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Clinical trials for Percutaneous coronary intervention

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44338   clinical trials with a EudraCT protocol, of which   7368   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    237 result(s) found for: Percutaneous coronary intervention. Displaying page 6 of 12.
    EudraCT Number: 2014-005462-30 Sponsor Protocol Number: MDCO-APO-14-01 Start Date*: 2016-10-26
    Sponsor Name:The Medicines Company
    Full Title: A multiple dose, dose-finding, placebo controlled, double blind, randomized trial to compare the effect of treatment on plaque burden as determined by intravascular ultrasound and evaluate the effi...
    Medical condition: acute coronary syndrome
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-000506-22 Sponsor Protocol Number: DRI6624 Start Date*: 2006-05-24
    Sponsor Name:Sanofi aventis recherche & développement
    Full Title: A randomized, double-blind, triple-dummy, dose-ranging study, including an active control of unfractionated heparin and eptifibatide, to evaluate the clinical efficacy and safety of otamixaban, in ...
    Medical condition: Coronary desease in patients with non-ST elevation acute coronary syndrome and planned early invasive strategy
    Disease: Version SOC Term Classification Code Term Level
    8.1 10051592 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) AT (Completed) DK (Completed) DE (Completed) SK (Completed) HU (Completed) FI (Completed) EE (Completed) IT (Completed) PT (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2018-003676-12 Sponsor Protocol Number: ATH3G10-006 Start Date*: 2018-12-17
    Sponsor Name:Athera Biotechnologies AB
    Full Title: A phase IIa, placebo-controlled, double blind, randomised multicentre pilot study to investigate the efficacy, safety and tolerability of the monoclonal antibody ATH3G10 in patients with ST-elevati...
    Medical condition: Treatment of ST-elevated myocardial infarction (STEMI) after percutaneous intervention (PCI)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10007541 Cardiac disorders SOC
    20.0 10007541 - Cardiac disorders 10064346 STEMI LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DK (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2011-000214-19 Sponsor Protocol Number: D5130L00006 Start Date*: 2011-07-13
    Sponsor Name:AstraZeneca
    Full Title: A 30 day international, randomized, parallel-group, double-blind, placebo-controlled phase IV study to evaluate efficacy and safety of pre-hospital vs. in-hospital initiation of ticagrelor therapy ...
    Medical condition: myocardial infarction, STEMI patients planned for Percutaneous Coronary Intervention
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10051592 Acute coronary syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) AT (Completed) SE (Completed) DK (Completed) NL (Completed) ES (Completed) IT (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2011-000430-11 Sponsor Protocol Number: RFBU11-I Start Date*: 2011-10-06
    Sponsor Name:G.I.S.E. - SOCIETA'' ITALIANA CARDIOLOGIA INVASIVA
    Full Title: Minimizing Adverse haemmhorragic events by TRansradial access site and systemic Implementation of angioX (MATRIX)
    Medical condition: Real world ACS both Non-ST segment elevation and ST-segment elevation patients undergoing coronary angiography±PCI.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10051592 Acute coronary syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing) NL (Ongoing) SE (Ongoing) ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-001636-22 Sponsor Protocol Number: TROPICALACS Start Date*: 2013-08-26
    Sponsor Name:Hospital of the University of Munich, Grosshadern
    Full Title: A prospective, randomized, parallel-group, open label, non-inferiority, multicenter trial of a 12 month vs. a short-term platelet function testing guided prasugrel therapy in acute coronary syndrom...
    Medical condition: Troponin positive acute coronary syndrome after successful percutaneous coronary intervention with an indication for a standard treatment of 12 month with prasugrel
    Disease: Version SOC Term Classification Code Term Level
    19.1 10007541 - Cardiac disorders 10051592 Acute coronary syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) HU (Completed) AT (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2010-022604-45 Sponsor Protocol Number: 46908990 Start Date*: 2011-03-25
    Sponsor Name:Odense Universitetshospital
    Full Title: EFFEKTEN AF EZETIMIBE SOM TILLÆG TIL OPTIMAL STATINBEHANDLING PÅ PLAQUE-KOMPOSITIONEN HOS PATIENTER MED AKUT MYOKARDIEINFARKT - VURDERET MED OPTICAL COHERENCE TOMOGRAPHY OG INTRAVASKULÆR ULTRALYD (...
