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Clinical trials for Nitrates

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    30 result(s) found for: Nitrates. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2013-004316-22 Sponsor Protocol Number: Nitrate001 Start Date*: 2014-04-17
    Sponsor Name:
    Full Title: INFLUENCE OF NITRATES ON BONE REMODELLING AND ENDOTHELIAL FUNCTION IN PATIENTS WITH TYPE 2 DIABETES MELLITUS
    Medical condition: ENDOTHELIAL DYSFUNCTION AND BONE REMODELLING
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004848 10067225 Biochemical markers of bone metabolism HLT
    16.1 10047065 - Vascular disorders 10048554 Endothelial dysfunction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-004171-37 Sponsor Protocol Number: CH/2005/1944 Start Date*: 2006-08-02
    Sponsor Name:United Bristol Healthcare Trust
    Full Title: Oxidative Stress in children undergoing cardiopulmonary bypass: A trial of Sildenafil therapy
    Medical condition: Congenital Heart Disease
    Disease:
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-004727-18 Sponsor Protocol Number: CORUNO/II/05.1 Start Date*: 2008-06-20
    Sponsor Name:THERABEL PHARMACEUTICAL Ltd
    Full Title: EFFECT OF MOLSIDOMINE 16 MG ADMINISTERED ONCE-DAILY AS A LONG-TERM ADD-ON TREATMENT, ON ATHEROSCLEROSIS PROGRESSION AND INFLAMMATORY BIOMARKERS IN PATIENTS HOSPITALIZED FOR ACUTE CORONARY SYNDROME.
    Medical condition: Randomized, double-blind, placebo-controlled, add-on study in two parallel groups. Patients admitted for Non ST Segment Elevation Acute Coronary Syndromes will undergo a coronary angiography accord...
    Disease: Version SOC Term Classification Code Term Level
    7.0 10011085 HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-000425-22 Sponsor Protocol Number: 68-4986/12484 Start Date*: 2007-12-19
    Sponsor Name:Bayer Healthcare AG
    Full Title: Phase IIa Efficacy and Safety Trial of capadenoson in Patients with Chronic Stable Angina
    Medical condition: Patients with Chronic Stable Angina
    Disease: Version SOC Term Classification Code Term Level
    9.1 10049194 Stable angina pectoris LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2017-001216-11 Sponsor Protocol Number: FISAN-BOT-2017-01 Start Date*: 2017-04-25
    Sponsor Name:Dra. A. Teresa Calderón Duque
    Full Title: Usefulness of botulinum toxin type A in the treatment of chronic anal fissure
    Medical condition: Chronic anal fissure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-005435-98 Sponsor Protocol Number: version_2.0_dated_19.04.2011 Start Date*: 2012-06-21
    Sponsor Name:Śląski Uniwersytet Medyczny w Katowicach
    Full Title: A randomized, prospective, double-blind study with placebo to evaluate the efficacy of treatment of patients with angina resistant to pharmacological treatment and induced myocardial ischemia with...
    Medical condition: Stable angina pectoris CCS II-IV
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10049194 Stable angina pectoris LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: View results
    EudraCT Number: 2021-001564-26 Sponsor Protocol Number: TRIMETA Start Date*: 2022-04-15
    Sponsor Name:FONDAZIONE TOSCANA GABRIELE MONASTERIO
    Full Title: Evaluation of the cardioprotective metabolic effect of trimetazidine in patients with myocardial ischaemia
    Medical condition: Patients with clinical diagnosis of Inducible Myocardial Ischemia (exercise stress test positive for electrocardiographic criteria and /or symptoms)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10023033 Ischemia myocardial LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-002209-38 Sponsor Protocol Number: 7418-503 Start Date*: 2008-10-17
    Sponsor Name:NovaCardia, Inc. (A wholly owned subsidiary of Merck & Co., Inc.)
    Full Title: A multicenter, randomized, double-blind, placebo-controlled study of the hemodynamic effects of rolofylline injectable emulsion in the treatment of patients with heart failure
    Medical condition: Patients hospitalised with heart failure, volume overload and renal impairment, who require loop diuretic therapy and hemodynamic monitoring for clinical reasons
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000803 Acute heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) CZ (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-000397-23 Sponsor Protocol Number: SLx-2101-07-04 Start Date*: 2007-05-29
    Sponsor Name:Surface Logix, Inc.
    Full Title: A randomised, double blind, placebo-controlled, cross-over pilot study to examine the safety, tolerability and pharmacodynamic profile of repeat oral doses of SLx-2101 once daily for up to 14 days ...
    Medical condition: Raynaud's Disease
    Disease: Version SOC Term Classification Code Term Level
    8.1 10037917 Raynauds LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-002675-17 Sponsor Protocol Number: TIGER-BVS Start Date*: 2014-05-30
    Sponsor Name:Fundació Clínic per a la Recerca Biomèdica
    Full Title: Ticagrelor and absorb bioresorbable vascular scaffold implantation for recovery of vascular function after successful chronic total occlusion recanalization
    Medical condition: Chronic total coronary occlusion
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2008-003839-20 Sponsor Protocol Number: CVT5127 Start Date*: 2009-02-24
    Sponsor Name:Gilead Sciences, Inc.
