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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,380 result(s) found. Displaying page 525 of 2,219.
    EudraCT Number: 2013-005529-22 Sponsor Protocol Number: H-6-2013-011 Start Date*: 2014-03-21
    Sponsor Name:Rigshospitalet
    Full Title: Platelet inhibition in comatose patients receiving oral anti platelet therapy through a naso-gastric tube after undergoing acute percutaneous coronary intervention
    Medical condition: Patients surviving cardiac arrest and undergoing percutaneous coronary intervention
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004849 10067273 Acute transmural myocardial infarction LLT
    16.1 100000004849 10064347 Non ST segment elevation myocardial infarction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-005569-38 Sponsor Protocol Number: CLS003-CO-PR-001 Start Date*: 2014-02-17
    Sponsor Name:Cutanea Life Sciences
    Full Title: A phase I/IIa open-label First-in-Human study to assess safety and pharmacokinetics and explore biomarker effects of topical ionic contra-viral therapy (ICVT) comprised of digoxin and furosemide in...
    Medical condition: Cutaneous warts
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004862 10033724 Papilloma viral infections HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-003896-20 Sponsor Protocol Number: 3667 Start Date*: 2013-02-14
    Sponsor Name:The Royal Marsden NHS Foundation Trust [...]
    1. The Royal Marsden NHS Foundation Trust
    2. The Institute of Cancer Research
    Full Title: TAX-TORC: A Phase I multi-centre trial of the combination of AZD2014 (dual TORC1 and TORC2 inhibitor) and weekly paclitaxel in patients with solid tumours
    Medical condition: Solid tumours
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-003942-33 Sponsor Protocol Number: M13-796 Start Date*: 2013-05-03
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: A Phase 2b, Randomized, Double-Blind, Placebo-Controlled, Safety and Efficacy Trial of Multiple Dosing Regimens of ABT-719 for the Prevention of Acute Kidney Injury in Subjects Undergoing High Risk...
    Medical condition: Acute Kidney Injury
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004857 10069339 Acute kidney injury LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2013-000359-42 Sponsor Protocol Number: ML28695 Start Date*: 2013-09-12
    Sponsor Name:ROCHE HELLAS S.A.
    Full Title: Multicenter, open label, phase IIIb study to evaluate the safety and tolerability of subcutaneous tocilizumab as monotherapy and/or in combination with methotrexate or other non-biologic disease mo...
    Medical condition: Rheumatoid Arthritis
    Disease: Version SOC Term Classification Code Term Level
    16.0 10028395 - Musculoskeletal and connective tissue disorders 10039073 Rheumatoid arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: View results
    EudraCT Number: 2013-000364-28 Sponsor Protocol Number: 00/0594-LINARI Start Date*: 2013-05-16
    Sponsor Name:Profil Institut für Stoffwechselforschung GmbH
    Full Title: Effects of Linagliptin on active GLP-1 concentrations in subjects with renal impairment
    Medical condition: Type 2 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    18.0 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-004403-13 Sponsor Protocol Number: PDT002/12 Start Date*: 2013-08-27
    Sponsor Name:Medizinische Universität Wien, Univ. Klinik für Dermatologie
    Full Title: Placebo-controlled cross-over study on the efficacy of a non-steroidal antirheumatic drug for pain reduction during photodynamic therapy of actinic keratoses
    Medical condition: actinic keratosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-004770-25 Sponsor Protocol Number: CLOTILDIA Start Date*: 2012-10-30
    Sponsor Name:UNIVERSITA' CAMPUS BIOMEDICO
    Full Title: CLOpidogrel versus TIcagreLor for antiplatelet maintenance in DIAbetic patients (CLOTILDIA)
    Medical condition: patients with type 2 diabetes mellitus and known coronary artery disease on dual antiplatelet therapy (aspirin 100 mg qd and clopidogrel 75 mg qd)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10007541 Cardiac disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-000801-21 Sponsor Protocol Number: 20130218 Start Date*: 2014-08-26
    Sponsor Name:Academic Medical Center
    Full Title: Stimulation of the ovaries in women with breast cancer undergoing fertility preservation: alternative versus standard stimulation protocols; the STIM-trial
    Medical condition: Ovarian stimulation in women with breast cancer prior to chemotherapy
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-000819-25 Sponsor Protocol Number: 43712 Start Date*: 2013-10-22
    Sponsor Name:Leiden University Medical Center
    Full Title: Autologous BM derived MSCs in combination with everolimus to preserve renal structure and function in renal recipients
    Medical condition: renal recipients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-000858-22 Sponsor Protocol Number: AFLIBC06561 Start Date*: 2013-09-12
    Sponsor Name:Sanofi-Aventis Groupe
    Full Title: A Single-Arm, Open Label Study of Aflibercept as Maintenance Therapy Following Induction with Aflibercept in Combination with XELOX, as First-Line Treatment for Metastatic Colorectal Cancer Patient
    Medical condition: Colorectal cancer metastatic
    Disease: Version SOC Term Classification Code Term Level
    16.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10052358 Colorectal cancer metastatic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2016-003582-25 Sponsor Protocol Number: NL59128 Start Date*: 2017-01-23
    Sponsor Name:University Medical Center Groningen
    Full Title: The added effect of oral ondansetron to care-as-usual on persisting vomiting in children aged 6 months to 6 years, presenting at primary care out of hours service with acute gastro-enteritis and co...
