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Clinical trials for Sepsis Six

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    24 result(s) found for: Sepsis Six. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2017-002011-33 Sponsor Protocol Number: PROGRESS Start Date*: 2017-08-28
    Sponsor Name:Hellenic Institute for the Study of Sepsis
    Full Title: A RANDOMIZED PROSPECTIVE CLINICAL TRIAL TO ASSESS THE ROLE OF PROCALCITONIN-GUIDED ANTIMICROBIAL THERAPY TO REDUCE LONG-TERM INFECTIONS SEQUELAE
    Medical condition: USE OF PROCALCITONIN IN EARLY STOP OF ANTIBIOTICS TO AVOID LONG-TERM CONSEQUENCES
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10040047 Sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: View results
    EudraCT Number: 2015-003528-29 Sponsor Protocol Number: CCHI621ADE04 Start Date*: 2016-04-14
    Sponsor Name:Novartis Pharma GmbH
    Full Title: A Multicenter, Open-label, Randomized, Two Arm Study to Investigate the Efficacy and Safety of a Therapy Avoiding Intraoperative Steroids in Combination With Basiliximab, Cyclosporine/Cyclosporine ...
    Medical condition: Liver Transplantation Infection
    Disease: Version SOC Term Classification Code Term Level
    19.0 10021881 - Infections and infestations 10077116 Systemic infection PT
    19.0 100000004865 10024716 Liver transplantation LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2020-001862-12 Sponsor Protocol Number: s63213 Start Date*: 2021-03-23
    Sponsor Name:University Hospitals Leuven, Clinical Trial Centre
    Full Title: Early administration of Vitamin C in patients with sepsis or septic shock in emergency departments: a multicentre, double blinded, randomized controlled trial: the C-EASIE trial.
    Medical condition: We will investigate the potential benefit of early administration of high doses of Vitamin C in addition to standard care in patients with sepsis or septic shock.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10040047 Sepsis PT
    23.1 10021881 - Infections and infestations 10040070 Septic shock PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-001037-40 Sponsor Protocol Number: IFX-1-P2.1 Start Date*: 2014-02-11
    Sponsor Name:InflaRx GmbH
    Full Title: A phase II randomized, placebo-controlled, double-blind, dose controlled trial in patients suffering from early, newly developing abdominal or pulmonary derived septic organ dysfunction to evaluate...
    Medical condition: septic organ dysfunction
    Disease: Version SOC Term Classification Code Term Level
    18.1 10021881 - Infections and infestations 10040047 Sepsis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2013-001549-15 Sponsor Protocol Number: C0921004 Start Date*: 2013-09-19
    Sponsor Name:Pfizer Inc (235 East 42nd Street, New York, New York 10017)
    Full Title: The long-term antibody persistence of MenACWY-TT vaccine (PF-06866681) versus Meningitec® or Mencevax® ACWY in healthy adolescents and adults and a booster dose of MenACWY-TT administered 10 years ...
    Medical condition: Meningococcal disease
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004862 10028910 Neisseria meningitides meningitis LLT
    18.1 100000004862 10028912 Neisseria meningitis sepsis LLT
    18.1 100000004862 10027276 Meningococcal meningitis LLT
    18.1 100000004862 10058885 Meningococcal bacteremia LLT
    18.1 100000004862 10027275 Meningococcal infection, unspecified LLT
    18.1 100000004862 10040048 Sepsis meningococcal LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2015-000872-89 Sponsor Protocol Number: MK001 Start Date*: 2015-10-29
    Sponsor Name:University of Oxford
    Full Title: ANODE: a randomised controlled trial of prophylactic ANtibiotics to investigate the prevention of infection following Operative vaginal DElivery.
    Medical condition: Maternal infection in the first six weeks after operative vaginal delivery.
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2021-002290-25 Sponsor Protocol Number: FEBATRIC Start Date*: 2022-02-10
    Sponsor Name:Nadační fond Donatio intensivistam
    Full Title: Faecal bacteriotherapy for postantibiotic diarrhoea in critically ill patients
    Medical condition: Postantibiotic diarrhoea
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2021-000627-12 Sponsor Protocol Number: CV43140 Start Date*: 2021-06-01
    Sponsor Name:F. Hoffmann La Roche Ltd.
    Full Title: A MULTICENTER, OBSERVATIONAL, 6 MONTH FOLLOW-UP STUDY OF PATIENTS WITH COVID 19 PREVIOUSLY ENROLLED IN A RO7496998 (AT-527) STUDY
    Medical condition: Coronavirus disease 2019 (COVID-19)
    Disease: Version SOC Term Classification Code Term Level
    23.1 100000004862 10084401 COVID-19 respiratory infection LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: BE (Completed) PT (Prematurely Ended) DK (Completed) DE (Completed) IT (Prematurely Ended) RO (Completed)
    Trial results: View results
    EudraCT Number: 2019-004118-33 Sponsor Protocol Number: PATCH_Trauma Start Date*: 2020-11-03
    Sponsor Name:Universität Witten/Herdecke
    Full Title: A multi-centre randomised, double-blind, placebo-controlled trial of pre-hospital treatment with tranexamic acid for severely injured patients at risk of acute traumatic coagulopathy.
