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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44338   clinical trials with a EudraCT protocol, of which   7368   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,338 result(s) found. Displaying page 1,452 of 2,217.
    EudraCT Number: 2011-002443-10 Sponsor Protocol Number: 2011035 Start Date*: 2011-06-23
    Sponsor Name:Procter & Gamble Technical Centres Ltd., UK
    Full Title: A Randomized, Open-Label, Single-Dose, Parallel Group Study to Evaluate the Utility of Magnetic Resonance Imaging (MRI) in Demonstrating the Nasal Decongestant Efficacy of an Active Control (Vicks®...
    Medical condition: Nasal Congestion due to the common cold or hay fever
    Disease: Version SOC Term Classification Code Term Level
    13.1 10038738 - Respiratory, thoracic and mediastinal disorders 10028735 Nasal congestion PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-002612-14 Sponsor Protocol Number: TMP-0517 Start Date*: 2019-06-25
    Sponsor Name:Fraunhofer Gesellschaft for its Institute Fraunhofer Institute for Molecular Biology and Applied Ecology (IME)
    Full Title: Preliminary efficacy and safety of Apremilast in the treatment of acne conglobata: A phase II, single centre, open label, proof of concept study for the treatment of acne conglobata with the PDE-4 ...
    Medical condition: Mild to severe Acne conglobata in adults (ages 18 to 65 years, inclusive)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10040785 - Skin and subcutaneous tissue disorders 10000501 Acne conglobata PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-003761-28 Sponsor Protocol Number: VP-00525 Start Date*: 2015-12-22
    Sponsor Name:Calibra Medical, Inc.
    Full Title: GLYCEMIC CONTROL AND TREATMENT SATISFACTION USING FINESSE VERSUS PEN FOR INITIATING BOLUS INSULIN DOSING IN TYPE 2 DIABETES MELLITUS PATIENTS NOT ACHIEVING GLYCEMIC TARGETS ON BASAL INSULIN WITH/WI...
    Medical condition: Type 2 Diabetes Mellitus (T2DM)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-003334-19 Sponsor Protocol Number: 804P302 Start Date*: 2010-07-29
    Sponsor Name:Supernus Pharmaceuticals, Inc.
    Full Title: Multicenter, Open-Label Extension Study to Evaluate the Long-Term Safety and Tolerability of Oxcarbazepine Extended-Release (OXC XR) as Adjunctive Therapy in Subjects with Refractory Partial Epilep...
    Medical condition: Treatment of seizures of partial origin in subjects with refractory epilepsy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015037 Epilepsy LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BG (Completed)
    Trial results: View results
    EudraCT Number: 2015-005704-29 Sponsor Protocol Number: LUNG-NEPA Start Date*: 2016-06-08
    Sponsor Name:CONSORZIO ONCOTECH
    Full Title: A standard regimen of dexamethasone in comparison to two dex-sparing regimens in addition to NEPA in preventing CINV in na¿ve NSCLC patients to be treated with cisplatin based chemotherapy: a three...
    Medical condition: Chemotherapy-Induced Nausea and Vomiting (CINV) in non-small cell lung cancer (NSCLC) patients receiving a cisplatin-based chemotherapy
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10008443 Chemotherapy antiemetic prophylaxsis LLT
    21.1 10042613 - Surgical and medical procedures 10054133 Prophylaxis of nausea and vomiting PT
    21.1 10042613 - Surgical and medical procedures 10008448 Chemotherapy induced emesis prophylaxis LLT
    21.1 10042613 - Surgical and medical procedures 10049091 Chemotherapy antiemetic prophylaxis LLT
    21.1 10042613 - Surgical and medical procedures 10036899 Prophylaxis against chemotherapy induced vomiting LLT
    21.1 10042613 - Surgical and medical procedures 10008449 Chemotherapy inducted emesis prophylaxis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2018-001887-46 Sponsor Protocol Number: STH18493 Start Date*: 2018-11-08
    Sponsor Name:Sheffield Teaching Hospitals NHS Foundation Trust
    Full Title: A Phase II, Placebo Controlled, Double Blind, Randomised Clinical Trial to assess the safety and tolerability Of 30mg/kg daily Ursodeoxycholic Acid (UDCA) in Patients with Parkinson’s Disease (PD)
    Medical condition: Parkinson’s disease (PD)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10061536 Parkinson's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2017-002824-26 Sponsor Protocol Number: VHIO17001 Start Date*: 2018-02-23
    Sponsor Name:Vall d' Hebron Institute of Oncology (VHIO)
    Full Title: Phase II trial of Pembrolizumab in combination with Doxorubicin in Advanced, Recurrent or Metastatic Endometrial Cancer (TOPIC)
    Medical condition: Advanced, Recurrent or Metastatic Endometrial Cancer
    Disease: Version SOC Term Classification Code Term Level
    12.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10007129 Cancer-related morbidities HLGT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2012-005197-63 Sponsor Protocol Number: U1111-1128-8762 Start Date*: 2013-02-25
    Sponsor Name:Ana M. Wägner
    Full Title: Effect of liraglutide on physical performance: a randomised, double-blind, controlled study in patiens with type 2 diabetes.
