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Clinical trials for Modifications

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44294   clinical trials with a EudraCT protocol, of which   7351   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    343 result(s) found for: Modifications. Displaying page 1 of 18.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2009-012124-85 Sponsor Protocol Number: 0816302 Start Date*: 2009-07-27
    Sponsor Name:CHU de Toulouse
    Full Title: Etude exploratoire de l’effet d’un traitement par acide nicotinique sur l’inflammation du tissu adipeux sous cutané
    Medical condition: processus de l'inflammation du tissu adipeux et des mécanismes de l'insulinorésistance
    Disease: Version SOC Term Classification Code Term Level
    12.0 10029883 Obesity LLT
    Population Age: Adults Gender: Male
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-000908-17 Sponsor Protocol Number: Siena Eye Cross Linking 2004 Start Date*: 2007-01-11
    Sponsor Name:AZIENDA OSPEDALIERA SENESE
    Full Title: Medical therapy of keratoconus with Riboflavin/Ultraviolet-A collagen Cross-Linking and investigation of the corneal stromal and Keratocytes modifications apoptosis and stromal repopulation with ...
    Medical condition: Patients affected by keratoconus worsening
    Disease: Version SOC Term Classification Code Term Level
    6.1 10023353 PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004762-23 Sponsor Protocol Number: P/2014/237 Start Date*: 2015-03-26
    Sponsor Name:CHRU Besançon
    Full Title: NO
    Medical condition: sujets à l'attachement insécure
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-006256-22 Sponsor Protocol Number: 0701104 Start Date*: 2008-11-21
    Sponsor Name:CHU Saint-Etienne
    Full Title: Evaluation by high resolution micro computerized tomography of bone microarchitecture changes in patients with rheumatoid arthritis under anti-TNF therapy.
    Medical condition: rheumatoid arthritis requiring anti-TNF alpha treatment
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039075 Rheumatoid arthritis and associated conditions HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-016734-26 Sponsor Protocol Number: CTBM100C2303E2 Start Date*: 2010-01-08
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A Phase III Open-Label Extension Study to Assess the Safety and Efficacy of Tobramycin Inhalation Powder after Manufacturing Process Modifications (TIPnew) in Cystic Fibrosis (CF) Patients Who succ...
    Medical condition: Pseudomonas aeruginosa infection in cystic fibrosis patients
    Disease: Version SOC Term Classification Code Term Level
    12.0 10021860 Infection pseudomonas aeruginosa LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: EE (Completed) LV (Completed) LT (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2008-004764-39 Sponsor Protocol Number: CTBM100C2303E1 Start Date*: 2009-09-07
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A Phase III Open-Label Extension Study to Assess the Safety and Efficacy of Tobramycin Inhalation Powder after Manufacturing Process Modifications (TIPnew) in Cystic Fibrosis (CF) Subjects Who Comp...
    Medical condition: Pseudomonas aeruginosa infection in cystic fibrosis patients
    Disease: Version SOC Term Classification Code Term Level
    13.1 10021881 - Infections and infestations 10021860 Infection pseudomonas aeruginosa LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: LT (Completed) LV (Completed) EE (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2007-003277-19 Sponsor Protocol Number: nd Start Date*: 2007-09-03
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: modifications on the pain-threshold in labour and the effects of the epidural analgesia and S-Ketamina on the pai-threshold
    Medical condition: pain-threshold
    Disease: Version SOC Term Classification Code Term Level
    6.1 10029772 HLT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-003022-40 Sponsor Protocol Number: UKM14_0008 Start Date*: 2015-03-19
    Sponsor Name:Universitätsklinikum Münster
    Full Title: Comparison of the bacterial microbiota in the skin and gut of psoriasis patients before and after sytemic treatment with adalimumab and ustekinumab or cyclosporin
    Medical condition: Psoriasis
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004858 10050576 Psoriasis vulgaris LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-002318-22 Sponsor Protocol Number: CTBM100C2303 Start Date*: 2009-09-07
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Multi-Center Phase III Study in Cystic Fibrosis (CF) Subjects to Assess Efficacy, Safety and Pharmacokinetics of Tobramycin Inhalation Powder from a ...
    Medical condition: Pseudomonas aeruginosa infection in cystic fibrosis patients
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021860 Infection pseudomonas aeruginosa LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: LT (Completed) LV (Completed) EE (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2008-001495-69 Sponsor Protocol Number: 2008/0801 Start Date*: 2008-07-11
    Sponsor Name:Centre Hospitalier Régional et Universitaire de Lille
    Full Title: Réversibilité sous Tiotropium (SPIRIVA®) chez les patients BPCO : paramètres EFR, dyspnée et TDM
    Medical condition: Traitement bronchodilatateur continu destiné à soulager les symptômes des patients présentant une bronchopneumopathie chronique obstructive (BPCO).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-000120-40 Sponsor Protocol Number: 2006/0606 Start Date*: 2007-06-07
    Sponsor Name:Centre Hospitalier Régional et Universitaire
    Full Title: Etude contrôlée comparative en double aveugle de l'effet d'un traitement par le fénofibrate sur l'expression des génes de l'homéostasie du cholestérol, de l'inflammation et de la prolifération cell...
