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Clinical trials for Central corneal thickness

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    25 result(s) found for: Central corneal thickness. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2019-003280-22 Sponsor Protocol Number: K-321-201 Start Date*: 2020-04-29
    Sponsor Name:Kowa Research Institute, Inc.
    Full Title: A Double-Masked, Randomised, Placebo-Controlled, Parallel-Group, 12-Week, Phase 2 Study to Investigate the Safety and Efficacy of Ripasudil (K-321) Eye Drops After Descemetorhexis in Patients wit...
    Medical condition: In Fuchs endothelial corneal dystrophy (FECD), there is an increased rate of loss of endothelial cells, starting in the centre of Descemet’s membrane and spreading to the periphery, resulting in ex...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10011005 Corneal dystrophy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-006456-14 Sponsor Protocol Number: K321301 Start Date*: 2023-05-10
    Sponsor Name:Kowa Research Institute, Inc.
    Full Title: A Double-Masked, Randomized, Placebo-Controlled, Parallel-Group, 12-Week Administration With Two-Week Gradual Dose Taper Phase and 38-Week Follow-Up Phase, Phase 3 Study to Investigate the Safety ...
    Medical condition: In Fuchs endothelial corneal dystrophy (FECD), there is an increased rate of loss of endothelial cells, starting in the centre of Descemet’s membrane and spreading to the periphery, resulting in ex...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10011005 Corneal dystrophy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing) DK (Trial now transitioned) ES (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2007-000295-16 Sponsor Protocol Number: LX201-01 Start Date*: 2007-07-27
    Sponsor Name:Lux Biosciences, Inc.
    Full Title: A MULTI-CENTER, PLACEBO-CONTROLLED, RANDOMIZED, PARALLEL-GROUP DOSE-RANGING STUDY TO ASSESS THE EFFICACY AND SAFETY OF LX201 FOR PREVENTION OF CORNEAL ALLOGRAFT REJECTION EPISODES AND GRAFT FAILURE...
    Medical condition: Patient after penetrating keratoplasty who are at increased immunological risk for corneal allograft rejection episodes and/or graft failure
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011017 Corneal graft rejection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000294-33 Sponsor Protocol Number: LX201-02 Start Date*: 2007-07-27
    Sponsor Name:Lux Biosciences, Inc.
    Full Title: A MULTI-CENTER, PLACEBO-CONTROLLED, RANDOMIZED, PARALLEL-GROUP, DOSE-RANGING STUDY TO ASSESS THE EFFICACY AND SAFETY OF LX201 IMPLANTATION FOR THE PREVENTION OF CORNEAL ALLOGRAFT REJECTION EPISODES...
    Medical condition: Patient after penetrating keratoplasty who have experienced one or more rejection episodes
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011017 Corneal graft rejection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-000174-25 Sponsor Protocol Number: 101090401IN Start Date*: 2023-03-17
    Sponsor Name:SANTEN INCORPORATED
    Full Title: A Phase IIa, Randomized, Double-Masked, Placebo-Controlled, Parallel-Group, Multicenter Study Assessing the Efficacy and Safety of STN1010904 Ophthalmic Suspension 0.03% and 0.1% Compared with Vehi...
    Medical condition: Fuchs Endothelial Corneal Dystrophy (FECD)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004850 10014823 Endothelial corneal dystrophy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-003408-15 Sponsor Protocol Number: DMEC Start Date*: 2021-06-14
    Sponsor Name:Oslo University Hospital
    Full Title: A randomized clinical two-arm trial comparing inflammation and cystoid macular edema for the medication regimens postoperative topical NSAIDs and steroids to only postoperative topical steroids in ...
    Medical condition: Corneal disease/opacification treated with corneal endothelial transplantation (DSAEK or DMEK surgery), and the medical treatment is anti-inflammatory eye drops to treat (and prevent) intraocular i...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2019-002535-28 Sponsor Protocol Number: 7343 Start Date*: Information not available in EudraCT
    Sponsor Name:Hôpitaux Universitaires de Strasbourg
    Full Title: Braking effect on myopia with atropine eye drops at 0.01%.
    Medical condition: Myopia
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-002490-19 Sponsor Protocol Number: UKER-FECD-RIPA-01 Start Date*: 2017-12-07
    Sponsor Name:Universitätsklinikum Erlangen
    Full Title: Prospective single-centre randomized observer-blind placebo-controlled parallel-group phase IIa clinical trial to investigate the safety and efficacy of ripasudil 0.4% eye drops after descemetorhex...
    Medical condition: Moderate to advanced Fuchs endothalial corneal dystrophy (FECD)
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004850 10062973 Fuchs' endothelial dystrophy LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-001460-11 Sponsor Protocol Number: 15/0599 Start Date*: 2016-06-30
    Sponsor Name:UCL CCTU
    Full Title: Corneal cross-linking versus standard care in children with keratoconus, a randomised, multicentre, observer-masked trial of efficacy and safety
    Medical condition: Patients with progressive keratoconus disease
    Disease: Version SOC Term Classification Code Term Level
    19.0 10015919 - Eye disorders 10023353 Keratoconus PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2011-006066-40 Sponsor Protocol Number: OZR-2011-23 Start Date*: 2012-05-15
    Sponsor Name:The Rotterdam Eye Hospital
    Full Title: The post-cataract inflammatory reaction with combination therapy of topical steroid and NSAID.
