- Trials with a EudraCT protocol (33)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (0)
33 result(s) found for: Trifluridine.
Displaying page 1 of 2.
EudraCT Number: 2021-003151-41 | Sponsor Protocol Number: CL3-95026-001 | Start Date*: 2022-01-25 | |||||||||||
Sponsor Name:Institut de Recherches Internationales Servier | |||||||||||||
Full Title: A randomised, open-label, multi-centre, two-arm Phase 3 study comparing futuximab/modotuximab in combination with trifluridine/tipiracil to trifluridine/tipiracil single agent with a Safety Lead-In... | |||||||||||||
Medical condition: Metastatic colorectal cancer | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DK (Prematurely Ended) BE (Completed) FI (Completed) HU (Completed) PL (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2020-001976-14 | Sponsor Protocol Number: CL3-95005-007 | Start Date*: 2020-09-22 | |||||||||||
Sponsor Name:Institut de Recherches Internationales Servier | |||||||||||||
Full Title: An open-label, randomised, phase III study comparing trifluridine/tipiracil in combination with bevacizumab to trifluridine/tipiracil monotherapy in patients with refractory metastatic colorectal c... | |||||||||||||
Medical condition: Refractory metastatic colorectal cancer | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DK (Ongoing) FR (Completed) DE (Completed) HU (Completed) BE (Completed) AT (Completed) IT (Ongoing) | |||||||||||||
Trial results: View results |
EudraCT Number: 2021-003799-15 | Sponsor Protocol Number: ACE1100-01 | Start Date*: 2022-04-25 | |||||||||||
Sponsor Name:Ascelia Pharma AB | |||||||||||||
Full Title: A Randomized, Double-blind Study to Investigate the Safety, Pharmacokinetics, and Antitumor Activity of ASC-201 Plus Trifluridine/Tipiracil Compared With Trifluridine/Tipiracil in Patients With Adv... | |||||||||||||
Medical condition: Advanced Gastric Cancer. | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: ES (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2018-001600-12 | Sponsor Protocol Number: 20177097 | Start Date*: 2019-05-29 | |||||||||||
Sponsor Name:Dipartimento di Medicina di Precisione - Università degli studi della Campania "L. Vanvitelli" | |||||||||||||
Full Title: Phase II randomized study evaluating the efficacy of panitumumab (VEctibix) and Trifluridine-Tipiracil (LOnsurf) in pretreated RAS wild type metastatic colorectal cancer patients: the VELO trial | |||||||||||||
Medical condition: mCRC | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2019-004223-20 | Sponsor Protocol Number: FIRE-8 | Start Date*: 2021-06-15 | |||||||||||
Sponsor Name:Charité Universitätsmedizin Berlin | |||||||||||||
Full Title: Prospective, randomized, open, multicenter Phase II trial to investigate the efficacy of trifluridine/tipiracil plus panitumumab versus trifluridine/tipiracil plus bevacizumab as first-line treatme... | |||||||||||||
Medical condition: Prospective, randomized, open, multicenter Phase II trial to investigate the efficacy of trifluridine/tipiracil plus panitumumab versus trifluridine/tipiracil plus bevacizumab as first-line treatme... | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2016-002311-18 | Sponsor Protocol Number: CL3-95005-004 | Start Date*: 2016-09-19 | |||||||||||
Sponsor Name:Laboratorios Servier S. L. | |||||||||||||
Full Title: An open-label early access phase IIIb study of trifluridine / tipiracil (S 95005/TAS-102) in patients with a pretreated metastatic colorectal cancer. | |||||||||||||
Medical condition: Metastatic colorectal cancer | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: ES (Prematurely Ended) BE (Completed) PT (Completed) PL (Completed) SI (Completed) FR (Completed) SK (Completed) BG (Completed) HR (Completed) IT (Completed) RO (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2021-004008-16 | Sponsor Protocol Number: 20190172 | Start Date*: 2022-01-26 | |||||||||||
Sponsor Name:Amgen, Inc. | |||||||||||||
Full Title: A Phase 3 Multicenter, Randomized, Open-label, Active-controlled Study of Sotorasib and Panitumumab Versus Investigator’s Choice (Trifluridine and Tipiracil, or Regorafenib) for the Treatment of Pr... | |||||||||||||
