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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44381   clinical trials with a EudraCT protocol, of which   7393   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,381 result(s) found. Displaying page 1,278 of 2,220.
    EudraCT Number: 2005-004668-22 Sponsor Protocol Number: SYR-322-MET-008 Start Date*: 2006-05-26
    Sponsor Name:Takeda Global Research & Development Center, Inc.
    Full Title: A multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Determine the Efficacy and safety of SYR110322 (SYR-322) When Used in Combination with Metformin in Subjects with Type 2 Diabetes
    Medical condition: Type II diabetes mellitus.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) HU (Completed) DE (Completed) ES (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2012-001355-38 Sponsor Protocol Number: AP24534-12-301 Start Date*: 2012-10-04
    Sponsor Name:ARIAD Pharmaceuticals, Inc
    Full Title: A Phase 3 Randomized, Open-Label Study of Ponatinib versus Imatinib in Adult Patients with Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase
    Medical condition: Chronic Myeloid Leukemia in Chronic Phase
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) DE (Completed) SE (Prematurely Ended) BE (Prematurely Ended) CZ (Prematurely Ended) NL (Prematurely Ended) IT (Prematurely Ended) ES (Prematurely Ended) FI (Prematurely Ended) SK (Completed) PT (Prematurely Ended) AT (Prematurely Ended) PL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-002022-10 Sponsor Protocol Number: NV21928 Start Date*: 2008-09-23
    Sponsor Name:F. Hoffmann-La Roche Ltd
    Full Title: Protocolo multicéntrico abierto en el que se proporciona interferón pegilado alfa-2a (PEGASYS®) en monoterapia o en combinación con ribavirina (COPEGUS®) a pacientes con hepatitis C crónica que han...
    Medical condition: Chronic hepatitis C Hepatitis C crónica
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008912 Chronic hepatitis C LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) AT (Completed) FR (Completed) IT (Prematurely Ended) DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-002781-66 Sponsor Protocol Number: C-08-16 Start Date*: 2008-12-04
    Sponsor Name:Alcon Research, Ltd.
    Full Title: A twelve-month, multicenter, double-masked study of Travoprost / Brinzolamide fixed combination QD AM and Travoprost / Brinzolamide fixed combination QD PM versus COSOPT BID in patients with open-a...
    Medical condition: Open-angle glaucoma or Ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030348 Open angle glaucoma LLT
    9.1 10030348 Open angle glaucoma PT
    9.1 10015919 Eye disorders SOC
    9.1 10030043 Ocular hypertension LLT
    9.1 10030043 Ocular hypertension PT
    9.1 10015919 Eye disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) FR (Completed) ES (Completed) BE (Completed) SE (Prematurely Ended) DK (Prematurely Ended) PL (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-001043-19 Sponsor Protocol Number: CLO-34100405 Start Date*: 2008-09-24
    Sponsor Name:Genzyme Europe BV
    Full Title: Phase III Randomized, Double-Blind, Controlled Study Comparing Clofarabine and Cytarabine versus Cytarabine Alone in Adult Patients 55 Years and Older with Acute Myelogenous Leukemia (AML) who have...
    Medical condition: Acute Myelogenous (Myeloid) Leukemia (AML)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000880 Acute myeloid leukaemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) FR (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-005886-36 Sponsor Protocol Number: EFC6016 Start Date*: 2008-07-03
    Sponsor Name:Sanofi -Aventis Recherche & De'veloppement
    Full Title: A randomized, double-blind, placebo-controlled, 2-arm parallel-group, multicenter study with a 24-week main treatment period and an extension assessing the efficacy and safety of AVE0010 in patient...
    Medical condition: Type II Diabetes
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) DE (Completed) FR (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-001564-31 Sponsor Protocol Number: AMB 222 Start Date*: 2005-10-07
    Sponsor Name:Myogen Inc.
