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Clinical trials for abt-494

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    The EU Clinical Trials Register currently displays   38161   clinical trials with a EudraCT protocol, of which   6268   are clinical trials conducted with subjects less than 18 years old.
    The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).
     
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    34 result(s) found for: abt-494. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2016-000674-38 Sponsor Protocol Number: M14-533 Start Date*: 2016-09-20
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: A Phase 3 Multicenter, Long-Term Extension Study to Evaluate the Safety and Efficacy of Upadacitinib (ABT-494) in Subjects with Ulcerative Colitis (UC)
    Medical condition: Ulcerative Colitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10017947 - Gastrointestinal disorders 10009900 Colitis ulcerative PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Ongoing) NL (Ongoing) CZ (Ongoing) AT (Ongoing) FI (Ongoing) PL (Ongoing) SE (Completed) GB (Ongoing) DE (Ongoing) LV (Ongoing) GR (Ongoing) EE (Ongoing) IE (Ongoing) HU (Ongoing) PT (Ongoing) LT (Ongoing) BE (Ongoing) NO (Ongoing) ES (Ongoing) HR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-004130-24 Sponsor Protocol Number: M15-572 Start Date*: 2017-07-27
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: A Phase 3, Randomized, Double-Blind, Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Subjects with Active Psoriatic Arthritis Who Have a History of Inadequate Response to at ...
    Medical condition: Moderately to Severely Active Psoriatic Arthritis
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004859 10037160 Psoriatic arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Ongoing) BE (Ongoing) DE (Ongoing) CZ (Ongoing) GB (Ongoing) GR (Ongoing) NL (Ongoing) PT (Ongoing) EE (Ongoing) LV (Ongoing) LT (Ongoing) SI (Ongoing) HU (Ongoing) ES (Ongoing) HR (Ongoing) BG (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-004409-17 Sponsor Protocol Number: M16-049 Start Date*: 2019-06-24
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: An Open-label Multiple-Dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Upadacitinib in Pediatric Subjects with Severe Atopic Dermatitis
    Medical condition: Severe Atopic Dermatitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10040785 - Skin and subcutaneous tissue disorders 10012438 Dermatitis atopic PT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: NO (Ongoing) NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-000641-31 Sponsor Protocol Number: M14-234 Start Date*: 2016-09-20
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Upadacitinib (ABT-494) for Induction and Maintenance Therapy in Subjects with Moderately to...
    Medical condition: Ulcerative Colitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10017947 - Gastrointestinal disorders 10009900 Colitis ulcerative PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Ongoing) NL (Ongoing) FI (Completed) HU (Ongoing) CZ (Ongoing) SE (Completed) PL (Ongoing) IE (Ongoing) PT (Ongoing) DE (Ongoing) LV (Ongoing) LT (Ongoing) AT (Ongoing) GR (Ongoing) BE (Ongoing) EE (Ongoing) NO (Ongoing) ES (Ongoing) GB (Ongoing) FR (Ongoing) HR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-002451-21 Sponsor Protocol Number: M16-048 Start Date*: 2016-12-22
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: A Phase 2b Multicenter, Randomized, Placebo-Controlled, Double-Blind Dose-Ranging Study to Evaluate ABT-494 in Adult Subjects with Moderate to Severe Atopic Dermatitis
    Medical condition: Atopic Dermatitis in adults
    Disease: Version SOC Term Classification Code Term Level
    19.1 10040785 - Skin and subcutaneous tissue disorders 10012438 Dermatitis atopic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) FI (Completed) IE (Completed) BE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2015-003759-23 Sponsor Protocol Number: M14-327 Start Date*: 2016-11-04
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: A Phase 2, Multicenter, Open-Label Extension (OLE) Study to Observe the Long-Term Efficacy, Safety, and Tolerability of Repeated Administration of Upadacitinib (ABT-494) in Subjects with Crohn's Di...
    Medical condition: Crohn's Disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004856 10013099 Disease Crohns LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Ongoing) GB (Ongoing) DE (Ongoing) NL (Ongoing) SK (Ongoing) CZ (Completed) BE (Ongoing) ES (Ongoing) HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-004152-30 Sponsor Protocol Number: M15-554 Start Date*: 2017-08-24
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: A Phase 3, Randomized, Double-Blind, Study Comparing Upadacitinib (ABT-494) to Placebo in Subjects with Active Psoriatic Arthritis Who Have a History of Inadequate Response to at Least One Biologi...
