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Clinical trials for Sepsis

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
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    The EU Clinical Trials Register currently displays   43871   clinical trials with a EudraCT protocol, of which   7290   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    483 result(s) found for: Sepsis. Displaying page 1 of 25.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2009-011346-26 Sponsor Protocol Number: MAB-N007 Start Date*: 2009-11-27
    Sponsor Name:Biosynexus Incorporated
    Full Title: Ensayo de fase 2b/3, multicéntrico, aleatorizado, doble ciego, controlado con placebo, para evaluar la seguridad y eficacia de Pagibaximab Inyectable en recién nacidos con peso de nacimiento muy ba...
    Medical condition: Prevención de la septicemia causada por estafilococos en recién nacidos con peso de nacimiento muy bajo.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10040049 Sepsis neonatal LLT
    12.0 10056430 Staphylococcal sepsis LLT
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: ES (Completed) GB (Completed) DE (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-005902-30 Sponsor Protocol Number: FAR01-2011 Start Date*: 2012-02-13
    Sponsor Name:Servicio de Farmacia. Hospital Universitari de Bellvitge
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10040047 Sepsis PT
    14.1 10021881 - Infections and infestations 10053840 Bacterial sepsis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-001100-38 Sponsor Protocol Number: FARM97AJNN Start Date*: 2014-07-09
    Sponsor Name:DIPART. DI NEUROSCIENZE, SCIENZE RIPRODUTTIVE E ODONTOSTOMATOLOGICHE DELL’UNIVERSITà DEGLI STUDI DI NAPOLI “FEDERICO II"
    Full Title: Antagonists of Angiotensin II Receptors in sepsis
    Medical condition: SEPSIS
    Disease: Version SOC Term Classification Code Term Level
    16.1 10021881 - Infections and infestations 10040047 Sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-002788-28 Sponsor Protocol Number: RHM CHI434 Start Date*: 2008-01-15
    Sponsor Name:Southampton University Hospital NHS Trust
    Full Title: Evaluation of Corticosteroid therapy in Childhood Severe Sepsis (Steroids in Paediatric Sepsis, StePS) - a randomised pilot study
    Medical condition: Children with severe sepsis requiring mechanical ventilation presenting within 12 hours of onset. The majority of children will either have community acquired sepsis (most commonly meningococcal or...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10040047 Sepsis LLT
    9.1 10053840 Bacterial sepsis LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-001056-55 Sponsor Protocol Number: INCLASS Start Date*: 2017-08-28
    Sponsor Name:HELLENIC INSTITUTE FOR THE STUDY OF SEPSIS
    Full Title: A DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED CLINICAL STUDY OF THE EFFICACY OF INTRAVENOUS CLARITHROMYCIN AS ADJUNCTIVE TREATMENT IN PATIENTS WITH SEPSIS AND RESPIRATORY AND MULTIPLE ORGAN DYSFUN...
    Medical condition: IMMUNE MODULATION WITH CLARITHROMYCIN IN SEPSIS WITH MULTIPLE ORGAN AND RESPIRATORY DYSFUNCTION
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10040047 Sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Ongoing) BE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-019345-26 Sponsor Protocol Number: 03-AnIt-10 Start Date*: 2010-06-02
    Sponsor Name:Department of Anesthesiology and Intensive Care, University Hospital Muenster
    Full Title: Immunmodulatory effects of local anesthetics on neutrophils during sepsis
    Medical condition: Sepsis and severe sepsis
    Disease: Version SOC Term Classification Code Term Level
    12.1 10040047 Sepsis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006984-21 Sponsor Protocol Number: MAXSEP Start Date*: 2007-05-29
    Sponsor Name:Friedrich-Schiller-University of Jena
    Full Title: prospective, randomized, open, multicentre trial to assess the influence of empiric antibiotic monotherapy with meropenem (Meronem) versus combination with moxifloxacin (Avalox) on the organ functi...
    Medical condition: severe sepsis / septic shock
    Disease: Version SOC Term Classification Code Term Level
    9.1 10040047 Sepsis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-005768-74 Sponsor Protocol Number: ImmunoSep Start Date*: 2021-02-18
    Sponsor Name:Hellenic Institute for the Study of Sepsis
    Full Title: PERSONALIZED IMMUNOTHERAPY IN SEPSIS: A MULTICENTRE AND MULTINATIONAL, DOUBLE-BLIND, DOUBLE-DUMMY RANDOMIZED CLINICAL TRIAL (THE IMMUNOSEP TRIAL)
    Medical condition: Sepsis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10040053 Sepsis secondary LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Ongoing) NL (Ongoing) IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-015168-32 Sponsor Protocol Number: D0620C00003 Start Date*: 2010-10-04
    Sponsor Name:AstraZeneca AB
    Full Title: A Multicentre, Randomised, Double Blind, Placebo controlled Phase IIb Study to compare the Efficacy and Safety of Two Dosing Regimens of Intravenous Infusions of CytoFab™ (AZD9773) in Adult Patient...