    Medical condition: Patienter med iskæmisk hjertesygdom og med akut myokardieinfarkt, hvor en drug eluting stent af type "Resolute" er anvendt. Forholdene omkring den indsatte stent og et andet ikke umiddelbart behand...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10000891 Acute myocardial infarction LLT
    12.1 10011095 Coronary atherosclerosis of native coronary artery LLT
    12.1 10065608 Percutaneous coronary intervention LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2021-000573-80 Sponsor Protocol Number: APHP201075 Start Date*: 2021-05-10
    Sponsor Name:APHP DRCI
    Full Title: Acute Myocardial infarction Upbound to percutaneous coronary intervention, immediately (STEMI) or in the Next three Days (NSTEMI), and randomized to Subcutaneous Evolocumab or Normal strategies to ...
    Medical condition:
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Trial now transitioned) DE (Trial now transitioned) IT (Trial now transitioned) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-000061-21 Sponsor Protocol Number: I1V-MC-EIAN Start Date*: 2012-10-25
    Sponsor Name:Eli Lilly and Company
    Full Title: Protocol I1V-MC-EIAN Assessment of Clinical Effects of Cholesteryl Ester Transfer Protein Inhibition with Evacetrapib in Patients at a High-Risk for Vascular Outcomes - the ACCELERATE Study
    Medical condition: High Risk Vascular Disease (HRVD)
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004866 10067825 Peripheral arterial disease LLT
    18.1 10007541 - Cardiac disorders 10051592 Acute coronary syndrome PT
    18.1 10007541 - Cardiac disorders 10011078 Coronary artery disease PT
    18.1 100000004852 10003602 Atherosclerosis cerebral LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) SK (Prematurely Ended) EE (Prematurely Ended) DE (Prematurely Ended) BE (Prematurely Ended) SE (Prematurely Ended) HU (Prematurely Ended) AT (Completed) ES (Prematurely Ended) LT (Prematurely Ended) DK (Prematurely Ended) IT (Prematurely Ended) CZ (Prematurely Ended) PL (Prematurely Ended) BG (Prematurely Ended) NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2023-000029-10 Sponsor Protocol Number: DESC-HBR Start Date*: 2023-03-24
    Sponsor Name:Azienda Ospedaliera Universitaria Gaetano Martino Messina
    Full Title: De-Escalation of Antiplatelet Therapy to Evaluate Platelet Reactivity and Clinical Outcomes after Coronary Stenting in Patients at High Bleeding Risk and Recent Acute Coronary Syndrome: DESC-HBR trial
    Medical condition: High bleeding risk (HBR) patients with a recent acute coronary syndrome (ACS ) who have undergone percutaneous coronary intervention (PCI) and are on double antiplatelet therapy (DAPT)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10051592 Acute coronary syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-000686-23 Sponsor Protocol Number: RAVE_v1 Start Date*: 2017-03-29
    Sponsor Name:Erasmus MC
    Full Title: The Rotterdam Antiplatelet Therapy in Vascular Patients Study
    Medical condition: myocardial injury in patients undergoing major vascular surgery, leading to (spontaneous) acute coronary syndrome and death through intracoronary plaque damage and subsequent thrombosis after major...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2021-002813-33 Sponsor Protocol Number: ARMYDA-9DAPAtrial Start Date*: 2023-02-21
    Sponsor Name:AZIENDA OSPEDALIERO UNIVERSITARIA MAGGIORE DELLA CARITà DI NOVARA
    Full Title: Early use of dapaglifozin in diabetic patients with acute myocardial infarction and reduced ejection fraction: the randomized ARMYDA-9 DAPA trial
    Medical condition: Patients with type 2 diabetes and ST-elevation myocardial infarction treated with primary primary percutaneous coronary intervention and reduced left ventricle ejection fraction.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10064346 STEMI LLT
    20.0 100000004849 10011949 Decompensation cardiac LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-007290-20 Sponsor Protocol Number: TMC-BIV-08-03 Start Date*: Information not available in EudraCT
    Sponsor Name:The Medicines Company UK Ltd.
    Full Title: European Ambulance Acute Coronary Syndrome Angiox Trial: EUROMAX
    Medical condition: Patients presenting with ST-Segment Elevation Acute Coronary Syndrome (STE-ACS) planned for a primary Percutaneous Coronary Intervention (PCI) management strategy
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10051592 Acute coronary syndrome PT
    14.1 100000004848 10041894 ST segment elevation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) DK (Completed) FR (Completed) NL (Completed) CZ (Completed) ES (Completed) PL (Completed) IT (Completed) SI (Completed)
    Trial results: View results
    EudraCT Number: 2009-013157-15 Sponsor Protocol Number: 1218.74 Start Date*: 2010-10-14
    Sponsor Name:SCS Boehringer Ingelheim Comm.V
    Full Title: A multicentre, international, randomised, parallel group, double blind study to evaluate Cardiovascular safety of linagliptin versus glimepiride in patients with type 2 diabetes mellitus at high ca...