    Medical condition: Trauma patients with risk for acute traumatic Coagulopathy and Hemorrhage
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10044528 Traumatic injury LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-000658-22 Sponsor Protocol Number: PROT 1203 Start Date*: 2005-06-16
    Sponsor Name:University of Oxford, NDM
    Full Title: The Second Multi-Centre Intra-Pleural Sepsis Trial (MIST2), to assess whether DNase or Alteplase improves pleural fluid drainage in pleural infection.
    Medical condition: Empyema and complicated parapneumonic pleural effusion.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-006225-27 Sponsor Protocol Number: SP000283 Start Date*: 2008-12-15
    Sponsor Name:The University of Liverpool [...]
    1. The University of Liverpool
    2. Aintree University Hospital NHS Trust
    Full Title: Hyperbaric Oxygen to Prevent Osteoradionecrosis of the Irradiated Mandible (HOPON)
    Medical condition: Osteoradionecrosis (ORN) of the irradiated mandible; the most feared complication of radiotherapy for head and neck cancer.
    Disease: Version SOC Term Classification Code Term Level
    19.1 10028395 - Musculoskeletal and connective tissue disorders 10064658 Osteonecrosis of jaw PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-005159-18 Sponsor Protocol Number: CRO2047 Start Date*: 2013-08-28
    Sponsor Name:Imperial College, London
    Full Title: An efficacy and mechanism evaluation study of Levosimendan for the Prevention of Acute oRgan Dysfunction in Sepsis (LeoPARDS)
    Medical condition: Septic shock.
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004867 10028237 Multiple organ failure LLT
    16.0 10021881 - Infections and infestations 10040070 Septic shock PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2020-000140-58 Sponsor Protocol Number: NL7255100000 Start Date*: 2020-07-23
    Sponsor Name:Leiden University Medical Center
    Full Title: Complement Inhibition: Attacking the Overshooting Inflammation @fter Traumatic Brain Injury - A phase II trial on the safety and efficacy of C1 esterase inhibitor Cinryze for the acute management o...
    Medical condition: Severe traumatic Brain Injury (TBI) with GCS < 13
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10060690 Traumatic brain injury LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2008-000140-13 Sponsor Protocol Number: FPCLI001 Start Date*: 2008-05-09
    Sponsor Name:Faron Pharmaceuticals Limited
    Full Title: A Phase I/II Open–Label study to Assess the Safety, Tolerability and Preliminary Efficacy of FP-1201 (Recombinant Human Interferon Beta) in the treatment of patients with Acute Lung Injury and Acut...
    Medical condition: Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-001012-32 Sponsor Protocol Number: GPI-04-0001 Start Date*: 2005-03-31
    Sponsor Name:Gloucester Pharmaceuticals Inc.
    Full Title: A single agent Phase II study of depsipeptide (FK228) in the treatment of Cutaneous T-cell lymphoma
    Medical condition: Cutaneous T-cell lymphoma (CTCL), (peripheral T-cell lymphoma unspecified NOS)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2012-003192-19 Sponsor Protocol Number: ISRCTN11225767 Start Date*: 2013-02-22
    Sponsor Name:London School Of Hygiene and Tropical Medicine
    Full Title: Tranexamic acid for the treatment of gastrointestinal haemorrhage: an international randomised, double blind placebo controlled trial
    Medical condition: Gastrointestinal hemorrhage
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004856 10017960 Gastrointestinal hemorrhage LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) RO (Completed) ES (Prematurely Ended) IE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-004301-41 Sponsor Protocol Number: P170404J Start Date*: 2018-10-15
    Sponsor Name:ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS [...]
    1. ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS
    2. Assistance Publique-Hopitaux de Paris(AP-HP)
    Full Title: FURosemide Stress Test to predict need of Renal Replacement THERapy in Ischemic Acute Tubular Necrosis in Intensive Care Units
    Medical condition: FURosemide Stress Test to predict need of Renal Replacement THERapy in Ischemic Acute Tubular Necrosis in Intensive Care Units
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004857 10001099 Acute tubular necrosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-002943-92 Sponsor Protocol Number: FLR115332 Start Date*: 2011-11-07
    Sponsor Name:GlaxoSmithKline Research and Development Limited
    Full Title: A Single-arm, Open Label Study Evaluating the Impact on Lifestyle of a New Thermo Stable Formulation of FLOLAN™ in Subjects with Pulmonary Arterial Hypertension (PAH)
    Medical condition: pulmonary arterial hypertension (PAH)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10064911 Pulmonary arterial hypertension PT
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10065150 Associated with pulmonary arterial hypertension LLT
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10065152 Familial pulmonary arterial hypertension LLT
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10065151 Idiopathic pulmonary arterial hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-003764-45 Sponsor Protocol Number: UOL0727 Start Date*: 2020-02-14
    Sponsor Name:University of Leicester
    Full Title: Multicentre, open-label, randomised controlled trial of early surfactant therapy versus expectant management in late preterm and early term infants with respiratory distress.
    Medical condition: Respiratory distress in neonates born at 34 to 38+6 weeks of gestation
    Disease:
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2020-005731-67 Sponsor Protocol Number: NLxxxxxxxxxx Start Date*: 2021-07-02
    Sponsor Name:Haaglanden Medisch Centrum
    Full Title: Complement Inhibition: Attacking the Overshooting Inflammation @fter Subarachnoid Hemorrhage - A phase II trial on the safety and efficacy of C1 esterase inhibitor for the acute management of subar...
    Medical condition: Subarachnoid hemorrhage
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004852 10042320 Subarachnoid hemorrhage LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
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