Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Enalapril

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    55 result(s) found for: Enalapril. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2008-004104-31 Sponsor Protocol Number: CSPP100F2301 Start Date*: 2009-03-13
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A multicenter, randomized, double-blind, parallel group, active-controlled study to evaluate the efficacy and safety of both aliskiren monotherapy and aliskiren/enalapril combination therapy compar...
    Medical condition: Chronic heart failure (NYHA Class II - IV)
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004849 10008908 Chronic heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) DE (Completed) SK (Completed) NL (Completed) FI (Completed) SE (Completed) DK (Completed) LT (Completed) BE (Completed) PT (Completed) IT (Completed) IE (Completed) ES (Completed) CZ (Completed) PL (Completed) FR (Completed) LV (Completed) GB (Completed) EE (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2016-003085-32 Sponsor Protocol Number: CLCZ696B3301 Start Date*: 2016-11-14
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A multi-center, prospective, randomized, double-blind study to assess the impact of sacubitril/valsartan vs. enalapril on daily physical activity using a wrist worn actigraphy device in adult chron...
    Medical condition: Heart Failure with reduced ejection fraction (HFrEF)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) LT (Completed) SE (Completed) EE (Completed) DK (Completed) LV (Completed) BE (Completed) ES (Completed) FI (Completed) FR (Completed) BG (Completed) NL (Completed) IS (Completed) GR (Completed) CZ (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-004207-22 Sponsor Protocol Number: CLCZ696B2319 Start Date*: 2017-04-06
    Sponsor Name:Novartis Pharma Services AG
    Full Title: Multicenter, open-label, study to evaluate safety, tolerability, pharmacokinetics and, pharmacodynamics of LCZ696 followed by a 52-week randomized, double-blind, parallel group, active-controlled s...
    Medical condition: Pediatric heart failure 1 month to <18 years old
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10019279 Heart failure LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed) FI (Completed) NL (Ongoing) SE (Completed) NO (Completed) ES (Completed) GB (GB - no longer in EU/EEA) CZ (Completed) IT (Completed) FR (Completed) BG (Completed) PL (Completed) HU (Completed) HR (Completed) AT (Completed) PT (Completed) RO (Completed)
    Trial results: View results
    EudraCT Number: 2009-015834-31 Sponsor Protocol Number: CLCZ696B2314 Start Date*: 2010-01-01
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A multicenter, randomized, double-blind, parallel group, active-controlled study to evaluate the efficacy and safety of LCZ696 compared to enalapril on morbidity and mortality in patients with chro...
    Medical condition: Chronic Heart Failure
    Disease: Version SOC Term Classification Code Term Level
    15.1 100000004849 10008502 CHF LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PT (Completed) IS (Completed) GB (Completed) ES (Prematurely Ended) DE (Completed) HU (Completed) NL (Prematurely Ended) SE (Completed) IT (Prematurely Ended) RO (Completed) SK (Completed) FI (Completed) FR (Completed) DK (Completed) BE (Completed) CZ (Completed) LT (Completed) EE (Completed) LV (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2006-005408-14 Sponsor Protocol Number: CVAL489K2302-E1 Start Date*: 2007-04-23
    Sponsor Name:Novartis Pharma Services AG
    Full Title: An extension to study protocol CVAL489K2302 to evaluate the long term safety, tolerability and efficacy of valsartan children 6 to 17 years of age with hypertension, versus enalapril treatment for ...
    Medical condition: Hypertension
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed) DE (Prematurely Ended) GB (Prematurely Ended) HU (Prematurely Ended) FR (Completed) SE (Prematurely Ended) CZ (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-001094-16 Sponsor Protocol Number: PROACT Start Date*: 2017-08-08
    Sponsor Name:South Tees NHS Foundation Trust
    Full Title: Preventing cardiac damage in patients treated for breast cancer and lymphoma: a phase 3 Randomised, Open label, blinded endpoint, trial of enalapril to prevent Anthracycline-induced CardioToxicity ...
