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Clinical trials for hyperthyroidism

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44132   clinical trials with a EudraCT protocol, of which   7324   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    60 result(s) found for: hyperthyroidism. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2017-005050-11 Sponsor Protocol Number: SeMMIviD Start Date*: 2019-03-08
    Sponsor Name:A.O. OSPEDALE DI CIRCOLO E FONDAZIONE MACCHI
    Full Title: Effects of Selenium and cholecalciferol on hyperthyroidism due to Graves' disease treated with methimazole: a randomized, clinical, open label, pilot trial
    Medical condition: Graves' disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 10014698 - Endocrine disorders 10020850 Hyperthyroidism PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-003579-21 Sponsor Protocol Number: RAI2012 Start Date*: 2012-09-25
    Sponsor Name:FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO DI MILANO
    Full Title: Effect of the withdrawal of anti-thyroid treatment on the iodide 123 kynetics used for the dosmetry before radioiodine therapy with 131I for autoimmune hyperthyroidism.
    Medical condition: Autoimmune hyperthyroidism (Graves-Basedow disease)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10014698 - Endocrine disorders 10043739 Thyroid gland disorders HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-002127-26 Sponsor Protocol Number: BAFFI_14 Start Date*: 2015-10-13
    Sponsor Name:FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO
    Full Title: Randomized, single-blind, controlled study of the anti-BAFF antibody belimumab or methylprednisolone treatment in hyperthyroid Graves' disease (GD) and active orbitopathy (GO)
    Medical condition: GRAVES' ORBITOPATHY
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004853 10057889 Graves' ophthalmopathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-002894-27 Sponsor Protocol Number: IMVT-1401-2501 Start Date*: 2023-04-03
    Sponsor Name:Immunovant Sciences GmbH
    Full Title: A Proof-of-Concept, Open-label Study to Assess the Safety and Efficacy of Batoclimab in Participants with Graves’ Disease (GD)
    Medical condition: Graves` disease
    Disease: Version SOC Term Classification Code Term Level
    26.0 10014698 - Endocrine disorders 10018706 Graves' disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2021-001941-11 Sponsor Protocol Number: 2021-1798 Start Date*: 2021-09-09
    Sponsor Name:Rijnstate hospital
    Full Title: Ultrasound-guided radiofrequency ablation versus radioactive iodine as treatment for hyperthyroidism caused by solitary autonomous thyroid nodules.
    Medical condition: Patients > 18 years with (subclinical) hyperthyroidism caused by a solitary hyperactive thyroid nodules, either as a solitary hyperactive node in an otherwise normal thyroid gland or as a single hy...
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004860 10043753 Thyroid nodule (toxic) LLT
    20.0 100000004860 10043791 Thyrotoxicosis from ectopic thyroid nodule LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-005564-41 Sponsor Protocol Number: CCFZ533X2205 Start Date*: 2016-06-01
    Sponsor Name:Novartis Pharma Services AG
    Full Title: An open label study to evaluate the safety and efficacy of 12 week treatment with CFZ533 in patients with Graves' disease
    Medical condition: Graves' disease
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004860 10018706 Graves' disease LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-022840-19 Sponsor Protocol Number: SEBA Start Date*: 2011-12-30
    Sponsor Name:Universitätsmedizin Mainz
    Full Title: A monocentric, randomized, placebo-controlled double-blind clinical trial to assess the efficacy of Selenium in Morbus Basedow
    Medical condition: Morbus Basedow
    Disease: Version SOC Term Classification Code Term Level
    14.0 10014698 - Endocrine disorders 10004161 Basedow's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-003515-38 Sponsor Protocol Number: GO-TXATD Start Date*: 2016-02-23
    Sponsor Name:Medical University of Vienna
    Full Title: Prospective Randomized Clinical Trial of Total Thyroidectomy (Tx) versus Thionamides (Anti-Thyroid Drugs) in Patients with Moderate-to-Severe Graves’ Ophthalmopathy - a 1-year Follow-up
    Medical condition: Graves' disease, hyperthyroidism
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-002123-93 Sponsor Protocol Number: MINGO Start Date*: 2009-07-30
    Sponsor Name:Johannes Gutenberg-Universität
    Full Title: Mycophenolate sodium in Graves’ orbitopathy
    Medical condition: Graves' orbitopathy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10065624 Graves-Basedow disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-014361-14 Sponsor Protocol Number: 577/09 Start Date*: 2010-01-13
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: EVALUATION OF FEASIBILITY OF RITUXIMAB BY INTRALESIONAL INJECTION IN PATIENTS WITH GRAVES OPHTALMOPATHY
    Medical condition: GRAVES OPHTALMOPATHY
    Disease: Version SOC Term Classification Code Term Level
    12.1 10065624 Graves-Basedow disease LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-002555-33 Sponsor Protocol Number: 2006.415 Start Date*: 2007-03-14
    Sponsor Name:HOSPICES CIVILS DE LYON
    Full Title: Comparaison de l'efficacité et de la tolérance de différentes doses de méthylprednisolone administrées par voie intraveineuse dans le traitement des formes actives et de sévérité moyenne d'orbitopa...