    Medical condition: Patients présentant des lésions athérosclérosiques carotidiennes asymptomatiques diabétiques ou non diabétiques sous statines .
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-003781-17 Sponsor Protocol Number: CCM S78/407 Start Date*: 2007-07-16
    Sponsor Name:FONDAZIONE MONZINO CENTRO CARDIOLOGICO
    Full Title: COMPARED EFFECTS OF THREE DIFFERENT BETA BLOCKERS (CARVEDILOL, BISOPROLOL AND NEBIVOLOL) ON EXERCISE CAPACITY, PULMONARY FUNCTION AND RESPONSE TO HYPOXIA IN CHRONIC HEART FAILURE
    Medical condition: chronic heart failure
    Disease: Version SOC Term Classification Code Term Level
    6.1 10007558 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-003673-18 Sponsor Protocol Number: 1062016 Start Date*: Information not available in EudraCT
    Sponsor Name:UZ Brussel
    Full Title: Can we with vitamin D3, improve the innate immune system?
    Medical condition: Immunological problems such as hypogammaglobulinemia with clinical recurrent infections such as sinusitis , pneumonia , otitis , skin infections and gastrointestinal infections.
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-019821-32 Sponsor Protocol Number: 20090508 Start Date*: 2010-11-04
    Sponsor Name:Amgen Inc.
    Full Title: A Phase 3, Randomized, Double-Blind Trial of Weekly Paclitaxel Plus AMG 386 or Placebo in Women With Recurrent Partially Platinum Sensitive or Resistant Epithelial Ovarian, Primary Peritoneal or Fa...
    Medical condition: Recurrent partially platinum sensitive or resistant epithelial ovarian, primary peritoneal or fallopian tube cancers
    Disease: Version SOC Term Classification Code Term Level
    12.1 10066697 Ovarian cancer recurrent LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: FR (Completed) ES (Completed) PT (Completed) CZ (Prematurely Ended) SI (Completed) GR (Completed) SE (Completed) LV (Completed) EE (Completed) IT (Completed) BG (Completed) GB (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2021-002478-20 Sponsor Protocol Number: PRECISESTUDY Start Date*: 2022-03-31
    Sponsor Name:AZIENDA OSPEDALIERO UNIVERSITARIA DI FERRARA
    Full Title: IDENTIFICATION OF SYNOVIAL BIOMARKERS OF RESPONSE TO IXEKIZUMAB IN REFRACTORY PSORIATIC ARTHRITIS: THE PRECISE STUDY.
    Medical condition: PSORIATIC ARTHRITIS
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004859 10037160 Psoriatic arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-002207-15 Sponsor Protocol Number: Cardiorete Start Date*: 2011-12-27
    Sponsor Name:FONDAZIONE DEL PIEMONTE PER L'ONCOLOGIA IRCC DI CANDIOLO
    Full Title: A prospective study with beta-blockers and ACE-inhibitors in patients operable breast cancer experiencing mild cardiac toxicity during treatment with anthracycline and/or trastuzumab
    Medical condition: patients experiencing mild cardiotoxicity during treatment with anthracycline and/or trastuzumab for operable breast cancer
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-003230-22 Sponsor Protocol Number: CICL670AIT07 Start Date*: 2008-11-04
    Sponsor Name:NOVARTIS FARMA
    Full Title: Multicenter, open label, prospective study to evaluate the efficacy and safety of deferasirox 30 mg/kg/day for 52 weeks, in transfusion-dependent β-thalassemic patients with cardiac MRI ...
    Medical condition: cardiac iron overload
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019024 Haemosiderosis LLT
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2020-000043-31 Sponsor Protocol Number: 383 Start Date*: 2020-03-26
    Sponsor Name:Groupe Hospitalier Paris Saint-Joseph
    Full Title: Efficacy and tolerance of Liraglutide for weight loss in obese type 2 diabetic hemodialysis patients
    Medical condition: obese type 2 diabetic hemodialysis patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-001772-22 Sponsor Protocol Number: 96HCL15_0122 Start Date*: 2016-01-25
    Sponsor Name:Hospices Civils de Lyon
    Full Title: Mesures des modifications hémodynamiques, fonctionnelles et métaboliques rénales par TEP et BOLD- IRM en lien avec la modification des apports en AGE dans l’alimentation, ou avec sevelamer. ETUDE A...
    Medical condition: Volontaires sains
    Disease: Version SOC Term Classification Code Term Level
    18.1 10022891 - Investigations 10058910 General physical condition normal PT
    Population Age: Adults Gender: Male
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-003359-39 Sponsor Protocol Number: ZEST Start Date*: 2014-01-14
    Sponsor Name:Fundació Clínic per a la Recerca Biomèdica
    Full Title: Bisphosphonate Therapy with Zoledronic acid or Tenofovir Switching to Improve Low Bone Mineral Density in HIV-Infected Adults
    Medical condition: low bone mineral density - HIV
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004862 10068341 HIV-1 infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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