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Clinical trials for Cardiovascular Diseases AND Myocardial Ischemia AND Heart Diseases

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44393   clinical trials with a EudraCT protocol, of which   7405   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    119 result(s) found for: Cardiovascular Diseases AND Myocardial Ischemia AND Heart Diseases. Displaying page 2 of 6.
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    EudraCT Number: 2014-001354-42 Sponsor Protocol Number: IAMI-2014 Start Date*: 2014-12-16
    Sponsor Name:Örebro University Hospital
    Full Title: Influenza vaccination After Myocardial Infarction (IAMI trial). A multicenter, prospective, randomized controlled clinical trial based on national angiography and angioplasty registries
    Medical condition: Myocardial infarction
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10028596 Myocardial infarction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DK (Completed) LV (Completed) CZ (Completed) NO (Completed) GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2007-002931-95 Sponsor Protocol Number: LCC2010.01 Start Date*: 2008-01-30
    Sponsor Name:UZ Leuven
    Full Title: The Effects of Nitric Oxide for Inhalation on Myocardial Infarction Size.
    Medical condition: Myocardial Infarction
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10028596 Myocardial infarction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) DE (Prematurely Ended) HU (Completed)
    Trial results: View results
    EudraCT Number: 2019-003958-86 Sponsor Protocol Number: GS-US-356-5413 Start Date*: 2022-06-29
    Sponsor Name:Gilead Sciences, Inc.
    Full Title: Study of Females Exposed to Eleclazine
    Medical condition: The goal of this study is to follow up with female subjects who received eleclazine in prior clinical trials for ischemic heart disease, ventricular arrhythmia, hypertrophic cardiomyopathy or long ...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10055218 Ischemic heart disease LLT
    20.0 10010331 - Congenital, familial and genetic disorders 10020871 Hypertrophic cardiomyopathy PT
    20.1 10007541 - Cardiac disorders 10024803 Long QT syndrome PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Completed) IT (Completed) NL (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2021-001924-16 Sponsor Protocol Number: FDY-5301-302 Start Date*: 2022-04-13
    Sponsor Name:Faraday Pharmaceuticals, Inc.
    Full Title: IOCYTE AMI-3: A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Intravenous FDY-5301 in Patients with an Anterior ST-Elevation Myocardial Infarction
    Medical condition: Anterior ST-Elevation Myocardial Infarction
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10064346 STEMI LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Trial now transitioned) SK (Trial now transitioned) ES (Ongoing) PL (Trial now transitioned) PT (Trial now transitioned) CZ (Trial now transitioned) NL (Trial now transitioned) IT (Trial now transitioned)
    Trial results: View results
    EudraCT Number: 2020-005933-34 Sponsor Protocol Number: SFHI01 Start Date*: 2021-08-09
    Sponsor Name:Sorin CRM SAS (Microport CRM)
    Full Title: Evaluation of a modified Anti-Platelet Therapy associated with low-dose rapamycin DES Firehawk in Acute Myocardial Infarction Patients treated with complete revascularization strategy
    Medical condition: Patients with clinically stable, low to moderate complexity acute Myocardial Infarction (MI; troponine-positive Non-ST-Elevation MI or ST-Elevation MI) requiring primary Percutaneous Coronary Inte...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10007541 Cardiac disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) NL (Trial now transitioned) ES (Ongoing) IT (Ongoing) PT (Completed)
    Trial results: View results
    EudraCT Number: 2015-003895-65 Sponsor Protocol Number: DAL-301 Start Date*: 2016-06-22
    Sponsor Name:DalCor Pharma UK Ltd, Leatherhead, Swiss Branch Zug
    Full Title: A phase III, double-blind, randomized placebo-controlled study to evaluate the effects of dalcetrapib on cardiovascular (CV) risk in a genetically defined population with a recent Acute Coronary Sy...
    Medical condition: This study is investigating the cardiovascular morbidity and mortality (cardiovascular death, resuscitated cardiac arrest, non-fatal myocardial infarction (MI) and non-fatal stroke) in subjects wit...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10051592 Acute coronary syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) BE (Completed) SE (Completed) SK (Completed) DK (Completed) FI (Completed) PT (Completed) DE (Completed) HU (Completed) ES (Ongoing) AT (Completed) CZ (Completed) BG (Completed) RO (Ongoing) PL (Completed) GB (GB - no longer in EU/EEA) IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-004180-43 Sponsor Protocol Number: BAY59-7939/15786 Start Date*: 2013-03-13
    Sponsor Name:Bayer HealthCare AG
    Full Title: A randomized controlled trial of rivaroxaban for the prevention of major cardiovascular events in patients with coronary or peripheral artery disease (COMPASS - Cardiovascular OutcoMes for People u...