    Full Title: A Open-Label, Parallel-Group, Exploratory Study to Evaluate the Efficacy and Safety of 400 µg Regadenoson Bolus for Pharmacological Stress Echocardiography
    Medical condition: Suspected coronary artery disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011078 Coronary artery disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-007093-37 Sponsor Protocol Number: ACV20616 Start Date*: 2009-05-27
    Sponsor Name:Actavis Deutschland GmbH & Co.Kg
    Full Title: Clinical efficacy of Pentalong® in stable Angina patients after 12 Weeks of routine administration:a randomised, double-blind, placebo-controlled trial.
    Medical condition: Stable, effort-induced angina pectoris
    Disease: Version SOC Term Classification Code Term Level
    13.1 10007541 - Cardiac disorders 10049194 Stable angina pectoris LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) BG (Completed) ES (Prematurely Ended) IS (Completed) HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-010236-18 Sponsor Protocol Number: CSPP100A2368 Start Date*: 2009-05-28
    Sponsor Name:Novartis Farmacéutica S.A.
    Full Title: Estudio multicéntrico, aleatorizado, doble ciego, de grupos paralelos, controlado con placebo para evaluar la eficacia y seguridad a 6 meses de la terapia de aliskiren, además de la terapia estánda...
    Medical condition: Insuficiencia Cardiaca aguda descompensada
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000803 Acute heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) DE (Completed) CZ (Completed) BE (Completed) IT (Completed) SK (Completed) PL (Completed) HU (Completed) SE (Completed) FI (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2011-001278-24 Sponsor Protocol Number: MEIN/10/Ran-Cad/003 Start Date*: 2011-09-02
    Sponsor Name:Menarini International Operations Luxembourg SA
    Full Title: EFFICACY OF RANOLAZINE IN PATIENTS WITH CORONARY ARTERY DISEASE (CAD)
    Medical condition: Excercise angina in patients with Coronary Artery Disease
    Disease: Version SOC Term Classification Code Term Level
    14.0 10007541 - Cardiac disorders 10014292 Effort angina LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed) ES (Completed) IE (Prematurely Ended) GB (Prematurely Ended) DE (Prematurely Ended) AT (Prematurely Ended) IT (Prematurely Ended) BG (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-001250-91 Sponsor Protocol Number: GV-002.001 Start Date*: 2005-10-04
    Sponsor Name:GenVec, Inc.
    Full Title: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy of BIOBYPASS® (ADGVVEGF121.10NH) Delivered by NOGA-Guided/MYOSTAR Catheter in "No Option" Patients with Cla...
    Medical condition: Moderate to severe angina pectoris due to advanced coronary artery disease (CAD).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) AT (Completed) DE (Completed) GB (Completed) BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-003266-87 Sponsor Protocol Number: CLCZ696B2401 Start Date*: 2016-03-02
    Sponsor Name:Novartis Pharma services AG
    Full Title: A multicenter, randomized, open label, parallel group study comparing pre-discharge and posT-discharge tReatment initiation with LCZ696 in heArt failure patieNtS with reduced ejectIon-fracTion hosp...
    Medical condition: Heart Failure with reduced ejection fraction (HF-rEF) stabilized after hospitalization due to acute decompensated heart failure episode.
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004849 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed) SK (Completed) PT (Completed) SE (Completed) ES (Completed) CZ (Completed) FR (Completed) BE (Completed) PL (Completed) HU (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-002319-26 Sponsor Protocol Number: D8830C00002 Start Date*: 2005-12-20
    Sponsor Name:AstraZeneca AB
    Full Title: Efficacy and safety of AZD9056 200 mg once daily versus placebo in adult patients with active Crohn’s disease – A randomized, double-blind, four week, parallel-group, multicentre, phase II study
    Medical condition: Crohn's disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) BE (Completed) AT (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2007-001794-28 Sponsor Protocol Number: 806 Start Date*: 2007-10-15
    Sponsor Name:OrbusNeich Medical BV
    Full Title: Endothelial Function following stenting with Genous vs Drug-Eluting Stents
    Medical condition: Patients with symptomatic ischemic heart disease expressing one or two de novo native coronary artery lesions
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011078 Coronary artery disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-000500-26 Sponsor Protocol Number: 01-1-101 Start Date*: Information not available in EudraCT
    Sponsor Name:Rapidscan Pharma Solutions EU Ltd (RPS EU Ltd)
    Full Title: An Open-label, Single Ascending-dose, Pharmacokinetic and Safety Study of Regadenoson (Rapidscan®) in Paediatric Patients with Cardiovascular Conditions and Diseases
    Medical condition: Regadenoson will be used as a pharmacologic stress agent in paediatric patients with cardiovascular problems, undergoing a clinically indicated myocardial perfusion MRI
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004848 10065141 Vascular diagnostic procedure LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2012-000196-17 Sponsor Protocol Number: 3/077/11 Start Date*: 2012-04-17
    Sponsor Name: [...]
    1.
    2. NHS Grampian, Aberdeen Royal Infirmary
    Full Title: The Effects of Inorganic Nitrite on cardiac and skeletal muscle: Physiology, pharmacology and therapeutic potential in patients suffering from Angina
    Medical condition: Chronic stable angina
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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