    Medical condition: Moderately to Severely Active Psoriatic Arthritis
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004859 10037160 Psoriatic arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Ongoing) CZ (Ongoing) GB (Ongoing) NL (Completed) FR (Ongoing) GR (Ongoing) PT (Ongoing) HU (Ongoing) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-003376-75 Sponsor Protocol Number: M15-555 Start Date*: 2016-06-23
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: A Phase 3, Randomized, Double-Blind Study Comparing ABT-494 Monotherapy to Methotrexate (MTX) in Subjects with Moderately to Severely Active Rheumatoid Arthritis with Inadequate Response to MTX
    Medical condition: Moderately to Severely Active Rheumatoid Arthritis (RA)
    Disease: Version SOC Term Classification Code Term Level
    19.0 10028395 - Musculoskeletal and connective tissue disorders 10039073 Rheumatoid arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing) GR (Ongoing) CZ (Ongoing) BE (Ongoing) PL (Ongoing) HU (Ongoing) PT (Ongoing) AT (Ongoing) BG (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-000715-25 Sponsor Protocol Number: M15-340 Start Date*: 2019-04-16
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: An Open-Label Multiple-Dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Upadacitinib in Pediatric Subjects with Polyarticular Course Juvenile Idiopathic Arthritis
    Medical condition: Polyarticular Course Juvenile Idiopathic Arthritis
    Disease: Version SOC Term Classification Code Term Level
    21.0 10028395 - Musculoskeletal and connective tissue disorders 10059176 Juvenile idiopathic arthritis PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Ongoing) HU (Ongoing) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-003335-35 Sponsor Protocol Number: M13-542 Start Date*: 2016-05-03
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: A Phase 3, Randomized, Double-Blind Study Comparing Upadacitinib (ABT-494) to Placebo on Stable Conventional Synthetic Disease-Modifying Anti-Rheumatic Drugs (csDMARDs) in Subjects with Moderately ...
    Medical condition: Moderately to Severely Active Rheumatoid Arthritis (RA)
    Disease: Version SOC Term Classification Code Term Level
    21.0 10028395 - Musculoskeletal and connective tissue disorders 10039073 Rheumatoid arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing) BE (Ongoing) IE (Ongoing) ES (Ongoing) DK (Completed) CZ (Ongoing) SE (Ongoing) GB (Ongoing) HU (Ongoing) SK (Ongoing) PT (Ongoing) LV (Ongoing) AT (Ongoing) FI (Ongoing) GR (Ongoing) FR (Completed) BG (Completed) SI (Ongoing) IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-003332-13 Sponsor Protocol Number: M13-549 Start Date*: 2016-01-12
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: A Phase 3, Randomized, Double-Blind Study Comparing ABT-494 to Placebo in Subjects with Moderately to Severely Active Rheumatoid Arthritis Who are on a Stable Dose of Conventional Synthetic Disease...
    Medical condition: Moderately to Severely Active Rheumatoid Arthritis (RA)
    Disease: Version SOC Term Classification Code Term Level
    21.0 10028395 - Musculoskeletal and connective tissue disorders 10039073 Rheumatoid arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Ongoing) ES (Ongoing) BG (Ongoing) CZ (Ongoing) DK (Completed) BE (Ongoing) IE (Ongoing) PT (Ongoing) GB (Ongoing) PL (Ongoing) LV (Ongoing) FI (Completed) NO (Ongoing) LT (Ongoing) HU (Ongoing) GR (Ongoing) AT (Completed) HR (Ongoing) IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-003978-13 Sponsor Protocol Number: M16-852 Start Date*: 2019-09-17
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Upadacitinib in Subjects with Giant Cell Arteritis: Select-GCA
    Medical condition: Giant Cell Arteritis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004866 10018250 Giant cell arteritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Ongoing) AT (Ongoing) DE (Restarted) PT (Ongoing) GR (Ongoing) HU (Ongoing) FR (Ongoing) BE (Ongoing) ES (Ongoing) NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-003334-27 Sponsor Protocol Number: M13-545 Start Date*: 2015-12-11
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: A Phase 3, Randomized, Double-Blind Study Comparing Upadacitinib (ABT-494) Once Daily Monotherapy to Methotrexate (MTX) Monotherapy in MTX-Naïve Subjects with Moderately to Severely Active Rheumato...
    Medical condition: Moderately to Severely Active Rheumatoid Arthritis (RA)
    Disease: Version SOC Term Classification Code Term Level
    21.0 10028395 - Musculoskeletal and connective tissue disorders 10039073 Rheumatoid arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Ongoing) SI (Ongoing) ES (Ongoing) GR (Ongoing) LT (Ongoing) BE (Ongoing) CZ (Ongoing) IE (Ongoing) LV (Ongoing) PL (Ongoing) GB (Ongoing) PT (Ongoing) HU (Ongoing) FI (Completed) HR (Ongoing) BG (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001240-35 Sponsor Protocol Number: M14-433 Start Date*: 2018-04-17
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: A Multicenter, Randomized, Double-Blind, Placebo Controlled Induction Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Subjects with Moderately to Severely Active Crohn's Disease Who H...
