Flag of the European Union EU Clinical Trials Register Help

Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44381   clinical trials with a EudraCT protocol, of which   7393   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
    Select Country:
    		 Select Age Range:
    Select Trial Status:
    		 Select Trial Phase:
    Select Gender:
    Select Date Range:
    to
    Select Rare Disease:
    IMP with orphan designation in the indication
    Orphan Designation Number:
    Results Status:
    Clear advanced search filters
     
    7,393 result(s) found. Displaying page 214 of 370.
    «« First « Previous 210  211  212  213  214  215  216  217  218  Next» Last»»
    EudraCT Number: 2004-001735-37 Sponsor Protocol Number: FL-CR001 Start Date*: 2006-02-16
    Sponsor Name:FERRING ARZNEIMITTEL Ges.m.b.h. CEE AUSTRIA
    Full Title: AN OPEN LABEL STUDY OF ORAL DESMOPRESSIN IN CHILDREN AGED 5 TO 15 YEARS WITH PRIMARY NOCTURAL ENURESIS
    Medical condition: Primary noctural enuresis
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-022172-30 Sponsor Protocol Number: FENT-PED-01 Start Date*: 2010-09-10
    Sponsor Name:Faculty of pharmacy, University of Ljubljana
    Full Title: ODNOS MED FARMAKOKINETIKO IN FARMAKODINAMIKO FENTANILA PRI OTROCIH (Pharmacokinetics and pharmcodynamics of fentanyl in pediatric population)
    Medical condition: Children aged less than 2 years that are hospitalized due to bronchiolitis and need sedation and analgesia with fentanyl.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10006448 Bronchiolitis PT
    12.1 10038718 Respiratory syncytial virus bronchiolitis PT
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000467-23 Sponsor Protocol Number: 1 Start Date*: 2007-08-23
    Sponsor Name:Erasmus MC
    Full Title: Maternal and fetal haemodynamic response to Nifedipine tocolysis in normotensive pregnant women.
    Medical condition: A more detailed investigation of the haemodynamic effect on the mother and fetus of Nifedipine tocolysis . Tocolysis will be used to facilitate external cephalic version for breech presentation at ...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10006356 Breech presentation LLT
    9.1 10048773 Tocolysis LLT
    9.1 10013596 Doppler ultrasound LLT
    9.1 10053094 Doppler echocardiography LLT
    Population Age: In utero, Under 18, Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-005648-31 Sponsor Protocol Number: TL16102021 Start Date*: 2022-06-14
    Sponsor Name:Turun Yliopistollinen keskussairaala
    Full Title: Vastasyntyneen aivojen kontrastiultraääni- ja elastografiatutkimus
    Medical condition: Vastasyntyneiden hypoksis-iskeeminen aivovaurio, keskosuus, vastasyntyneiden aivoinfarkti, muista kuin keskushermostoperäisistä syistä vastasyntyneiden teho-osastolla hoidossa olevat lapset, vastas...
    Disease:
    Population Age: Newborns, Under 18 Gender: Male, Female
    Trial protocol: FI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2008-003287-18 Sponsor Protocol Number: PET-FRAX-001 Start Date*: 2008-09-17
    Sponsor Name:University Antwerp [...]
    1. University Antwerp
    2. University Hospital Leuven gasthuisberg
    Full Title: Functional consequences of decreased RNA expression of certain GABA(A) receptor subunits in fragile X patients using Positron Emission Tomography and [11C]flumazenil.
    Medical condition: Fragile X syndrome is the most common form of inherited mental retardation with a prevalence of 1/4000 males and 1/6000 females. Patients are characterized by a mild to severe form of cognitive imp...
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-000075-27 Sponsor Protocol Number: HPN-100-021 Start Date*: 2016-03-07
    Sponsor Name:Horizon Therapeutics, LLC
    Full Title: A Randomised, Controlled, Open-Label Parallel Arm Study of the Safety, Pharmacokinetics and Ammonia Control of RAVICTI® (Glycerol Phenylbutyrate [GPB]) Oral Liquid and Sodium Phenylbutyrate (NaPBA)...