    Medical condition: Patients with Diabetes type 2.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2015-003049-24 Sponsor Protocol Number: PHY201501 Start Date*: 2016-07-27
    Sponsor Name:Uppsala University, Department of Medical Sciences
    Full Title: The Precision Hypertension Care study
    Medical condition: Hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2012-005332-29 Sponsor Protocol Number: D-Vitaal1.0 Start Date*: 2013-01-23
    Sponsor Name:VU University Medical Centre
    Full Title: Prevention of depression and poor physical function in older persons with vitamin D supplementation
    Medical condition: depressive symptoms, poor physical functioning.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2017-004235-36 Sponsor Protocol Number: EWO-ISO-2017/2 Start Date*: 2018-09-27
    Sponsor Name:Ewopharma AG
    Full Title: A phase 4, randomized, open label multi-centre clinical study to evaluate efficacy of Isoprinosine® in female subjects with low-grade cervical dysplasia caused by HrHPV.
    Medical condition: Low-grade cervical dysplasia caused by HrHPV
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2013-004278-88 Sponsor Protocol Number: GA28950 Start Date*: 2014-06-19
    Sponsor Name:F. Hoffmann-La Roche Ltd
    Full Title: PHASE III, DOUBLE BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY OF THE EFFICACY AND SAFETY OF ETROLIZUMAB DURING INDUCTION AND MAINTENANCE IN PATIENTS WITH MODERATE TO SEVERE ACTIVE ULCERATIVE COLIT...
    Medical condition: Ulcerative colitis (UC)
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004856 10045365 Ulcerative colitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed) GR (Completed) DE (Completed) CZ (Completed) DK (Completed) BE (Completed) HU (Completed) AT (Completed) ES (Completed) NL (Completed) IT (Completed) FR (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2014-004485-21 Sponsor Protocol Number: HE9A/14 Start Date*: 2015-04-03
    Sponsor Name:Hellenic Cooperative Oncology Group
    Full Title: A study of cabazitaxel treatment in castration resistant bone metastatic prostate cancer patients evaluating the tumor microenvironment
    Medical condition: Castration resistant bone metastatic prostate cancer
    Disease: Version SOC Term Classification Code Term Level
    18.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10036909 Prostate cancer metastatic PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GR (Completed)
    Trial results: View results
    EudraCT Number: 2006-006088-22 Sponsor Protocol Number: Gastripec-I Start Date*: 2011-03-28
    Sponsor Name:Klinik für Chirurgie, Charité Campus Virchow-Klinikum
    Full Title: Prospective multicenter phase III clinical trial using cytoreductive surgery with hyperthermic intraoperative chemotherapy (HIPEC) after preoperative chemotherapy in patients with peritoneal carc...
    Medical condition: Peritoneal carcinomatosis of gastric cancer incl. adenocarcinoma of the esophagogastreal junction
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10042080 Stomach cancer LLT
    20.0 100000004864 10042081 Stomach cancer in situ LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-016682-28 Sponsor Protocol Number: ARhiSi-2 Start Date*: Information not available in EudraCT
    Sponsor Name:Bionorica AG
    Full Title: A multi-centre, double-blind, placebo-controlled, randomised, parallel group study to assess the efficacy and safety of a herbal medicinal product (dry extract BNO-1016) in patients with acute rhi...
    Medical condition: Acute rhinosinusitis
    Disease: Version SOC Term Classification Code Term Level
    12.0 10052106 Rhinosinusitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-024428-10 Sponsor Protocol Number: 10-PP-19 Start Date*: Information not available in EudraCT
    Sponsor Name:CHU de NICE
    Full Title: Traitement des épidermolyses bulleuses simples de type Dowling Maera par l'érythromicine orale
    Medical condition: Dowling Maera's bullous epidermolysis is a génodermatose with autosomique dominant transmission owed to transfers of the genes coding for keratins. It results from it a cutaneous fragility very sev...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10056508 Acquired epidermolysis bullosa LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: View results
    EudraCT Number: 2010-023485-53 Sponsor Protocol Number: IJG-PAR-2010 Start Date*: 2011-04-20
    Sponsor Name:IDIAP JORDI GOL I GURINA
    Full Title: Evaluation of the relationship between effervescent acetaminophen and blood pressure. A clinical trial.
    Medical condition: Evaluation of whether paracetamol effervescent formulation increases blood pressure compared with effervescent paracetamol formulation does not
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2013-005039-26 Sponsor Protocol Number: P130404 Start Date*: 2014-03-10
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004866 10043098 Takayasu's disease LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2015-004139-11 Sponsor Protocol Number: VAC52150EBL4001 Start Date*: Information not available in EudraCT
    Sponsor Name:Janssen Vaccines & Prevention B.V.
    Full Title: A Multicountry, Prospective, Clinical Safety Study of Subjects Exposed to the Candidate Ebola Vaccines Ad26.ZEBOV and/or MVA-BN-Filo
    Medical condition: Ebola
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10014071 Ebola disease PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) FR (Completed)
    Trial results: View results
    EudraCT Number: 2010-021452-26 Sponsor Protocol Number: P081217 Start Date*: 2010-09-20
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Crise Rénale sclérodermique : amélioration du pronostic par adjonction de Bosentan au traitement de référence de la maladie
    Medical condition: Les patients inclus dans l'étude seront des patients atteints de sclérodermie systémique (définie selon les critères de la classification de l'ACR et/ou de Leroy et Medsger) et présentant une crise...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10062553 scleroderma renal crisis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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