    Medical condition: Ocular inflammatory reaction after cataract surgery.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2010-020441-27 Sponsor Protocol Number: CORaLa Start Date*: 2011-02-23
    Sponsor Name:University of Leipzig Ritterstr. 26, 04109 Leipzig
    Full Title: Ranibizumab combined with selective peripheral laser photocoagulation for treatment of central retinal vein occlusion A randomized, controlled interventional phase 2b (proof of concept) study of ...
    Medical condition: macular edema secondary to non-ischemic central retinal vein occlusion
    Disease: Version SOC Term Classification Code Term Level
    14.0 10015919 - Eye disorders 10054467 Macular edema LLT
    14.0 10015919 - Eye disorders 10007972 Central retinal vein occlusion LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2013-005081-19 Sponsor Protocol Number: 1 Start Date*: 2014-07-10
    Sponsor Name:HOSPICES CIVILS DELYON
    Full Title: Phase II study evaluating the efficacy of aflibercept for the treatment of idiopathic choroidal neovascularization in young subjects: the INTUITION study
    Medical condition: idiopathic choroidal neovascularization
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004853 10060837 Choroidal neovascularization LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-002979-16 Sponsor Protocol Number: SPON UWCM 014 Start Date*: 2004-11-12
    Sponsor Name:CARDIFF UNIVERSITY
    Full Title: A Six-Week/Six-Week, Prospective, Randomised, Masked, Cross over, Primary Therapy Study comparing IOP Lowering Effects of Lumigan® and Xalatan® in Subjects with Primary Open Angle Glaucoma, Ocular...
    Medical condition: Primary open-angle glaucoma, Ocular hypertension, Pseudoexfoliation glaucoma or Pigment dispersion
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-000846-23 Sponsor Protocol Number: LT4032-301 Start Date*: 2018-09-16
    Sponsor Name:Laboratoires THEA
    Full Title: Efficacy and safety assessment of T4032 (unpreserved bimatoprost 0.01%) versus Lumigan® 0.01% in ocular hypertensive or glaucomatous patients.
    Medical condition: glaucoma, ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) GB (GB - no longer in EU/EEA) DE (Completed) LT (Completed) GR (Completed) BE (Completed) PL (Completed) ES (Completed) SK (Completed) CZ (Completed) LV (Completed) BG (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2017-002823-46 Sponsor Protocol Number: LT4030-201 Start Date*: 2018-09-11
    Sponsor Name:Laboratoires THÉA; Research and Development Department
    Full Title: Efficacy and safety assessment of T4030 eye drops (unpreserved fixed combination of bimatoprost 0.01% and timolol 0.1% or 0.5%) versus Ganfort® UD (Unit Dose) in ocular hypertensive or glaucomatous...
    Medical condition: Glaucoma, ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) PL (Completed) HU (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2018-002574-52 Sponsor Protocol Number: 1698-301-007 Start Date*: 2019-08-01
    Sponsor Name:Allergan Ltd.
    Full Title: A Phase 3b Study to Evaluate the Duration of Effect of Bimatoprost SR in Participants with Open-Angle Glaucoma or Ocular Hypertension
    Medical condition: Open-Angle Glaucoma or Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10030856 Open-angle glaucoma LLT
    20.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) DE (Trial now transitioned) IE (Trial now transitioned) SE (Completed) CZ (Trial now transitioned) HU (Completed) PL (Trial now transitioned) DK (Trial now transitioned) BG (Trial now transitioned) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-003979-18 Sponsor Protocol Number: LT4030-301 Start Date*: 2021-04-15
    Sponsor Name:Laboratoires THEA
    Full Title: Efficacy and Safety Assessment of T4030 Eye Drops versus Ganfort® UD in Ocular Hypertensive or Glaucomatous Patients.
    Medical condition: Primary open-angle glaucoma or Ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) PL (Completed) HU (Completed) BG (Completed) BE (Completed) ES (Ongoing) IT (Completed)
    Trial results: View results
    EudraCT Number: 2015-003631-34 Sponsor Protocol Number: 192024-095 Start Date*: 2017-01-12
    Sponsor Name:Allergan Limited
    Full Title: A Comparison of Bimatoprost SR to Selective Laser Trabeculoplasty in Patients with Open-Angle Glaucoma or Ocular Hypertension
    Medical condition: Open-angle glaucoma (OAG) or Ocular hypertension (OHT)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    20.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    20.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) ES (Temporarily Halted) CZ (Completed) FR (Completed) DK (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2015-002131-18 Sponsor Protocol Number: 192024-093 Start Date*: 2016-12-21
    Sponsor Name:Allergan Limited
    Full Title: A Comparison of Bimatoprost SR to Selective Laser Trabeculoplasty in Patients with Open-Angle Glaucoma or Ocular Hypertension
    Medical condition: Open-angle Glaucoma and Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    20.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    20.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) DE (Completed) DK (Completed) PL (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2013-002947-27 Sponsor Protocol Number: SYL040012_IV Start Date*: 2014-07-01
    Sponsor Name:Sylentis S.A.U.
    Full Title: A phase II, observer masked, active controlled study of SYL040012 for the treatment of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension (SYLTAG)
    Medical condition: Open angle glaucoma - intraocular pressure
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004848 10022801 Intraocular pressure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: EE (Completed) DE (Completed) ES (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
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