    Medical condition: Prevention of major cardiovascular events in patients with coronary or peripheral artery disease
    Disease: Version SOC Term Classification Code Term Level
    18.0 10042613 - Surgical and medical procedures 10064939 Cardiovascular event prophylaxis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed) SE (Completed) CZ (Completed) FI (Completed) IT (Completed) HU (Completed) NL (Completed) GB (Completed) SK (Completed) DK (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2022-001452-42 Sponsor Protocol Number: HCB.2021.1309 Start Date*: 2023-01-12
    Sponsor Name:HOSPITAL CLINIC BARCELONA
    Full Title: EVALUATION OF PATIENTS WITH TOTAL CORONARY OCCLUSIONS WITH MULTIMODALITY IMAGE
    Medical condition: Coronary artery chronic total occlusion
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-003050-41 Sponsor Protocol Number: HJE-PHARMA-001 Start Date*: 2015-11-10
    Sponsor Name:Rigshospitalet
    Full Title: Efficacy of GLP-1 agonists and restrictive vs. liberal FiO2 in patients undergoing coronary artery bypass grafting or aortic valve replacement – a 2-by-2 factorial designed, randomized clinical study
    Medical condition: We investigate the efficacy of commercially available GLP-1 analog for reducing organ damage in patients undergoing heart surgery (i.e. coronary artery bypass grafting and/or aortic valve replaceme...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000011627 10008937 Chronic ischemic heart disease, unspecified LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-004662-25 Sponsor Protocol Number: AMI-Study Start Date*: 2017-10-18
    Sponsor Name:Krakowski Szpital Specjalistyczny im. Jana Pawła II
    Full Title: Regeneration of ischemic damages in cardiovascular system using Wharton’s jelly as an unlimited source of mesenchymal stem cells for regenerative medicine. Project of the National Centre for Resear...
    Medical condition: AMI: Acute Myocardial Infarction
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10000891 Acute myocardial infarction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: View results
    EudraCT Number: 2017-000996-98 Sponsor Protocol Number: CSL112_3001 Start Date*: 2018-09-05
    Sponsor Name:CSL Behring LLC
    Full Title: A Phase 3, Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Investigate the Efficacy and Safety of CSL112 in Subjects with Acute Coronary Syndrome
    Medical condition: Acute Coronary Syndrome
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10000891 Acute myocardial infarction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Temporarily Halted) LV (Completed) SE (Completed) PT (Completed) FI (Completed) BE (Completed) LT (Completed) DK (Completed) EE (Completed) DE (Completed) AT (Completed) CZ (Completed) NO (Completed) HU (Completed) FR (Completed) NL (Completed) ES (Restarted) SK (Completed) BG (Completed) GR (Completed) HR (Completed) IT (Completed) RO (Ongoing)
    Trial results: View results
    EudraCT Number: 2015-000233-73 Sponsor Protocol Number: HCQvJan11 Start Date*: 2016-01-05
    Sponsor Name:Helsinki University Central Hospital
    Full Title: HYDROXYCHLOROQUINE IN ACUTE CORONARY SYNDROME: PREVENTION OF RECURRENT CARDIOVASCULAR EVENTS
    Medical condition: Cardiovascular disease
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-000487-15 Sponsor Protocol Number: CLSYN.1702 Start Date*: 2018-12-21
    Sponsor Name:Hamilton Health Sciences Corporation through its Population Health Research Institute
    Full Title: CLEAR SYNERGY (OASIS 9) A 2x2 factorial randomized controlled trial of CoLchicine and spironolactonE in patients with ST elevation myocARdial infarction/SYNERGY Stent Registry – Organization to Ass...
    Medical condition: ST segment Elevation Myocardial Infarction (STEMI)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10064345 ST segment elevation myocardial infarction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) FI (Completed) CZ (Completed) NL (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2021-002006-27 Sponsor Protocol Number: CKJX839B12302 Start Date*: 2021-11-15
    Sponsor Name:Novartis Pharma AG
    Full Title: A randomized, double-blind, placebo -controlled, multicenter trial, assessing the impact of inclisiran on major adverse cardiovascular events in participants with established cardiovascular disease...