    Medical condition: Crohn's Disease (CD)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10017947 - Gastrointestinal disorders 10011401 Crohn's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Ongoing) SE (Ongoing) DE (Ongoing) AT (Ongoing) PT (Ongoing) BE (Ongoing) IE (Ongoing) GB (Ongoing) LV (Ongoing) HU (Ongoing) NL (Ongoing) PL (Ongoing) DK (Ongoing) LT (Ongoing) EE (Ongoing) ES (Ongoing) BG (Ongoing) HR (Ongoing) SI (Ongoing) FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001226-18 Sponsor Protocol Number: M14-431 Start Date*: 2018-04-17
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Induction Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Subjects with Moderately to Severely Active Crohn's Disease Who H...
    Medical condition: Crohn's Disease (CD)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10017947 - Gastrointestinal disorders 10011401 Crohn's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Ongoing) SE (Ongoing) DK (Ongoing) AT (Ongoing) PT (Ongoing) BE (Ongoing) IE (Ongoing) GB (Ongoing) LV (Ongoing) HU (Ongoing) DE (Ongoing) PL (Ongoing) CZ (Ongoing) LT (Ongoing) EE (Ongoing) ES (Ongoing) BG (Ongoing) SI (Ongoing) HR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001225-41 Sponsor Protocol Number: M14-430 Start Date*: 2018-04-17
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: A Multicenter, Randomized, Double-Blind, Placebo- Controlled Maintenance and Long-Term Extension Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Subjects with Crohn's Disease who Comp...
    Medical condition: Crohn's Disease (CD)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10017947 - Gastrointestinal disorders 10011401 Crohn's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Ongoing) DK (Ongoing) AT (Ongoing) DE (Ongoing) SE (Ongoing) LV (Ongoing) GB (Ongoing) PT (Ongoing) HU (Ongoing) NL (Ongoing) IE (Ongoing) LT (Ongoing) CZ (Ongoing) ES (Ongoing) BG (Ongoing) BE (Ongoing) SI (Ongoing) HR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-003333-95 Sponsor Protocol Number: M14-465 Start Date*: 2015-12-18
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: A Phase 3, Randomized, Double-Blind Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Subjects with Moderately to Severely Active Rheumatoid Arthritis Who are on a Stable Backg...
    Medical condition: Moderately to Severely Active Rheumatoid Arthritis (RA)
    Disease: Version SOC Term Classification Code Term Level
    21.0 10028395 - Musculoskeletal and connective tissue disorders 10039073 Rheumatoid arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Ongoing) ES (Ongoing) BG (Ongoing) HU (Ongoing) BE (Ongoing) DK (Prematurely Ended) IE (Ongoing) PT (Ongoing) GB (Ongoing) LV (Ongoing) AT (Prematurely Ended) DE (Ongoing) FI (Completed) CZ (Ongoing) HR (Ongoing) LT (Ongoing) GR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-003240-12 Sponsor Protocol Number: M13-740 Start Date*: 2015-06-19
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of ABT-494 for the Induction of Symptomatic and Endoscopic Remission in Subjects with Moderately to Severely Active Crohn's Disease...
    Medical condition: Crohn's Disease
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004856 10013099 Disease Crohns LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) HU (Completed) DE (Completed) ES (Completed) DK (Completed) NO (Completed) SK (Completed) NL (Completed) CZ (Completed) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2019-000638-20 Sponsor Protocol Number: M19-130 Start Date*: 2020-01-22
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: A Phase 2 Study to Investigate the Safety and Efficacy of Elsubrutinib and Upadacitinib Given Alone or in Combination (ABBV-599 Combination) in Subjects with Moderately to Severely Active Systemic ...
    Medical condition: Systemic Lupus Erythematosus (SLE)
    Disease: Version SOC Term Classification Code Term Level
    21.1 10028395 - Musculoskeletal and connective tissue disorders 10042945 Systemic lupus erythematosus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing) ES (Ongoing) HU (Ongoing) NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-002358-57 Sponsor Protocol Number: M13-550 Start Date*: 2014-03-11
    Sponsor Name:AbbVie Inc.
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study to investigate the Safety and Efficacy of ABT-494 Given with Methotrexate (MTX) in Subjects with Moderately to Severely Active Rheumato...
    Medical condition: Moderately to Severely Active Rheumatoid Arthritis (RA)
    Disease: Version SOC Term Classification Code Term Level
    17.0 10028395 - Musculoskeletal and connective tissue disorders 10039073 Rheumatoid arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) CZ (Completed) HU (Completed) NL (Completed) BE (Completed)
    Trial results: View results
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