    Medical condition: Prevention of cardiotoxicity
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10048610 Cardiotoxicity PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2015-002396-18 Sponsor Protocol Number: 2015-602295-02 Start Date*: 2015-11-30
    Sponsor Name:Ethicare GmbH
    Full Title: ORODISPERSIBLE MINITABLETS OF ENALAPRIL IN YOUNG CHILDREN WITH HEART FAILURE DUE TO CONGENITAL HEART DISEASE
    Medical condition: Heart Failure due to Congenital Heart Disease
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004850 10010495 Congenital heart disease NOS LLT
    Population Age: Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: HU (Completed) GB (Prematurely Ended) NL (Ongoing) AT (Completed) DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-004632-35 Sponsor Protocol Number: CLCZ696BDE01 Start Date*: 2016-05-04
    Sponsor Name:Novartis Pharma GmbH
    Full Title: A randomized, double-blind, active-controlled study to assess the effect of LCZ696 compared with enalapril to improve exercise capacity in patients with heart failure with reduced ejection fraction...
    Medical condition: chronic heart failure and reduced ejection fraction
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10008502 CHF LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-015988-13 Sponsor Protocol Number: REC15/2375-IT-CL0336 Start Date*: Information not available in EudraCT
    Sponsor Name:Recordati S.p.A.,
    Full Title: An international multicentre, randomized, parallel group, double-blind trial to evaluate different dose combinations of lercanidipine and enalapril in comparison with each component administered al...
    Medical condition: Essential hypertension
    Disease: Version SOC Term Classification Code Term Level
    12.0 10015488 Essential hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Completed) FR (Completed) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2015-002397-21 Sponsor Protocol Number: 2015-602295-03 Start Date*: 2015-11-30
    Sponsor Name:Ethicare GmbH
    Full Title: FOLLOW-UP SAFETY TRIAL IN CHILDREN WITH CHRONIC HEART FAILURE THERAPY RECEIVING ORODISPERSIBLE MINITABLETS OF ENALAPRIL
    Medical condition: Heart Failure due to Dilated Cardiomyopathy and Congenital Heart Disease
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004850 10010495 Congenital heart disease NOS LLT
    18.1 100000004849 10056419 Dilated cardiomyopathy LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: HU (Completed) GB (GB - no longer in EU/EEA) NL (Ongoing) AT (Completed) DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-005260-88 Sponsor Protocol Number: CVAL489K2302 Start Date*: 2007-04-23
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A multicenter, randomized, double-blind, parallel-group, evaluation of 12 weeks of valsartan compared to enalapril on sitting systolic blood pressure in children 6 to 17 years of age with hyperten...
    Medical condition: Hypertension
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed) FR (Completed) DE (Completed) HU (Completed) SE (Completed) CZ (Prematurely Ended) PL (Completed) IT (Completed) SK (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-017029-20 Sponsor Protocol Number: CSPP100A2365E1 Start Date*: 2010-11-19
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A multicenter, double-blind, randomized, 52 week extension study to evaluate the long term safety, tolerability and efficacy of aliskiren compared to enalapril in pediatric hypertensive patients 6-...
    Medical condition: Hypertension
    Disease: Version SOC Term Classification Code Term Level
    17.0 10047065 - Vascular disorders 10020772 Hypertension PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: SK (Completed) DE (Completed) HU (Completed) BE (Completed) FR (Ongoing) PL (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2015-002335-17 Sponsor Protocol Number: 2015-602295-01 Start Date*: 2015-11-30
    Sponsor Name:Ethicare GmbH
    Full Title: ORODISPERSIBLE MINITABLETS OF ENALAPRIL IN CHILDREN WITH HEART FAILURE DUE TO DILATED CARDIOMYOPATHY
    Medical condition: Heart Failure due to Dilated Cardiomyopathy
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004849 10056419 Dilated cardiomyopathy LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: HU (Completed) NL (Completed) GB (GB - no longer in EU/EEA) AT (Completed) DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-001394-25 Sponsor Protocol Number: REDLEVEL Start Date*: 2013-08-01
    Sponsor Name:Universidad de Salamanca
    Full Title: Prospective, randomized, open-label, blinded-endpoint, paralell groups, multicentric clinical trial to compare the efficacy of administration of enalapril 20 mg + lercanidipine 10 mg versus enalapr...
