    18.1 100000004853 10007972 Central retinal vein occlusion LLT
    18.1 100000004853 10015902 Exudative senile macular degeneration of retina LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-003261-14 Sponsor Protocol Number: R01 Start Date*: 2006-08-28
    Sponsor Name:Retinaklinikken Omnia
    Full Title: A randomized pilot study comparing the safety and efficacy of intravireal triamcinolone acetonide given 7 days prior to or after Photodynamic therapy with Visudyne in patients with subfoveal choroi...
    Medical condition: Patients with age-related macular degeneration
    Disease: Version SOC Term Classification Code Term Level
    8.1 10025409 Macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-000168-32 Sponsor Protocol Number: NL51705.000.15 Start Date*: 2016-07-13
    Sponsor Name:University Medical Center Utrecht
    Full Title: Mesenchymal stem cells for Angiogenesis and Neovascularization in digital Ulcers of Systemic sclerosis
    Medical condition: systemic sclerosis
    Disease: Version SOC Term Classification Code Term Level
    18.0 10028395 - Musculoskeletal and connective tissue disorders 10042953 Systemic sclerosis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-000120-33 Sponsor Protocol Number: BAY86-5321/16598 Start Date*: 2015-08-26
    Sponsor Name:Bayer HealthCare AG
    Full Title: An open-label, randomized, active-controlled, parallel-group, Phase-3b study of the efficacy, safety, and tolerability of 2 mg aflibercept administered by intravitreal injections using two differen...
    Medical condition: Neovascular Age-Related Macular Degeneration (nAMD)
    Disease: Version SOC Term Classification Code Term Level
    18.1 10015919 - Eye disorders 10071129 Neovascular age-related macular degeneration PT
    18.1 10015919 - Eye disorders 10015919 Eye disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) CZ (Completed) SK (Completed) PT (Completed) LT (Completed) AT (Completed) GB (GB - no longer in EU/EEA) ES (Completed) DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2021-003651-42 Sponsor Protocol Number: AVT06-GL-C01 Start Date*: 2022-04-14
    Sponsor Name:Alvotech Swiss AG
    Full Title: A Randomized, Double-masked, Parallel-group, Multicenter Clinical Study to Evaluate the Efficacy and Safety of AVT06 Compared with EU-Eylea® in Subjects with Neovascular (wet) Age related Macular D...
    Medical condition: Neovascular (wet) Age-related Macular Degeneration
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10071129 Neovascular age-related macular degeneration PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LV (Completed) SK (Completed) CZ (Completed) HU (Completed) BG (Completed) LT (Completed)
    Trial results: (No results available)
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