    Medical condition: Patients with documented diagnosis of T2DM with insufficient glycaemic control and at high risk of CV events prior to informed consent can be enrolled in the study.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000072461 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) FR (Completed) DE (Completed) PT (Completed) CZ (Completed) ES (Completed) IE (Completed) FI (Completed) SE (Completed) GB (Completed) SK (Completed) IT (Completed) GR (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2013-005529-22 Sponsor Protocol Number: H-6-2013-011 Start Date*: 2014-03-21
    Sponsor Name:Rigshospitalet
    Full Title: Platelet inhibition in comatose patients receiving oral anti platelet therapy through a naso-gastric tube after undergoing acute percutaneous coronary intervention
    Medical condition: Patients surviving cardiac arrest and undergoing percutaneous coronary intervention
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004849 10067273 Acute transmural myocardial infarction LLT
    16.1 100000004849 10064347 Non ST segment elevation myocardial infarction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-000658-27 Sponsor Protocol Number: D5130C05262 Start Date*: 2006-12-12
    Sponsor Name:AstraZeneca AB
    Full Title: A Randomised, Double-blind, Parallel Group, Phase 3, Efficacy and Safety Study of AZD6140 Compared with Clopidogrel for Prevention of Vascular Events in Patients with Non-ST or ST Elevation Acute C...
    Medical condition: non-ST and ST elevation acute coronary syndromes (ACS)
    Disease: Version SOC Term Classification Code Term Level
    9 10011085 HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) FI (Completed) PT (Completed) HU (Completed) DE (Completed) FR (Completed) SE (Completed) AT (Completed) NL (Completed) DK (Completed) SK (Completed) BE (Completed) CZ (Completed) GR (Completed) IT (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2005-001556-20 Sponsor Protocol Number: SB-480848/026 Start Date*: 2005-11-01
    Sponsor Name:GlaxoSmithKline Research & Development Limited
    Full Title: Integrated Biomarker and Imaging Study – 2 (IBIS-2)
    Medical condition: SB-480848 is under developement as a potential anti-atherosclerosis agent for reduction of major cardiovascular events in high risk patient populations.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) CZ (Completed) DE (Completed) AT (Completed) DK (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2010-018235-17 Sponsor Protocol Number: 0709 Start Date*: 2010-04-16
    Sponsor Name:Rigshospitalet
    Full Title: TAILOR Trombocytes And IndividuaLization of ORal antiplatelet treatment after percutaneous coronary intervention (Trombocytter og individualiseret oral antitrombotisk behandling efter perkutan koro...
    Medical condition: Patientens undergoing elective, subacute or acute percutaneous coronary intervention (PI)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10028601 Myocardial ischemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004090-29 Sponsor Protocol Number: AVD100521 Start Date*: 2005-02-07
    Sponsor Name:GlaxoSmithKline Research & Development Ltd [...]
    1. GlaxoSmithKline Research & Development Ltd
    2. GlaxoSmithKline R&D
    Full Title: A Phase III, 18 Month, Multicenter, Randomized, Double-Blind, Active-Controlled Clinical Trial to Compare Rosiglitazone versus Glipizide on the Progression of Atherosclerosis in Subjects with Type ...
    Medical condition: atherosclerosis in Type 2 Diabetes Mellitus patients with cardiovascular disease
    Disease: Version SOC Term Classification Code Term Level
    7.1 10003601 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DE (Completed) LV (Completed) IT (Completed) CZ (Completed) GR (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2014-000197-19 Sponsor Protocol Number: NCT02032303 Start Date*: 2015-07-23
    Sponsor Name:UMBERTO I - POLICLINICO DI ROMA
    Full Title: Assessment of Coronary Flow Reserve by Doppler Flow WIre in Patients With Acute Coronary Syndrome Undergoing PercuTaneous Coronary Intervention: DiffErences Between the LoAding Dose of Ticagrelor a...
    Medical condition: Patients with acute coronary syndrome
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10028596 Myocardial infarction PT
    20.0 10007541 - Cardiac disorders 10007541 Cardiac disorders SOC
    20.0 10007541 - Cardiac disorders 10002388 Angina unstable PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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