    Medical condition: Chronic kidney disease and arterial hypertension with proteinuria.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038359 - Renal and urinary disorders 10037032 Proteinuria PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-000220-33 Sponsor Protocol Number: CLCZ696BDE03 Start Date*: 2019-02-04
    Sponsor Name:Novartis Pharma GmbH
    Full Title: A randomized, double-blind, active-controlled study to assess the effect of sacubitril/valsartan compared with enalapril to improve erectile function in patients with heart failure with reduced eje...
    Medical condition: Patients with heart failure with reduced ejection fraction (HFrEF) and erectile dysfunction (ED)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10008502 CHF LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-001568-29 Sponsor Protocol Number: ras-blok Start Date*: 2005-06-22
    Sponsor Name:Dept. of Nephrology
    Full Title: Pulsbølgehastighed og pulsbølgemorfologi hos patienter med kronisk nyreinsufficiens: Effekten af blokade af renin-angiotensinsystemet.
    Medical condition: Kronisk nyreinsufficiens
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-003410-28 Sponsor Protocol Number: CLCZ696D2302 Start Date*: 2017-06-05
    Sponsor Name:Novartis Pharma AG
    Full Title: A 24-week, randomized, double-blind, multi-center, parallel group, active controlled study to evaluate the effect of LCZ696 on NT-proBNP, exercise capacity, symptoms and safety compared to individu...
    Medical condition: Heart Failure with preserved Ejection Fraction (HFpEF)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PT (Completed) HU (Completed) LV (Completed) ES (Completed) FR (Completed) SK (Completed) CZ (Completed) GB (Completed) LT (Completed) AT (Completed) DK (Completed) BG (Completed) BE (Completed) NL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2017-003180-35 Sponsor Protocol Number: R04725 Start Date*: 2018-06-15
    Sponsor Name:Manchester University NHS Foundation Trust
    Full Title: Feasibility study on the effects of postnatal enalapril on maternal cardiovascular function following preterm pre-eclampsia
    Medical condition: Postnatal (PN) cardiovascular dysfunction following preterm pre-eclampsia (pPE)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10036585 - Pregnancy, puerperium and perinatal conditions 10036485 Pre-eclampsia PT
    20.0 10036585 - Pregnancy, puerperium and perinatal conditions 10036485 Pre-eclampsia PT
    20.0 10036585 - Pregnancy, puerperium and perinatal conditions 10040444 Severe pre-eclampsia LLT
    20.1 100000004849 10007648 Cardiovascular disease, unspecified LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2005-002161-36 Sponsor Protocol Number: PM-C-0024 Start Date*: 2006-02-08
    Sponsor Name:Sanofi-Aventis Groupe
    Full Title: Randomized comparison of a two-month regimen of irbesartan versus enalapril on cardiovascular markers in patients with acute coronary syndrome without ST segment elevation.
    Medical condition: Acute coronary syndrome
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) HU (Completed) ES (Completed) IT (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-006604-38 Sponsor Protocol Number: OVERCOME Start Date*: 2008-02-22
    Sponsor Name:HOSPITAL CLINIC
    Full Title: Prevención de la disfunción ventricular con enalapril y carvedilol en pacientes sometidos a quimioterapia intensiva para el tratamiento de hemopatías malignas. Prevention of ventricular dysfunctio...
    Medical condition: Disfunción ventricular post quimioterapia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10059056 Ventricular dysfunction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    1  2  3  Next»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Fri May 02 18:47:56 CEST 2025 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA