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Clinical trials for Neuropathic pain

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44344   clinical trials with a EudraCT protocol, of which   7373   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    287 result(s) found for: Neuropathic pain. Displaying page 8 of 15.
    EudraCT Number: 2015-001769-14 Sponsor Protocol Number: LACO15 Start Date*: 2017-02-13
    Sponsor Name:Javier E. Morales Sarabia
    Full Title: Analgesic efficacy of intravenous lacosamide administered perioperatively for thoracic surgery with thoracotomy approach.
    Medical condition: Acute postoperative pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-000991-27 Sponsor Protocol Number: 802NP206 Start Date*: 2018-02-27
    Sponsor Name:Biogen Idec Research Limited
    Full Title: A Phase 2 Placebo-Controlled, Double-Blind, Enriched Enrollment Randomized Withdrawal Study to Evaluate the Efficacy and Safety of BIIB074 (Vixotrigine) in Treating Pain Experienced by Subjects Wit...
    Medical condition: Treating Pain Experienced by Subjects With Confirmed Small Fibre Neuropathy That is Idiopathic or Associated With Diabetes Mellitus
    Disease: Version SOC Term Classification Code Term Level
    20.1 10029205 - Nervous system disorders 10073928 Small fibre neuropathy PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) CZ (Prematurely Ended) GR (Completed) HU (Prematurely Ended) ES (Prematurely Ended) DK (Prematurely Ended) BG (Prematurely Ended) NL (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-003655-20 Sponsor Protocol Number: GWPHN0602 Start Date*: 2008-11-21
    Sponsor Name:GW Pharma Ltd
    Full Title: A double blind, randomised, placebo controlled, parallel group study of Sativex® when added to the existing treatment regimen, in the relief of post-herpetic neuralgia.
    Medical condition: Post-herpetic neuralgia symptom relief.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-003787-21 Sponsor Protocol Number: 201781-504 Start Date*: 2007-11-29
    Sponsor Name:Allergan Ltd
    Full Title: A Pilot, Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study with a 4-Week Treatment Period Followed by a 4-week Observation Period and an Optional 4 Month Observation Period of the Sa...
    Medical condition: Postherpetic neuralgia or post-traumatic peripheral neuralgia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-001218-26 Sponsor Protocol Number: TRO19622 CL E Q 1204-1 Start Date*: 2008-06-19
    Sponsor Name:TROPHOS SA
    Full Title: A double blind, placebo controlled study of the effect of 330mg QD of TRO19622 in the treatment of Chemotherapy Induced Peripheral Neuropathy.
    Medical condition: Symptoms of chemotherapy induced peripheral neuropathy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036109 Polyneuropathy due to drugs LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2022-000435-23 Sponsor Protocol Number: ATX01-22-01-CIPN Start Date*: 2022-07-26
    Sponsor Name:AlgoTherapeutix
    Full Title: A multicenter, randomized, double-blind, parallel group, placebo controlled, Phase 2 study to assess the efficacy and safety of ATX01 (topical amitriptyline hydrochloride 10% and 15% w/w) in compar...
    Medical condition: chemotherapy-induced peripheral neuropathy (CIPN)
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004852 10079545 Chemotherapy induced peripheral neuropathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) CZ (Completed) ES (Ongoing) BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-005996-32 Sponsor Protocol Number: LDH0230 Start Date*: 2008-06-25
    Sponsor Name:Luton & Dunstable Hospital NHS Foundation Trust
    Full Title: To determine the pre-emptive effect of Gabapentin on acute and chronic post-operative pain after spinal surgery
    Medical condition: Acute and chronic back pain after surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-000864-41 Sponsor Protocol Number: CHUB-patch-lidocaine Start Date*: 2016-06-02
    Sponsor Name:Centre Hospitalier Universitaire Brugmann
    Full Title: A randomized controlled trial of lidocaine patch for lower limb amputation pain.
    Medical condition: Lower limb amputation pain: phantom limb pain and primary/secondary scar hyperalgesia.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2006-002185-19 Sponsor Protocol Number: C119 Start Date*: 2006-09-06
    Sponsor Name:NeurogesX Incorporated
    Full Title: A MULTICENTER RANDOMIZED, DOUBLE-BLIND, CONTROLLED STUDY OF NGX-4010 FOR THE TREATMENT OF PAINFUL HIV-ASSOCIATED NEUROPATHY
    Medical condition: Treatment of painful HIV-associated neuropathy
    Disease: Version SOC Term Classification Code Term Level
    8.1 10054095 Neuropathic pain PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-000280-16 Sponsor Protocol Number: CEMA401A2201 Start Date*: 2017-05-16
    Sponsor Name:Novartis Pharma AG
    Full Title: A double-blind, placebo-controlled, randomized dose ranging trial to determine the safety and efficacy of three dose levels of EMA401 in reducing 24-hour average pain intensity score in patients wi...