    Medical condition: Severe sepsis and/or septic shock
    Disease: Version SOC Term Classification Code Term Level
    12.1 10040047 Sepsis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) FR (Completed) ES (Completed) CZ (Completed) FI (Completed)
    Trial results: View results
    EudraCT Number: 2018-000488-98 Sponsor Protocol Number: PPI-SepsisTrial Start Date*: 2018-07-12
    Sponsor Name:OSPEDALE SAN RAFFAELE
    Full Title: Proton pump inhibitors (PPI) as a new strategy for therapy in sepsis: clinical trial to reduce severity of organ failure and in vitro experiments to search specific hallmarks in monocytes from sept...
    Medical condition: Sepsis is a severe disease with a high mortality rate and lack of efficacious therapies
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10040047 Sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-002555-26 Sponsor Protocol Number: RH-RBWH-2014-1 Start Date*: 2014-07-25
    Sponsor Name:Dept. of Intensive Care Medicine, Copenhagen University Hospital, Rigshospitalet
    Full Title: MEROPENEM and CIPROFLOXACIN DOSING IN THE CRITICALLY ILL PATIENT WITH SEPTIC SHOCK – A SINGLE CENTER PHARMACOKINETIC STUDY
    Medical condition: Septic Shock
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004862 10040050 Sepsis NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2007-004333-42 Sponsor Protocol Number: SISPCT Start Date*: Information not available in EudraCT
    Sponsor Name:Friedrich-Schiller-University of Jena
    Full Title: Prospective randomized clinical multicenter trial about the effect of an adjunctive intravenous treatment with sodium selenite (selenase®T, double-blind) and a procalcitonin guided causal therapy (...
    Medical condition: severe sepsis / septic shock
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10040047 Sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-004834-32 Sponsor Protocol Number: PROTEINA-C Start Date*: 2012-06-08
    Sponsor Name:FONDAZIONE CENTRO S. RAFFAELE DEL MONTE TABOR
    Full Title: Administration of concentrated Protein C in patients with severe sepsis and contraindications to activated protein C. A monocentric, randomised placebo-controlled study.
    Medical condition: patients affected by severe sepsis admitted to intensive care
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10040047 Sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-002171-26 Sponsor Protocol Number: PROVIDE Start Date*: 2017-10-20
    Sponsor Name:Hellenic Institute for the Study of Sepsis
    Full Title: A PERSONALIZED RANDOMIZED TRIAL OF VALIdATION AND RESTORATION OF IMMUNE DYSFUNCTION IN SEVERE INFECTIONS AND SEPSIS: THE PROVIDE TRIAL
    Medical condition: A TRIAL FOR IMMUNOMODULATION IN SEPSIS
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10040047 Sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-000902-37 Sponsor Protocol Number: RH-ITA-005 Start Date*: 2014-06-27
    Sponsor Name:Dept. of Intensive Care, Copenhagen University Hospital, Rigshospitalet
    Full Title: Conservative vs. Liberal Approach to fluid therapy of Septic Shock in Intensive Care
    Medical condition: Septic shock
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004862 10040050 Sepsis NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2005-003561-16 Sponsor Protocol Number: TAK-242/01-04-TL-242-011 Start Date*: 2005-12-21
    Sponsor Name:Takeda Europe R&D Centre Ltd
    Full Title: A Pivotal, Multicentre, Multinational, Randomised, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of TAK-242 in Adults with Severe Sepsis
    Medical condition: Severe sepsis
    Disease: Version SOC Term Classification Code Term Level
    8 10040047 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) BE (Completed) FI (Prematurely Ended) AT (Prematurely Ended) CZ (Prematurely Ended) SE (Prematurely Ended) ES (Completed) PT (Prematurely Ended) DK (Prematurely Ended) IT (Prematurely Ended) DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-007989-34 Sponsor Protocol Number: PENTA-CIRRO Start Date*: 2009-09-09
    Sponsor Name:AZIENDA OSPEDALIERA POLICLINICO DI MODENA
    Full Title: Use of policlonal immunoglobulins (Pentaglobin) in the treatment of sepsis in cirrhotic patients awaiting for liver transplantation.
    Medical condition: Sepsis in cirrhotic patients.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019641 PT
    9.1 10053840 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-002236-17 Sponsor Protocol Number: VACIRISS Start Date*: 2018-04-16
    Sponsor Name:Guy's and St Thomas' NHS Foundation Trust
    Full Title: Pneumococcal Vaccination to Accelerate Immune Recovery in Sepsis Survivors: randomized placebo-controlled trial
    Medical condition: Sepsis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10040047 Sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2015-000629-35 Sponsor Protocol Number: version1.1.11/03/2015 Start Date*: 2015-08-10
    Sponsor Name:Plymouth Hospitals NHS Trust
    Full Title: (Feasibility) Open label Randomised Controlled Trial of Hyperoxic O2 Therapy vs. Normoxic O2 Therapy in Sepsis
    Medical condition: sepsis
    Disease: Version SOC Term Classification Code Term Level
    18.0 10021881 - Infections and infestations 10040047 Sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2021-002300-12 Sponsor Protocol Number: EPOS_ZKSJ0134 Start Date*: 2021-12-20
    Sponsor Name:Friedrich Schiller University
    Full Title: Epirubicin for the Treatment of Sepsis & Septic Shock
    Medical condition: Adult (≥ 18 years) patients admitted to the ICU or IMC with sepsis or septic shock, diagnosed within the previous 24 hours.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10040047 Sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
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