    Full Title: A phase 2, Open-label, Multicenter Study Evaluating Ambrisentan in Subjects with Pulmonary Arterial Hypertension Who Have Previously Discontinued Endothelin Receptor Antagonist Therapy Due to Serum...
    Medical condition: Pulmonary Arterial Hypertension
    Disease: Version SOC Term Classification Code Term Level
    7.0 10037400 low
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2006-004606-97 Sponsor Protocol Number: PMR-EC-1209 Start Date*: 2007-02-22
    Sponsor Name:Astellas Pharma GmbH
    Full Title: A MULTICENTER, SINGLE-ARM, OPEN, CONVERSION STUDY FROM A CYCLOSPORINE (CyA) BASED IMMUNOSUPPRESSIVE REGIMEN TO A TACROLIMUS MODFIED RELEASE, FK506E (MR4), BASED IMMUNOSUPPRESSIVE REGIMEN IN KIDNEY ...
    Medical condition: Stable, adult kidney transplant recipients (at least 12 months post transplant) who are currently treated with cyclosporine and who meet the Inclusion and Exclusion Criteria will be enrolled.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10023438 Kidney transplant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) BE (Completed) DE (Completed) ES (Completed) CZ (Completed) HU (Completed) FI (Completed) SE (Completed) DK (Completed) AT (Completed) PT (Prematurely Ended) IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-000617-19 Sponsor Protocol Number: DOXIL-BCA-3001 Start Date*: 2004-09-13
    Sponsor Name:Johnson & Johnson Pharmaceutical Research and Development
    Full Title: A Randomized Controlled Study of Docetaxel Monotherapy or Docetaxel and DOXIL for the Treatment of Advanced Breast Cancer
    Medical condition: Breast cancer
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: HU (Completed) AT (Completed) ES (Completed) GB (Completed) DE (Completed) LT (Completed) LV (Completed) EE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-003839-68 Sponsor Protocol Number: 333369-EPY-3001/3004 Start Date*: 2006-11-09
    Sponsor Name:Janssen-Cilag International N.V.
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study to Evaluate the Efficacy, Safety and Tolerability of RWJ-333369 as Adjunctive Therapy in Subjects with Partial Onse...
    Medical condition: Partial Onset Epilepsy Seizures
    Disease: Version SOC Term Classification Code Term Level
    8.1 10015037 Epilepsy LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) SE (Prematurely Ended) DE (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2005-001490-95 Sponsor Protocol Number: ESPRIT 002: STALWART Start Date*: 2006-04-21
    Sponsor Name:National Institute of Allergy and Infectious Diseases (NIAID)
    Full Title: A Randomized, Open-Label, International Study of Subcutaneous Recombinant Interleukin-2 (rIL-2, Aldesleukin) with and without Concomitant Antiretroviral Therapy in Patients with HIV-1 Infection and...
    Medical condition: HIV infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed) PT (Completed) DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2008-000025-19 Sponsor Protocol Number: A0081183 Start Date*: 2008-05-12
    Sponsor Name:Pfizer, S.A.
    Full Title: "ESTUDIO DE PREGABALINA, ALEATORIZADO, DOBLE CIEGO, DE 6 SEMANAS DE DURACIÓN EN SUJETOS CON SÍNDROME DE PIERNAS INQUIETAS" RANDOMIZED, DOUBLE-BLIND, 6-WEEK STUDY OF PREGABALIN IN SUBJECTS WITH RES...
    Medical condition: "Síndrome de Piernas Inquietas (SPI)" Restless legs syndrome (RLS)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10058920 Restless legs syndrome LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed) AT (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-014916-37 Sponsor Protocol Number: A3051122 Start Date*: 2010-03-15
    Sponsor Name:PFIZER
    Full Title: "Estudio de fase 4, doble ciego, controlado con placebo, multicéntrico y de 12 semanas de duración para evaluar la seguridad y la eficacia del tartrato de Vareniclina (CP-526,555) 1 mg dos veces a...