    Medical condition: Post-herpetic neuralgia
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10036376 Post herpetic neuralgia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Prematurely Ended) SK (Prematurely Ended) AT (Prematurely Ended) NO (Prematurely Ended) DK (Prematurely Ended) ES (Prematurely Ended) CZ (Prematurely Ended) HU (Prematurely Ended) FR (Completed) BE (Prematurely Ended) PT (Prematurely Ended) PL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-012586-55 Sponsor Protocol Number: Protocol_DNIC_2009 Start Date*: 2009-08-27
    Sponsor Name:Leiden University Medical Center
    Full Title: Influence of S(+)-ketamine on Diffuse Noxious Inhibitory Control (DNIC) and offset analgesia (OA) in chronic pain patients (neuropathic pain, complex regional pain syndrome type 1, fibromyalgia) an...
    Medical condition: Chronic pain patients: CRPS-1, fibromyalgia and neurptahic pain
    Disease:
    Population Age: Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-010427-12 Sponsor Protocol Number: KF5503/44 Start Date*: 2009-10-14
    Sponsor Name:Grünenthal GmbH
    Full Title: An evaluation of the effectiveness and tolerability of tapentadol hydrochloride prolonged release, and tapentadol hydrochloride immediate release on demand, in subjects with uncontrolled severe chr...
    Medical condition: Low back Pain
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024891 Low back pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) FR (Completed) AT (Completed) DE (Completed) IT (Completed) PL (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2020-001068-27 Sponsor Protocol Number: 2020-001068-27 Start Date*: 2020-12-01
    Sponsor Name:Leiden University Medical Center
    Full Title: Pamidronate for pain in adult chronic nonbacterial osteitis (PAM-CNO): a randomized, double-blind, placebo-controlled trial
    Medical condition: Chronic nonbacterial osteitis (CNO) in adults
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2012-000400-14 Sponsor Protocol Number: ESTEVE-SIGM-204 Start Date*: 2012-06-14
    Sponsor Name:Laboratorios del Dr. Esteve. S.A
    Full Title: An exploratory, randomized, double blind, placebo controlled, parallel groups Phase II clinical trial to evaluate the efficacy and safety of E-52862 (400 mg) by oral route, in patients with painful...
    Medical condition: painful diabetic neuropathy
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10067547 Diabetic peripheral neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) RO (Completed)
    Trial results: View results
    EudraCT Number: 2022-002611-29 Sponsor Protocol Number: 82050 Start Date*: 2023-06-12
    Sponsor Name:Leiden University Medical Center
    Full Title: DEnosumab for the treatment of FIbrous Dysplasia/McCune-Albright Syndrome in adults (DeFiD): a randomized double-blind placebo-controlled trial
    Medical condition: Fibrous Dysplasia/ McCune Albright Syndrome
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-018920-21 Sponsor Protocol Number: ZICBOL2010 Start Date*: 2011-03-23
    Sponsor Name:Landstinget i Östergötland
    Full Title: Evaluation of a Structured Algorithm for Intrathecal Bolus Doses of Ziconotide(Prialt®) - The Swedish Ziconotide Bolus Study
    Medical condition: Chronic pain
    Disease: Version SOC Term Classification Code Term Level
    12.1 10049475 Chronic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2021-000096-36 Sponsor Protocol Number: Botox-01 Start Date*: 2021-06-23
    Sponsor Name:Department of Dermatology and Copenhagen Wound Healing Center, Bispebjerg Hospital
    Full Title: The effect of subcutaneous injection of Botulinum Toxin A on chronic wound pain in lower extremities, a prospective exploratory study
    Medical condition: chronic wound pain and wound healing
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10049542 Wound pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2011-002557-56 Sponsor Protocol Number: ACT11705 Start Date*: 2011-11-24
    Sponsor Name:sanofi-aventis
    Full Title: A randomized, double-blind, parallel-group, placebo-controlled study to assess the clinical benefit of SSR411298 as adjunctive treatment for persistent cancer pain
    Medical condition: cancer pain
    Disease: Version SOC Term Classification Code Term Level
    14.1 10018065 - General disorders and administration site conditions 10069398 Breakthrough cancer pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Prematurely Ended) CZ (Prematurely Ended) HU (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2021-001629-38 Sponsor Protocol Number: KLG0121 Start Date*: 2022-02-21
    Sponsor Name:Dompè Farmaceutici S.p.A.
    Full Title: A phase 2, multicenter, randomized, double blind, active controlled, parallel group study assessing the analgesic effect and safety of two doses of DFL24412 in patients with chronic low back pain c...
    Medical condition: Chronic Low Back Pain
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004859 10052430 Chronic lumbago LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2015-001136-37 Sponsor Protocol Number: CR4056-2-01 Start Date*: 2015-08-19
    Sponsor Name:Rottapharm Biotech S.r.l.
    Full Title: A randomized, double-blind, parallel group, placebo-controlled study to evaluate the efficacy, safety and tolerability of CR4056 administered for 2 weeks in patients with osteoarthritis of the knee...
    Medical condition: Moderate to severe chronic pain due to knee osteoarthritis with or without neuropathic component.
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) PL (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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