Medical condition: Previously Treated Metastatic Colorectal Cancer Subjects with KRAS p.G12C Mutation | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: FR (Ongoing) DE (Restarted) GR (Ongoing) ES (Ongoing) IT (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2017-004059-22 | Sponsor Protocol Number: CL3-95005-006 | Start Date*: 2018-06-01 | |||||||||||
Sponsor Name:Institut de Recherches Internationales Servier | |||||||||||||
Full Title: An open-label, randomised, phase III Study cOmparing trifLuridine/tipiracil (S 95005) in combination with bevacizumab to capecitabine in combination with bevacizumab in firST-line treatment of pati... | |||||||||||||
Medical condition: Metastatic colorectal cancer | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) IE (Completed) SE (Ongoing) AT (Completed) ES (Ongoing) DK (Ongoing) LT (Ongoing) NL (Completed) LV (Ongoing) SK (Ongoing) CZ (Ongoing) HU (Completed) DE (Completed) PL (Ongoing) PT (Completed) BG (Completed) IT (Ongoing) RO (Ongoing) | |||||||||||||
Trial results: View results |
EudraCT Number: 2018-000627-13 | Sponsor Protocol Number: C201 | Start Date*: 2018-06-06 | ||||||||||||||||||||||||||
Sponsor Name:GAMAMABS Pharma | ||||||||||||||||||||||||||||
Full Title: OPEN, NON CONTROLLED, PARALLEL COHORTS, MULTICENTER, PHASE 2A STUDY FOR THE EVALUATION OF THE ANTITUMOR ACTIVITY OF GM102 SINGLE AGENT AND IN COMBINATION WITH CHEMOTHERAPY IN PATIENTS WITH LOCALLY ... | ||||||||||||||||||||||||||||
Medical condition: Patients with locally advanced or metastatic colorectal cancer (CRC), having received at least two lines of therapy for the locally advanced or metastatic CRC disease. | ||||||||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||||||||||||
Trial protocol: CZ (Completed) BE (Completed) | ||||||||||||||||||||||||||||
Trial results: View results |
EudraCT Number: 2020-000923-37 | Sponsor Protocol Number: TriComB | Start Date*: 2021-08-04 | |||||||||||
Sponsor Name:G.O.N.O. - GRUPPO ONCOLOGICO DEL NORD OVEST | |||||||||||||
Full Title: A phase 1/2 study exploring the safety and activity of Trifluridine/tipiracil in combination with capecitabine and bevacizumab in metastatic colorectal cancer patients. | |||||||||||||
Medical condition: metastatic colorectal cancer | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2019-004196-39 | Sponsor Protocol Number: UC-GIG-1910 | Start Date*: 2020-07-23 | |||||||||||
Sponsor Name:UNICANCER | |||||||||||||
Full Title: A randomized, phase II study comparing the sequences of regorafenib and trifluridine/tipiracil, after failure of standard therapies in patients with metastatic colorectal cancer | |||||||||||||
Medical condition: The study population will consist of male and female patients aged ≥ 18 years old with metastatic colorectal cancer after failure of fluoropyrimidine-, irinotecan-, and oxaliplatin-based chemothera... | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: FR (Ongoing) BE (Ongoing) IT (Prematurely Ended) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2018-004845-18 | Sponsor Protocol Number: 1.4 | Start Date*: 2019-03-27 |
Sponsor Name:Lene Bæksgaard Jensen | ||
Full Title: LON-GAS TRIFLURIDINE/TIPIRACIL (FTD/TPI) with or without Bevacizumab in patients with platinum-refractory esophago-gastric adenocarcinoma. A randomized phase III study | ||
Medical condition: TRIFLURIDINE/TIPIRACIL (FTD/TPI) with or without bevacizumab in patients with platinum-refractory esophago-gastric adenocarcinoma | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: DK (Completed) | ||
Trial results: (No results available) |
EudraCT Number: 2021-004285-35 | Sponsor Protocol Number: CA224-123 | Start Date*: 2022-06-27 | ||||||||||||||||
Sponsor Name:Bristol-Myers Squibb International Corporation | ||||||||||||||||||
Full Title: A Phase 3, Randomized, Open-label Study of Relatlimab-nivolumab Fixed-dose Combination Versus Regorafenib or Trifluridine + Tipiracil (TAS-102) for Participants with Later-lines of Metastatic Color... | ||||||||||||||||||
Medical condition: Metastatic Colorectal Cancer | ||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: AT (Trial now transitioned) ES (Ongoing) DE (Trial now transitioned) IT (Ongoing) PL (Trial now transitioned) NL (Trial now transitioned) CZ (Trial now transitioned) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2020-004636-25 | Sponsor Protocol Number: ACOTAS_G098 | Start Date*: 2021-06-17 | ||||||||||||||||
