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Clinical trials for Accident prevention

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44258   clinical trials with a EudraCT protocol, of which   7344   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    44 result(s) found for: Accident prevention. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2005-003700-10 Sponsor Protocol Number: CL3-18886-012 Start Date*: 2006-01-27
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Prevention of cerebrovascular and cardiovascular Events of ischaemic origin with teRutroban in patients with a history oF ischaemic strOke or tRansient ischaeMic attack. The PERFORM Study. An inter...
    Medical condition: Ischaemic stroke or transient ischaemic attack
    Disease: Version SOC Term Classification Code Term Level
    7.0 10008190 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) AT (Prematurely Ended) FI (Completed) ES (Completed) GB (Completed) SE (Prematurely Ended) HU (Completed) CZ (Prematurely Ended) SI (Prematurely Ended) LT (Prematurely Ended) IT (Prematurely Ended) PT (Prematurely Ended) SK (Completed) DE (Completed) IE (Prematurely Ended) GR (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-003179-32 Sponsor Protocol Number: ToL54304 Start Date*: 2016-02-03
    Sponsor Name:University Medical Center Utrecht
    Full Title: PREvention of Complications to Improve Outcome in elderly patients with acute Stroke. A randomised, open, phase III, clinical trial with blinded outcome assessment.
    Medical condition: Stroke (ischaemic stroke or intracerebral hemorrhage)
    Disease: Version SOC Term Classification Code Term Level
    22.1 10029205 - Nervous system disorders 10061256 Ischaemic stroke PT
    21.1 10029205 - Nervous system disorders 10022754 Intracerebral hemorrhage LLT
    22.1 10029205 - Nervous system disorders 10042244 Stroke LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: NL (Completed) HU (Completed) GR (Completed) IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-003519-23 Sponsor Protocol Number: D513BC00001 Start Date*: 2014-02-05
    Sponsor Name:AstraZeneca AB
    Full Title: A Multinational, Randomised, Double-Blind, Placebo-Controlled Trial to Evaluate the Effect of Ticagrelor twice daily on the Incidence of Cardiovascular Death, Myocardial Infarction or Stroke in Pat...
    Medical condition: major cardiovascular events in type 2 diabetes mellitus patients
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004852 10042244 Stroke LLT
    19.1 10007541 - Cardiac disorders 10028596 Myocardial infarction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) CZ (Completed) SK (Completed) SE (Completed) NL (Completed) DE (Completed) IT (Completed) GB (Completed) ES (Completed) NO (Completed) AT (Completed) DK (Completed) BE (Completed) FI (Completed) BG (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2011-000110-19 Sponsor Protocol Number: P060406 Start Date*: 2012-01-10
    Sponsor Name:Assistance Publique – Hôpitaux de Paris (AP-HP)
    Full Title: Closure of patent foramen ovale or anticoagulants versus antiplatelet therapy to prevent stroke recurrence
    Medical condition: The study compares different strategies for secondary stroke (or retinal ischaemia) prevention in patients with patent foramen ovale. The three treatment arms comprise: 1. Endovascular patent f...
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004865 10036654 Prevention LLT
    19.0 100000004850 10016982 Foramen ovale patent LLT
    19.0 100000004852 10042244 Stroke LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-001953-33 Sponsor Protocol Number: PrevSVD-2015 Start Date*: 2015-10-09
    Sponsor Name:University of Edinburgh [...]
    1. University of Edinburgh
    2. NHS Lothian
    Full Title: Preventing cognitive decline and dementia from cerebral small vessel disease
    Medical condition: Lacunar (small vessel) ischaemic stroke
    Disease: Version SOC Term Classification Code Term Level
    19.0 10029205 - Nervous system disorders 10023987 Late effects of cerebrovascular disease LLT
    19.0 10029205 - Nervous system disorders 10042244 Stroke LLT
    19.0 10029205 - Nervous system disorders 10061256 Ischaemic stroke PT
    19.0 10029205 - Nervous system disorders 10068644 Brain stem stroke PT
    19.0 10029205 - Nervous system disorders 10071043 Basal ganglia stroke PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-002277-35 Sponsor Protocol Number: AC16093 Start Date*: 2017-06-01
    Sponsor Name:University of Edinburgh [...]
    1. University of Edinburgh
    2. NHS Lothian
    Full Title: LACunar Intervention (LACI-2) Trial-2: Assessment of safety and efficacy of cilostazol and isosorbide mononitrate to prevent recurrent lacunar stroke and progression of cerebral small vessel disease.
    Medical condition: lacunar (small vessel) ischaemic stroke
    Disease: Version SOC Term Classification Code Term Level
    20.1 10029205 - Nervous system disorders 10071043 Basal ganglia stroke PT
    20.0 10029205 - Nervous system disorders 10068644 Brain stem stroke PT
    20.0 10029205 - Nervous system disorders 10023987 Late effects of cerebrovascular disease LLT
    20.0 10029205 - Nervous system disorders 10061256 Ischaemic stroke PT
    20.0 10029205 - Nervous system disorders 10042244 Stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2019-001336-62 Sponsor Protocol Number: 2019-ASPIREAF Start Date*: 2020-04-01
    Sponsor Name:Hamilton Health Sciences Corporation
    Full Title: Anticoagulation for Stroke Prevention In patients with Recent Episodes of perioperative Atrial Fibrillation after noncardiac surgery - The ASPIRE-AF trial
    Medical condition: Perioperative atrial fibrillation after noncardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    22.1 100000004852 10042244 Stroke LLT
    20.0 100000004866 10005103 Bleeding LLT
    20.0 100000004849 10003663 Atrial flutter/ fibrillation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned) ES (Ongoing) IT (Trial now transitioned) NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2005-001256-20 Sponsor Protocol Number: ITI 101724 Start Date*: 2005-11-03
    Sponsor Name:GlaxoSmithKline Research and Development Ltd.
    Full Title: A randomized, double blind, double dummy, parallel group, placebo controlled study to evaluate the pharmacodynamic and pharmacokinetic response and safety and tolerability of SB424323 (250 mg, 375 ...
    Medical condition: Non-valvular Atrial Fibrillation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) GB (Completed) EE (Completed) HU (Completed) DK (Completed) LV (Completed) IT (Completed) DE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2007-001557-26 Sponsor Protocol Number: CV185-048 Start Date*: 2008-04-29
    Sponsor Name:Bristol Myers Squibb International Corporation
    Full Title: Apixaban Versus Acetylsalicyclic Acid (ASA) to Prevent Stroke in Atrial Fibrillation Patients Who Have Failed or are Unsuitable for Vitamin K Antagonist Treatment: A Randomized Double Blind Trial ...
    Medical condition: Patients with atrial fibrillation and at least one additional risk factor for stroke who have failed or are unsuitable for vitamin K antagonist therapy.
    Disease: Version SOC Term Classification Code Term Level
    13.1 10029205 - Nervous system disorders 10042244 Stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) FR (Completed) SE (Completed) BE (Completed) DE (Completed) FI (Completed) ES (Completed) DK (Completed) CZ (Completed) AT (Completed) GR (Completed) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2009-010761-22 Sponsor Protocol Number: 82/09 Start Date*: 2009-04-25
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: ECG changes and C-protein level variations during and after treatment with atorvastatin at different dosages in the secondary prevention of stroke.
    Medical condition: Stroke
    Disease: Version SOC Term Classification Code Term Level
    9.1 10055221 Ischemic stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-004761-34 Sponsor Protocol Number: 150-CL-012 Start Date*: 2007-04-19
    Sponsor Name:Astellas US Pharma US Inc.(APUS)
    Full Title: A Phase 2, Double-Blind, Double-Dummy, Randomized, Parallel Group Study to Evaluate the Safety, Tolerability and Pharmacodynamics of YM150 in Subjects with Non-Valvular Atrial Fibrillation.
    Medical condition: Prevention of stroke on patients with Non-Valvular Atrial Fibrillation
    Disease: Version SOC Term Classification Code Term Level
    8.1 10049165 Cerebrovascular accident prophylaxis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Prematurely Ended) DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-003895-38 Sponsor Protocol Number: D5134C00001 Start Date*: 2014-02-11
    Sponsor Name:AstraZeneca AB
    Full Title: A randomised, double-blind, multinational study to prevent major vascular events with Ticagrelor compared to Aspirin(ASA) in patients with acute ischaemic stroke or Transient Ischemic Attack (TIA)....
    Medical condition: ischaemic stroke
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004852 10055221 Ischemic stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) SK (Completed) BE (Completed) SE (Completed) DE (Completed) IT (Completed) ES (Completed) BG (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2017-000075-85 Sponsor Protocol Number: I-StrokeII2016 Start Date*: 2018-06-19
    Sponsor Name:Karolinska Institutet
    Full Title: A phase 3, randomised, double-blind, placebo-controlled, parallel-arm efficacy trial of Imatinib in acute ischaemic stroke
    Medical condition: Patients with acute ischaemic stroke and an imaging scan excluding any intracranial haemorrhage
    Disease: Version SOC Term Classification Code Term Level
    22.1 10029205 - Nervous system disorders 10061256 Ischaemic stroke PT
    22.1 10029205 - Nervous system disorders 10055221 Ischemic stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-001067-27 Sponsor Protocol Number: 20604 Start Date*: 2022-11-10
    Sponsor Name:Bayer AG
    Full Title: A multicenter, international, randomized, placebo controlled, double-blind, parallel group and event driven Phase 3 study of the oral FXIa inhibitor asundexian (BAY 2433334) for the prevention of i...