    Medical condition: Urea Cycle Disorders (UCDs)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000161833 10013373 Disorders of urea cycle metabolism LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed) AT (Completed) IT (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2007-007583-20 Sponsor Protocol Number: 111702A Start Date*: 2008-01-31
    Sponsor Name:Marja-Liisa Korhonen
    Full Title: Yleisanestesian-sevofluraani-induktion aiheuttamat EEG-muutokset alle 2-vuotiailla lapsilla
    Medical condition: Tutkittavat ovat terveitä lapsia, joille tehdään kyynelteiden sondeeraus-toimenpide.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023621 Lacrimal disorders HLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-004426-24 Sponsor Protocol Number: TREAT-LMNA Start Date*: 2020-07-06
    Sponsor Name:AZIENDA OSPEDALIERO-UNIVERSITARIA PISANA
    Full Title: Deflazacort TREATment in LMNA related congenital muscular dystrophy: study of clinical effectiveness and search for reliable biomarkers.
    Medical condition: Congenital Muscolar distrophy LMNA related
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10003718 Atrophy skeletal muscle LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-000715-25 Sponsor Protocol Number: M15-340 Start Date*: 2019-04-16
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: An Open-Label Multiple-Dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Upadacitinib in Pediatric Subjects with Polyarticular Course Juvenile Idiopathic Arthritis
    Medical condition: Polyarticular Course Juvenile Idiopathic Arthritis
    Disease: Version SOC Term Classification Code Term Level
    23.1 10028395 - Musculoskeletal and connective tissue disorders 10059176 Juvenile idiopathic arthritis PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Trial now transitioned) ES (Restarted) IT (Trial now transitioned) SE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2022-001092-14 Sponsor Protocol Number: TIGEM5_USH Start Date*: 2023-10-12
    Sponsor Name:FONDAZIONE TELETHON
    Full Title: A phase I/II open label, dose escalation study of sub-retinal administration of a “mixture of two adeno-associated viral vectors of serotype 8 containing the 5 ´- half sequence of the human MYO7A ...
    Medical condition: Usher syndrome (USH) is characterized by the association of sensorineural hearing loss, Retinitis Pigmentosa (RP), and, in some cases, vestibular dysfunction. It is the most frequent cause of deaf-...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10063396 Usher's syndrome PT
    20.0 10010331 - Congenital, familial and genetic disorders 10063396 Usher's syndrome PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-005264-60 Sponsor Protocol Number: CHF6467-OPG Start Date*: 2021-11-26
    Sponsor Name:FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS UNIVERSITA' CATTOLICA DEL SACRO CUORE
    Full Title: Safety and Efficacy of multiple doses of the PAINLESS Nerve Growth Factor CHF6467 in subjects with Optic Pathway Glioma (OPG). A randomized clinical trial (RCT)
    Medical condition: Optic pathway glioma - optic neuropathy
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10073338 Optic glioma PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2021-004031-86 Sponsor Protocol Number: CEST-JIA Start Date*: 2021-12-21
    Sponsor Name:FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO
    Full Title: “A randomized, two-armed, single-blind, parallel, active controlled, and non-inferiority clinical trial to Compare Efficacy and Safety of anti TNF-alfa biosimilar molecules to the originators in ch...
    Medical condition: Juvenile Idiopathic Arthritis
    Disease: Version SOC Term Classification Code Term Level
    23.1 10028395 - Musculoskeletal and connective tissue disorders 10059176 Juvenile idiopathic arthritis PT
    23.1 10028395 - Musculoskeletal and connective tissue disorders 10059176 Juvenile idiopathic arthritis PT
    23.1 10028395 - Musculoskeletal and connective tissue disorders 10059176 Juvenile idiopathic arthritis PT
    23.1 10028395 - Musculoskeletal and connective tissue disorders 10059176 Juvenile idiopathic arthritis PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2022-002668-65 Sponsor Protocol Number: PTC743-NEU-003e-FA Start Date*: Information not available in EudraCT
    Sponsor Name:PTC Therapeutics, Inc.