    Medical condition: Atherosclerotic cardiovascular disease (ASCVD)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004866 10051615 Atherosclerotic cardiovascular disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned) SK (Trial now transitioned) PT (Trial now transitioned) LT (Trial now transitioned) NL (Trial now transitioned) IT (Trial now transitioned) AT (Trial now transitioned) LV (Trial now transitioned) HU (Trial now transitioned) SE (Trial now transitioned) DK (Trial now transitioned) BE (Trial now transitioned) SI (Trial now transitioned) BG (Trial now transitioned) HR (Trial now transitioned) NO (Trial now transitioned) PL (Trial now transitioned) FI (Trial now transitioned) GR (Trial now transitioned) IS (Trial now transitioned) RO (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-004591-22 Sponsor Protocol Number: HS-2017-01 Start Date*: 2017-03-14
    Sponsor Name:Medical University of Graz/Department of Internal Medicine/Division of Endocrinology and Diabetology
    Full Title: Impact of EMpagliflozin on cardiac function and biomarkers of heart failure in patients with acute MYocardial infarction (EMMY-Trial) – a phase III Study
    Medical condition: Myocardial infarction
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-008298-77 Sponsor Protocol Number: CV185-068 Start Date*: 2009-04-14
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: Apixaban for Prevention of Acute Ischemic Events - 2 A Phase 3, Randomized, Double-Blind, Evaluation of the Safety and Efficacy of Apixaban In Subjects with a Recent Acute Coronary Syndrome
    Medical condition: Subjects with a recent acute coronary syndrome (ACS) and at least 2 additional risk factors for recurrent ischemic events.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10051592 Acute coronary syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) AT (Prematurely Ended) NL (Prematurely Ended) SE (Prematurely Ended) NO (Completed) ES (Prematurely Ended) FI (Prematurely Ended) GB (Prematurely Ended) IT (Prematurely Ended) DK (Completed) CZ (Prematurely Ended) BE (Completed) HU (Prematurely Ended) DE (Completed) BG (Prematurely Ended) SK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2021-005618-32 Sponsor Protocol Number: 2021-HJEPharma-002 Start Date*: 2022-06-29
    Sponsor Name:Rigshospitalet
    Full Title: Dexamethasone, olanzapine, flow-targeted versus pressure-targeted hemodynamic management, and low tidal volume ventilation in patients undergoing on-pump cardiac surgery – a multifactorial design r...
    Medical condition: We investigate the efficacy of two pharmaceutical interventions for reducing mortality and organ damage, and shortening length of hospital stay in patients undergoing heart surgery (i.e. coronary a...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10008937 Chronic ischemic heart disease, unspecified LLT
    21.1 10042613 - Surgical and medical procedures 10061994 Heart valve operation PT
    20.0 10007541 - Cardiac disorders 10011085 Ischaemic coronary artery disorders HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2021-002557-29 Sponsor Protocol Number: SK_DMDPA-03 Start Date*: 2021-10-25
    Sponsor Name:Synektik Spółka Akcyjna
    Full Title: A Phase III Study of [11C]-DMDPA Tracer for Positron Emission Tomography PET-CT Myocardial Perfusion Imaging (MPI).
    Medical condition: Known or suspected acute coronary syndrome
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10011078 Coronary artery disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-001834-25 Sponsor Protocol Number: MasterDapt Start Date*: 2017-11-07
    Sponsor Name:ECRI-9
    Full Title: MAnagement of high bleeding risk patients post bioresorbable polymer coated STEnt implantation with an abbReviated versus prolonged DAPT regimen – MASTER DAPT
    Medical condition: High bleeding risk population represents a significant proportion of coronary artery disease (CAD) patients undergoing coronary stent implantation. Decisions regarding the duration of dual antiplat...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10007541 Cardiac disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) ES (Completed) SE (Completed) DE (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-005568-40 Sponsor Protocol Number: LoDoCo2 Start Date*: 2016-08-01
    Sponsor Name:Werkgroep Cardiologische centra Nederland
    Full Title: Low-dose colchicine for secondary prevention of cardiovascular disease
    Medical condition: cardiovascular disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10011082 Coronary artery disorders HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
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