    Medical condition: "Dejar de Fumar" "Smoking cessation"
    Disease: Version SOC Term Classification Code Term Level
    12.1 10053325 Smoking cessation therapy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) DE (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2008-006497-15 Sponsor Protocol Number: LD Start Date*: 2009-10-14
    Sponsor Name:Wilhelminen Krebsforschung GmbH
    Full Title: Lenalidomide and Dexamethasone for treatment of patients with acute myeloma (light chain)-induced renal failure
    Medical condition: There are two patient groups to be included into the study: 1) Patients with previously unknown MM and acute light chain induced renal failure 2) Patients with previously diagnosed MM, normal or...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) CZ (Completed) SK (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-017238-39 Sponsor Protocol Number: IPX066-B09-06 Start Date*: 2010-09-15
    Sponsor Name:Impax Laboratories, Inc., acting through its Impax Pharmaceuticals Division (Impax)
    Full Title: A Study to Compare IPX066 and Carbidopa/Levodopa/Entacapone (CLE) in Advanced Parkinson’s Disease
    Medical condition: Idiopathic Parkinson’s Disease (paralysis agitans)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10061536 Parkinson's disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) IT (Completed) BE (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-019844-38 Sponsor Protocol Number: A6141116 Start Date*: 2010-08-12
    Sponsor Name:Pfizer, S.A
    Full Title: A double-blind, randomized, placebo-controlled trial evaluating the safety and efficacy of early the treatment with Eplerenone in patients with acute myocardial infarction. Estudio doble ciego, al...
    Medical condition: Infarto agudo de miocardio
    Disease: Version SOC Term Classification Code Term Level
    13 10000891 Infarto agudo de miocardio LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) SK (Completed) CZ (Completed) HU (Completed) GB (Completed) DE (Completed) NL (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2008-005232-33 Sponsor Protocol Number: FE200486 CS30 Start Date*: 2009-04-15
    Sponsor Name:Ferring Pharmaceuticals A/S
    Full Title: A randomised, parallel arm, open-label trial comparing degarelix with goserelin plus anti-androgen flare protection (bicalutamide), in terms of prostate size reduction in prostate cancer patients o...
    Medical condition: Prostate Cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10060862 Prostate cancer PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: NL (Completed) DE (Completed) FR (Completed) ES (Completed) GB (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2005-001841-40 Sponsor Protocol Number: GW685698X Start Date*: 2005-10-05
    Sponsor Name:GlaxoSmithKline Research And Development Ltd
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study to Evaluate the Efficacy and Safety of GW685698X Inhalation Powder 200mcg Twice-Daily, GW685698X Inhalation Powder ...
    Medical condition: Persistent asthma
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) LV (Prematurely Ended) DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-015400-26 Sponsor Protocol Number: ARQ 197-A-U251 Start Date*: 2010-03-04
    Sponsor Name:Daiichi Sankyo Pharma Development
    Full Title: MULTICENTER PHASE 2 TRIAL OF ARQ 197 FOR SUBJECTS WITH RELAPSED OR REFRACTORY GERM CELL TUMORS
    Medical condition: Germ cell tumors (GCT) including testicular and non-central nervous system (non-CNS) extragonadal types.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10061184 Germ cell cancer LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male
    Trial protocol: DE (Completed) FR (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-014246-29 Sponsor Protocol Number: BPS-MR-PAH-203 Start Date*: 2010-02-01
    Sponsor Name:Lung Rx
    Full Title: A 12-week, double-blind, international, multicenter, dose-response study of the safety and efficacy of Beraprost Sodium Modified Release (BPS-MR) in patients with pulmonary arterial hypertension (PAH)
    Medical condition: Pulmonary Arterial Hypertension
    Disease: Version SOC Term Classification Code Term Level
    12.0 10064911 Pulmonary arterial hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed) BE (Prematurely Ended) DE (Completed) CZ (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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