    Full Title: Long-Term Open-Label Study to Assess the Safety and Efficacy of Vatiquinone in Patients With Friedreich Ataxia
    Medical condition: Friedreich Ataxia (FA)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10017374 Friedreich's ataxia PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Trial now transitioned) FR (Trial now transitioned) ES (Ongoing) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2019-002778-30 Sponsor Protocol Number: GR-2018-12367476 Start Date*: 2022-01-12
    Sponsor Name:IRCCS, OSPEDALE PEDIATRICO BAMBINO GESÙ DI ROMA
    Full Title: Efficacy and safety of memantine as antimanic and mood-stabilizing medication for adolescents with Bipolar Disorder: a multi-center, randomized, double-blind, placebo-controlled clinical trial
    Medical condition: Bipolar Disorder
    Disease: Version SOC Term Classification Code Term Level
    21.1 10037175 - Psychiatric disorders 10057667 Bipolar disorder PT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2021-005754-28 Sponsor Protocol Number: PAPA-Can Start Date*: 2023-07-10
    Sponsor Name:IRCCS ISTITUTO GIANNINA GASLINI
    Full Title: A double-blind, placebo-controlled, randomized withdrawal study of canakinumab in pyogenic sterile arthritis pyoderma gangrenosum and acne (PAPA) syndrome
    Medical condition: PAPA syndrome (Pyogenic Arthritis, Pyoderma gangrenosum and Acne)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004850 10072225 PAPA syndrome LLT
    20.0 100000004850 10072225 PAPA syndrome LLT
    20.0 100000004850 10072225 PAPA syndrome LLT
    20.0 100000004850 10072225 PAPA syndrome LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-003626-91 Sponsor Protocol Number: CAFSP01 Start Date*: 2019-04-09
    Sponsor Name:AZIENDA OSPEDALIERO-UNIVERSITARIA CAREGGI
    Full Title: CAFFEINE TREATMENT IN DELIVERY ROOM FOR VERY PRETERM INFANTS : A FEASIBILITY STUDY
    Medical condition: 25+0-29+6 gestational age preterm infants at risk of respiratory distress syndrome with no need of mechanical ventilation in delivery room.
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004868 10021734 Infant premature LLT
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-003425-18 Sponsor Protocol Number: AITT2014/3 Start Date*: 2014-11-19
    Sponsor Name:Debreceni Egyetem Klinikai Központ
    Full Title:
    Medical condition:
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-003247-70 Sponsor Protocol Number: UZAPED1 Start Date*: 2007-10-29
    Sponsor Name:Belgian Study Group for Pediatric Endocrinology
    Full Title: Efficacy and safety of a 4 year combination therapy of growth hormone and gonadotropin- releasing hormone agonist in children with a short predicted height.
    Medical condition: predicted short stature
    Disease: Version SOC Term Classification Code Term Level
    9.1 10066333 Idiopathic short stature LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-006989-28 Sponsor Protocol Number: extended2008 Start Date*: 2009-01-16
    Sponsor Name:HUCH, Hospital for Children and Adolescents
    Full Title: EXTENDED ANGIOCOMB Antiangiogenetic therapy for pediatric malignancies with no conventional treatment modalities left
    Medical condition: Pediatric malignancies with no conventional treatment modalities left
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2024-000341-27 Sponsor Protocol Number: DEN-324 Start Date*: 2024-12-13
    Sponsor Name:Takeda
    Full Title: A Randomized, Double-Blind, Placebo-Controlled (Participants aged 18 to 60 years) and Open-Label (Participants aged 4 to 17 years), Phase 2/3 Trial to Evaluate the Immunogenicity and Safety of 2 do...
    Medical condition: Dengue fever
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021881 - Infections and infestations 10012312 Dengue fever virus infection LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: (No results available)
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    «« First « Previous 210  211  212  213  214  215  216  217  218  Next» Last»»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Sat Feb 14 00:35:09 CET 2026 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA