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Clinical trials for Regression

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    452 result(s) found for: Regression. Displaying page 1 of 23.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2018-003426-89 Sponsor Protocol Number: E2020-J081-345 Start Date*: 2018-10-18
    Sponsor Name:Eisai Co., Ltd. (Japan)
    Full Title: A Double-blind, Placebo-controlled Comparative Study and Open-label Extension Study to Confirm the Efficacy and Safety of E2020 in Subjects With Down Syndrome Having Regression Symptoms and Disable...
    Medical condition: Down syndrome, regression symptoms and disabled activities of daily living
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2012-001340-21 Sponsor Protocol Number: KB046 Start Date*: 2013-01-15
    Sponsor Name:KEDRION
    Full Title: A Historically-Controlled Phase II/III study to Evaluate Efficacy and Safety of Kedrion Human Plasminogen Eye Drop Preparation in Patients Diagnosed with Ligneous Conjunctivitis
    Medical condition: Ligneous Conjunctivitis ( MedDRA Code vers. 15.0: 10071570 LLT - no present in OsSC database) associated with Type I Plasminogen Deficiency
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2013-002825-52 Sponsor Protocol Number: CRAD001A2401T Start Date*: 2014-04-03
    Sponsor Name:Medizinische Hochschule Hannover
    Full Title: Single-center, open-label, single-arm Phase IIa study in kidney transplant patients with acute T-cell-mediated rejection in renal transplant according to Banff criteria (class IA and IB) without (s...
    Medical condition: Acute cellular rejection after kidney transplantation
    Disease: Version SOC Term Classification Code Term Level
    16.1 10021428 - Immune system disorders 10023439 Kidney transplant rejection PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2013-005559-34 Sponsor Protocol Number: AIO-PAK-0313 Start Date*: 2015-01-19
    Sponsor Name:AIO-Studien-gGmbH
    Full Title: Neoadjuvant plus adjuvant or only adjuvant nab-Paclitaxel plus Gemcitabine for resectable pancreatic cancer - The AIO-NEONAX trial (AIO-PAK-0313) A prospective, randomized, controlled, phase II st...
    Medical condition: Resectable pancreatic cancer
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004864 10033608 Pancreatic cancer resectable LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-003778-17 Sponsor Protocol Number: CHL.1/02-2014 Start Date*: 2015-02-23
    Sponsor Name:Sintetica S.A.
    Full Title: Spinal anaesthesia with Chloroprocaine HCl 1% for elective lower limb procedures of short duration: a prospective, randomised, observer-blind study in adult patients
    Medical condition: Short duration (less than 40 min) lower limb surgery via spinal anaesthesia
    Disease: Version SOC Term Classification Code Term Level
    17.1 10042613 - Surgical and medical procedures 10041536 Spinal anaesthesia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2013-001856-36 Sponsor Protocol Number: MEDICARE Start Date*: 2013-08-05
    Sponsor Name:CHU DE POITIERS
    Full Title: Efficacy and safety of Aflibercept (Eylea®) in proliferative diabetic retinopathy
    Medical condition: Percentage of patients showing regression of retinal neovascularization between baseline and month 12 in the Aflibercept group versus laser group
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004853 10036857 Proliferative diabetic retinopathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-012194-35 Sponsor Protocol Number: 290404BS Start Date*: 2009-12-22
    Sponsor Name:bioskin GmbH
    Full Title: A single-center, randomized, controlled, observer-blind, phase IV study to develop the atopic localized eczema regression test (ALERT) using marketed topical corticosteroid formulations of differen...
    Medical condition: Patients with a pre-disposition for Atopic Dermatitis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-001368-20 Sponsor Protocol Number: ECR-AMD-2015-09 Start Date*: 2015-09-01
    Sponsor Name:AIBILI - Association for Innovation and Biomedical Research ob Light and Image
    Full Title: A Randomized, Double-masked, Sham-controlled Phase 4 Study of the Efficacy, Safety, and Tolerability of Intravitreal Aflibercept Monotherapy Compared to Aflibercept With Adjunctive Photodynamic The...
    Medical condition: Polypoidal Choroidal Vasculopathy
    Disease: Version SOC Term Classification Code Term Level
    20.1 10015919 - Eye disorders 10063381 Polypoidal choroidal vasculopathy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PT (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2022-002443-21 Sponsor Protocol Number: CO44195 Start Date*: 2023-03-01
    Sponsor Name:F. HOFFMANN - LA ROCHE LTD.
    Full Title: A PHASE II, SINGLE-ARM STUDY OF GIREDESTRANT IN PATIENTS WITH GRADE 1 ENDOMETRIAL CANCER
    Medical condition: Grade 1 Endometrial Cancer
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10014738 Endometrial cancer stage I PT
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10014733 Endometrial cancer PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-001770-30 Sponsor Protocol Number: 2020COVID-19TCZ Start Date*: 2020-04-21
    Sponsor Name:CHU AMBROISE PARE
    Full Title: COVID 19: Experimental use of tocilizumab (Roactemra®) in severe SARS-CoV-2 related pneumonia.
    Medical condition: viral pneumonia caused by the new coronavirus (SARS-CoV-2)
    Disease: Version SOC Term Classification Code Term Level
    21.1 10021881 - Infections and infestations 10035737 Pneumonia viral PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-002365-13 Sponsor Protocol Number: IMP 12791 Start Date*: 2007-06-29
    Sponsor Name:Bayer B.V.
    Full Title: Sorafenib as adjuvant to radioiodine therapy in non-medullary thyroid carcinoma
    Medical condition: non-medullary thyroid carcinoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2012-001612-34 Sponsor Protocol Number: GESIDA-7412 Start Date*: 2013-02-18
    Sponsor Name:Fundación SEIMC-GESIDA
    Full Title: A prostective, with one site, open-label not controled trial, for the observation of treatment with CIDOFOVIR 1%, 3 nights per week, during 4 weeks, of Anal Intraephitelial Neoplasia, high level, i...
    Medical condition: Intraephitelial Anal Neoplasia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2014-004473-16 Sponsor Protocol Number: SL001-2.0 Start Date*: 2016-07-19
    Sponsor Name:Masarykův onkologický ústav
    Full Title: Prospective study investigating efficacy of lanreotide on decrease of chemotherapy induced diarrhoea (CID) in patiens with colorectal carcinoma.
    Medical condition: Chemotherapy induced diarrhoea that is resistant to common treatment including loperamide in patients with colorectal carcinoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-000427-41 Sponsor Protocol Number: CPPFAP-310 Start Date*: 2014-05-15
    Sponsor Name:Cancer Prevention Pharmaceuticals, Inc.
    Full Title: A Double-Blind, Randomized, Phase III Trial of the Safety and Efficacy of CPP-1X/Sulindac Compared With CPP-1X, Sulindac as Single Agents in Patients with Familial Adenomatous Polyposis (FAP)
    Medical condition: Familial Adenomatous Polyposis (FAP)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) NL (Completed) ES (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2022-003381-21 Sponsor Protocol Number: RAFAEL Start Date*: 2023-09-11
    Sponsor Name:Psyon, s.r.o.
    Full Title: Regression of atherosclerosis induced by life changing experience with psilocybin
    Medical condition: Ischemic Heart Disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-002539-13 Sponsor Protocol Number: CARE-ROP Start Date*: 2014-04-01
    Sponsor Name:University Medical Center Freiburg
    Full Title: Multicenter randomized double masked parallel design exploratory study to assess safety and efficacy of two different doses of intravitreal anti-VEGF treatment with ranibizumab (0.12 mg vs. 0.20 mg...
    Medical condition: retinopathy of prematurity
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004853 10038974 Retrolental fibroplasia LLT
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-000856-34 Sponsor Protocol Number: CSPP100A2316 Start Date*: 2005-08-26
    Sponsor Name:Novartis Farmacéutica S.A.
    Full Title: A 36 week, randomized, double-blind, multi-center, parallel group study comparing the efficacy and safety of aliskiren in combination with losartan compared to losartan on the regression of left ve...
    Medical condition: left ventricular hypertrophy in overweight patients with essential hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) FI (Completed) DE (Completed) SE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2016-002761-63 Sponsor Protocol Number: HPV-301 Start Date*: 2018-04-16
    Sponsor Name:Inovio Pharmaceuticals, Inc.
    Full Title: A PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PHASE 3 STUDY OF VGX-3100 DELIVERED INTRAMUSCULARLY FOLLOWED BY ELECTROPORATION WITH CELLECTRA™ 5PSP FOR THE TREATMENT OF HPV-16 AND/OR H...
    Medical condition: HPV-16 AND/OR HPV-18 RELATED HIGH GRADE SQUAMOUS INTRAEPITHELIAL LESIONS (HSIL) OF THE CERVIX
    Disease: Version SOC Term Classification Code Term Level
    21.1 10022891 - Investigations 10064328 Human papilloma virus test positive PT
    21.1 100000004872 10066237 Cervical high grade squamous intraepithelial lesion LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA) LT (Completed) FI (Completed) DE (Completed) CZ (Prematurely Ended) ES (Completed) PT (Completed) PL (Completed) SK (Completed) BE (Completed) NL (Ongoing) EE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-019884-12 Sponsor Protocol Number: INFIRE-001 Start Date*: 2010-12-17
    Sponsor Name:Universitätsklinikum Aachen
    Full Title: Induction of Fibrosis Regression regarding Chronic Hepatitis B Infection
    Medical condition: Patients with chronic hepatitis B infection and a relevant grade of fibrosis (histological >= F2)
    Disease: Version SOC Term Classification Code Term Level
    15.0 10021881 - Infections and infestations 10008910 Chronic hepatitis B LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-005663-31 Sponsor Protocol Number: 12020 Start Date*: 2022-10-04
    Sponsor Name:AZIENDA OSPEDALIERA ORDINE MAURIZIANO DI TORINO
    Full Title: CARotid plaqUe StabilizatiOn and regression with evolocumab)
    Medical condition: atherosclerosis desead
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10007541 Cardiac disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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