    Medical condition: Prevention of ischemic stroke in patients post acute non-cardioembolic ischemic stroke or high-risk transient ischemic attack
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10049165 Cerebrovascular accident prophylaxis PT
    22.1 100000004852 10055221 Ischemic stroke LLT
    20.1 100000004852 10072760 Transient ischemic attack LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned) FI (Trial now transitioned) SE (Trial now transitioned) NO (Trial now transitioned) LT (Trial now transitioned) HU (Trial now transitioned) ES (Ongoing) AT (Trial now transitioned) FR (Trial now transitioned) IT (Trial now transitioned) BE (Trial now transitioned) GR (Ongoing) CZ (Trial now transitioned) NL (Trial now transitioned) PL (Trial now transitioned) LV (Trial now transitioned) PT (Trial now transitioned) BG (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-003406-14 Sponsor Protocol Number: UHNM1219 Start Date*: 2017-09-26
    Sponsor Name:University Hospital of North Midlands NHS Trust
    Full Title: The Metoclopramoide and selective oral decontamination for Avoiding Pneumonia after Stroke (MAPS-2) Trial: a 2x2 double-blind, randomized controlled trial of metoclopramide and selective oral decon...
    Medical condition: Stroke We are testing two differnt intervetnions which could prevent pneumonia in stroke patietns. Prevention pneumonia could potentiallly speed up recovery and improve survival.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10035669 Pneumonia aspiration PT
    20.0 10029205 - Nervous system disorders 10061256 Ischaemic stroke PT
    20.1 10029205 - Nervous system disorders 10019016 Haemorrhagic stroke PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-004232-37 Sponsor Protocol Number: D5134C00003 Start Date*: 2017-12-05
    Sponsor Name:AstraZeneca AB
    Full Title: A Randomised, Double-Blind, Placebo-Controlled, International, Multicentre, Phase III Study to Investigate the Efficacy and Safety of Ticagrelor and ASA Compared with ASA in the Prevention of Strok...
    Medical condition: Ischaemic stroke, transient ischaemic attack
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10061256 Ischaemic stroke PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) CZ (Completed) HU (Completed) BG (Completed) FR (Completed) DE (Completed) ES (Completed) BE (Completed) PL (Completed) SK (Completed) IT (Completed) RO (Completed)
    Trial results: View results
    EudraCT Number: 2015-003959-22 Sponsor Protocol Number: CV006-004 Start Date*: 2016-09-06
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: A Phase 2, Placebo Controlled, Randomized, Double-Blind, Parallel-Arm Study to Evaluate Efficacy and Safety of BMS-986141 For the Prevention of Recurrent Brain Infarction in Subjects receiving acet...
    Medical condition: Recurrent Brain Infarction in Subjects receiving acetylsalicyl acid (ASA) following Acute Ischemic Stroke or Transient Ischemic Attack
    Disease: Version SOC Term Classification Code Term Level
    19.0 10029205 - Nervous system disorders 10061256 Ischaemic stroke PT
    19.0 10029205 - Nervous system disorders 10044390 Transient ischaemic attack PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-006206-24 Sponsor Protocol Number: Aivoverenvuotopotilaan tromboosipro Start Date*: 2008-12-17
    Sponsor Name:Hillbom Matti OYS/neurologian klinikka
    Full Title: A blind randomized trial to compare the efficacy of intermittent pneumatic compression (IPC) with and without early anticoagulant treatment for prevention of venous thromboembolism (VTE) in patient...
    Medical condition: Spontaani aivoverenvuoto
    Disease: Version SOC Term Classification Code Term Level
    9.1 10022754 Intracerebral hemorrhage LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-004746-10 Sponsor Protocol Number: NTA1702 Start Date*: 2021-01-27
    Sponsor Name:The Florey Institute of Neuroscience and Mental Health
    Full Title: STOP-MSU – Stopping haemorrhage with Tranexamic acid for hyperacute Onset Presentation including Mobile Stroke Units
    Medical condition: Intracerebral Haemorrhage
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004852 10022751 Intracerebral bleed LLT
    21.1 100000004852 10068342 Intracerebral haematoma LLT
    21.1 100000004852 10022754 Intracerebral hemorrhage LLT
    21.1 100000004852 10022753 Intracerebral haemorrhage LLT
    21.1 100000004852 10068344 Intracerebral hematoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2006-004870-28 Sponsor Protocol Number: 9.182 Start Date*: 2008-05-13
    Sponsor Name:Boehringer Ingelheim Pharma GmbH & Co. KG
    Full Title: Prospective, randomized, national, multi-centre, open-label, blinded endpoint study to compare Aggrenox® b.i.d. (200 mg dipyridamole MR + 25 mg acetylsalicylic acid) when started within 24 hours of...
    Medical condition: Ischaemic stroke
    Disease: Version SOC Term Classification Code Term Level
    8.1 10023027 Ischaemic stroke NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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