    Medical condition: orbitopathie basedowienne
    Disease: Version SOC Term Classification Code Term Level
    8.1 10015679 Exophthalmic goiter LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-000209-35 Sponsor Protocol Number: 7805 Start Date*: 2016-08-24
    Sponsor Name:Newcastle upon Tyne Hospitals NHS Foundation Trust
    Full Title: Adjuvant rituximab – a potential treatment for the young patient with Graves’ hyperthyroidism
    Medical condition: Graves' hyperthyroidism
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-001910-40 Sponsor Protocol Number: OPHT-120312 Start Date*: 2012-06-06
    Sponsor Name:Medizinische Universität Wien, Universitätsklinik für Klinische Pharmakologie
    Full Title: The effect of intravenous glucocorticoids on the tearfilm in eyes with thyroid-associated ophthalmopathy
    Medical condition: Thyroid-associated ophthalmopathy (TAO)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10014698 - Endocrine disorders 10065624 Graves-Basedow disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2018-001317-33 Sponsor Protocol Number: STAGO Start Date*: 2020-05-14
    Sponsor Name:AZIENDA OSPEDALIERO-UNIVERSITARIA PISANA
    Full Title: A Phase II, open-label, ophthalmological external investigator-blinded, single-center, randomized, superiority, no profit, pilot clinical trial to evaluate the effects of atorvastatin on Graves' Or...
    Medical condition: Graves’ orbitopathy is a disabling and disfiguring disease affecting the eyes observed in approximately 25-30% of patients with Graves’ disease. Its clinical manifestations include exophthalmos, in...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10014698 - Endocrine disorders 10004161 Basedow's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-001690-26 Sponsor Protocol Number: v30 Start Date*: 2005-02-11
    Sponsor Name:Craigavon Area Hospital Group Trust
    Full Title: The Low HDL On six Weeks statin therapy (LOW) study
    Medical condition: Dyslipidaemia (low HDL-cholesterol)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-002713-58 Sponsor Protocol Number: HZNP-TEP-302 Start Date*: 2018-08-13
    Sponsor Name:Horizon Therapeutics USA, Inc.
    Full Title: Multicenter, Safety and Efficacy, Open-Label Extension Study Evaluating Teprotumumab (HZN.001) Treatment in Subjects with Thyroid Eye Disease
    Medical condition: Thyroid Eye Disease (TED)
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004853 10057889 Graves' ophthalmopathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2018-004676-35 Sponsor Protocol Number: RVT-1401-2001 Start Date*: 2019-10-23
    Sponsor Name:Immunovant Sciences GmbH
    Full Title: ASCEND GO2: A Phase 2b, Multicenter, Randomized, Double-blind, Placebo-controlled Study of RVT-1401 for the Treatment of Patients with Active, Moderate to Severe Graves’ Ophthalmopathy
    Medical condition: Graves´Ophthalmopathy
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004853 10057889 Graves' ophthalmopathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) ES (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-001611-24 Sponsor Protocol Number: CAIN457ADE16 Start Date*: 2021-07-26
    Sponsor Name:Novartis Pharma GmbH
    Full Title: A two-year multi-center Phase 3 study to investigate the efficacy and safety of secukinumab in adult patients with active, moderate to severe thyroid eye disease (ORBIT), with a randomized, paralle...
    Medical condition: Active, moderate to severe thyroid eye disease
    Disease: Version SOC Term Classification Code Term Level
    20.1 10015919 - Eye disorders 10060742 Endocrine ophthalmopathy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-005924-16 Sponsor Protocol Number: M13-377 Start Date*: 2012-06-13
    Sponsor Name:Abbott Laboratories Ireland Limited
    Full Title: A 12-week, Double-blind, Randomized Study to Compare the Efficacy and Safety of Fixed Combinations of Fenofibrate /Simvastatin 145/20mg and Fenofibrate / Simvastatin 145/40mg Tablets vs. Matching M...
    Medical condition: Dyslipidemia
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004861 10058110 Dyslipidemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2016-002435-15 Sponsor Protocol Number: FiHM003 Start Date*: 2017-08-10
    Sponsor Name:Fundación de Investigación HM Hospitales
    Full Title: Pilot study to assess physical exercise intervention in neoadjuvant treatment with nab-paclitaxel in patients with triple negative breast cancer
    Medical condition: Supervised exercise regimen given during neoadjuvant chemotherapy for triple negative breast cancer patients.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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