    Medical condition: Gastroenteritis
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-001369-28 Sponsor Protocol Number: 880 Start Date*: 2014-10-30
    Sponsor Name:Gateshead Health NHS Foundation Trust
    Full Title: THYRoxine in Acute Myocardial Infarction (ThyrAMI)
    Medical condition: Hypothyroidism and Acute Myocardial Infarction
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10000891 Acute myocardial infarction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-001435-13 Sponsor Protocol Number: CHUBX2014/22 Start Date*: 2016-05-19
    Sponsor Name:CHU de Bordeaux
    Full Title: Description of the ability to learn how to handle inhaler devices in COPD
    Medical condition: Chronic Obstructive Pulmonary Disease (COPD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-001421-41 Sponsor Protocol Number: TWOProtocolv1.0 Start Date*: 2018-05-22
    Sponsor Name:University of Oxford
    Full Title: The TWO Study: Transplantation Without Over-immunosuppression. A Phase IIb Trial of Regulatory T Cells in Renal Transplantation.
    Medical condition: Renal (allograft) transplant
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10050436 Prophylaxis against renal transplant rejection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2014-001174-34 Sponsor Protocol Number: B1851140 Start Date*: 2016-07-13
    Sponsor Name:Pfizer Inc.
    Full Title: A PHASE 4/3, OPEN-LABEL, SINGLE-ARM, MULTICENTER STUDY TO DESCRIBE THE SAFETY AND IMMUNOGENICITY OF 13-VALENT PNEUMOCOCCAL CONJUGATE VACCINE IN ADULTS 50 TO 65 YEARS OF AGE AND IN CHILDREN 6 TO 17 ...
    Medical condition: Pneumococcal infection
    Disease: Version SOC Term Classification Code Term Level
    19.0 10021881 - Infections and infestations 10061353 Pneumococcal infection PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2012-002426-70 Sponsor Protocol Number: 104005 Start Date*: 2015-06-01
    Sponsor Name:GlaxoSmithKline Biologicals
    Full Title: Phase III b, open, randomised, multicenter study to evaluate the immunogenicity and safety of GlaxoSmithKline Biologicals’ combined diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated po...
    Medical condition: Primary immunisation of healthy infants in the first year of life against diphtheria, tetanus, pertussis, hepatitis B, polio, Haemophilus influenzae type b diseases.
    Disease:
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2014-004662-26 Sponsor Protocol Number: LACAC_L_04298 Start Date*: 2015-03-25
    Sponsor Name:Sanofi
    Full Title: Safety Dermatological Evaluation: genital Mucosa Irritation - Product tested: Dermacyd PH_DETINLYN Sweet Flower.
    Medical condition: Healthy volunteers (hygiene)
    Disease: Version SOC Term Classification Code Term Level
    17.1 10042613 - Surgical and medical procedures 10053339 Routine health maintenance PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2014-003386-22 Sponsor Protocol Number: PRX302-2-07 Start Date*: 2015-01-19
    Sponsor Name:Sophiris Bio Corp
    Full Title: A Single Centre, Open Label, Phase IIa Study, Evaluating the Safety and Tolerability of Targeted Intraprostatic Administration of PRX302 to Treat Men with Histologically Proven, Clinically Signific...
    Medical condition: Prostate cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-001941-25 Sponsor Protocol Number: 2014-002 Start Date*: 2014-12-16
    Sponsor Name:Rigshospitalet 2121
    Full Title: Pilot Study with Treatment of Short Bowel Syndrome Patients with dipeptidyl-peptidase 4 inhibitor, Sitagliptin (Januvia®)
    Medical condition: Short Bowel Syndrome with intestinal failure (SBS IF)
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004856 10022683 Intestinal malabsorption LLT
    17.1 100000004856 10036430 Post surgical malabsorption NOS LLT
    17.1 100000004856 10042822 Syndrome malabsorption LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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