Sponsor Name:GERCOR | ||||||||||||||||||
Full Title: A phase II study to evaluate the rate of cardiovascular events during trifluridine/tipiracil +/-oxaliplatin treatment in colorectal/oesogastric adenocarcinoma patients that have experienced a pas... | ||||||||||||||||||
Medical condition: colorectal or oesogastric adenocarcinoma | ||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: FR (Ongoing) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2017-000292-83 | Sponsor Protocol Number: Tallisur | Start Date*: 2017-08-30 |
Sponsor Name:Servier Deutschland GmbH | ||
Full Title: Prospective, Multicenter, Open-label Phase IV trial of Trifluridine/Tipiracil to Evaluate the Health-related Quality of Life in Patients with Metastatic Colorectal Cancer | ||
Medical condition: Histologically or cytologically confirmed UICC stage IV carcinoma of colon or rectum with metastasis (metastatic colorectal cancer) with need for treatment due to progression | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: DE (Completed) | ||
Trial results: View results |
EudraCT Number: 2012-000109-66 | Sponsor Protocol Number: TPU-TAS-102-301 | Start Date*: 2012-12-10 | |||||||||||
Sponsor Name:Taiho Oncology, Inc. | |||||||||||||
Full Title: RANDOMIZED, DOUBLE-BLIND, PHASE 3 STUDY OF TAS-102 PLUS BEST SUPPORTIVE CARE (BSC) VERSUS PLACEBO PLUS BSC IN PATIENTS WITH METASTATIC COLORECTAL CANCER REFRACTORY TO STANDARD CHEMOTHERAPIES | |||||||||||||
Medical condition: Refractory metastatic colorectal cancer | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Completed) DE (Completed) SE (Completed) AT (Completed) ES (Completed) IE (Completed) CZ (Completed) BE (Completed) IT (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2022-000273-81 | Sponsor Protocol Number: UC-GIG-2203 | Start Date*: 2022-09-13 | |||||||||||||||||||||
Sponsor Name:UNICANCER | |||||||||||||||||||||||
Full Title: Randomised phase II study evaluating trifluridine/tipiracil plus oxaliplatin versus FOLFOX in patients with gastric, oesophagus or gastroesophageal junction adenocarcinoma locally advanced, recurre... | |||||||||||||||||||||||
Medical condition: Patients with gastric, oesophagus or gastroesophageal junction adenocarcinoma locally advanced, recurrent or metastatic, ineligible for triplet chemotherapy. | |||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||
Trial protocol: FR (Ongoing) | |||||||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2015-004544-18 | Sponsor Protocol Number: CL2-95005-002 | Start Date*: 2016-03-23 | |||||||||||
Sponsor Name:Institut de Recherches Internationales Servier | |||||||||||||
Full Title: An open-label, randomised, non-comparative phase 2 study evaluating S 95005 (TAS-102) plus bevacizumab and capecitabine plus bevacizumab in patients with previously untreated metastatic COlorectal ... | |||||||||||||
Medical condition: Metastatic colorectal cancer | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Completed) DE (Completed) DK (Completed) NL (Completed) BE (Completed) ES (Completed) FR (Completed) IT (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2019-000276-41 | Sponsor Protocol Number: SUMO | Start Date*: 2020-03-05 |
Sponsor Name:Erasmus MC | ||
Full Title: Study on the effects of an OCT2/MATE1 substrate (metformin) and inhibitor (cimetidine) on the exposure of trifluridine/tipiracil (Lonsurf®) in patients with metastatic colorectal cancer (mCRC). | ||
Medical condition: patients with mCRC with an indication for lonsurf treatment. | ||
Disease: | ||
Population Age: | Gender: | |
Trial protocol: NL (Completed) | ||
Trial results: (No results available) |
EudraCT Number: 2018-002936-26 | Sponsor Protocol Number: 17-157 | Start Date*: 2019-11-28 |
Sponsor Name:Heinrich-Heine-University Düsseldorf | ||
Full Title: Efficacy and safety of Trifluridine/Tipiracil in combination with Irinotecan as a second line therapy in patients with Cholangiocarcinoma | ||
Medical condition: Patients with advanced, non resectable or metastatic cholangio- and gallbladder carcinoma after failure to respond to a previous gemcitabine treatment. | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: DE (Completed) | ||
Trial results: (No results available) |
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